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Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences
Authors: Morgan RA, Ma F, Unti MJ, Brown D, Ayoub PG, Tam C, Lathrop L, Aleshe B, Kurita R, Nakamura Y, Senadheera S, Wong RL, Hollis RP, Pellegrini M, Kohn DB
Journal: Molecular therapy. Methods & clinical development
PubMed ID: 32426415
Doi: 10.1016/j.omtm.2020.04.006
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Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes
Authors: Luppino JM, Park DS, Nguyen SC, Lan Y, Xu Z, Yunker R, Joyce EF
Journal: Nature Genetics
PubMed ID: 32572210
Doi: 10.1038/s41588-020-0647-9
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A regulatory role for CHD2 in myelopoiesis
Authors: Shahin Varnoosfaderani F, Palau A, Dong W, Persson J, Durand-Dubief M, Svensson JP, Lennartsson A
Journal: Epigenetics
PubMed ID: 31900031
Doi: 10.1080/15592294.2019.1710913
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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
Authors: Ozkan-Dagliyan I, Diehl JN, George SD, Schaefer A, Papke B, Klotz-Noack K, Waters AM, Goodwin CM, Gautam P, Pierobon M, Peng S, Gilbert TSK, Lin KH, Dagliyan O, Wennerberg K, Petricoin EF 3rd, Tran NL, Bhagwat SV, Tiu RV, Peng SB, Herring LE, Graves LM, Sers C, Wood KC, Cox AD, Der CJ
Journal: Cell Reports
PubMed ID: 32553168
Doi: 10.1016/j.celrep.2020.107764
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Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
Authors: Liu M, Lu Y, Yang B, Chen Y, Radda JSD, Hu M, Katz SG, Wang S
Journal: Nature Communications
PubMed ID: 32518300
Doi: 10.1038/s41467-020-16732-5
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Dynamics of the 4D genome during in vivo lineage specification and differentiation
Authors: Oudelaar AM, Beagrie RA, Gosden M, de Ornellas S, Georgiades E, Kerry J, Hidalgo D, Carrelha J, Shivalingam A, El-Sagheer AH, Telenius JM, Brown T, Buckle VJ, Socolovsky M, Higgs DR, Hughes JR
Journal: Nature Communications
PubMed ID: 32483172
Doi: 10.1038/s41467-020-16598-7
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Cell-Free Bacteriophage Genome Synthesis Using Low-Cost Sequence-Verified Array-Synthesized Oligonucleotides
Authors: Yeom H, Ryu T, Lee AC, Noh J, Lee H, Choi Y, Kim N, Kwon S
Journal: ACS Synthetic Biology
PubMed ID: 32383864
Doi: 10.1021/acssynbio.0c00051
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Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids
Authors: Michels BE, Mosa MH, Streibl BI, Zhan T, Menche C, Abou-El-Ardat K, Darvishi T, Członka E, Wagner S, Winter J, Medyouf H, Boutros M, Farin HF
Journal: Cell Stem Cell
PubMed ID: 32348727
Doi: 10.1016/j.stem.2020.04.003
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Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies
Authors: Li K, Zhang Y, Liu X, Liu Y, Gu Z, Cao H, Dickerson KE, Chen M, Chen W, Shao Z, Ni M, Xu J
Journal: Cancer Discovery
PubMed ID: 32188707
Doi: 10.1158/2159-8290.CD-19-1128
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Generalizable sgRNA design for improved CRISPR/Cas9 editing efficiency
Authors: Hiranniramol K, Chen Y, Liu W, Wang X
Journal: Bioinformatics (Oxford, England)
PubMed ID: 31971562
Doi: 10.1093/bioinformatics/btaa041
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