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页码: 43/1026 每页显示数量

Discovery of GPX4 inhibitors through FP-based high-throughput screening

Authors: Yu Cao, Bin Wu, Ying Xu, Mingchen Wang, Xinyu Wu, Xiaochen Liang, Jin Lin, Zhihai Li, Hua Lin, Cheng Luo, Shijie Chen

Journal: Eur J Med Chem

PubMed ID: 38145603

Doi: 10.1016/j.ejmech.2023.116044

Products & Services: Catalog Peptides

Photosensitizer-singlet oxygen sensor conjugated silica nanoparticles for photodynamic therapy and bioimaging

Authors: Jeladhara Sobhanan, Kenji Ono, Takuya Okamoto, Makoto Sawada, Paul S Weiss, Vasudevanpillai Biju

Journal: Chem Sci

PubMed ID: 38332815

Doi: 10.1039/d3sc03877g

Products & Services: Molecular Biology Reagents

Antibodies to D7L salivary proteins as a new serological tool to estimate human exposure to mosquitoes

Authors: Sophana Chea, Laura Willen, Sreynik Nhek, Piseth Ly, Kristina Tang, James Oristian, Roberto Salas-Carrillo, Aiyana Ponce, Paola Carolina Valenzuela Leon, Dara Kong, Sokna Ly, Ratanak Sath, Chanthap Lon, Rithea Leang, Rekol Huy, Christina Yek, Jesus G Valenzuela, Eric Calvo, Jessica E Manning, Fabiano Oliveira

Journal: medrxiv

PubMed ID: 38318204

Doi: 10.1101/2023.12.22.23300438

Products & Services: Proteins, Expression, Isolation and Analysis

Cell cycle status of male and female gametes during Arabidopsis reproduction

Authors: Yoav Voichek, Bohdana Hurieva, Caroline Michaud, Anna Schmücker, Zaida Vergara, Bénédicte Desvoyes, Crisanto Gutierrez, Viktoria Nizhynska, Benjamin Jaegle, Michael Borg, Frédéric Berger, Magnus Nordborg, Mathieu Ingouff

Journal: Plant Physiol

PubMed ID: 37757882

Doi: 10.1093/plphys/kiad512

Products & Services: Gene Synthesis

Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule

Authors: Yi-Wen Wu, Wei-Chun HuangFu, Tony Eight Lin, Chao-Hsiang Peng, Huang-Ju Tu, Ting-Yi Sung, Tzu-Ying Sung, Shih-Chung Yen, Shiow-Lin Pan, Kai-Cheng Hsu

Journal: Int J Biol Macromol

PubMed ID: 38163507

Doi: 10.1016/j.ijbiomac.2023.129074

Products & Services: ORF cDNA Clones/MolecularCloud

Injectable CNPs/DMP1-loaded self-assembly hydrogel regulating inflammation of dental pulp stem cells for dentin regeneration

Authors: Yue Zhao, Lutong Song, Mengchen Li, Haoran Peng, Xinyi Qiu, Yuyang Li, Bijun Zhu, Chao Liu, Shuangshuang Ren, Leiying Miao

Journal: Mater Today Bio

PubMed ID: 38170028

Doi: 10.1016/j.mtbio.2023.100907

Products & Services: Proteins, Expression, Isolation and Analysis

Interaction between membrane curvature sensitive factors SpoVM and SpoIVA in Bicelle condition

Authors: Jiali Chen, Yifan Wang, Shuru Lin, Quanxiang Yu, Zhengfei Qi, Wenqi Jiang, Qiang Zhao, Qingshan Bill Fu

Journal: Biochem Biophys Res Commun

PubMed ID: 38141557

Doi: 10.1016/j.bbrc.2023.149395

Products & Services: Recombinant Proteins

Molecular characterization and functional analysis of peroxiredoxin 1 (Prx1) from roughskin sculpin (Trachidermus fasciatus)

Authors: Yingying Liu, Haiyan Cong, Caihong Bi, Haidong Zha, Shanshan Yu, Lihua Zhao, Qian Zhu

Journal: Fish Physiol Biochem

PubMed ID: 38103084

Doi: 10.1007/s10695-023-01281-7

Products & Services: Molecular Biology Reagents

Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice

Authors: Zhiping Mi, Jie Ma, Dennis J Zeh, Marie E Rose, Jeremy J Henchir, Hao Liu, Xiecheng Ma, Guodong Cao, C Edward Dixon, Steven H Graham

Journal: Exp Neurol

PubMed ID: 38092186

Doi: 10.1016/j.expneurol.2023.114650

Products & Services: Proteins, Expression, Isolation and Analysis

Use of recombinant malate dehydrogenase (MDH) and superoxide dismutase (SOD) [CuZn] as antigens in indirect ELISA for diagnosis of bovine brucellosis

Authors: Rafaella Silva Andrade, Angélica Rosa Faria, Hélida Monteiro Andrade, Júlio Sílvio de Sousa Bueno Filho, Herman Sander Mansur, Alexandra Ancelmo Piscitelli Mansur, Andrey Pereira Lage, Elaine Maria Seles Dorneles

Journal: J Microbiol Methods

PubMed ID: 38101579

Doi: 10.1016/j.mimet.2023.106874

Products & Services: Recombinant Proteins

Design and Engineering of Light-Induced Base Editors Facilitating Genome Editing with Enhanced Fidelity

Authors: Yangning Sun, Qi Chen, Yanbing Cheng, Xi Wang, Zixin Deng, Fuling Zhou, Yuhui Sun

Journal: Adv Sci (Weinh)

PubMed ID: 38039441

Doi: 10.1002/advs.202305311

Products & Services: Gene Synthesis

Tumor-Reactive CD8+ T Cells Enter a TCF1+PD-1- Dysfunctional State

Authors: Jessica J Roetman, Megan M Erwin, Michael W Rudloff, Natalie R Favret, Carlos R Detrés Román, Minna K I Apostolova, Kristen A Murray, Ting-Fang Lee, Youngmin A Lee, Mary Philip

Journal: Cancer Immunol Res

PubMed ID: 37844197

Doi: 10.1158/2326-6066.CIR-22-0939

Products & Services: Peptide Synthesis

Inhalation of taraxasterol loaded mixed micelles for the treatment of idiopathic pulmonary fibrosis

Authors: Tong Zhang , Chao Sun , Shubin Yang , Zimin Cai , Sifeng Zhu , Wendian Liu , Yun Luan , Cheng Wang

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2023.109248

Products & Services: Recombinant Proteins

Molecular basis of Spns2-facilitated sphingosine-1-phosphate transport

Authors: Bin Pang , Leiye Yu , Tong Li , Haizhan Jiao , Xiaomei Wu , Jinxin Wang , Ruiping He , Yurou Zhang , Juan Wang , Hongli Hu , Wei Dai , Li Chen , Ruobing Ren

Journal: Cell Res .

PubMed ID: 38123824

Doi: 10.1038/s41422-023-00908-x

Products & Services: GenCrispr Cas9 Genome Editing

Discrimination of Disaccharide Isomers of Different Glycosidic Linkages Using a Modified MspA Nanopore

Authors: Shanyu Zhang , Zhenyuan Cao , Pingping Fan , Wen Sun , Yunqi Xiao , Panke Zhang , Yuqin Wang , Shuo Huang

Journal: Angew Chem Int Ed Engl .

PubMed ID: 38116834

Doi: 10.1002/anie.202316766

Products & Services: Gene Synthesis

NITR12+ NK Cells Release Perforin to Mediate IgMhi B Cell Killing in Turbot (Scophthalmus maximus)

Authors: Wei Wang, Ying Wang, Jin Yang, Qin Liu, Yuanxing Zhang, Dahai Yang

Journal: J Immunol

PubMed ID: 37843506

Doi: 10.4049/jimmunol.2300281

Products & Services: Proteins, Expression, Isolation and Analysis

Development of Self-Assembled Protein Nanocage Spatially Functionalized with HA Stalk as a Broadly Cross-Reactive Influenza Vaccine Platform

Authors: Jaeyoung Park, Julie A Champion

Journal: ACS Nano

PubMed ID: 38084728

Doi: 10.1021/acsnano.3c07669

Products & Services: Molecular Biology Reagents

The 4-1BBζ costimulatory domain in chimeric antigen receptors enhances CD8+ T-cell functionality following T-cell receptor stimulation

Authors: Gerard J Chu, Charles G Bailey, Rajini Nagarajah, Sharon M Sagnella, Stephen Adelstein, John E J Rasko

Journal: Cancer Cell Int

PubMed ID: 38105188

Doi: 10.1186/s12935-023-03171-7

Products & Services: Proteins, Expression, Isolation and Analysis

Localization confirms EnApiAP2 protein encoded by as a nuclear protein in

Authors: Weimin Cai, Qianqian Feng, Liyue Wang, Shijie Su, Zhaofeng Hou, Dandan Liu, Xilong Kang, Jinjun Xu, Zhiming Pan, Jianping Tao

Journal: Front Cell Infect Microbiol

PubMed ID: 38116134

Doi: 10.3389/fcimb.2023.1305727

Products & Services: Molecular Biology Reagents

Overexpression of endogenous multi-copper oxidases mcoA and mcoC in Rhodococcus jostii RHA1 enhances lignin bioconversion to 2,4-pyridine-dicarboxylic acid

Authors: Goran M M Rashid, Victoria Sodré, Jia Luo, Timothy D H Bugg

Journal: Biotechnol Bioeng

PubMed ID: 38079064

Doi: 10.1002/bit.28620

Products & Services: Gene Synthesis

A bioengineered anti-VEGF protein with high affinity and high concentration for intravitreal treatment of wet age-related macular degeneration

Authors: Chengnan Huang, Yuelin Wang, Jinliang Huang, Huiqin Liu, Zhidong Chen, Yang Jiang, Youxin Chen, Feng Qian

Journal: Bioeng Transl Med

PubMed ID: 38435828

Doi: 10.1002/btm2.10632

Products & Services: Recombinant Proteins

Pal power: Demonstration of the functional association of the Helicobacter pylori flagellar motor with peptidoglycan-associated lipoprotein (Pal) and its preliminary crystallographic analysis

Authors: Xiaotian Zhou, Mohammad M Rahman, Sharmin Q Bonny, Yue Xin, Nikki Liddelow, Mohammad F Khan, Alexandra Tikhomirova, Jihane Homman-Ludiye, Anna Roujeinikova

Journal: Biosci Trends

PubMed ID: 38072447

Doi: 10.5582/bst.2023.01278

Products & Services: Proteins, Expression, Isolation and Analysis

IP8: A quantitatively minor inositol pyrophosphate signaling molecule that punches above its weight

Authors: Chunfang Gu, Xingyao Li, Guangning Zong, Huanchen Wang, Stephen B Shears

Journal: Adv Biol Regul

PubMed ID: 38064879

Doi: 10.1016/j.jbior.2023.101002

Products & Services: Proteins, Expression, Isolation and Analysis

A new gene family (BAPs) of bracovirus induces apoptosis of host hemocytes

Authors: Ze-Hua Wang, Xi-Qian Ye, Xiao-Tong Wu, Zhi-Zhi Wang, Jian-Hua Huang, Xue-Xin Chen

Journal: Virulence

PubMed ID: 36694288

Doi: 10.1080/21505594.2023.2171691

Products & Services: Peptide Synthesis

Molecular mechanism of CCDC106 regulating the p53-Mdm2/MdmX signaling axis

Authors: Ting Zhou, Zhiqiang Ke, Qianqian Ma, Jiani Xiang, Meng Gao, Yongqi Huang, Xiyao Cheng, Zhengding Su

Journal: Sci Rep

PubMed ID: 38081879

Doi: 10.1038/s41598-023-47808-z

Products & Services: Proteins, Expression, Isolation and Analysis

Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway

Authors: Sheena Vasquez, Melissa D Marquez, Edward J Brignole, Amanda Vo, Sunnie Kong, Christopher Park, Deborah L Perlstein, Catherine L Drennan

Journal: Commun Biol

PubMed ID: 38110506

Doi: 10.1038/s42003-023-05579-3

Products & Services: Molecular Biology Reagents

Conserved Residues at the Mtr4 C-Terminus Coordinate Helicase Activity and Exosome Interactions

Authors: Matthew K Yim, Catherine J Stuart, Markell I Pond, Ambro van Hoof, Sean J Johnson

Journal: Biochemistry

PubMed ID: 38085597

Doi: 10.1021/acs.biochem.3c00401

Products & Services: Gene Synthesis

A Chemical Strategy for the Degradation of the Main Protease of SARS-CoV‐2 in Cells

Authors: Xiaohong Sang, Juan Wang, Jiao Zhou, Yan Xu, Jing An, Arieh Warshel, Ziwei Huang

Journal: J Am Chem Soc

PubMed ID: 38064654

Doi: 10.1021/jacs.3c12678.

Products & Services: Codon Optimization

Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa

Authors: Edgar A Diaz-Miranda, Lauren E Hamilton, Michal Zigo, Lindsey Fallon, M Sofia Ortega, Mayra E Ortiz D'Avila Assumpção, José D Guimarães, Peter Sutovsky

Journal: Reproduction

PubMed ID: 37874784

Doi: 10.1530/REP-23-0305

Products & Services: Catalog Peptides

Covalent PROTAC design method based on a sulfonyl pyridone probe

Authors: Qinhong Luo , Yaqi Wang , Zhanfeng Hou , Huiting Liang , Licheng Tu , Yun Xing , Chuan Wan , Jianbo Liu , Rui Wang , Lizhi Zhu , Wei Han , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li

Journal: Chem Commun (Camb) .

PubMed ID: 38054347

Doi: 10.1039/d3cc05127g

Products & Services: Gene Synthesis

Immunorecognition of Streptococcus mutans secreted proteins protects against caries by limiting tooth adhesion

Authors: Omer Bender, Jessica Khoury, Gal Hirsch, Evgeny Weinberg, Naor Sagy, Shani Buller, Shiri Lapides-Levy, Sigalit Blumer, Daniel Z Bar

Journal: J Dent

PubMed ID: 38101504

Doi: 10.1016/j.jdent.2023.104805

Products & Services: Proteins, Expression, Isolation and Analysis

Reproduction of Varroa destructor depends on well-timed host cell recapping and seasonal patterns

Authors: Martin Gabel, Ricarda Scheiner, Ingolf Steffan-Dewenter, Ralph Büchler

Journal: Sci Rep

PubMed ID: 38110489

Doi: 10.1038/s41598-023-49688-9

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered Antiviral Sensor Targets Infected Mosquitoes

Authors: Elena Dalla Benetta, Adam J López-Denman, Hsing-Han Li, Reem A Masri, Daniel J Brogan, Michelle Bui, Ting Yang, Ming Li, Michael Dunn, Melissa J Klein, Sarah Jackson, Kyle Catalan, Kim R Blasdell, Priscilla Tng, Igor Antoshechkin, Luke S Alphey, Prasad N Paradkar, Omar S Akbari

Journal: CRISPR J

PubMed ID: 38108518

Doi: 10.1089/crispr.2023.0056

Products & Services: Gene Synthesis

Green synthesis of silver nanoparticles by using Allium sativum extract and evaluation of their electrical activities in bio-electrochemical cell

Authors: Md Ohiduzzaman, M N I Khan, K A Khan, Bithi Paul

Journal: Nanotechnology

PubMed ID: 38029451

Doi: 10.1088/1361-6528/ad10e4

Products & Services: Proteins, Expression, Isolation and Analysis

SRSF10 facilitates HCC growth and metastasis by suppressing CD8T cell infiltration and targeting SRSF10 enhances anti-PD-L1 therapy

Authors: Xiangyuan Luo, Zerui Zhang, Siwen Li, Yijun Wang, Mengyu Sun, Dian Hu, Junqing Jiang, Yufei Wang, Xiaoyu Ji, Xiaoping Chen, Bixiang Zhang, Huifang Liang, Yiwei Li, Bifeng Liu, Xiao Xu, Shuai Wang, Shengjun Xu, Yongzhan Nie, Kaichun Wu, Daiming Fan, Danfei Liu, Wenjie Huang, Limin Xia

Journal: Int Immunopharmacol

PubMed ID: 38113691

Doi: 10.1016/j.intimp.2023.111376

Products & Services: Molecular Biology Reagents

Global gene regulatory network underlying miR165a in Arabidopsis shoot apical meristem

Authors: Sonali Sinha, Sudeep Sahadevan, Carolyn Ohno, Hasthi Ram, Marcus G Heisler

Journal: Sci Rep

PubMed ID: 38097643

Doi: 10.1038/s41598-023-49093-2

Products & Services: Molecular Biology Reagents

Characterization of human XPD helicase activity with Single Molecule Magnetic Tweezers

Authors: Chunfeng Mao, Maria Mills

Journal: Biophys J

PubMed ID: 38111195

Doi: 10.1016/j.bpj.2023.12.014

Products & Services: CRISPR Cell Lines

CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cell development

Authors: Young Sun Hwang, Yasunari Seita, M Andrés Blanco, Kotaro Sasaki

Journal: PLoS Genet

PubMed ID: 38091369

Doi: 10.1371/journal.pgen.1011080

Products & Services: Gene Synthesis

Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2

Authors: Xia Rao, Runchu Zhao, Zhou Tong, Shuxin Guo, Weiyu Peng, Kefang Liu, Shihua Li, Lili Wu, Jianyu Tong, Yan Chai, Pu Han, Feiran Wang, Peng Jia, Zhaohui Li, Xin Zhao, Dedong Li, Rong Zhang, Xue Zhang, Weiwei Zou, Weiwei Li, Qihui Wang, George Fu Gao, Yan Wu, Lianpan Dai, Feng Gao

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38109549

Doi: 10.1073/pnas.2314193120

Products & Services: Monoclonal Antibody Services

The 6-Month Antibody Durability of Heterologous Convidecia Plus CoronaVac and Homologous CoronaVac Immunizations in People Aged 18-59 Years and over 60 Years Based on Two Randomized Controlled Trials in China

Authors: Hudachuan Jiang, Pengfei Jin, Xiling Guo, Jiahong Zhu, Xue Wang, Peng Wan, Jingxuan Wan, Jingxian Liu, Jingxin Li, Fengcai Zhu

Journal: Vaccines (Basel)

PubMed ID: 38140219

Doi: 10.3390/vaccines11121815

Products & Services: Monoclonal Antibody Services

Host IPR channels are dispensable for rotavirus Ca signaling but critical for intercellular Ca waves that prime uninfected cells for rapid virus spread

Authors: Jacob L Perry, Francesca J Scribano, John T Gebert, Kristen A Engevik, Jenna M Ellis, Joseph M Hyser

Journal: MBio

PubMed ID: 38112482

Doi: 10.1128/mbio.02145-23

Products & Services: Gene Synthesis

The Raf-like MAPKKKs STY8, STY17, and STY46 negatively regulate Botrytis cinerea resistance by limiting MKK7 protein accumulation in Arabidopsis

Authors: Lijuan Chen, Jiahui Xiao, You Li, Yuxiao Song, Jun Liu, Qi Zhou, Ting Sun, Hong-Bin Wang, Bing Liu

Journal: Plant J

PubMed ID: 38059690

Doi: 10.1111/tpj.16578

Products & Services: Catalog Peptides

Bisphenol A induces non-alcoholic fatty liver disease by promoting the O-GlcNAcylation of NLRP3

Authors: Yonghong Zhang, Shujuan Han, Tian Li, Li Zhu, Feng Wei

Journal: Arch Physiol Biochem

PubMed ID: 38038745

Doi: 10.1080/13813455.2023.2288533

Products & Services: Molecular Biology Reagents

Manganese@Albumin Nanocomplex and Its Assembled Nanowire Activate TLR4-Dependent Signaling Cascades of Macrophages

Authors: Shuodan Huang, Yan Gao, Huiying Li, Ruoran Wang, Xiaomei Zhang, Xiaoyu Wang, Di Huang, Linxuan Zhang, Hélder A Santos, Zhenyu Yin, Bing Xia

Journal: Adv Mater

PubMed ID: 37994277

Doi: 10.1002/adma.202310979

Products & Services: Molecular Biology Reagents

Effect of Nk-lysin peptides on bacterial growth, MIC, antimicrobial resistance, and viral activities

Authors: Haitham A Yacoub, Maged Mostafa Mahmoud, Ahmed M Al-Hejin, Turki S Abujamel, Shams Tabrez, Sherif Abd-Elmaksoud

Journal: Anim Biotechnol

PubMed ID: 38100547

Doi: 10.1080/10495398.2023.2290520

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Propagation of conformational instability in FK506-binding protein FKBP12

Authors: David M LeMaster, Qamar Bashir, Griselda Hernández

Journal: Biochim Biophys Acta Proteins Proteom

PubMed ID: 38142946

Doi: 10.1016/j.bbapap.2023.140990

Products & Services: Proteins, Expression, Isolation and Analysis

Multivalent nanobody-based sandwich enzyme-linked immunosorbent assay for sensitive detection of porcine reproductive and respiratory syndrome virus

Authors: Mingxia Sun, Yue Sun, Yongbo Yang, Man Zhao, Dan Cao, Minmin Zhang, Dasong Xia, Tao Wang, Yanfei Gao, Shanghui Wang, Haiwei Wang, Xuehui Cai, Tongqing An

Journal: Int J Biol Macromol

PubMed ID: 38143067

Doi: 10.1016/j.ijbiomac.2023.128896

Products & Services: Proteins, Expression, Isolation and Analysis

MAT2A inhibition suppresses inflammation in -infected human gingival fibroblasts

Authors: Lishan Jiang, Jingwen Li, Kun Ji, Lang Lei, Houxuan Li

Journal: J Oral Microbiol

PubMed ID: 38130504

Doi: 10.1080/20002297.2023.2292375

Products & Services: Molecular Biology Reagents

ACE2-Fc and DPP4-Fc decoy receptors against SARS-CoV-2 and MERS-CoV variants: a quick therapeutic option for current and future coronaviruses outbreaks

Authors: Mohamed A Alfaleh, Reem M Alsulaiman, Sarah A Almahboub, Leena Nezamuldeen, Ayat Zawawi, Najwa D Aljehani, Muhammad Yasir, Rwaa H Abdulal, Rami Alkhaldi, Assala Helal, Sawsan S Alamri, Jana Malki, Rowa Y Alhabbab, Turki S Abujamel, Nabil A Alhakamy, Aisha Alnami, Abdullah Algaissi, Mazen Hassanain, Anwar M Hashem

Journal: Antib Ther

PubMed ID: 38371953

Doi: 10.1093/abt/tbad030

Products & Services: Codon Optimization

Safinamide alleviates hyperalgesia via inhibiting hyperexcitability of DRG neurons in a mouse model of Parkinson's disease

Authors: Li-Ge Zhang, Jing Cheng, Meng-Qi An, Cheng-Jie Li, Li-Guo Dong, Jian-Min Wang, Chun-Feng Liu, Fen Wang, Cheng-Jie Mao

Journal: Behav Brain Res

PubMed ID: 38042302

Doi: 10.1016/j.bbr.2023.114787

Products & Services: Gene Synthesis

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