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Sirtuin 3-mediated deacetylation of superoxide dismutase 2 ameliorates sodium fluoride-induced mitochondrial dysfunction in porcine oocytes
Authors: Xin-Yue Qi, Jin-Dong Yuan, Zi-Yu Liu, Xi-Qing Jiang, Qi Zhang, Shan-Long Zhang, Lu Zhao, Ling-Yan Ke, Chen-Yuan Zhang, Yan Li, Lu-Yan Zhang, Qian-Qian Xu, Zhong-Hua Liu, Jing-Tao Sun, Jun-Xue Jin
Journal: Sci Total Environ
PubMed ID: 37944611
Doi: 10.1016/j.scitotenv.2023.168306
Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations
Authors: Brittany N Williams, Adam Draper, Patrick F Lang, Tylor R Lewis, Audrey L Smith, Steven J Mayerl, Marie Rougié, Jeremy M Simon, Vadim Y Arshavsky, Scott H Greenwald, David M Gamm, Isabel Pinilla, Benjamin D Philpot
Journal: Hum Mol Genet
PubMed ID: 37975905
Doi: 10.1093/hmg/ddad199
Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19
Authors: Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko
Journal: J Infect Dis
PubMed ID: 37948759
Doi: 10.1093/infdis/jiad446
Regioselective Glycosylation of Polyphenols by Family 1 Glycosyltransferases: Experiments and Simulations
Authors: Ruben M de Boer, Dovydas Vaitkus, Kasper Enemark-Rasmussen, Sören Maschmann, David Teze, Ditte H Welner
Journal: ACS Omega
PubMed ID: 38075805
Doi: 10.1021/acsomega.3c08255
Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease
Authors: Yael Gruper, Anette S B Wolff, Liad Glanz, Frantisek Spoutil, Mihaela Cuida Marthinussen, Adriana Osickova, Yonatan Herzig, Yael Goldfarb, Goretti Aranaz-Novaliches, Jan Dobeš, Noam Kadouri, Osher Ben-Nun, Amit Binyamin, Bar Lavi, Tal Givony, Razi Khalaila, Tom Gome, Tomáš Wald, Blanka Mrazkova, Carmel Sochen, Marine Besnard, Shifra Ben-Dor, Ester Feldmesser, Elisaveta M Orlova, Csaba Hegedűs, István Lampé, Tamás Papp, Szabolcs Felszeghy, Radislav Sedlacek, Esti Davidovich, Noa Tal, Dror S Shouval, Raanan Shamir, Carole Guillonneau, Zsuzsa Szondy, Knut E A Lundin, Radim Osicka, Jan Prochazka, Eystein S Husebye, Jakub Abramson
Journal: Nature
PubMed ID: 37993717
Doi: 10.1038/s41586-023-06776-0
Mechanism of δ Mediated Transcription Activation in Bacillus subtilis: Interaction with α CTD of RNA Polymerase Stabilizes δ and Successively Facilitates the Open Complex Formation
Authors: Aniruddha Tewary, Ranjit Kumar Prajapati, Jayanta Mukhopadhyay
Journal: J Mol Biol
PubMed ID: 37972688
Doi: 10.1016/j.jmb.2023.168366
Ana Castillo Discusses Sexuality, Identity, and Life-Then and Now
Authors: Liliana C Gonzalez, Stacy I Macias
Journal: J Lesbian Stud
PubMed ID: 37791458
Doi: 10.1080/10894160.2023.2250670
Products & Services: Plasmid DNA Preparation   
Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2
Authors: Shengnan Zhu, Qingning Yuan, Xinzhu Li, Xinheng He, Shiyi Shen, Dongxue Wang, Junrui Li, Xi Cheng, Xiaoqun Duan, H Eric Xu, Jia Duan
Journal: Cell Rep
PubMed ID: 37952153
Doi: 10.1016/j.celrep.2023.113406
Products & Services: Catalog Antibody   
Non-canonical MLL1 activity regulates centromeric phase separation and genome stability
Authors: Liang Sha, Zi Yang, Sojin An, Wentao Yang, Sungmin Kim, Hoon Oh, Jing Xu, Jun Yin, He Wang, Heinz-Josef Lenz, Woojin An, Uhn-Soo Cho, Yali Dou
Journal: Nat Cell Biol
PubMed ID: 37945831
Doi: 10.1038/s41556-023-01270-1
Products & Services: Catalog Peptides   
Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19
Authors: Maya F Amjadi, Maxwell H Parker, Ryan R Adyniec, Zihao Zheng, Alex M Robbins, S Janna Bashar, Michael F Denny, Sara S McCoy, Irene M Ong, Miriam A Shelef
Journal: J Autoimmun
PubMed ID: 37956528
Doi: 10.1016/j.jaut.2023.103132
Structural and biophysical properties of a [4Fe4S] ferredoxin-like protein from Synechocystis sp PCC 6803 with a unique two domain structure
Authors: Effie Kisgeropoulos, Vivek S Bharadwaj, Anastasia Ledinina, Carolyn E Lubner, David W Mulder, Sharon L Smolinski, Marko Boehm, Kirstin Gutekunst, Paul W King, Drazenka Svedruzic
Journal: J Inorg Biochem
PubMed ID: 38008043
Doi: 10.1016/j.jinorgbio.2023.112428
Products & Services: DNA Sequencing   
Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy
Authors: Daoyuan Xie , Yaomei Tian , Die Hu , Yuanda Wang , Yuling Yang , Bailing Zhou , Rui Zhang , Zhixiang Ren , Mohan Liu , Jie Xu , Chunyan Dong , Binyan Zhao , Li Yang
Journal: Signal Transduct Target Ther .
PubMed ID: 38016957
Doi: 10.1038/s41392-023-01683-2
An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions
Authors: Cailin E Deal, Angelene F Richards, Tracy Yeung, Max J Maron, Ziqiu Wang, Yen-Ting Lai, Brian R Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J Hsiao, Ivana L Rajlic, Hillary Koch, Michael Kleyman, Mark E Pulse, William J Weiss, Jennifer E Doering, Samantha K Lindberg, Nicholas J Mantis, Andrea Carfi, Obadiah J Plante
Journal: Cell Rep Med
PubMed ID: 37918405
Doi: 10.1016/j.xcrm.2023.101253
Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)
Authors: Cheng-Wei Cheng, Chung-Yi Wu, Szu-Wen Wang, Jia-Yan Chen, Chih-Chuan Kung, Kuo-Shiang Liao, Chi-Huey Wong
Journal: Proc Natl Acad Sci U S A
PubMed ID: 38011546
Doi: 10.1073/pnas.2314392120
Reconstruction of dynamic mammary mini gland in vitro for normal physiology and oncogenesis
Authors: Lei Yuan, Shaofang Xie, Huiru Bai, Xiaoqin Liu, Pei Cai, Jing Lu, Chunhui Wang, Zuobao Lin, Shuying Li, Yajing Guo, Shang Cai
Journal: Nat Methods
PubMed ID: 37919421
Doi: 10.1038/s41592-023-02039-y
Self-Entrapment of Antimicrobial Peptides in Silica Particles for Stable and Effective Antimicrobial Peptide Delivery System
Authors: Mi-Ran Ki, Sung Ho Kim, Tae In Park, Seung Pil Pack
Journal: Int J Mol Sci
PubMed ID: 38003614
Doi: 10.3390/ijms242216423
Products & Services: Peptide Synthesis   
IL-27 regulates NLRP3 inflammasome activation of MDSCs in experimental Sjögren's syndrome
Authors: Xiaoyu Xia, Qiqiang Long, Jie Zha, Tingting Jiang, Junqiao Guo, Bo Jiang, Xiaojing Li, Genhong Yao
Journal: Int Immunol
PubMed ID: 37756640
Doi: 10.1093/intimm/dxad037
Products & Services: Molecular Biology Reagents   
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells
Authors: Jing Cheng, Yutong Wang, Lizheng Yin, Wenzhang Liang, Jing Zhang, Cuiqing Ma, Yu Zhang, Bo Liu, Jiachao Wang, Weiting Zhao, Miao Li, Lin Wei
Journal: MBio
PubMed ID: 37909764
Doi: 10.1128/mbio.01480-23
Products & Services: Molecular Biology Reagents   
Mechanism of actin capping protein recruitment and turnover during clathrin-mediated endocytosis
Authors: Andrew K Lamb, Andres N Fernandez, Abdunaser Eadaim, Katelyn Johnson, Santiago M Di Pietro
Journal: J Cell Biol
PubMed ID: 37966720
Doi: 10.1083/jcb.202306154
Products & Services: Peptide Synthesis   
Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry
Authors: Haofeng Wang, Qi Yang, Xiaoce Liu, Zili Xu, Maolin Shao, Dongxu Li, Yinkai Duan, Jielin Tang, Xianqiang Yu, Yumin Zhang, Aihua Hao, Yajie Wang, Jie Chen, Chenghao Zhu, Luke Guddat, Hongli Chen, Leike Zhang, Xinwen Chen, Biao Jiang, Lei Sun, Zihe Rao, Haitao Yang
Journal: Nat Commun
PubMed ID: 37990007
Doi: 10.1038/s41467-023-42527-5
Products & Services: Gene Synthesis   
Effects of protoscoleces excretory-secretory products of Echinococcus granulosus on hepatocyte growth, function, and glucose metabolism
Authors: Guangyi Luo, Haiwen Li, Qiong Lu, Jiangtao Cao, Hailong Lv, Yufeng Jiang
Journal: Acta Trop
PubMed ID: 37944837
Doi: 10.1016/j.actatropica.2023.107066
Products & Services: Molecular Biology Reagents   
Antagonistic conflict between transposon-encoded introns and guide RNAs
Authors: Rimantė Žedaveinytė, Chance Meers, Hoang C Le, Edan E Mortman, Stephen Tang, George D Lampe, Sanjana R Pesari, Diego R Gelsinger, Tanner Wiegand, Samuel H Sternberg
Journal: biorxiv
PubMed ID: 38045383
Doi: 10.1101/2023.11.20.567912
Products & Services: Molecular Biology Reagents   
Acidic pH or salt treatment can convert soluble antibody aggregates in culture harvest into monomers and improve Protein A chromatography step yield
Authors: Ting Zhang, Bin Li, Wanyuan Dong, Yan Wan, Yifeng Li
Journal: Protein Expr Purif
PubMed ID: 37939750
Doi: 10.1016/j.pep.2023.106391
Cardiac myosin-binding protein C N-terminal interactions with myosin and actin filaments: Opposite effects of phosphorylation and M-domain mutations
Authors: Fiona L Wong, Thomas A Bunch, Victoria C Lepak, Allison L Steedman, Brett A Colson
Journal: J Mol Cell Cardiol
PubMed ID: 38008210
Doi: 10.1016/j.yjmcc.2023.11.010
Products & Services: Molecular Biology Reagents   
ZNF70 regulates IL-1β secretion of macrophages to promote the proliferation of HCT116 cells via activation of NLRP3 inflammasome and STAT3 pathway in colitis-associated colorectal cancer
Authors: Zhihong Zhang, Mingyue Li, Yi Tai, Yue Xing, Hongxiang Zuo, Xuejun Jin, Juan Ma
Journal: Cell Signal
PubMed ID: 38000525
Doi: 10.1016/j.cellsig.2023.110979
Products & Services: Molecular Biology Reagents   
A Subunit Vaccine Candidate Composed of Mpox Virus A29L, M1R, A35R, and B6R Elicits Robust Immune Response in Mice
Authors: Xuetao Yang , Xidan Yang , Shouwen Du , Congxia Hu , Xiu Yang , Xingyun Wang , Xing Hu , Nino Rcheulishvili , Peng George Wang and Jihui Lin
Journal: Vaccines.
Doi: 10.3390/vaccines11091420
Products & Services: Gene Synthesis   
Functional Characterization of Novel Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar
Authors: Idris Mohammed, Senthil Selvaraj, Wesam S Ahmed, Tara Al-Barazenji, Ayat S Hammad, Hajar Dauleh, Luis R Saraiva, Mashael Al-Shafai, Khalid Hussain
Journal: Int J Mol Sci
PubMed ID: 38003551
Doi: 10.3390/ijms242216361
Galectin-14 promotes hepatocellular carcinoma tumor growth enhancing heparan sulfate proteoglycan modification
Authors: Liming Gou, Gang Yang, Sujuan Ma, Tong Ding, Luan Sun, Fang Liu, Jin Huang, Wei Gao
Journal: J Biomed Res
PubMed ID: 37977559
Doi: 10.7555/JBR.37.20230085
EBF2 Links KMT2D-Mediated H3K4me1 to Suppress Pancreatic Cancer Progression via Upregulating KLLN
Authors: Bing Yao, Mengying Xing, Shixin Meng, Shang Li, Jingwan Zhou, Ming Zhang, Chen Yang, Shuang Qu, Yucui Jin, Hongyan Yuan, Ke Zen, Changyan Ma
Journal: Adv Sci (Weinh)
PubMed ID: 38015024
Doi: 10.1002/advs.202302037
Products & Services: Peptide Synthesis   
A nanoparticle vaccine displaying the ookinete PSOP25 antigen elicits transmission-blocking antibody response against Plasmodium berghei
Authors: Guixiang Yao, Hui Min, Xinxin Yu, Fei Liu, Liwang Cui, Yaming Cao
Journal: Parasit Vectors
PubMed ID: 37932796
Doi: 10.1186/s13071-023-06020-8
Suburban Population of Bobcats (Lynx rufus) in Connecticut, USA, Tested Negative for SARS-CoV-2, November 2021-February 2022
Authors: Maureen Sims, Zeinab Helal, Milton Levin, Tracy Rittenhouse, Jason Hawley, Guillermo R Risatti
Journal: J Wildl Dis
PubMed ID: 37924242
Doi: 10.7589/JWD-D-23-00054
Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective against Omicron
Authors: Daniela Bottero, Erika Rudi, Pablo Martin Aispuro, Eugenia Zurita, Emilia Gaillard, Maria M Gonzalez Lopez Ledesma, Juan Malito, Matthew Stuible, Nicolas Ambrosis, Yves Durocher, Andrea V Gamarnik, Andrés Wigdorovitz, Daniela Hozbor
Journal: Front Immunol
PubMed ID: 38022542
Doi: 10.3389/fimmu.2023.1271209
Dynamics of Serum-Neutralizing Antibody Responses in Vaccinees through Multiple Doses of the BNT162b2 Vaccine
Authors: Jared Sheehan, Caleb M Ardizzone, Mayank Khanna, Amber J Trauth, Michael E Hagensee, Alistair J Ramsay
Journal: Vaccines (Basel)
PubMed ID: 38006052
Doi: 10.3390/vaccines11111720
Products & Services: Gene Synthesis   
Enhancing the Physicochemical Attributes of Dough and Noodles through the Incorporation of Laccase
Authors: Xiaoyu Zhu, Shijin Zhang, Luyao Bian, Juan Shen, Chong Zhang, Sivakumar Manickam, Yang Tao, Zhaoxin Lu
Journal: Foods
PubMed ID: 38002203
Doi: 10.3390/foods12224146
Cytoplasmic production of Fabs in chemically defined media in fed-batch fermentation
Authors: Angel Castillo-Corujo, Mirva J Saaranen, Lloyd W Ruddock
Journal: Protein Expr Purif
PubMed ID: 37979630
Doi: 10.1016/j.pep.2023.106404
Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets
Authors: Qing Tang, Sebastian Sensale, Charles Bond, Jiazheng Xing, Andy Qiao, Siewert Hugelier, Arian Arab, Gaurav Arya, Melike Lakadamyali
Journal: Curr Biol
PubMed ID: 37979580
Doi: 10.1016/j.cub.2023.10.068
Products & Services: Monoclonal Antibody Services   
DNA Condensation by Peptide-Conjugated PAMAM Dendrimers Influence of Peptide Charge
Authors: Corinna Dannert, Ingrid Mardal, Rahmi Lale, Bjørn Torger Stokke, Rita S Dias
Journal: ACS Omega
PubMed ID: 38046290
Doi: 10.1021/acsomega.3c05140
Products & Services: Peptide Synthesis   
Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid
Authors: Sílvia Àvila-Cabré, Míriam Pérez-Trujillo, Joan Albiol, Pau Ferrer
Journal: Microb Cell Fact
PubMed ID: 37978380
Doi: 10.1186/s12934-023-02241-9
Comparison of biliary protein spectrum in gallstone patients with obesity and those with normal body weight
Authors: Min-Zhi Chen, Ping Xie, Xiao-Chang Wu, Zhen-Hua Tan, Hai Qian, Zhi-Hong Ma, Xing Yao
Journal: Hepatobiliary Pancreat Dis Int
PubMed ID: 38040523
Doi: 10.1016/j.hbpd.2023.11.007
Products & Services: Protein Tools   
Fluorescence-quenching lateral flow immunoassay for “turn-on” and sensitive detection of anti-SARS-CoV-2 neutralizing antibodies in human serum
Authors: Lun Bian , Qiangqiang Fu , Zhuoheng Gan , Ze Wu , Yuchen Song , Yufeng Xiong , Fang Hu, Lei Zheng
Journal: Adv Sci (Weinh) .
PubMed ID: 38032112
Doi: 10.1002/advs.202305774
Products & Services: Recombinant Proteins   
Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding
Authors: Zhi Li , Ning Wu , Jing Wang , Yang Yue , Lihua Geng , Quanbin Zhang
Journal: Br J Pharmacol .
PubMed ID: 37994102
Doi: 10.1111/bph.16288
Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors
Authors: Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, Ilaria Fregno, Timothy Jan Bergmann, Ana Ruano, Aida Delgado, Sara Morales, Xavier Barril, Manolo Bellotto, Elena Cubero, Ana María García-Collazo, Natalia Pérez-Carmona, Maurizio Molinari
Journal: PLoS ONE
PubMed ID: 38019733
Doi: 10.1371/journal.pone.0294437
Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance
Authors: Yanping Yang, Raymond Louie, Janusz Puc, Yogindra Vedvyas, Yago Alcaina, Irene M Min, Matt Britz, Fabio Luciani, Moonsoo M Jin
Journal: Cancers (Basel)
PubMed ID: 38067255
Doi: 10.3390/cancers15235552
Regulation of Atg8 membrane deconjugation by cysteine proteases in the malaria parasite Plasmodium berghei
Authors: Akancha Mishra, Aastha Varshney, Satish Mishra
Journal: Cell Mol Life Sci
PubMed ID: 37910326
Doi: 10.1007/s00018-023-05004-2
Products & Services: Peptide Synthesis   
Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
Authors: Lei Tao, Yue Zhou, Xiangyu Pan, Yuan Luo, Jiahao Qiu, Xia Zhou, Zhiqian Chen, Yan Li, Lian Xu, Yang Zhou, Zeping Zuo, Chunqi Liu, Liang Wang, Xiaocong Liu, Xinyu Tian, Na Su, Zhengnan Yang, Yu Zhang, Kun Gou, Na Sang, Huan Liu, Jiao Zou, Yuzhou Xiao, Xi Zhong, Jing Xu, Xinyu Yang, Kai Xiao, Yanyang Liu, Shengyong Yang, Yong Peng, Junhong Han, Xiaobo Cen, Yinglan Zhao
Journal: Nat Commun
PubMed ID: 37973845
Doi: 10.1038/s41467-023-42850-x
Products & Services: Molecular Biology Reagents   
Molecular Analysis of a Congenital Myasthenic Syndrome Due to a Pathogenic Variant Affecting the C-Terminus of ColQ
Authors: Susie Barbeau, Fannie Semprez, Alexandre Dobbertin, Laurine Merriadec, Florine Roussange, Bruno Eymard, Damien Sternberg, Emmanuel Fournier, Hanice Karasoy, Cécile Martinat, Claire Legay
Journal: Int J Mol Sci
PubMed ID: 38003406
Doi: 10.3390/ijms242216217
Products & Services: Gene Synthesis   
Author Correction: A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques
Authors: Ting Bian, Meng Hao, Xiaofan Zhao, Chuanyi Zhao, Gang Luo, Zhendong Zhang, Guangcheng Fu, Lu Yang, Yi Chen, Yudong Wang, Changming Yu, Yilong Yang, Jianmin Li, Wei Chen
Journal: npj Vaccines
PubMed ID: 38017028
Doi: 10.1038/s41541-023-00780-1
Inflammation primes the kidney for recovery by activating AZIN1 A-to-I editing
Authors: Segewkal Heruye, Jered Myslinski, Chao Zeng, Amy Zollman, Shinichi Makino, Azuma Nanamatsu, Quoseena Mir, Sarath Chandra Janga, Emma H Doud, Michael T Eadon, Bernhard Maier, Michiaki Hamada, Tuan M Tran, Pierre C Dagher, Takashi Hato
Journal: biorxiv
PubMed ID: 37986799
Doi: 10.1101/2023.11.09.566426
Products & Services: Gene Synthesis   
Dual function of Zika virus NS2B-NS3 protease
Authors: Sergey A Shiryaev, Piotr Cieplak, Anton Cheltsov, Robert C Liddington, Alexey V Terskikh
Journal: PLoS Pathog
PubMed ID: 38011215
Doi: 10.1371/journal.ppat.1011795
Products & Services: Custom RNAi Services   
The HIV-1 capsid serves as a nanoscale reaction vessel for reverse transcription
Authors: Jordan Jennings, Harrison Bracey, Danny T Nguyen, Rishav Dasgupta, Alondra Vázquez Rivera, Nicolas Sluis-Cremer, Jiong Shi, Christopher Aiken
Journal: biorxiv
PubMed ID: 37986899
Doi: 10.1101/2023.11.08.566350

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