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Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16

Authors: Huasong Ai , Zaozhen He, Zhiheng Deng, Guo-Chao Chu, Qiang Shi, Zebin Tong, Jia-Bin Li , Man Pan , Lei Liu

Journal: Nat Struct Mol Biol

PubMed ID: 38918638

Doi: doi.org/10.1038/s41594-024-01342-2

Products & Services: Codon Optimization

The ric-8b protein (resistance to inhibitors of cholinesterase 8b) is key to preserving contractile function in the adult heart

Authors: Elena Tsisanova, Muriel Nobles, Sonia Sebastian, Keat-Eng Ng, Alison Thomas, Lee Scott Weinstein, Patricia B Munroe, Andrew Tinker

Journal: J Biol Chem

PubMed ID: 38879012

Doi: 10.1016/j.jbc.2024.107470

Products & Services: Molecular Biology Reagents

Conservation of C4BP-binding Sequence Patterns in Streptococcus pyogenes M and Enn Proteins

Authors: Piotr Kolesiński, Matthew McGowan, Anne Botteaux, Pierre R Smeesters, Partho Ghosh

Journal: J Biol Chem

PubMed ID: 38879009

Doi: 10.1016/j.jbc.2024.107478

Products & Services: Proteins, Expression, Isolation and Analysis

Synthetic genomes unveil the effects of synonymous recoding

Authors: Akos Nyerges, Anush Chiappino-Pepe, Bogdan Budnik, Maximilien Baas-Thomas, Regan Flynn, Shirui Yan, Nili Ostrov, Min Liu, Meizhou Wang, Qingmei Zheng, Fangxiang Hu, Kangming Chen, Alexandra Rudolph, Dawn Chen, Jenny Ahn, Owen Spencer, Venkat Ayalavarapu, Angela Tarver, Miranda Harmon-Smith, Matthew Hamilton, Ian Blaby, Yasuo Yoshikuni, Behnoush Hajian, Adeline Jin, Balint Kintses, Monika Szamel, Viktoria Seregi, Yue Shen, Zilong Li, George M Church

Journal: biorxiv

PubMed ID: 38915524

Doi: 10.1101/2024.06.16.599206

Products & Services: Gene Synthesis

The Human Genetic Differences in the Outcomes of mRNA Vaccination against COVID-19: A Prospective Cohort Study

Authors: Ha-Eun Ryu, Jihyun Yoon, Ja-Eun Choi, Seok-Jae Heo, Kyung-Won Hong, Dong-Hyuk Jung

Journal: Vaccines (Basel)

PubMed ID: 38932355

Doi: 10.3390/vaccines12060626

Products & Services: Molecular Biology Reagents

PCNA molecular recognition of different PIP motifs: Role of Tyr211 phosphorylation

Authors: Antonio Ruiz-Albor, Belén Chaves-Arquero, Inés Martín-Barros, Alejandra Guerra-Castellano, Amaia Gonzalez-Magaña, Alain Ibáñez de Opakua, Nekane Merino, Mariola Ferreras-Gutiérrez, Edurne Berra, Irene Díaz-Moreno, Francisco J Blanco

Journal: Int J Biol Macromol

PubMed ID: 38880460

Doi: 10.1016/j.ijbiomac.2024.133187

Products & Services: Proteins, Expression, Isolation and Analysis

Enabling high-throughput enzyme discovery and engineering with a low-cost, robot-assisted pipeline

Authors: Brenna Norton-Baker, Mackenzie C R Denton, Natasha P Murphy, Benjamin Fram, Samuel Lim, Erika Erickson, Nicholas P Gauthier, Gregg T Beckham

Journal: Sci Rep

PubMed ID: 38914665

Doi: 10.1038/s41598-024-64938-0

Products & Services: Proteins, Expression, Isolation and Analysis

Interleukin-17A educated hepatic stellate cells promote hepatocellular carcinoma occurrence through fibroblast activation protein expression

Authors: Jun-Sheng Ni, Si-Yuan Fu, Zong-Yan Wang, Wen-Bin Ding, Jian Huang, Xing-Gang Guo, Fang-Ming Gu