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Identification of ACE2 modifiers by CRISPR screening
Authors: Emily J Sherman, Carmen Mirabelli, Vi T Tang, Taslima G Khan, Andrew A Kennedy, Sarah E Graham, Cristen J Willer, Andrew W Tai, Jonathan Z Sexton, Christiane E Wobus, Brian T Emmer
Journal: biorxiv
PubMed ID: 34127970
Doi: 10.1101/2021.06.10.447768
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Large-Scale Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities
Authors: Li-Fu Song, Zheng-Hua Deng, Zi-Yi Gong, Lu-Lu Li, Bing-Zhi Li
Journal: Front Bioeng Biotechnol
PubMed ID: 34239862
Doi: 10.3389/fbioe.2021.689797
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CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy
Authors: Fraser Soares, Branson Chen, Jong Bok Lee, Musaddeque Ahmed, Dalam Ly, Enoch Tin, Hyeonjeong Kang, Yong Zeng, Nayeema Akhtar, Mark D Minden, Housheng Hansen He, Li Zhang
Journal: Blood
PubMed ID: 33270841
Doi: 10.1182/blood.2019004108
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Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase
Authors: Jing Li, Barun Mahata, Mario Escobar, Jacob Goell, Kaiyuan Wang, Pranav Khemka, Isaac B Hilton
Journal: Nat Commun
PubMed ID: 33563994
Doi: 10.1038/s41467-021-21188-2
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Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells
Authors: Zhu XG, Chudnovskiy A, Baudrier L, Prizer B, Liu Y, Ostendorf BN, Yamaguchi N, Arab A, Tavora B, Timson R, Heissel S, de Stanchina E, Molina H, Victora GD, Goodarzi H, Birsoy K
Journal: Cell metabolism
PubMed ID: 33152324
Doi: 10.1016/j.cmet.2020.10.017
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Antigen identification for HLA class I- and HLA class II-restricted T cell receptors using cytokine-capturing antigen-presenting cells
Authors: Mark N Lee, Matthew Meyerson
Journal: Sci Immunol
PubMed ID: 33483338
Doi: 10.1126/sciimmunol.abf4001
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enAsCas12a Enables CRISPR-Directed Evolution to Screen for Functional Drug Resistance Mutations in Sequences Inaccessible to SpCas9
Authors: Neggers JE, Jacquemyn M, Dierckx T, Kleinstiver BP, Thibaut HJ, Daelemans D
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
PubMed ID: 33002419
Doi: 10.1016/j.ymthe.2020.09.025
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A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis
Authors: Li Li, Alejandro P Ugalde, Colinda L G J Scheele, Sebastian M Dieter, Remco Nagel, Jin Ma, Abhijeet Pataskar, Gozde Korkmaz, Ran Elkon, Miao-Ping Chien, Li You, Pin-Rui Su, Onno B Bleijerveld, Maarten Altelaar, Lyubomir Momchev, Zohar Manber, Ruiqi Han, Pieter C van Breugel, Rui Lopes, Peter Ten Dijke, Jacco van Rheenen, Reuven Agami
Journal: Genome Biol
PubMed ID: 33514403
Doi: 10.1186/s13059-021-02272-8
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Mapping Genetic Interactions in Human Cancer Cells Using a One-Step tRNA-CRISPR System
Authors: Derek Yisen Zhang, Xiong Gui, Xiaolong Yang
Journal: Methods Mol Biol
PubMed ID: 34590276
Doi: 10.1007/978-1-0716-1740-3_9
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Functional Atlas of Primary miRNA Maturation by the Microprocessor
Authors: Rice GM, Shivashankar V, Ma EJ, Baryza JL, Nutiu R
Journal: Molecular Cell
PubMed ID: 33188727
Doi: 10.1016/j.molcel.2020.10.028
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