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Conformational investigation of the asymmetric periplasmic domains of LptBFGC using SDSL CW EPR spectroscopy
Authors: Nicholas P Cina, Candice S Klug
Journal: Appl Magn Reson
PubMed ID: 38645307
Doi: 10.1007/s00723-023-01590-3
Products & Services: Gene Synthesis   
A non-toxic recombinant Clostridium septicum α toxin induces protective immunity in mice and rabbits
Authors: Jige Du, Irene Meki, Qianlin Li, Ying Liu, Zhen Zhu, Chenfan Pan, Yingju Xia, Lizhi Fu, Liu Yang, Suhui Zhang, Chunsheng Yin, Yufeng Luo, Tuanjie Wang, Bo Liu, Xiaoyun Chen
Journal: Toxicon
PubMed ID: 37543293
Doi: 10.1016/j.toxicon.2023.107234
Directed evolution of TetR for constructing sensitive and broad-spectrum tetracycline antibiotics whole-cell biosensor
Authors: Shunlan Li, Dongdong Chen, Ziqing Liu, Shipin Tao, Tianyi Zhang, Yiwen Chen, Lingzhi Bao, Jie Ma, Yuee Huang, Shengmin Xu, Lijun Wu, Shaopeng Chen
Journal: J Hazard Mater
PubMed ID: 37633019
Doi: 10.1016/j.jhazmat.2023.132311
SARS-CoV-2 neutralizing antibody bebtelovimab - a systematic scoping review and meta-analysis
Authors: Mabel Nyit Yi Liew, Kok Pim Kua, Shaun Wen Huey Lee, Kon Ken Wong
Journal: Front Immunol
PubMed ID: 37701439
Doi: 10.3389/fimmu.2023.1100263
Products & Services: Molecular Biology Reagents   
Identification of potential SLA-I-specific T-cell epitopes within the structural proteins of porcine deltacoronavirus
Authors: Yimin Wen, Rui Chen, Junpeng Yang, Enbo Yu, Weizhe Liu, Yijie Liao, Yiping Wen, Rui Wu, Qin Zhao, Senyan Du, Qigui Yan, Xinfeng Han, Sanjie Cao, Xiaobo Huang
Journal: Int J Biol Macromol
PubMed ID: 37579907
Doi: 10.1016/j.ijbiomac.2023.126327
Products & Services: Molecular Biology Reagents   
Binding and transport of LPS occurs through the coordinated combination of an array of sites across the entire Escherichia coli LPS transport protein LptA
Authors: Kathryn M Schultz, John R Schneider, Matthew A Fischer, Nicholas P Cina, Molly O Riegert, Dara W Frank, Candice S Klug
Journal: Protein Sci
PubMed ID: 37417889
Doi: 10.1002/pro.4724
Products & Services: Gene Synthesis   
Nanoparticles carrying paclitaxel and anti-miR-221 for breast cancer therapy triggered by ultrasound
Authors: Libo Zhang, Zhen Ren, Jinhui Lü, Xinhai Mo, Jie Lin, Ya Li, Wenjing Ma, Pengfei Liu, Yajing Shen, Qian Zhao, Lu Qian, Xiaoxin Cheng, Zuoren Yu, Bo Zhang
Journal: Cell Death Discov
PubMed ID: 37582832
Doi: 10.1038/s41420-023-01594-9
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Precision Genome Engineering in Based on a Broad-Host-Range Vector and CRISPR-Cas9 Technology
Authors: Alex Gussak, Maria Laura Ferrando, Mels Schrama, Peter van Baarlen, Jerry Mark Wells
Journal: ACS Synth Biol
PubMed ID: 37602730
Doi: 10.1021/acssynbio.3c00110
Products & Services: Peptide Synthesis   
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1
Authors: Jun-Qi Luo, Tao-Wei Yang, Jun Wu, Hou-Hua Lai, Li-Bin Zou, Wen-Bin Chen, Xu-Min Zhou, Dao-Jun Lv, Sheng-Ren Cen, Zi-Ning Long, Yi-You Mao, Peng-Xiang Zheng, Xiao-Hong Su, Zhi-Yong Xian, Fang-Peng Shu, Xiang-Ming Mao
Journal: Cell Death Dis
PubMed ID: 37542027
Doi: 10.1038/s41419-023-06007-4
Products & Services: Catalog Antibody   
The SlWRKY6-SlPROPEP-SlPep module confers tomato resistance to Phytophthora infestans
Authors: Ruirui Yang , Jie Liu , Zhicheng Wang , Lei Zhao , Tingting Xue , Jun Meng , Yushi Luan
Journal: Scientia Horticulturae
Doi: 10.1016/j.scienta.2023.112117
Products & Services: Peptide Synthesis   
Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells
Authors: Gladys J Keitany , Benjamin E R Rubin , Meghan E Garrett , Andrea Musa , Jeff Tracy , Yu Liang , Peter Ebert , Amanda J Moore , Jonathan Guan , Erica Eggers , Ninnia Lescano , Ryan Brown , Adria Carbo , Hussein Al-Asadi , Travers Ching , Austin Day , Rebecca Harris , Charles Linkem , Dimitry Popov , Courtney Wilkins , Lianqu Li , Jiao Wang , Chuanxin Liu , Li Chen , Jennifer N Dines , Caroline Atyeo , Galit Alter , Lance Baldo , Anna Sherwood , Bryan Howie , Mark Klinger , Erik Yusko , Harlan S Robins , Sharon Benzeno , Amy E Gilbert
Journal: Cell Chem Biol .
PubMed ID: 37586370
Doi: 10.1016/j.chembiol.2023.07.011
A near-infrared fluorescence-enhancing plasmonic biosensing microarray identifies soluble PD-L1 and ICAM-1 as predictive checkpoint biomarkers for cancer immunotherapy
Authors: Zhijun Lin, Mengyao Liu, Wei Xing, Fenghua Wang, Hongxia Zhang, Xiaoli Wei, Hans Schmitthenner, Xi Xie, Xiaojun Xia, Jiang Yang
Journal: Biosens Bioelectron
PubMed ID: 37683502
Doi: 10.1016/j.bios.2023.115633
The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA1, BA2, and BA5
Authors: Huiping Shuai, Jasper Fuk-Woo Chan, Bingjie Hu, Yue Chai, Chaemin Yoon, Huan Liu, Yuanchen Liu, Jialu Shi, Tianrenzheng Zhu, Jing-Chu Hu, Ye-Fan Hu, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Yang Wang, Jinjin Zhang, Yao Xia, Lin-Lei Chen, Jian-Piao Cai, Anna Jinxia Zhang, Shuofeng Yuan, Jie Zhou, Bao-Zhong Zhang, Jian-Dong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Hin Chu
Journal: EBioMedicine
PubMed ID: 37579626
Doi: 10.1016/j.ebiom.2023.104753
Anti-SARS-CoV-2 Antibody Level Is Associated with a History of COVID-19 Infection and mRNA Vaccination in Patients with Diabetes
Authors: Is Asma'ul Haq Hataul, Nanny Natalia M Soetedjo, Josephine Debora, Marita Restie Tiara, Hofiya Djauhari, Evan Susandi, Bachti Alisjahbana, Rudi Wisaksana, Hikmat Permana
Journal: Vaccines (Basel)
PubMed ID: 37766101
Doi: 10.3390/vaccines11091424
ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies
Authors: Adam S Chervin, Jennifer D Stone, Iwona Konieczna, Kelly M Calabrese, Ningyan Wang, Dipica Haribhai, Feng Dong, Michael K White, Luis E Rodriguez, Gail T Bukofzer, Paul A Ellis, Cormac Cosgrove, Claudie Hecquet, Jerry D Clarin, Joann P Palma, Edward B Reilly
Journal: Mol Cancer Ther
PubMed ID: 37294945
Doi: 10.1158/1535-7163.MCT-22-0770
Products & Services: Peptide Synthesis   
Expression analysis, clinical significance and potential function of PLXNB2 in acute myeloid leukaemia
Authors: Zhibo Guo, Dan Guo, Desheng Kong, Sicheng Bian, Linlin Zhao, Qi Li, Leilei Lin, Jiali Hao, Lili Sun, Yinghua Li
Journal: Mol Biol Rep
PubMed ID: 37632633
Doi: 10.1007/s11033-023-08721-w
Products & Services: Molecular Biology Reagents   
NLRC4 promotes the cGAS-STING signaling pathway by facilitating CBL-mediated K63-linked polyubiquitination of TBK1
Authors: Rongzhao Zhang, Wenxian Yang, Huifang Zhu, Jingbo Zhai, Mengzhou Xue, Chunfu Zheng
Journal: J Med Virol
PubMed ID: 37537877
Doi: 10.1002/jmv.29013
Products & Services: Molecular Biology Reagents   
Biosynthesis of High-Active Hemoproteins by the Efficient Heme-Supply Pichia Pastoris Chassis
Authors: Fei Yu, Xinrui Zhao, Jingwen Zhou, Wei Lu, Jianghua Li, Jian Chen, Guocheng Du
Journal: Adv Sci (Weinh)
PubMed ID: 37649147
Doi: 10.1002/advs.202302826
Products & Services: Molecular Biology Reagents   
Obtaining high yield recombinant Enterococcus faecium nicotinate nucleotide adenylyltransferase for X-ray crystallography and biophysical studies
Authors: Olamide Jeje, Ramesh Pandian, Yasien Sayed, Ikechukwu Achilonu
Journal: Int J Biol Macromol
PubMed ID: 37544558
Doi: 10.1016/j.ijbiomac.2023.126066
Products & Services: Molecular Biology Reagents   
Gene co-option, duplication and divergence of cement proteins underpin the evolution of bioadhesives across barnacle life histories
Authors: Yue Him Wong, Niklas Dreyer, HaoCheng Liu, Yi Lan, Jamie J Chen, Jin Sun, Wei-Peng Zhang, Pei-Yuan Qian, Benny K K Chan
Journal: Mol Ecol
PubMed ID: 37584177
Doi: 10.1111/mec.17084
Correction to: An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for Preliminary Ex Vivo Analysis
Authors: Aregitu Mekuriaw Arega, Ajit Kumar Dhal, Kali Prasad Pattanaik, Sasmita Nayak, Rajani Kanta Mahapatra
Journal: Appl Biochem Biotechnol
PubMed ID: 37552364
Doi: 10.1007/s12010-023-04668-7
Products & Services: Gene Synthesis   
NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis
Authors: Quentin I B Lemaître, Natascha Bartsch, Ian U Kouzel, Henriette Busengdal, Gemma Sian Richards, Patrick R H Steinmetz, Fabian Rentzsch
Journal: Nat Commun
PubMed ID: 37563174
Doi: 10.1038/s41467-023-39789-4
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Role of the CagY antenna projection in Cag type IV secretion system activity
Authors: Sirena C Tran, Mark S McClain, Timothy L Cover
Journal: Infect Immun
PubMed ID: 37638724
Doi: 10.1128/iai.00150-23
Products & Services: Plasmid DNA Preparation   
The brassinosteroid-responsive protein OCTOPUS is a novel regulator of immune signaling
Authors: Kaitlyn N Greenwood, Courtney L King, Isabella Melena, Katherine A Stegemann, Maura Donnelly, Anna Childers, Raegan Mozal, Carina A Collins, Benjamin J Spears
Journal: Plant Direct
PubMed ID: 37638229
Doi: 10.1002/pld3.524
Products & Services: Peptide Synthesis   
SARS-CoV-2 ORF8 accessory protein is a virulence factor
Authors: M Bello-Perez, J Hurtado-Tamayo, A Z Mykytyn, M M Lamers, R Requena-Platek, D Schipper, D Muñoz-Santos, J Ripoll-Gómez, A Esteban, P J Sánchez-Cordón, L Enjuanes, B L Haagmans, I Sola
Journal: MBio
PubMed ID: 37623322
Doi: 10.1128/mbio.00451-23
Products & Services: Stable Cell Lines   
Rapid and ultrasensitive detection of mpox virus using CRISPR/Cas12b-empowered graphene field-effect transistors
Authors: LiWang;ChangXu;ShaohuiZhang ;ShangChen;HaoWang;ZhaojunDuan;OmarA.Al-Hartomy ;SwelmWageh;XiaoshaWen;YiLiu;YiLin;HuijiePu;ZhongjianXie;QuanLiu;HanZhang;DixianLuo
Journal: Applied Physics Reviews
Doi: 10.1063/5.0142494
Products & Services: Gene Synthesis   
Flow-cytometric cell sorting coupled with UV mutagenesis for improving pectin lyase expression
Authors: Ke Fang , Jun Ma , Xinyu Wang, Ziting Xu , Ziyang Zhang , Piwu Li , Ruiming Wang, Junqing Wang, Chuying Sun and Ziyang Dong
Journal: Frontiers in bioengineering and biotechnology
Doi: 10.3389/fbioe.2023.1251342
Products & Services: PCR Cloning and Subcloning   
Backbone-Installed Split Intein-Assisted Ligation for the Chemical Synthesis of Mirror-Image Proteins
Authors: Baochang Zhang, Yupeng Zheng, Guochao Chu, Xiangyu Deng, Tongyue Wang, Weiwei Shi, Yongkang Zhou, Shan Tang , Ji-Shen Zheng , Lei Liu
Journal: Angew Chem Int Ed Engl
PubMed ID: 37357888
Doi: 10.1002/anie.202306270
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Enhancement of β-carotene content in Chlamydomonas reinhardtii by expressing bacterium-driven lycopene β-cyclase
Authors: Danqiong Huang , Chenglong Liu , Mingshan Su , Zhiyong Zeng , Chaogang Wang , Zhangli Hu , Sulin Lou , Hui Li
Journal: Biotechnol Biofuels Bioprod .
PubMed ID: 37573357
Doi: 10.1186/s13068-023-02377-1
Products & Services: Gene Synthesis   
Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing
Authors: Lenong Li, Xubiao Peng, Mansoor Batliwala, Marlene Bouvier
Journal: Nat Commun
PubMed ID: 37596268
Doi: 10.1038/s41467-023-40736-6
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Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation
Authors: Frederic Morales-Paytuví, Alba Fajardo, Carles Ruiz-Mirapeix, James Rae, Francesc Tebar, Marta Bosch, Carlos Enrich, Brett M Collins, Robert G Parton, Albert Pol
Journal: J Cell Biol
PubMed ID: 37526691
Doi: 10.1083/jcb.202204020
Interchangeability of the Assays Used to Assess the Activity of Anti-SARS-CoV-2 Monoclonal Antibodies
Authors: Brady T Hickerson, Alexey M Khalenkov, Tao Xie, David M Frucht, Dorothy E Scott, Natalia A Ilyushina
Journal: Viruses
PubMed ID: 37632039
Doi: 10.3390/v15081698
Variation in microbial feature perception in the Rutaceae family with immune receptor conservation in citrus
Authors: Jessica Trinh, Tianrun Li, Jessica Y Franco, Tania Y Toruño, Danielle M Stevens, Shree P Thapa, Justin Wong, Rebeca Pineda, Emmanuel Ávila de Dios, Tracy L Kahn, Danelle K Seymour, Chandrika Ramadugu, Gitta L Coaker
Journal: Plant Physiol
PubMed ID: 37144828
Doi: 10.1093/plphys/kiad263
Products & Services: Peptide Synthesis   
Id-neoantigen vaccine induces therapeutic CD8 T cells against multiple myeloma: H chain-loss escapees cause FLC MM
Authors: Marita Westhrin, Jana Blazevski, Ana Textor, Pegah Abdollahi, Ramakrishna Prabhu Gopalakrishnan, Linda Thuy Ngo, Peter Olaf Hofgaard, Julia Heinzelbecker, Sonja Bobic, Even Fossum, Heidi Cecilie Larsen Spång, Ranveig Braathen, Bjarne Bogen
Journal: J Immunother Cancer
PubMed ID: 37607769
Doi: 10.1136/jitc-2023-006944
CircRNA-CIRH1A Promotes the Development of Osteosarcoma by Regulating PI3K/AKT and JAK2/STAT3 Signaling Pathways
Authors: Meng Zhang, Xiang Wang, Jianfeng Zhao, Jizhou Yan, Xiaodan He, Danxia Qin, Fang Liang, Kai Tong, Jianjian Wang
Journal: Mol Biotechnol
PubMed ID: 37608076
Doi: 10.1007/s12033-023-00812-0
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Stabilisation of the RirA [4Fe-4S] cluster results in loss of iron-sensing function
Authors: Elizabeth Gray, Melissa Y Y Stewart, Libby Hanwell, Jason C Crack, Rebecca Devine, Clare E M Stevenson, Anne Volbeda, Andrew W B Johnston, Juan C Fontecilla-Camps, Matthew I Hutchings, Jonathan D Todd, Nick E Le Brun
Journal: Chem Sci
PubMed ID: 37736639
Doi: 10.1039/d3sc03020b
Products & Services: Gene Synthesis   
Neutrophil-Mediated Tumor-Targeting Delivery System of Oncolytic Bacteria Combined with ICB for Melanoma Lung Metastasis Therapy
Authors: Lina Liu, Wenjie Xin, Qiang Li, Baolian Huang, Te Yin, Siqi Hua, Chen Yang, Chen Chen, Chao Han, Zichun Hua
Journal: Adv Sci (Weinh)
PubMed ID: 37565362
Doi: 10.1002/advs.202301835
Products & Services: Gene Synthesis   
Soluble SARS-CoV-2 RBD and human ACE2 peptidase domain produced in Drosophila S2 cells show functions evoking virus-cell interface
Authors: Federico Carrión, Florencia Rammauro, Natalia Olivero-Deibe, Martín Fló, María Magdalena Portela, Analía Lima, Rosario Durán, Otto Pritsch, Sergio Bianchi
Journal: Protein Sci
PubMed ID: 37405395
Doi: 10.1002/pro.4721
Products & Services: Gene Synthesis   
Garlic-derived exosome-like nanovesicles as a hepatoprotective agent alleviating acute liver failure by inhibiting CCR2/CCR5 signaling and inflammation
Authors: Xin Zhao, Fang Yin, Luoqin Fu, Yingyu Ma, Luyi Ye, Yilin Huang, Weijiao Fan, Wenxue Gao, Yu Cai, Xiaozhou Mou
Journal: Biomater Adv
PubMed ID: 37717364
Doi: 10.1016/j.bioadv.2023.213592
Products & Services: PCR Cloning and Subcloning   
Subtilisin 3 production from Microsporum canis is independent of keratin substrate availability
Authors: Alex E Moskaluk, Lauren Darlington, Sue VandeWoude
Journal: J Basic Microbiol
PubMed ID: 37551993
Doi: 10.1002/jobm.202300125
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
Authors: Robbert J de Haas, Natalie Brunette, Alex Goodson, Justas Dauparas, Sue Y Yi, Erin C Yang, Quinton Dowling, Hannah Nguyen, Alex Kang, Asim K Bera, Banumathi Sankaran, Renko de Vries, David Baker, Neil P King
Journal: biorxiv
PubMed ID: 37577478
Doi: 10.1101/2023.08.04.551935
Products & Services: Molecular Biology Reagents   
Structure of Orthoreovirus RNA Chaperone σNS, a Component of Viral Replication Factories
Authors: Boyang Zhao, Liya Hu, Soni Kuandal, Neetu Neetu, Christopher Lee, Xayathed Somoulay, Banumathi Sankaran, Gwen M Taylor, Terence S Dermody, B V Venkataram Prasad
Journal: biorxiv
PubMed ID: 37577609
Doi: 10.1101/2023.07.31.551319
Non-IgE-reactive allergen peptides deteriorate the skin barrier in house dust mite-sensitized atopic dermatitis patients
Authors: Karin Pfisterer, Matthias Wielscher, David Samardzic, Pauline Weinzettl, Dorte Symmank, Lisa E Shaw, Raffaela Campana, Huey-Jy Huang, Matthias Farlik, Christine Bangert, Susanne Vrtala, Rudolf Valenta, Wolfgang Weninger
Journal: Front Cell Dev Biol
PubMed ID: 37675143
Doi: 10.3389/fcell.2023.1240289
Products & Services: Molecular Biology Reagents   
Mining and Characterization of Indolethylamine N‑Methyltransferases in Amphibian Toad Bufo gargarizans
Authors: An-An Zhang , Qing-Li He , Qunfei Zhao
Journal: Biochemistry .
PubMed ID: 37490721
Doi: 10.1021/acs.biochem.3c00229
Products & Services: Codon Optimization   
Mass-produced gram-negative bacterial outer membrane vesicles activate cancer antigen-specific stem-like CD8 T cells which enables an effective combination immunotherapy with anti-PD-1
Authors: Solchan Won, Changjin Lee, Seoyoon Bae, Jaemin Lee, Dongsic Choi, Min-Gang Kim, Sunghyun Song, Jaewook Lee, Eunhye Kim, HaYoung Shin, Anita Basukala, Tae Ryong Lee, Dong-Sup Lee, Yong Song Gho
Journal: J Extracell Vesicles
PubMed ID: 37563797
Doi: 10.1002/jev2.12357
Products & Services: Molecular Biology Reagents   
A mechanistic insight for the biosynthesis of N,N-dimethyltryptamine: An ONIOM theoretical approach
Authors: Lucas Pinheiro Coutinho, Sérgio Ruschi Bergamachi Silva, Pedro de Lima-Neto, Norberto de Kássio Vieira Monteiro
Journal: Biochem Biophys Res Commun
PubMed ID: 37640000
Doi: 10.1016/j.bbrc.2023.08.043
Products & Services: PCR Cloning and Subcloning   
Sucrose-induced hyperglycemia dysregulates intestinal zinc metabolism and integrity: risk factors for chronic diseases
Authors: Samuel Blake Mitchell, Yu-Han Hung, Trista Lee Thorn, Jiaqi Zou, Filiz Baser, Sukru Gulec, Celeste Cheung, Tolunay Beker Aydemir
Journal: Front Nutr
PubMed ID: 37637953
Doi: 10.3389/fnut.2023.1220533
Products & Services: Monoclonal Antibody Services   
Structure, catalysis, chitin transport, and selective inhibition of chitin synthase
Authors: Dan-Dan Chen, Zhao-Bin Wang, Le-Xuan Wang, Peng Zhao, Cai-Hong Yun, Lin Bai
Journal: Nat Commun
PubMed ID: 37553334
Doi: 10.1038/s41467-023-40479-4
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Sm-like protein Rof inhibits transcription termination factor ρ by binding site obstruction and conformational insulation
Authors: Nelly Said, Mark Finazzo, Tarek Hilal, Bing Wang, Tim Luca Selinger, Daniela Gjorgjevikj, Irina Artsimovitch, Markus C Wahl
Journal: biorxiv
PubMed ID: 37693585
Doi: 10.1101/2023.08.30.555460
Performance upgrade of a microbial explosives' sensor strain by screening a high throughput saturation library of a transcriptional regulator
Authors: Lidor David, Etai Shpigel, Itay Levin, Shaked Moshe, Lior Zimmerman, Shilat Dadon-Simanowitz, Benjamin Shemer, Shon A Levkovich, Liraz Larush, Shlomo Magdassi, Shimshon Belkin
Journal: Comput Struct Biotechnol J
PubMed ID: 37701016
Doi: 10.1016/j.csbj.2023.08.017

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