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页码: 168/1026 每页显示数量

Programmable nano-reactors for stochastic sensing

Authors: Wendong Jia, Chengzhen Hu, Yuqin Wang, Yuming Gu, Guangrui Qian, Xiaoyu Du, Liying Wang, Yao Liu, Jiao Cao, Shanyu Zhang, Shuanghong Yan, Panke Zhang, Jing Ma, Hong-Yuan Chen, Shuo Huang

Journal: Nat Commun.

PubMed ID: 34608151

Doi: 10.1038/s41467-021-26054-9

Products & Services: Single-Stranded DNA Synthesis

Structural basis of the P4B ATPase lipid flippase activity

Authors: Lin Bai, Bhawik K Jain, Qinglong You, H Diessel Duan, Mehmet Takar, Todd R Graham, Huilin Li

Journal: Nat Commun

PubMed ID: 34645814

Doi: 10.1038/s41467-021-26273-0

Products & Services: Proteins, Expression, Isolation and Analysis

Does poor glycaemic control affect the immunogenicity of the COVID-19 vaccination in patients with type 2 diabetes: The CAVEAT study

Authors: Raffaele Marfella, Nunzia D'Onofrio, Celestino Sardu, Lucia Scisciola, Paolo Maggi, Nicola Coppola, Ciro Romano, Vincenzo Messina, Fabrizio Turriziani, Mario Siniscalchi, Mauro Maniscalco, Marco Boccalatte, Giovanni Napolitano, Luigi Salemme, Ludovica Vittoria Marfella, Eugenio Basile, Maria Vittoria Montemurro, Carmela Papa, Francesco Frascaria, Antonio Papa, Ferdinando Russo, Virginia Tirino, Gianpaolo Papaccio, Marilena Galdiero, Ferdinando Carlo Sasso, Michelangela Barbieri, Maria Rosaria Rizzo, Maria Luisa Balestrieri, Italo Francesco Angelillo, Claudio Napoli, Giuseppe Paolisso

Journal: Diabetes Obes Metab

PubMed ID: 34494705

Doi: 10.1111/dom.14547

Products & Services: Serology SARS-Cov-2 detection kits

Identification and evaluation of an appropriate housekeeping gene for real time gene profiling of hepatocellular carcinoma cells cultured in three dimensional scaffold

Authors: Anjana Kaveri Badekila, Praveen Rai, Sudarshan Kini

Journal: Mol Biol Rep

PubMed ID: 34665400

Doi: 10.1007/s11033-021-06830-y

Products & Services: Molecular Biology Tools

Effect of Structural Changes Induced by Deletion of 54FLRAPSWF61 Sequence in αB-Crystallin on Chaperone Function and Anti-Apoptotic Activity

Authors: Sundararajan Mahalingam, Srabani Karmakar 1ORCID, Puttur Santhoshkumar, Krishna K. Sharma

Journal: International Journal of Molecular Sciences

PubMed ID: 34639110

Doi: 10.3390/ijms221910771

Products & Services: Proteins, Expression, Isolation and Analysis

Cytochalasin B-induced membrane vesicles from human mesenchymal stem cells overexpressing TRAIL, PTEN and IFN-β1 can kill carcinoma cancer cells

Authors: Daria S Chulpanova, Zarema E Gilazieva, Elvira R Akhmetzyanova, Sevindzh K Kletukhina, Albert A Rizvanov, Valeriya V Solovyeva

Journal: Tissue Cell

PubMed ID: 34678531

Doi: 10.1016/j.tice.2021.101664

Products & Services: PCR Cloning and Subcloning

Quantitative comparison of different fluorescent dye-loaded nanoparticles

Authors: Guangze Yang, Yun Liu, Chun-Xia Zhao

Journal: Colloids Surf B Biointerfaces

PubMed ID: 34146992

Doi: doi.org/10.1016/j.colsurfb.2021.111923

Products & Services: Peptide Synthesis

Transgenic genome editing-derived antiviral therapy to nucleopolyhedrovirus infection in the industrial strain of the silkworm

Authors: Xu Yang, Xiaoqian Zhang, Yujia Liu, Dehong Yang, Zulian Liu, Kai Chen, Linmeng Tang, Manli Wang, Zhihong Hu, Shengxiang Zhang, Yongping Huang

Journal: Insect Biochem Mol Biol

PubMed ID: 34700022

Doi: 10.1016/j.ibmb.2021.103672

Products & Services: GenCrispr Cas9 Genome Editing

Establishment of a pig CRISPR/Cas9 knockout library for functional gene screening in pig cells

Authors: Chuanzhao Yu, Haiwen Zhong, Xiaohui Yang, Guoling Li, Zhenfang Wu, Huaqiang Yang

Journal: Biotechnol J

PubMed ID: 34705337

Doi: 10.1002/biot.202100408

Products & Services: PCR Cloning and Subcloning

Tong‑fu‑li‑fei decoction attenuates immunosuppression to protect the intestinal‑mucosal barrier in sepsis by inhibiting the PD‑1/PD‑L1 signaling pathway

Authors: Li Chen, Lan Li, Suzhao Zou, Qianhua Liao, Bo Lv

Journal: Mol Med Rep

PubMed ID: 34633052

Doi: 10.3892/mmr.2021.12480

Products & Services: Nucleic Acid Purification & Analysis

Topmouth culter melanocortin-3 receptor: regulation by two isoforms of melanocortin-2 receptor accessory protein 2

Authors: Ren-Lei Ji, Lu Huang, Yin Wang, Ting Liu, Si-Yu Fan, Min Tao, Ya-Xiong Tao

Journal: Endocr Connect

PubMed ID: 34678761

Doi: 10.1530/EC-21-0459

Products & Services: Nucleic Acid Purification & Analysis

Determining folding and binding properties of the C-terminal SH2 domain of SHP2

Authors: Caterina Nardella, Francesca Malagrinò, Livia Pagano, Serena Rinaldo, Stefano Gianni, Angelo Toto

Journal: Protein Sci

PubMed ID: 34605082

Doi: 10.1002/pro.4201

Products & Services: Mutagenesis Services

Rapidly Declining SARS-CoV-2 Antibody Titers within 4 Months after BNT162b2 Vaccination

Authors: Dong-Ho Jo, Dohsik Minn, Jaegyun Lim, Ki-Deok Lee, Yu-Min Kang, Kang-Won Choe, Kwang-Nam Kim

Journal: Vaccines (Basel)

PubMed ID: 34696253

Doi: 10.3390/vaccines9101145

Products & Services: Mammalian Expression

Structural basis of cytokine-mediated activation of ALK family receptors

Authors: Steven De Munck, Mathias Provost, Michiko Kurikawa, Ikuko Omori, Junko Mukohyama, Jan Felix, Yehudi Bloch, Omar Abdel-Wahab, J Fernando Bazan, Akihide Yoshimi, Savvas N Savvides

Journal: Nature

PubMed ID: 34646012

Doi: 10.1038/s41586-021-03959-5

Products & Services: Mammalian Expression

Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients

Authors: Jonathan Marable, Damien Ruiz, Anil K Jaiswal, Ritankar Bhattacharya, Robert Pantazes, Payal Agarwal, Amol S Suryawanshi, Deepa Bedi, Amarjit Mishra, Bruce F Smith, Maninder Sandey

Journal: Sci Rep

PubMed ID: 34675296

Doi: 10.1038/s41598-021-00325-3

Products & Services: Endotoxin Detection & Removal System

The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37

Authors: David A Perez-Perez, Teresa de J Villanueva-Ramirez, Adriana E Hernandez-Pedraza, Nestor G Casillas-Vega, Patricia Gonzalez-Barranco, Xristo Zarate

Journal: Antibiotics (Basel)

PubMed ID: 34680851

Doi: 10.3390/antibiotics10101271

Products & Services: DNA Sequencing Gene Synthesis

Circular RNA circ_0090231 promotes atherosclerosis in vitro by enhancing NLR family pyrin domain containing 3-mediated pyroptosis of endothelial cells

Authors: Yishan Ge, Wenwu Liu, Wei Yin, Xuebin Wang, Jie Wang, Xiaoqing Zhu, Shengkai Xu

Journal: Bioengineered

PubMed ID: 34637670

Doi: 10.1080/21655979.2021.1989260

Products & Services: DNA Sequencing

Structure of Aedes aegypti carboxypeptidase B1-inhibitor complex uncover the disparity between mosquito and non-mosquito insect carboxypeptidase inhibition mechanism

Authors: Edem Gavor, Yeu Khai Choong, Chacko Jobichen, Yu Keung Mok, R Manjunatha Kini, J Sivaraman

Journal: Protein Sci

PubMed ID: 34658092

Doi: 10.1002/pro.4212

Products & Services: Custom Vector Construction

ChimLeish, a new recombinant chimeric protein evaluated as a diagnostic and prognostic marker for visceral leishmaniasis and human immunodeficiency virus coinfection

Authors: Nathalia C Galvani, Amanda S Machado, Daniela P Lage, Camila S Freitas, Danniele L Vale, Daysiane de Oliveira, Fernanda Ludolf, Fernanda F Ramos, Bruna B Fernandes, Gabriel P Luiz, Débora V C Mendonça, João A Oliveira-da-Silva, Thiago A R Reis, Grasiele S V Tavares, Ana T Chaves, Nathalia S Guimarães, Unaí Tupinambás, Gláucia F Cota, Maria V Humbert, Vívian T Martins, Myron Christodoulides, Eduardo A F Coelho, Ricardo A Machado-de-Ávila

Journal: Parasitol Res

PubMed ID: 34664113

Doi: 10.1007/s00436-021-07342-1

Products & Services: Custom Vector Construction

Discovery of a novel glucuronan lyase system in

Authors: Bo Pilgaard, Marlene Vuillemin, Line Munk, Jesper Holck, Sebastian Meier, Casper Wilkens, Anne S Meyer

Journal: Appl Environ Microbiol

PubMed ID: 34705548

Doi: 10.1128/AEM.01819-21

Products & Services: Custom Vector Construction

Analysis of IgG, IgA and IgM antibodies against SARS-CoV-2 spike protein S1 in convalescent and vaccinated patients with the Pfizer-BioNTech and CanSinoBio vaccines

Authors: Edgar A Melgoza-González, Diana Hinojosa-Trujillo, Mónica Reséndiz-Sandoval, Verónica Mata-Haro, Sofía Hernández-Valenzuela, Melissa García-Vega, Marlene Bravo-Parra, Aldo A Arvizu-Flores, Olivia Valenzuela, Edgar Velázquez, Alan Soto-Gaxiola, Martha B Gómez-Meza, Fernando Pérez-Jacobo, Luis Villela, Jesús Hernández

Journal: Transbound Emerg Dis

PubMed ID: 34655457

Doi: 10.1111/tbed.14344

Products & Services: Custom Vector Construction

Optimizing -Mediated Transformation and CRISPR-Cas9 Gene Editing in the Rice Variety Presidio

Authors: Marco Molina-Risco, Oneida Ibarra, Mayra Faion-Molina, Backki Kim, Endang M Septiningsih, Michael J Thomson

Journal: Int J Mol Sci

PubMed ID: 34681568

Doi: 10.3390/ijms222010909

Products & Services: Custom Vector Construction

CircSOD2: A Novel Regulator for Smooth Muscle Proliferation and Neointima Formation

Authors: Xiaohan Mei, Xiao-Bing Cui, Yiran Li, Shi-You Chen

Journal: Arterioscler Thromb Vasc Biol

PubMed ID: 34670409

Doi: 10.1161/ATVBAHA.121.316911

Products & Services: Custom Vector Construction

A Novel Variant Associated with Cone Dystrophy Alters cGMP Signaling in Photoreceptors by Strongly Interacting with and Hyperactivating Retinal Guanylate Cyclase

Authors: Amedeo Biasi, Valerio Marino, Giuditta Dal Cortivo, Paolo Enrico Maltese, Antonio Mattia Modarelli, Matteo Bertelli, Leonardo Colombo, Daniele Dell'Orco

Journal: Int J Mol Sci

PubMed ID: 34639157

Doi: 10.3390/ijms221910809

Products & Services: Custom Vector Construction Gene Synthesis

The membrane associated accessory protein is an adeno-associated viral egress factor

Authors: Zachary C Elmore, L Patrick Havlik, Daniel K Oh, Leif Anderson, George Daaboul, Garth W Devlin, Heather A Vincent, Aravind Asokan

Journal: Nat Commun

PubMed ID: 34716331

Doi: 10.1038/s41467-021-26485-4

Products & Services: Custom Vector Construction

Secondary structures, dynamics, and DNA binding of the homeodomain of human SIX1

Authors: Yan Li, Elizabeth YiHui Ng, Ying Ru Loh, Chong Yu Gea, Qiwei Huang, Qingxin Li, CongBao Kang

Journal: J Pept Sci

PubMed ID: 34713534

Doi: 10.1002/psc.3376

Products & Services: Custom Vector Construction

Advances in Universal CAR-T Cell Therapy

Authors: Haolong Lin, Jiali Cheng, Wei Mu, Jianfeng Zhou, Li Zhu

Journal: Front Immunol

PubMed ID: 34691052

Doi: 10.3389/fimmu.2021.744823

Products & Services: CRISPR Libraries

De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories

Authors: Quanli Liu, Yi Liu, Gang Li, Otto Savolainen, Yun Chen, Jens Nielsen

Journal: Nat Commun

PubMed ID: 34667183

Doi: 10.1038/s41467-021-26361-1

Products & Services: Codon Optimization

CRISPR/Cas12a-assisted rapid identification of key beer spoilage bacteria

Authors: Qingzhou Menga, Hongmei Yangb, Guiquan Zhangc, Wenjun Sund, Peixiang Mae, Xinyi Liuf, Lu Dangg, Guanglei Lid, Xingxu Huangd, Xinjie Wangh, Jianghuai Liuc, Qibin Lenga

Journal: Innovative Food Science and Emerging Technologies

Doi: 10.1016/j.ifset.2021.102854

Products & Services: Synthetic sgRNA and crRNA Service

NIN-like protein transcription factors regulate leghemoglobin genes in legume nodules

Authors: Suyu Jiang, Marie-Françoise Jardinaud, Jinpeng Gao, Yann Pecrix, Jiangqi Wen,b Kirankumar Mysore, Ping Xu, Carmen Sanchez-Canizares, Yiting Ruan, Qiujiu Li, Meijun Zhu, Fuyu Li, Ertao Wang, Phillip S Poole, Pascal Gamas, Jeremy D Murray

Journal: Science

PubMed ID: 34709882

Doi: 10.1126/science.abg5945

Products & Services: Gene Synthesis

An improved assay to measure the phospholipid transfer activity of microsomal triglyceride transport protein

Authors: Narasimha Anaganti, Sujith Rajan, M Mahmood Hussain

Journal: J Lipid Res

PubMed ID: 34673018

Doi: 10.1016/j.jlr.2021.100136

Products & Services: Peptide Synthesis

Construction and Analysis of a Yeast for the Simultaneous Release and Esterification of the Varietal Thiol 3-Sulfanylhexan-1-ol

Authors: Florian Kiene, Isak S Pretorius, Doris Rauhut, Christian von Wallbrunn, Niël van Wyk

Journal: J Agric Food Chem

PubMed ID: 34609136

Doi: 10.1021/acs.jafc.1c03976

Products & Services: Synthetic sgRNA and crRNA Service

Dual-antigen targeted iPSC-derived chimeric antigen receptor-T cell therapy for refractory lymphoma

Authors: Sakiko Harada, Miki Ando, Jun Ando, Midori Ishii, Tomoyuki Yamaguchi, Satoshi Yamazaki, Tokuko Toyota, Kazuo Ohara, Manami Ohtaka, Mahito Nakanishi, Chansu Shin, Yasunori Ota, Kazutaka Nakashima, Koichi Ohshima, Chihaya Imai, Yozo Nakazawa, Hiromitsu Nakauchi, Norio Komatsu

Journal: Mol Ther

PubMed ID: 34628050

Doi: 10.1016/j.ymthe.2021.10.006

Products & Services: Recombinant Antibody Expression

TNF-Mediated Inhibition of Classical Swine Fever Virus Replication Is IRF1-, NF-κB- and JAK/STAT Signaling-Dependent

Authors: Matthias Liniger, Markus Gerber, Sandra Renzullo, Obdulio García-Nicolás, Nicolas Ruggli

Journal: Viruses

PubMed ID: 34696447

Doi: 10.3390/v13102017

Products & Services: Proteins, Expression, Isolation and Analysis

Corrigendum to "Rapid preparation of nanodiscs for biophysical studies" [Arch Biochem Biophys 712 (2021) 109051]

Authors: Jeffrey A Julien, Martin G Fernandez, Katrina M Brandmier, Joshua T Del Mundo, Carol M Bator, Lucie A Loftus, Esther W Gomez, Enrique D Gomez, Kerney Jebrell Glover

Journal: Arch Biochem Biophys

PubMed ID: 34756727

Doi: 10.1016/j.abb.2021.109073

Products & Services: Proteins, Expression, Isolation and Analysis

Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family

Authors: Huimin Zhang, Jixiao He, Guang Hu, Fei Zhu, Hao Jiang, Jing Gao, Hu Zhou, Hua Lin, Yingjuan Wang, Kaixian Chen, Fanwang Meng, Minghong Hao, Kehao Zhao, Cheng Luo, Zhongjie Liang

Journal: J Med Chem

PubMed ID: 34668699

Doi: 10.1021/acs.jmedchem.1c01076

Products & Services: Proteins, Expression, Isolation and Analysis

Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates

Authors: Shuang-Zhou Peng, Xiao-Hui Chen, Si-Jie Chen, Jie Zhang, Chuan-Ying Wang, Wei-Rong Liu, Duo Zhang, Ying Su, Xiao-Kun Zhang

Journal: Nat Commun

PubMed ID: 34645818

Doi: 10.1038/s41467-021-26295-8

Products & Services: Proteins, Expression, Isolation and Analysis

Evidence of a shared binding site for Bacillus thuringiensis Cry1Ac and Cry2Aa toxins in Cnaphalocrocis medinalis cadherin

Authors: J Zhong, S Fang, M Gao, L Lu, X Zhang, Q Zhu, Y Liu, J L Jurat-Fuentes, X Liu

Journal: Insect Mol Biol

PubMed ID: 34637177

Doi: 10.1111/imb.12741

Products & Services: Proteins, Expression, Isolation and Analysis

Biomaterial-enabled induction of pancreatic-specific regulatory T cells through distinct signal transduction pathways

Authors: Sean T Carey, Joshua M Gammon, Christopher M Jewell

Journal: Drug Deliv Transl Res

PubMed ID: 34611846

Doi: 10.1007/s13346-021-01075-5

Products & Services: Proteins, Expression, Isolation and Analysis

Enemy of My Enemy: A Novel Insect-Specific Flavivirus Offers a Promising Platform for a Zika Virus Vaccine

Authors: Danielle L Porier, Sarah N Wilson, Dawn I Auguste, Andrew Leber, Sheryl Coutermarsh-Ott, Irving C Allen, Clayton C Caswell, James A Budnick, Josep Bassaganya-Riera, Raquel Hontecillas, James Weger-Lucarelli, Scott C Weaver, Albert J Auguste

Journal: Vaccines (Basel)

PubMed ID: 34696250

Doi: 10.3390/vaccines9101142

Products & Services: Plasmid DNA Preparation

L-asparaginase from : expression, purification and cytotoxicity assessment

Authors: Hesham Saeed, Eman Elsawy, Manal Shalaby, Manal Abdel-Fattah, Asmaa Hemida, Ahmad Eldoksh, Farid Shokry Ataya, Hesham Nematalla, Mohamed Elkewedi, Nikolaos N Labrou, Nefertiti El-Nikhely

Journal: Prep Biochem Biotechnol

PubMed ID: 34612174

Doi: 10.1080/10826068.2021.1983831

Products & Services: Peptide Tools

Bio-inspired green light crosslinked alginate-heparin hydrogels support HUVEC tube formation

Authors: Patrick N Charron, Luis M Garcia, Irfan Tahir, Rachael A Floreani

Journal: J Mech Behav Biomed Mater

PubMed ID: 34736027

Doi: 10.1016/j.jmbbm.2021.104932

Products & Services: Peptide Synthesis

A Novel Antimicrobial Peptide Sparamosin From the Mud Crab Showing Potent Antifungal Activity Against

Authors: Yan-Chao Chen, Ying Yang, Chang Zhang, Hui-Yun Chen, Fangyi Chen, Ke-Jian Wang

Journal: Front Microbiol

PubMed ID: 34690992

Doi: 10.3389/fmicb.2021.746006

Products & Services: Peptide Synthesis

Potent, Selective CARs as Potential T-Cell Therapeutics for HPV-positive Cancers

Authors: Xueyin Wang, Mark L Sandberg, Aaron D Martin, Kathleen R Negri, Grant B Gabrelow, Daniel P Nampe, Ming-Lun Wu, Michele E McElvain, Dora Toledo Warshaviak, Wen-Hua Lee, Julyun Oh, Mark E Daris, Falene Chai, Christine Yao, James Furney, Craig Pigott, Alexander Kamb, Han Xu

Journal: J Immunother

PubMed ID: 34432728

Doi: 10.1097/CJI.0000000000000386

Products & Services: Peptide Synthesis

Marked Increase in Tumor Transfection with a Truncated Branched Polymer

Authors: Songhui Xu, Jiaxi He, Zuha Imtiyaz, Atul K Agrawal, Martin C Woodle, A James Mixson

Journal: J Gene Med

PubMed ID: 34713552

Doi: 10.1002/jgm.3396

Products & Services: Peptide Synthesis

Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the Cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica

Authors: Matej Milacek, Lenka Bittova, Sarka Tumova, Ondrej Luksan, Robert Hanus, Pavlina Kyjakova, Ales Machara, Ales Marek, Marek Jindra

Journal: Insect Biochem Mol Biol

PubMed ID: 34656795

Doi: 10.1016/j.ibmb.2021.103671

Products & Services: Codon Optimization

Engineering transcriptional regulation in Escherichia coli using an archaeal TetR-family transcription factor

Authors: David Sybers, Amber Joka Bernauw, Diala El Masri, Hassan Ramadan Maklad, Daniel Charlier, Marjan De Mey, Indra Bervoets, Eveline Peeters

Journal: Gene

PubMed ID: 34688814

Doi: 10.1016/j.gene.2021.146010

Products & Services: Codon Optimization

Position-Scanning Peptide Libraries as Particle Immunogens for Improving CD8 T-Cell Responses

Authors: Xuedan He, Shiqi Zhou, Breandan Quinn, Wei-Chiao Huang, Dushyant Jahagirdar, Michael Vega, Joaquin Ortega, Mark D Long, Fumito Ito, Scott I Abrams, Jonathan F Lovell

Journal: Adv Sci (Weinh)

PubMed ID: 34716694

Doi: 10.1002/advs.202103023

Products & Services: Catalog Peptides

Tuning Gene Expression by Phosphate in the Methanogenic Archaeon

Authors: Taiwo S Akinyemi, Nana Shao, Zhe Lyu, Ian J Drake, Yuchen Liu, William B Whitman

Journal: ACS Synth Biol

PubMed ID: 34665610

Doi: 10.1021/acssynbio.1c00322

Products & Services: Bacterial Expression

An Engineered Thermostable Laccase with Great Ability to Decolorize and Detoxify Malachite Green

Authors: Guotao Mao, Kai Wang, Fangyuan Wang, Hao Li, Hongsen Zhang, Hui Xie, Zhimin Wang, Fengqin Wang, Andong Song

Journal: Int J Mol Sci

PubMed ID: 34769185

Doi: 10.3390/ijms222111755

Products & Services: Gene Synthesis

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