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Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
Authors: Dingfeng Li, Xinyi Gao, Xiaolin Ma, Ming Wang, Chuandong Cheng, Tian Xue, Feng Gao, Yong Shen, Juan Zhang, Qiang Liu
Journal: Cell Metab
PubMed ID: 38458203
Doi: 10.1016/j.cmet.2024.02.011.
Products & Services: Custom DNA/RNA Oligos   
Unveiling a Shield of Hope: A Novel Multiepitope-Based Immunogen for Cross-Serotype Cellular Defense against Dengue Virus
Authors: Nilanshu Manocha, Daphné Laubreton, Xavier Robert, Jacqueline Marvel, Virginie Gueguen-Chaignon, Patrice Gouet, Prashant Kumar, Madhu Khanna
Journal: Vaccines (Basel)
PubMed ID: 38543950
Doi: 10.3390/vaccines12030316
Products & Services: Catalog Peptides   
Effective Gene Therapy for Metachromatic Leukodystrophy Achieved with Minimal Lentiviral Genomic Integrations
Authors: Lucas Tricoli, Sunetra Sase, Julia Hacker, Vi Pham, Sidney Smith, Maxwell Chappell, Laura Breda, Stephanie Hurwitz, Naoto Tanaka, Carlo Castruccio Castracani, Amaliris Guerra, Zhongqi Hou, Lars Schlotawa, Karthikeyan Radhakrishnan, Peter Kurre, Rebecca Ahrens-Nicklas, Laura Adang, Adeline Vanderver, Stefano Rivella
Journal: biorxiv
PubMed ID: 38559013
Doi: 10.1101/2024.03.14.584404
Products & Services: Molecular Biology Reagents   
Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability
Authors: Minhui Ye, Yingzhe Fang, Lu Chen, Zemin Song, Qing Bao, Fei Wang, Hao Huang, Jin Xu, Ziwen Wang, Ruijing Xiao, Meng Han, Song Gao, Hudan Liu, Baishan Jiang, Guoliang Qing
Journal: Nat Commun
PubMed ID: 38493213
Doi: 10.1038/s41467-024-46572-6
G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes
Authors: Guillaume Giraud, Mélanie Rodà, Pélagie Huchon, Maud Michelet, Sarah Maadadi, Daniel Jutzi, Roland Montserret, Marc-David Ruepp, Romain Parent, Christophe Combet, Fabien Zoulim, Barbara Testoni
Journal: Nucleic Acids Res
PubMed ID: 38113270
Doi: 10.1093/nar/gkad1200
Products & Services: Mutagenesis Services   
Occlusal force orchestrates alveolar bone homeostasis via Piezo1 in female mice
Authors: Yiling Yang, Qinggang Dai, Xin Gao, Yanfei Zhu, Mi Ri Chung, Anting Jin, Yuanqi Liu, Xijun Wang, Xiangru Huang, Siyuan Sun, Hongyuan Xu, Jingyi Liu, Lingyong Jiang
Journal: J Bone Miner Res
PubMed ID: 38477783
Doi: 10.1093/jbmr/zjae032
Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease
Authors: Stefano Soldano, Vanessa Smith, Paola Montagna, Emanuele Gotelli, Rosanna Campitiello, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Andrea Cere, Maurizio Cutolo
Journal: Arthritis Res Ther
PubMed ID: 38509595
Doi: 10.1186/s13075-024-03308-7
Zoledronic Acid Accelerates ER Stress-Mediated Inflammation by Increasing PDE4B Expression in Bisphosphonate-Related Osteonecrosis of the Jaw
Authors: Qu Xz, Sun Zq, Liu L, Ong Hs
Journal: Appl Biochem Biotechnol
PubMed ID: 38523176
Doi: 10.1007/s12010-024-04859-w
Products & Services: Gene Synthesis   
Structural determination and kinetic analysis of the transketolase from Vibrio vulnificus reveal unexpected cooperative behavior
Authors: Rainier-Numa Georges, Lionel Ballut, Guillaume Octobre, Arnaud Comte, Laurence Hecquet, Franck Charmantray, Bastien Doumèche
Journal: Protein Sci
PubMed ID: 38145310
Doi: 10.1002/pro.4884
Products & Services: Molecular Biology Reagents   
Supra-biological performance of immobilized enzymes enabled by chaperone-like specific non-covalent interactions
Authors: Héctor Sánchez-Morán, Joel L Kaar, Daniel K Schwartz
Journal: Nat Commun
PubMed ID: 38485940
Doi: 10.1038/s41467-024-46719-5
Products & Services: Molecular Biology Reagents   

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