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Rapid generation of long, chemically modified pegRNAs for prime editing

Authors: Xinlin Lei , Anhui Huang , Didi Chen , Xuebin Wang , Ruijin Ji , Jinlin Wang , Yizhou Zhang , Yuming Zhang , Shuhan Lu , Kun Zhang , Qiubing Chen , Ying Zhang , Hao Yin

Journal: Nature Biotechnology

PubMed ID: 39349835

Doi: doi.org/10.1038/s41587-024-02394-x

Products & Services: Custom DNA/RNA Oligos Gene Synthesis Synthetic sgRNA and crRNA Service

A bioorthogonal probiotic platform spatiotemporally releases nanobodies in deep tumor for cancer chemoimmunotherapy

Authors: Ruiyue Chen , Qianglan Lu , Fei Zeng , Shurong Qin , Yongchun Pan , Zhiyong Liu , Yuzhen Wang , Bangshun He , Wenjin Qi , Yujun Song

Journal: Materials Today

Doi: 10.1016/j.mattod.2024.09.002

Products & Services: Recombinant Proteins

Open-Source Throttling of CD8+ T Cells in Brain with Low-Intensity Focused Ultrasound-Guided Sequential Delivery of CXCL10, IL-2, and aPD-L1 for Glioblastoma Immunotherapy

Authors: Lei Dong , Yini Zhu , Haoge Zhang , Lin Gao , Zhiqi Zhang , Xiaoxuan Xu , Leqian Ying , Lu Zhang , Yue Li , Zhengcheng Yun , Danqi Zhu , Chang Han , Tingting Xu , Hui Yang , Shenghong Ju , Xiaoyuan Chen , Haijun Zhang , Jinbing Xie

Journal: ADVANCED MATERIALS

PubMed ID: 39264011

Doi: 10.1002/adma.202407235

Products & Services: Recombinant Proteins

Strontium-Modified porous attapulgite composite hydrogel scaffold with advanced angiogenic and osteogenic potential for bone defect repair

Authors: Chun Liu , Su Ni , Xiaoyu Wu , Linxiang Zhang , Ting Dai , Aiqin Wang , Hongbin Zhao

Journal: COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING

Doi: doi.org/10.1016/j.compositesa.2024.108492

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of antimicrobial bioactive peptides from the camel milk protein lactoferrin: Molecular docking, molecular dynamic simulation, and in vitro study

Authors: Mohammed Alzain , Ehab M.M. Ali , Mazin Zamzami , Ishtiaq Qadri , Hani Choudhry , Kamel Chaieb , Bochra Kouidhi , Hisham N. Altayb

Journal: food and humanity

Doi: doi.org/10.1016/j.foohum.2024.100414

Products & Services: Peptide Synthesis

Diffusiophoresis promotes phase separation and transport of biomolecular condensates

Authors: Viet Sang Doan , Ibraheem Alshareedah , Anurag Singh , Priya R Banerjee , Sangwoo Shin

Journal: Nature Communications

PubMed ID: 37461689

Doi: 10.1038/s41467-024-51840-6

Products & Services: Peptide Synthesis

Arabidopsis cryptochromes interact with SOG1 to promote the repair of DNA double-strand breaks

Authors: Li Chen , Minqing Liu , Yupeng Li , Yan Guan, Jiaqi Ruan , Zhilei Mao , Wenxiu Wang , Hong-Quan Yang , Tongtong Guo

Journal: BBRC

Doi: 10.1016/j.bbrc.2024.150233

Products & Services: Catalog Antibody

The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress

Authors: Ying Ma , Jiarong Guo , Haipeng Rao , Jingyu Xin , Xinyi Song , Rui Liu , Shan Shao , Jiajia Hou , Liyu Kong , Zhigang Hu , Lingfeng He , Feiyan Pan , Zhigang Guo

Journal: Journal of extracellular vesicles

PubMed ID: 39235072

Doi: 10.1002/jev2.12505

Products & Services: Gene Synthesis

Clathrin-associated carriers enable recycling through a kiss-and-run mechanism

Authors: Jiachao Xu, Yu Liang, Nan Li, Song Dang, Amin Jiang, Yiqun Liu, Yuting Guo, Xiaoyu Yang, Yi Yuan, Xinyi Zhang, Yaran Yang, Yongtao Du, Anbing Shi, Xiaoyun Liu, Dong Li, Kangmin He

Journal: Nature Cell Biology

PubMed ID: 39300312

Doi: 10.1038/s41556-024-01499-4

Products & Services: Molecular Biology Reagents

Chemoproteomic profiling unveils binding and functional diversity of endogenous proteins that interact with endogenous triplex DNA

Authors: Hongzhan Xu , Jing Ye # , Kui-Xing Zhang # , Qingxi Hu , Tongxiao Cui , Chong Tong , Mengqi Wang , Huichao Geng , Kun-Ming Shui , Yan Sun , Jian Wang , Xiaomeng Hou , Kai Zhang , Ran Xie , Yafei Yin , Nan Chen , Jia-Yu Chen

Journal: nature Chemistry

PubMed ID: 39223307

Doi: 10.1038/s41557-024-01609-7

Products & Services: Catalog Peptides

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