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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines
Authors: Gisele Nishiguchi , Lauren G Mascibroda , Sarah M Young , Elizabeth A Caine , Sherif Abdelhamed , Jeffrey J Kooijman , Darcie J Miller , Sourav Das , Kevin McGowan , Anand Mayasundari , Zhe Shi , Juan M Barajas , Ryan Hiltenbrand , Anup Aggarwal , Yunchao Chang , Vibhor Mishra , Shilpa Narina , Melvin Thomas , Allister J Loughran , Ravi Kalathur , Kaiwen Yu , Suiping Zhou , Xusheng Wang , Anthony A High , Junmin Peng , Shondra M Pruett-Miller , Danette L Daniels , Marjeta Urh , Anang A Shelat , Charles G Mullighan , Kristin M Riching , Guido J R Zaman , Marcus Fischer , Jeffery M Klco , Zoran Rankovic
Journal: Nat Commun
PubMed ID: 38228616
Doi: 10.1038/s41467-024-44698-1
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Development of Moloney Murine Leukemia Virus Reverse Transcriptase Fused with Archaeal DNA-binding Protein Sis7a
Authors: Goldyna M Simanjuntak, Azzania Fibriani, Amalia A Fananda, Nicholas Yamahoki
Journal: Recent Pat Biotechnol
PubMed ID: 37016518
Doi: 10.2174/1872208317666230403104302
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Nanobodies as potential tools for microbiological testing of live biotherapeutic products
Authors: Robert J Dorosky, Jeremy E Schreier, Stephanie L Lola, Rosa L Sava, Michael P Coryell, Adovi Akue, Mark KuKuruga, Paul E Carlson, Sheila M Dreher-Lesnick, Scott Stibitz
Journal: AMB Express
PubMed ID: 38245586
Doi: 10.1186/s13568-023-01659-z
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Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
Authors: Anna Worthmann , Julius Ridder , Sharlaine Y L Piel , Ioannis Evangelakos , Melina Musfeldt , Hannah Voß , Marie O'Farrell , Alexander W Fischer , Sangeeta Adak , Monica Sundd , Hasibullah Siffeti , Friederike Haumann , Katja Kloth , Tatjana Bierhals , Markus Heine , Paul Pertzborn , Mira Pauly , Julia-Josefine Scholz , Suman Kundu , Marceline M Fuh , Axel Neu , Klaus Tödter , Maja Hempel , Uwe Knippschild , Clay F Semenkovich , Hartmut Schlüter , Joerg Heeren , Ludger Scheja , Christian Kubisch , Christian Schlein
Journal: Nat Commun
PubMed ID: 38167725
Doi: 10.1038/s41467-023-44364-y
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Molecular mechanisms and evolutionary robustness of a color switch in proteorhodopsins
Authors: Jiafei Mao, Xinsheng Jin, Man Shi, David Heidenreich, Lynda J Brown, Richard C D Brown, Moreno Lelli, Xiao He, Clemens Glaubitz
Journal: Sci Adv
PubMed ID: 38266078
Doi: 10.1126/sciadv.adj0384
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Motility-related microRNAs identified in pig seminal plasma exosomes by high-throughput small RNA sequencing
Authors: Yunxiang Zhao, Jiali Qin, Jingshuai Sun, Jian He, Yanmei Sun, Renqiang Yuan, Zhili Li
Journal: Theriogenology
PubMed ID: 38150851
Doi: 10.1016/j.theriogenology.2023.11.028
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ALOX5 deficiency contributes to bladder cancer progression by mediating ferroptosis escape
Authors: Tianyao Liu, Xinyan Xu, Jiazheng Li, Ming Bai, Wenjie Zhu, Yanqing Liu, Siyang Liu, Zihan Zhao, Tianhang Li, Ning Jiang, Yuhao Bai, Qingyang Jin, Yulin Zhang, Yufeng Zheng, Shengkai Zhou, Shoubin Zhan, Ying Sun, Gaoli Liang, Yang Luo, Xi Chen, Hongqian Guo, Rong Yang
Journal: Cell Death Dis
PubMed ID: 38062004
Doi: 10.1038/s41419-023-06333-7
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Enhancing CAR-T cells: unleashing lasting impact potential with phytohemagglutinin activation in in vivo leukemia model
Authors: Berranur Sert, Gamze Gulden, Tarik Teymur, Yasin Ay, Raife Dilek Turan, Onur Mert Unaldi, Elanur Guzenge, Hamza Emir Erdil, Sevim Isik, Pinar Oz, Ilknur Bozkurt, Samed Ozer, Tahire Yurdakul, Osman Kamali, Ercument Ovali, Nevzat Tarhan, Cihan Tastan
Journal: Cancer Gene Ther
PubMed ID: 38092962
Doi: 10.1038/s41417-023-00709-9
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Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway
Authors: Karim H Saba, Valeria Difilippo, Michal Kovac, Louise Cornmark, Linda Magnusson, Jenny Nilsson, Hilda van den Bos, Diana Cj Spierings, Mahtab Bidgoli, Tord Jonson, Vaiyapuri P Sumathi, Otte Brosjö, Johan Staaf, Floris Foijer, Emelie Styring, Michaela Nathrath, Daniel Baumhoer, Karolin H Nord
Journal: J Pathol
PubMed ID: 38010733
Doi: 10.1002/path.6219
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FGFR1 expression correlates inversely with the efficacy of single-agent FGFR-specific inhibitors in pancreatic cancer
Authors: Qingxiang Lin, Andrea Serratore, Jonathan Perri, Tista Roy Chaudhuri, Jun Qu, Wen Wee Ma, Eugene Kandel, Robert M Straubinger
Journal: Br J Pharmacol
PubMed ID: 37994108
Doi: 10.1111/bph.16289
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