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Ewing Sarcoma Related protein 1 recognizes R-loops by binding DNA forks

Authors: Michelle A Lay, Valery F Thompson, Ajibola D Adelakun, Jacob C Schwartz

Journal: biorxiv

PubMed ID: 38293191

Doi: 10.1101/2024.01.20.576463

Products & Services: Molecular Biology Reagents

A novel strategy for an anti-idiotype vaccine: nanobody mimicking neutralization epitope of porcine circovirus type 2

Authors: Yingying Deng, Yamin Sheng, Guixi Zhang, Yani Sun, Lei Wang, Pinpin Ji, Jiahong Zhu, Gang Wang, Baoyuan Liu, En-Min Zhou, Xuehui Cai, Yabin Tu, Julian A Hiscox, James P Stewart, Yang Mu, Qin Zhao

Journal: J Virol

PubMed ID: 38271227

Doi: 10.1128/jvi.01650-23

Products & Services: Proteins, Expression, Isolation and Analysis

Improved detection sensitivity of anti-PRV variant antibodies through preparation of anti-gB and anti-gE monoclonal antibodies and development of blocking ELISAs

Authors: Zhenyang Guo, Hu Xu, Siyu Zhang, Haonan Kang, Chao Li, Qi Sun, Jing Zhao, Jinhao Li, Guohui Zhou, Qian Wang, Lirun Xiang, Yandong Tang, Huairan Liu, Chaoliang Leng, Tongqing An, Xuehui Cai, Zhijun Tian, Hongliang Zhang, Jinmei Peng

Journal: Int J Biol Macromol

PubMed ID: 38219937

Doi: 10.1016/j.ijbiomac.2024.129425

Products & Services: Antibody Modification and Purification Services

ETHYLENE RESPONSE FACTOR 070 inhibits flowering in Pak-choi by indirectly impairing BcLEAFY expression

Authors: Zhanghong Yu , Xiaoshan Chen , Yan Li , Sayyed Hamad Ahmad Shah , Dong Xiao , Jianjun Wang , Xilin Hou , Tongkun Liu , Ying Li

Journal: Plant Physiol .

PubMed ID: 38269601

Doi: 10.1093/plphys/kiae021

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A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways

Authors: Zhibin Zhang , Xi Lin , Ling Wei , Yiran Wu , Lu Xu , Lijie Wu , Xiaohu Wei , Suwen Zhao, Xiangjia Zhu , Fei Xu

Journal: Cell Discov .

PubMed ID: 38182578

Doi: s41421-023-00627-y

Products & Services: Codon Optimization

LL‐37_Renalexin hybrid peptide exhibits antimicrobial activity at lower MICs than its counterpart single peptides

Authors: Julius Kwesi Narh , Nestor G Casillas-Vega , Xristo Zarate

Journal: Appl Microbiol Biotechnol .

PubMed ID: 38229302

Doi: 10.1007/s00253-023-12887-5

Products & Services: Gene Synthesis

High-Yield Expression and Purification of Scygonadin, an Antimicrobial Peptide, Using the Small Metal-Binding Protein SmbP

Authors: Jessica J. Gomez-Lugo 1 , Nestor G. Casillas-Vega , Alma Gomez-Loredo , Isaias Balderas-Renteria and Xristo Zarate

Journal: Microorganisms

Doi: 10.3390/microorganisms12020278

Products & Services: Gene Synthesis

Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain

Authors: Yanqun Wang, Zhaoyong Zhang, Minnan Yang, Xinyi Xiong, Qihong Yan, Lei Cao, Peilan Wei, Yuting Zhang, Lu Zhang, Kexin Lv, Jiantao Chen, Xuesong Liu, Xiaochu Zhao, Juxue Xiao, Shengnan Zhang, Airu Zhu, Mian Gan, Jingjun Zhang, Ruoxi Cai, Jianfen Zhuo, Yanjun Zhang, Haiyue Rao, Bin Qu, Yuanyuan Zhang, Lei Chen, Jun Dai, Linling Cheng, Qingtao Hu, Yaoqing Chen, Huibin Lv, Ray T Y So, Malik Peiris, Jingxian Zhao, Xiaoqing Liu, Chris Ka Pun Mok, Xiangxi Wang, Jincun Zhao

Journal: Cell Rep

PubMed ID: 38175758

Doi: 10.1016/j.celrep.2023.113653

Products & Services: Recombinant Proteins

A conserved protein inhibitor brings under check the activity of RNase E in cyanobacteria

Authors: Su-Juan Liu, Gui-Ming Lin, Yu-Qi Yuan, Wenli Chen, Ju-Yuan Zhang, Cheng-Cai Zhang

Journal: Nucleic Acids Res

PubMed ID: 38000383

Doi: 10.1093/nar/gkad1094

Products & Services: Proteins, Expression, Isolation and Analysis

Human microbiota from drug-naive patients with obsessive-compulsive disorder drives behavioral symptoms and neuroinflammation via succinic acid in mice

Authors: Ying-Dan Zhang, Dong-Dong Shi, Bing-Bing Liao, Yi Li, Sen Zhang, Jian Gao, Liang-Jun Lin, Zhen Wang

Journal: Mol Psychiatry

PubMed ID: 38273106

Doi: 10.1038/s41380-024-02424-9

Products & Services: Proteins, Expression, Isolation and Analysis

Pharmacokinetic Analyses of a Lipid Nanoparticle-Encapsulated mRNA-Encoded Antibody against Rift Valley Fever Virus

Authors: Shuo Wang, Ziling Zhu, Jianmin Li

Journal: Mol Pharm

PubMed ID: 38295278

Doi: 10.1021/acs.molpharmaceut.3c01016

Products & Services: Proteins, Expression, Isolation and Analysis

Transition Metal Ion FRET-Based Probe to Study Cu(II)-Mediated Amyloid- Ligand Binding

Authors: Ri Wu, Despoina Svingou, Jonas B Metternich, Lukas R Benzenberg, Renato Zenobi

Journal: J Am Chem Soc

PubMed ID: 38225538

Doi: 10.1021/jacs.3c11533

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Comparison of mouse models of microbial experience reveals differences in microbial diversity and response to vaccination

Authors: Autumn E Sanders, Henriette Arnesen, Frances K Shepherd, Dira S Putri, Jessica K Fiege, Mark J Pierson, Shanley N Roach, Harald Carlsen, David Masopust, Preben Boysen, Ryan A Langlois

Journal: mSphere

PubMed ID: 38286428

Doi: 10.1128/msphere.00654-23

Products & Services: Recombinant Proteins

Antibody reactive immunomes of and are diverse and defined by conformational antigenic determinants

Authors: Tian Luo, Jignesh G Patel, Xiaofeng Zhang, Jere W McBride

Journal: Front Cell Infect Microbiol

PubMed ID: 38264730

Doi: 10.3389/fcimb.2023.1321291

Products & Services: Catalog Peptides

Recombinantly expressed virus-like particles (VLPs) of canine circovirus for development of an indirect ELISA

Authors: Alison Neef, Babu Kanti Nath, Tridip Das, Daniel Luque, Jade K Forwood, Shane R Raidal, Shubhagata Das

Journal: Vet Res Commun

PubMed ID: 38163840

Doi: 10.1007/s11259-023-10290-z

Products & Services: Gene Synthesis

ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism

Authors: Edrees H Rashan, Abigail K Bartlett, Daven B Khana, Jingying Zhang, Raghav Jain, Andrew J Smith, Zakery N Baker, Taylor Cook, Alana Caldwell, Autumn R Chevalier, Brian F Pfleger, Peng Yuan, Daniel Amador-Noguez, Judith A Simcox, David J Pagliarini

Journal: biorxiv

PubMed ID: 38260250

Doi: 10.1101/2024.01.09.574893

Products & Services: Codon Optimization

A glycoside hydrolase 30 protein BpXynC of Bacillus paralicheniformis NMSW12 recognized as A MAMP triggers plant immunity response

Authors: Chenjie Yu, Xiaoli Liang, Yan Song, Qurban Ali, Xihao Yang, Linli Zhu, Qin Gu, Vladislav Kuptsov, Emilia Kolomiets, Huijun Wu, Xuewen Gao

Journal: Int J Biol Macromol

PubMed ID: 38286384

Doi: 10.1016/j.ijbiomac.2024.129750

Products & Services: Mutant Libraries

Remodelling the inguinal adipose sensory system to switch on the furnace: Electroacupuncture stimulation induces brown adipose thermogenesis

Authors: Mengjiang Lu , Ziwei Yu , Xingyu Yang , Li An , Xinyue Jing , Tiancheng Xu , Mengqian Yuan , Bin Xu , Zhi Yu

Journal: Diabetes Obes Metab .

PubMed ID: 38229447

Doi: 10.1111/dom.15444

Products & Services: Proteins, Expression, Isolation and Analysis

Tomato-made edible COVID-19 vaccine TOMAVAC induces neutralizing IgGs in the blood sera of mice and humans

Authors: Zabardast T Buriev, Shukhrat E Shermatov, Dilshod E Usmanov, Mukhammadjon K Mirzakhmedov, Khurshida A Ubaydullaeva, Venera S Kamburova, Bakhtiyor K Rakhmanov, Mirzakamol S Ayubov, Adkham N Abdullaev

Journal: Front Nutr

PubMed ID: 38260078

Doi: 10.3389/fnut.2023.1275307

Products & Services: Gene Synthesis

GDF15 linked to maternal risk of nausea and vomiting during pregnancy

Authors: M Fejzo # 1, N Rocha Cimino # 2, S M Lockhart # 2, C J Petry # 2, R G Kay 2 3, K Burling 2 4, P Barker 2 4, A L George 3, N Yasara 5, A Premawardhena 6 7, S Gong 8 9, E Cook 8, D Rimmington 2, K Rainbow 2, D J Withers 2, V Cortessis 10, P M Mullin 11, K W MacGibbon 12, E Jin, A Kam, A Campbell , O Polasek , G Tzoneva , F M Gribble , G S H Yeo , B Y H Lam , V Saudek, I A Hughes, K K Ong, J R B Perry , A Sutton Cole , M Baumgarten , P Welsh , N Sattar , G C S Smith , D S Charnock-Jones, A P Coll, C L Meek Mettananda , C Hayward, N Mancuso , S O'Rahilly

Journal: Nature

PubMed ID: 38092039

Doi: 10.1038/s41586-023-06921-9

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Smart lattice light-sheet microscopy for imaging rare and complex cellular events

Authors: Yu Shi , Jimmy S Tabet , Daniel E Milkie , Timothy A Daugird , Chelsea Q Yang , Alex T Ritter , Andrea Giovannucci , Wesley R Legant

Journal: Nat Methods

PubMed ID: 38167656

Doi: 10.1038/s41592-023-02126-0

Products & Services: PCR Cloning and Subcloning

Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice

Authors: Kaili Fu 1, Alvin Ho Kwan Cheung 2, Chi Chun Wong 1, Weixin Liu 1, Yunfei Zhou 1, Feixue Wang 1, Pingmei Huang 1, Kai Yuan 1, Olabisi Oluwabukola Coker 1, Yasi Pan 1, Danyu Chen 1, Nga Man Lam 3, Mengxue Gao 4, Xiang Zhang 1, He Huang 4, Ka Fai To 2, Joseph Jao Yiu Sung 5, Jun Yu

Journal: Cell

PubMed ID: 38295787

Doi: 10.1016/j.cell.2024.01.004

Products & Services: Gene Synthesis

Complement receptor 1 is the human erythrocyte receptor for erythrocyte binding protein

Authors: Seong-Kyun Lee, Cécile Crosnier, Paola Carolina Valenzuela-Leon, Brian L P Dizon, John P Atkinson, Jianbing Mu, Gavin J Wright, Eric Calvo, Karthigayan Gunalan, Louis H Miller

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38261617

Doi: 10.1073/pnas.2316304121

Products & Services: Molecular Biology Reagents

Multidimensional Optimization of for Carotenoid Overproduction

Authors: Jian Fan, Yang Zhang, Wenhao Li, Zhizhen Li, Danli Zhang, Qiwen Mo, Mingfeng Cao, Jifeng Yuan

Journal: Biodes Res

PubMed ID: 38213763

Doi: 10.34133/bdr.0026

Products & Services: PCR Cloning and Subcloning

The Development of a Rabies Virus-Vectored Vaccine against , Targeting BBI39

Authors: Shantel Rios, Bibek Bhattachan, Kruthi Vavilikolanu, Chrysoula Kitsou, Utpal Pal, Matthias J Schnell

Journal: Vaccines (Basel)

PubMed ID: 38250891

Doi: 10.3390/vaccines12010078

Products & Services: Recombinant Proteins

Structural role of K224 in taniborbactam inhibition of NDM-1

Authors: Daisuke Ono, Maria F Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego M Moreno, Alejandro J Vila, Robert A Bonomo

Journal: Antimicrob Agents Chemother

PubMed ID: 38174924

Doi: 10.1128/aac.01332-23

Products & Services: Molecular Biology Reagents

Long chain capsaicin analogues synthetized by CALB-CLEAs show cytotoxicity on glioblastoma cell lines

Authors: Tania Diaz-Vidal, Vicente Paúl Armenta-Pérez, Luis Carlos Rosales-Rivera, Georgina Cristina Basulto-Padilla, Raúl Balam Martínez-Pérez, Juan Carlos Mateos-Díaz, Yanet K Gutiérrez-Mercado, Alejandro A Canales-Aguirre, Jorge A Rodríguez

Journal: Appl Microbiol Biotechnol

PubMed ID: 38217255

Doi: 10.1007/s00253-023-12856-y

Products & Services: Catalog Peptides

Irreversible light-activated SpyLigation mediates split-protein assembly in 4D

Authors: Brizzia G Munoz-Robles, Cole A DeForest

Journal: Nat Protoc

PubMed ID: 38253657

Doi: 10.1038/s41596-023-00938-0

Products & Services: Proteins, Expression, Isolation and Analysis

Endolysin NC5 improves early cloxacillin treatment in a mouse model of Streptococcus uberis mastitis

Authors: Niels Vander Elst, Julie Bellemans, Rob Lavigne, Yves Briers, Evelyne Meyer

Journal: Appl Microbiol Biotechnol

PubMed ID: 38204128

Doi: 10.1007/s00253-023-12820-w

Products & Services: Molecular Biology Reagents

The adc1 knockout with proC overexpression in Synechocystis sp PCC 6803 induces a diversion of acetyl-CoA to produce more polyhydroxybutyrate

Authors: Suthira Utharn, Saowarath Jantaro

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 38218963

Doi: 10.1186/s13068-024-02458-9

Products & Services: Proteins, Expression, Isolation and Analysis

Blocking the E2F transcription factor 1/high-mobility group box 2 pathway enhances the intervention effects of α-santalol on the malignant behaviors of liver cancer cells

Authors: Hui Wang, Min Tang, Erli Pei, Ying Shen, Aili Wang, Moubin Lin

Journal: Int J Biochem Cell Biol

PubMed ID: 38219975

Doi: 10.1016/j.biocel.2024.106516

Products & Services: Proteins, Expression, Isolation and Analysis

Affinity-assisted covalent self-assembly of PduQ-SpyTag and Nox-SpyCatcher to construct multi-enzyme complexes on the surface of magnetic microsphere modified with chelated Ni

Authors: Mianxing Luo, Meng Zhang, Changbiao Chi, Guo Chen

Journal: Int J Biol Macromol

PubMed ID: 38218263

Doi: 10.1016/j.ijbiomac.2024.129365

Products & Services: Gene Synthesis

TMEM219 regulates the transcription factor expression and proliferation of beta cells

Authors: Francesca D'Addio, Emma Assi, Anna Maestroni, Giada Rossi, Vera Usuelli, Adriana Petrazzuolo, Marta Nardini, Cristian Loretelli, Moufida Ben Nasr, Paolo Fiorina

Journal: Front Endocrinol (Lausanne)

PubMed ID: 38318298

Doi: 10.3389/fendo.2024.1306127

Products & Services: ORF cDNA Clones/MolecularCloud

Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity

Authors: Ying Meng, Iredia D Iyamu, Noha A M Ahmed, Rong Huang

Journal: ACS Chem Biol

PubMed ID: 38181447

Doi: 10.1021/acschembio.3c00531

Products & Services: Proteins, Expression, Isolation and Analysis

N-acetyltransferase 10 regulates alphavirus replication via N4- acetylcytidine (ac4C) modification of the lymphocyte antigen six family member E (LY6E) mRNA

Authors: Yamei Dang , Jia Li , Yuchang Li , Yuan Wang , Yajing Zhao , Ningbo Zhao , Wanying Li , Hui Zhang , Chuantao Ye , Hongwei Ma , Liang Zhang , He Liu , Yangchao Dong , Min Yao , Yingfeng Lei , Zhikai Xu , Fanglin Zhang , Wei Ye

Journal: J Virol .

PubMed ID: 38169284

Doi: 10.1128/jvi.01350-23

Products & Services: Polyclonal Antibody Services

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Authors: Gisele Nishiguchi , Lauren G Mascibroda , Sarah M Young , Elizabeth A Caine , Sherif Abdelhamed , Jeffrey J Kooijman , Darcie J Miller , Sourav Das , Kevin McGowan , Anand Mayasundari , Zhe Shi , Juan M Barajas , Ryan Hiltenbrand , Anup Aggarwal , Yunchao Chang , Vibhor Mishra , Shilpa Narina , Melvin Thomas , Allister J Loughran , Ravi Kalathur , Kaiwen Yu , Suiping Zhou , Xusheng Wang , Anthony A High , Junmin Peng , Shondra M Pruett-Miller , Danette L Daniels , Marjeta Urh , Anang A Shelat , Charles G Mullighan , Kristin M Riching , Guido J R Zaman , Marcus Fischer , Jeffery M Klco , Zoran Rankovic

Journal: Nat Commun

PubMed ID: 38228616

Doi: 10.1038/s41467-024-44698-1

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Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

Authors: Ayijiang Yisimayi, Weiliang Song, Jing Wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Sijie Yang, Xiao Niu, Tianhe Xiao, Jing Wang , Lijuan Zhao, Haiyan Sun, Ran An, Na Zhang, Yao Wang, Peng Wang, Lingling Yu, Zhe Lv, Qingqing Gu, Fei Shao, Ronghua Jin, Zhongyang Shen, Xiaoliang Sunney Xie, Youchun Wang, Yunlong Cao

Journal: Nature

PubMed ID: 37993710

Doi: 10.1038/s41586-023-06753-7

Products & Services: Gene Synthesis

Structural basis of Gabija anti-phage defence and viral immune evasion

Authors: Sadie P Antine, Alex G Johnson, Sarah E Mooney, Azita Leavitt, Megan L Mayer, Erez Yirmiya, Gil Amitai, Rotem Sorek, Philip J Kranzusch

Journal: Nature

PubMed ID: 37992757

Doi: 10.1038/s41586-023-06855-2

Products & Services: Gene Synthesis

A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover

Authors: David S Glass 1, Anat Bren 2, Elizabeth Vaisbourd 2, Avi Mayo 2, Uri Alon

Journal: Cell

PubMed ID: 38320549

Doi: 10.1016/j.cell.2024.01.024

Products & Services: Plasmid DNA Preparation

Sirtuin 3 is required for the dexmedetomidine-mediated alleviation of inflammation and oxidative stress in nephritis

Authors: Kai Lu , Xinlong Li , Jie Wu

Journal: Immunity

PubMed ID: 38270316

Doi: 10.1002/iid3.1135

Products & Services: Custom DNA/RNA Oligos

Molecular Atlas of HER2+ Breast Cancer Cells Treated with Endogenous Ligands: Temporal Insights into Mechanisms of Trastuzumab Resistance

Authors: Kavitha Mukund, Jackelyn A Alva-Ornelas, Adam L Maddox, Divya Murali, Darya Veraksa, Andras Saftics, Jerneja Tomsic, David Frankhouser, Meagan Razo, Tijana Jovanovic-Talisman, Victoria L Seewaldt, Shankar Subramaniam

Journal: Cancers (Basel)

PubMed ID: 38339304

Doi: 10.3390/cancers16030553

Products & Services: Recombinant Proteins

Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44

Authors: Emily M Cross, Oriano Marin, Daryl Ariawan, David Aragão, Giorgio Cozza, Enzo Di Iorio, Jade K Forwood, Gualtiero Alvisi

Journal: FEBS Lett

PubMed ID: 38158756

Doi: 10.1002/1873-3468.14797

Products & Services: Molecular Biology Reagents

Myosin Va-dependent Transport of NMDA Receptors in Hippocampal Neurons

Authors: Ru Gong, Linwei Qin, Linlin Chen, Ning Wang, Yifei Bao, Wei Lu

Journal: Neurosci Bull

PubMed ID: 38291290

Doi: 10.1007/s12264-023-01174-y

Products & Services: Proteins, Expression, Isolation and Analysis

Revamped mini-αA-crystallin showed improved skin permeation and therapeutic activity against melittin-induced toxicity

Authors: Tenzin Tender, Rakesh Ravishankar Rahangdale, Madhavan Nampoothiri, Ruchira Raychaudhuri, Srinivas Mutalik, Krishna Sharma, Raghu Chandrashekar H

Journal: Toxicon

PubMed ID: 38211805

Doi: 10.1016/j.toxicon.2024.107611

Products & Services: Gene Synthesis

Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors

Authors: Chih-Wei Chu, Tomislav Čaval, Frederico Alisson-Silva, Akshaya Tankasala, Christina Guerrier, Gregg Czerwieniec, Heinz Läubli, Flavio Schwarz

Journal: Life Sci Alliance

PubMed ID: 38176728

Doi: 10.26508/lsa.202302368

Products & Services: Mutant Libraries

Development of Moloney Murine Leukemia Virus Reverse Transcriptase Fused with Archaeal DNA-binding Protein Sis7a

Authors: Goldyna M Simanjuntak, Azzania Fibriani, Amalia A Fananda, Nicholas Yamahoki

Journal: Recent Pat Biotechnol

PubMed ID: 37016518

Doi: 10.2174/1872208317666230403104302

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IL13Rα2 as a crucial receptor for Chi3l1 in osteoclast differentiation and bone resorption through the MAPK/AKT pathway

Authors: Weifeng Xu, Rui Chao, Xinru Xie, Yi Mao, Xinwei Chen, Xuzhuo Chen, Shanyong Zhang