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Engineering the HK97 virus-like particle as a nanoplatform for biotechnology applications
Authors: Michael D Woods, Matthew Cali, Bubacarr Ceesay, Shandis Fancher, Gaini Ibrasheva, Suefian Kandeel, Manon Nassar, Ali Azghani, Brent Bill, Dustin P Patterson
Journal: J Mater Chem B
PubMed ID: 37345352
Doi: 10.1039/d3tb00318c
MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice
Authors: Nana Li, Junjie Yu, Meiyang Zhou, Fanyi Qiu, Xiao Wang, Zhengpin Wang
Journal: Biochem Biophys Res Commun
PubMed ID: 37451217
Doi: 10.1016/j.bbrc.2023.07.013
Structural and biochemical characterization of Schlafen11 N-terminal domain
Authors: Pengjiao Hou, Wei Hao, Bo Qin, Mengyun Li, Rong Zhao, Sheng Cui
Journal: Nucleic Acids Res
PubMed ID: 37293979
Doi: 10.1093/nar/gkad509
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An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for Preliminary Ex Vivo Analysis
Authors: Aregitu Mekuriaw Arega, Ajit Kumar Dhal, Kali Prasad Pattanaik, Sasmita Nayak, Rajani Kanta Mahapatra
Journal: Appl Biochem Biotechnol
PubMed ID: 37498378
Doi: 10.1007/s12010-023-04658-9
Products & Services: Gene Synthesis   
A Biosafety Study of Human Umbilical Cord Blood Mononuclear Cells Transduced with Adenoviral Vector Carrying Human Vascular Endothelial Growth Factor cDNA In Vitro
Authors: Ilnur I Salafutdinov , Dilara Z Gatina , Maria I Markelova , Ekaterina E Garanina , Sergey Yu Malanin , Ilnaz M Gazizov , Andrei A Izmailov , Albert A Rizvanov , Rustem R Islamov , András Palotás , Zufar Z Safiullov
Journal: Biomedicines .
PubMed ID: 37509661
Doi: 10.3390/biomedicines11072020
Products & Services: Catalog Antibody   
Actions of a Novel Bacterial Topoisomerase Inhibitor against Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks
Authors: Soziema E Dauda, Jessica A Collins, Jo Ann W Byl, Yanran Lu, Jack C Yalowich, Mark J Mitton-Fry, Neil Osheroff
Journal: Int J Mol Sci
PubMed ID: 37569485
Doi: 10.3390/ijms241512107
Accurate identification and discrimination of serovar Gallinarum biovars Gallinarum and Pullorum by a multiplex PCR based on the new genes of and
Authors: Li Song, Ruimeng Tan, Dan Xiong, Xinan Jiao, Zhiming Pan
Journal: Front Vet Sci
PubMed ID: 37476820
Doi: 10.3389/fvets.2023.1220118
A mass spectrometry assay for detection of endogenous and lentiviral engineered hemoglobin in cultured cells and sickle cell disease mice
Authors: Xuejun Wang, William M McKillop, Theresa A Dlugi, Mary L Faber, Juliana Alvarez-Argote, Christopher B Chambers, Andrew Wilber, Jeffrey A Medin
Journal: J Gene Med
PubMed ID: 37455676
Doi: 10.1002/jgm.3567
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Kinetic and Structural Characterization of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors
Authors: Kayla Glockzin, Kathleen M Meneely, Ryan Hughes, Sean W Maatouk, Grace E Piña, Kajitha Suthagar, Keith Clinch, Joshua N Buckler, Audrey L Lamb, Peter C Tyler, Thomas D Meek, Ardala Katzfuss
Journal: Biochemistry
PubMed ID: 37418678
Doi: 10.1021/acs.biochem.3c00116
Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity
Authors: Ian N Boys, Alex G Johnson, Meghan R Quinlan, Philip J Kranzusch, Nels C Elde
Journal: Cell Rep
PubMed ID: 37494187
Doi: 10.1016/j.celrep.2023.112878
Products & Services: Molecular Biology Reagents   
Computationally Designed Small Molecules Disassemble Both Soluble Oligomers and Protofibrils of Amyloid β-Protein Responsible for Alzheimer's Disease
Authors: Yingying Jin, Matthew A Downey, Ambuj Singh, Steven K Buratto, Michael T Bowers
Journal: ACS Chem Neurosci
PubMed ID: 37442126
Doi: 10.1021/acschemneuro.3c00266
Novel Frizzled-specific antibody-based Wnt mimetics and Wnt superagonists selectively activate WNT/β-catenin signaling in target tissues
Authors: Yorick Post, Archana Dilip, Liqin Xie, Asmiti Sura, Nicholas Suen, Jay Ye, Devin Mutha, Angela T Liu, Huy Nguyen, Elizabeth Whisler, Darshini Shah, Shalaka Deshmukh, Navrose Dhaliwal, Ben Bauer, Eskedar Nigatu, Anh Diep, Tom Lopez, Tristan W Fowler, Sung-Jin Lee, Chenggang Lu, Wen-Chen Yeh, Hui Chen, Yang Li
Journal: Cell Chem Biol
PubMed ID: 37413985
Doi: 10.1016/j.chembiol.2023.06.006
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Role and neural regulation of clock genes in the rat pineal gland: Clock modulates amplitude of rhythmic expression of Aanat encoding the melatonin-producing enzyme
Authors: Aurea S Blancas-Velazquez, Tenna Bering, Signe Bille, Martin F Rath
Journal: J Pineal Res
PubMed ID: 37349875
Doi: 10.1111/jpi.12893
Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor
Authors: Wan Ni Chia, Chee Wah Tan, Aaron Wai Kit Tan, Barnaby Young, Tyler N Starr, Ester Lopez, Guntur Fibriansah, Jennifer Barr, Samuel Cheng, Aileen Ying-Yan Yeoh, Wee Chee Yap, Beng Lee Lim, Thiam-Seng Ng, Wan Rong Sia, Feng Zhu, Shiwei Chen, Jinyan Zhang, Madeline Sheng Si Kwek, Allison J Greaney, Mark Chen, Gough G Au, Prasad N Paradkar, Malik Peiris, Amy W Chung, Jesse D Bloom, David Lye, Sheemei Lok, Lin-Fa Wang
Journal: Sci Adv
PubMed ID: 37494438
Doi: 10.1126/sciadv.ade3470
Breakthrough SARS-CoV-2 Omicron Variant in Individuals Primed with Heterologous Vaccines Enhances Inhibition Performance of Neutralizing Antibody to BA2 Parental Lineage
Authors: Jidapa Szekely, Piyawut Swangphon, Natthaphon Nanakorn, Panuttha Chaimuti, Teerapat Nualnoi, Paweena Wongwitwichot, Namchoke Somapa, Denpong Somapa, Theerakamol Pengsakul
Journal: Vaccines (Basel)
PubMed ID: 37515045
Doi: 10.3390/vaccines11071230
Products & Services: Molecular Biology Reagents   
Development of quantitative multiplex RT-qPCR one step assay for detection of hepatitis delta virus
Authors: Jackson Alves da Silva Queiroz, Tárcio Peixoto Roca, Rutilene Barbosa Souza, Luiz Fellype Alves de Souza, Ana Maísa Passos-Silva, André Luiz Ferreira da Silva, Eugênia de Castro E Silva, Lourdes Maria Pinheiro Borzacov, Rita de Cássia Pontello Rampazzo, Soraya Dos Santos Pereira, Thor Oliveira Dantas, Janaína Mazaro, Lívia Melo Villar, Juan Miguel Villalobos Salcedo, Daniel Archimedes da Matta, Deusilene Vieira
Journal: Sci Rep
PubMed ID: 37495613
Doi: 10.1038/s41598-023-37756-z
Products & Services: Molecular Biology Reagents   
Absolute Quantification of Photoreceptor Outer Segment Proteins
Authors: Nikolai P Skiba, Tylor R Lewis, William J Spencer, Carson M Castillo, Andrej Shevchenko, Vadim Y Arshavsky
Journal: J Proteome Res
PubMed ID: 37493966
Doi: 10.1021/acs.jproteome.3c00267
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Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity
Authors: Benedikt Goretzki, Christoph Wiedemann, Brett A McCray, Stefan L Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K Donohue, Cy M Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J Sumner, Gerhard Hummer, Ute A Hellmich
Journal: Nat Commun
PubMed ID: 37443299
Doi: 10.1038/s41467-023-39808-4
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Structural basis of CXC chemokine receptor 1 ligand binding and activation
Authors: Naito Ishimoto, Jae-Hyun Park, Kouki Kawakami, Michiko Tajiri, Kenji Mizutani, Satoko Akashi, Jeremy R H Tame, Asuka Inoue, Sam-Yong Park
Journal: Nat Commun
PubMed ID: 37433790
Doi: 10.1038/s41467-023-39799-2
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Spatially-Encoding Hydrogels With DNA to Control Cell Signaling
Authors: Namrata Ramani, C Adrian Figg, Alex J Anderson, Peter H Winegar, EunBi Oh, Sasha B Ebrahimi, Devleena Samanta, Chad A Mirkin
Journal: Adv Mater
PubMed ID: 37221642
Doi: 10.1002/adma.202301086
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Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery
Authors: Natalie S Wallace, John E Gadbery, Cameron I Cohen, Amy K Kendall, Lauren P Jackson
Journal: biorxiv
PubMed ID: 37502979
Doi: 10.1101/2023.07.18.549521
Non-canonical function of folate/folate receptor 1 during neural tube formation
Authors: Olga A Balashova, Alexios A Panoutsopoulos, Olesya Visina, Jacob Selhub, Paul S Knoepfler, Laura N Borodinsky
Journal: biorxiv
PubMed ID: 37503108
Doi: 10.1101/2023.07.19.549718
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Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis
Authors: Yi Zhou, Guofei Cui, Hongwei Xu, Joanne Chun, Doris Yang, Zheng Zhang, Lihui Yang, Jingxiao Wang, Meijuan Wan, Diego F Calvisi, Shumei Lin, Xin Chen, Haichuan Wang
Journal: Cell Death Dis
PubMed ID: 37500626
Doi: 10.1038/s41419-023-05958-y
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Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity
Authors: Jaime L Jensen, Rajeshwer S Sankhala, Vincent Dussupt, Hongjun Bai, Agnes Hajduczki, Kerri G Lal, William C Chang, Elizabeth J Martinez, Caroline E Peterson, Emily S Golub, Phyllis A Rees, Letzibeth Mendez-Rivera, Michelle Zemil, Erin Kavusak, Sandra V Mayer, Lindsay Wieczorek, Shruthi Kannan, Benjamin J Doranz, Edgar Davidson, Eun Sung Yang, Yi Zhang, Man Chen, Misook Choe, Lingshu Wang, Gregory D Gromowski, Richard A Koup, Nelson L Michael, Victoria R Polonis, Morgane Rolland, Kayvon Modjarrad, Shelly J Krebs, M Gordon Joyce
Journal: J Virol
PubMed ID: 37395646
Doi: 10.1128/jvi.01596-22
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Phosphorylation of the N-terminus of Syntaxin-16 controls interaction with mVps45 and GLUT4 trafficking in adipocytes
Authors: Shaun K Bremner, Rebecca Berends, Alexandra Kaupisch, Jennifer Roccisana, Calum Sutherland, Nia J Bryant, Gwyn W Gould
Journal: PeerJ
PubMed ID: 37520260
Doi: 10.7717/peerj.15630
A natural gene drive system confers reproductive isolation in rice
Authors: Chaolong Wang, Jian Wang, Jiayu Lu, Yehui Xiong, Zhigang Zhao, Xiaowen Yu, Xiaoming Zheng, Jing Li, Qibing Lin, Yulong Ren, Yang Hu, Xiaodong He, Chao Li, Yonglun Zeng, Rong Miao, Mali Guo, Bosen Zhang, Ying Zhu, Yunhui Zhang, Weijie Tang, Yunlong Wang, Benyuan Hao, Qiming Wang, Siqi Cheng, Xiaojuan He, Bowen Yao, Junwen Gao, Xufei Zhu, Hao Yu, Yong Wang, Yan Sun, Chunlei Zhou, Hui Dong, Xiaoding Ma, Xiuping Guo, Xi Liu, Yunlu Tian, Shijia Liu, Chunming Wang, Zhijun Cheng, Ling Jiang, Jiawu Zhou, Huishan Guo, Liwen Jiang, Dayun Tao, Jijie Chai, Wei Zhang, Haiyang Wang, Chuanyin Wu, Jianmin Wan
Journal: Cell
PubMed ID: 37499659
Doi: 10.1016/j.cell.2023.06.023
Histone deacetylase III interactions with BK polyomavirus large tumor antigen may affect protein stability
Authors: Yueh-Han Hsu, Chun-Nun Chao, Hsin-Yi Huang, Pei-Wen Zhao, Pang-Hung Hsu, Cheng-Huang Shen, San-Yuan Chen, Chiung-Yao Fang
Journal: Virol J
PubMed ID: 37464367
Doi: 10.1186/s12985-023-02128-6
Products & Services: Molecular Biology Reagents   
TP5: A Novel Therapeutic Approach Targeting Aberrant and Hyperactive CDK5/p25 for the Treatment of Colorectal Carcinoma
Authors: Niranjana Amin, Herui Wang, Qi Song, Manju Bhaskar, Sharda Prasad Yadav, Mark R Gilbert, Harish Pant, Emeline Tabouret, Zhengping Zhuang
Journal: Int J Mol Sci
PubMed ID: 37511490
Doi: 10.3390/ijms241411733
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Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS–STING pathway
Authors: Jing An , Chuan-Ping Zhang , Hou-Yuan Qiu , Hong-Xia Zhang , Qiu-Bing Chen , Yu-Ming Zhang , Xin-Lin Lei , Cai-Xiang Zhang , Hao Yin , Ying Zhang
Journal: Nat Biomed Eng .
PubMed ID: 37500747
Doi: 10.1038/s41551-023-01073-7
Products & Services: CRISPR Plasmids   
The combination of osimertinib with Raf inhibitor overcomes osimertinib resistance induced by KRAS amplification in EGFR-mutated lung cancer cells
Authors: Tae-Gul Lee, Hye-Min Kang, Seo Yun Kim, Hye-Ryoun Kim, Cheol Hyeon Kim
Journal: Exp Cell Res
PubMed ID: 37442265
Doi: 10.1016/j.yexcr.2023.113722
Combined Inhibition of the TGF-β1/Smad Pathway by and to Reduce Inflammation and Fibrosis in Primary Sclerosing Cholangitis
Authors: Yu Shen, Baorong Jiang, Chenchen Zhang, Qian Wu, Lei Li, Ping Jiang
Journal: Int J Mol Sci
PubMed ID: 37446187
Doi: 10.3390/ijms241311010
Viral manipulation of cell polarity signalling
Authors: Airah Javorsky, Patrick O Humbert, Marc Kvansakul
Journal: Biochim Biophys Acta Mol Cell Res
PubMed ID: 37437846
Doi: 10.1016/j.bbamcr.2023.119536
Products & Services: Molecular Biology Reagents   
Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis
Authors: Aleksandra W Debowski, Nicole M Bzdyl, David R Thomas, Nichollas E Scott, Christopher H Jenkins, Jua Iwasaki, Emily A Kibble, Chen Ai Khoo, Nicolas J Scheuplein, Pamela M Seibel, Theresa Lohr, Georgie Metters, Charles S Bond, Isobel H Norville, Keith A Stubbs, Nicholas J Harmer, Ulrike Holzgrabe, Hayley J Newton, Mitali Sarkar-Tyson
Journal: PLoS Pathog
PubMed ID: 37399210
Doi: 10.1371/journal.ppat.1011491
Investigating the aggregation perspective of Dengue virus proteome
Authors: Shivani Krishna Kapuganti, Kumar Udit Saumya, Deepanshu Verma, Rajanish Giri
Journal: Virology
PubMed ID: 37473502
Doi: 10.1016/j.virol.2023.07.010
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Notch Intracellular Domains form Transcriptionally Active Heterodimeric Complexes on Sequence-paired Sites
Authors: Tana R Gazdik, Jacob J Crow, Tyler Lawton, Chloe J Munroe, Hannah Theriault, Travis M Wood, Allan R Albig
Journal: Res Sq
PubMed ID: 37546896
Doi: 10.21203/rs.3.rs-3147210/v1
Pathogenic CANVAS (AAGGG) repeats stall DNA replication due to the formation of alternative DNA structures
Authors: Julia A Hisey, Elina A Radchenko, Silvia Ceschi, Anastasia Rastokina, Nicholas H Mandel, Ryan J McGinty, Gabriel Matos-Rodrigues, Alfredo Hernandez, André Nussenzweig, Sergei M Mirkin
Journal: biorxiv
PubMed ID: 37546920
Doi: 10.1101/2023.07.25.550509
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Prokaryotic Gabija complex senses and executes nucleotide depletion and DNA cleavage for antiviral defense
Authors: Rui Cheng , Fengtao Huang , Xueling Lu , Yan Yan , Bingbing Yu , Xionglue Wang , Bin Zhu
Journal: Cell Host Microbe .
PubMed ID: 37480847
Doi: 10.1016/j.chom.2023.06.014
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Targeting CXCR4-expressing Cancer Cells with Avidin-poly (lactic-co-glycolic acid) Nanoparticle Surface Modified with Biotinylated DV1 Peptide
Authors: Shiba Ansari, Madeeha Mudassir, B Vijayalekshmi, Parthaprasad Chattopadhyay
Journal: Int J Appl Basic Med Res
PubMed ID: 37614837
Doi: 10.4103/ijabmr.ijabmr_58_23
Products & Services: Peptide Synthesis   
Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results
Authors: Raffit Hassan, Marcus Butler, Roisin E O'Cearbhaill, David Y Oh, Melissa Johnson, Kevin Zikaras, Munisha Smalley, Michael Ross, Janos L Tanyi, Azam Ghafoor, Nirali N Shah, Babak Saboury, Liang Cao, Alfonso Quintás-Cardama, David Hong
Journal: Nat Med
PubMed ID: 37501016
Doi: 10.1038/s41591-023-02452-y
Monitoring SARS-CoV-2 variants in wastewater of Dhaka City, Bangladesh: approach to complement public health surveillance systems
Authors: Rehnuma Haque, Mohammad Enayet Hossain, Mojnu Miah, Mahbubur Rahman, Nuhu Amin, Ziaur Rahman, Md Shariful Islam, Mohammed Ziaur Rahman
Journal: Hum Genomics
PubMed ID: 37420264
Doi: 10.1186/s40246-023-00505-4
Products & Services: Molecular Biology Reagents   
Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins
Authors: Ashley P Viera Ortiz, Gregory Cajka, Olamide A Olatunji, Bailey Mikytuck, Ophir Shalem, Edward B Lee
Journal: Brain
PubMed ID: 36516294
Doi: 10.1093/brain/awac479
Products & Services: DNA Sequencing   
Oncolytic viruses engineered to enforce cholesterol efflux restore tumor-associated macrophage phagocytosis and anti-tumor immunity in glioblastoma
Authors: Shiqun Wang , Wei Yan, Lingkai Kong , Shuguang Zuo , Jingyi Wu, Chunxiao Zhu , Huaping Huang , Bohao He, Jie Dong, Jiwu Wei
Journal: Nat Commun .
PubMed ID: 37474548
Doi: 10.1038/s41467-023-39683-z
Products & Services: Oligo pool   
Enhanced Carotenoid Production in Chlamydomonas reinhardtii via Overexpression of Endogenous and Exogenous Beta-Carotene Ketolase (BKT) Genes
Authors: Yuanhao Chen , Hong Du , Honghao Liang , Ting Hong , Tangcheng Li
Journal: Int J Mol Sci .
PubMed ID: 37511141
Doi: 1422-0067/24/14/11382
Products & Services: Gene Synthesis   
Perdeuterated GbpA Enables Neutron Scattering Experiments of a Lytic Polysaccharide Monooxygenase
Authors: H V Sørensen, Mateu Montserrat-Canals, Jennifer S M Loose, S Zoë Fisher, Martine Moulin, Matthew P Blakeley, Gabriele Cordara, Kaare Bjerregaard-Andersen, Ute Krengel
Journal: ACS Omega
PubMed ID: 37599915
Doi: 10.1021/acsomega.3c02168
Immunogenicity and safety of inactivated SARS-CoV-2 vaccine in haemodialysis patients: a prospective cohort study
Authors: Metalia Puspitasari, Prenali D Sattwika, Dzerlina S Rahari, Wynne Wijaya, Auliana R P Hidayat, Nyoman Kertia, Bambang Purwanto, Jarir At Thobari
Journal: Sci Rep
PubMed ID: 37463975
Doi: 10.1038/s41598-023-38628-2
Products & Services: Molecular Biology Reagents   
Interspersed expression of CUP-SHAPED COTYLEDON2 and REDUCED COMPLEXITY shapes Cardamine hirsuta complex leaf form
Authors: Neha Bhatia, David Wilson-Sánchez, Sören Strauss, Francesco Vuolo, Bjorn Pieper, Ziliang Hu, Léa Rambaud-Lavigne, Miltos Tsiantis
Journal: Curr Biol
PubMed ID: 37453425
Doi: 10.1016/j.cub.2023.06.037
Products & Services: Molecular Biology Reagents   
A deep learning-based drug repurposing screening and validation for anti-SARS-CoV-2 compounds by targeting the cell entry mechanism
Authors: Yingjia Yao, Yunhan Zhang, Zexu Li, Zhisong Chen, Xiaofeng Wang, Zihan Li, Li Yu, Xiaolong Cheng, Wei Li, Wen-Jie Jiang, Hua-Jun Wu, Zezhong Feng, Jinfu Sun, Teng Fei
Journal: Biochem Biophys Res Commun
PubMed ID: 37467664
Doi: 10.1016/j.bbrc.2023.07.018
Products & Services: Molecular Biology Reagents   
Purification and characterization of human glycerol 3-phosphate dehydrogenases (mitochondrial and cytosolic) by NAD/NADH redox method
Authors: Superior Syngkli, Bidyadhar Das
Journal: Biochimie
PubMed ID: 37481063
Doi: 10.1016/j.biochi.2023.07.015
Products & Services: Molecular Biology Reagents   
N6-Methyladenosine Promotes Translation of VEGFA to Accelerate Angiogenesis in Lung Cancer
Authors: Haisheng Zhang, Jiawang Zhou, Jiexin Li, Zhaotong Wang, Zhuojia Chen, Ziyan Lv, Lichen Ge, Guoyou Xie, Guoming Deng, Yalan Rui, Hongbing Huang, Likun Chen, Hongsheng Wang
Journal: Cancer Res
PubMed ID: 37103476
Doi: 10.1158/0008-5472.CAN-22-2449
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Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Authors: Eva-Maria Thüring, Christian Hartmann, Janesha C Maddumage, Airah Javorsky, Birgitta E Michels, Volker Gerke, Lawrence Banks, Patrick O Humbert, Marc Kvansakul, Klaus Ebnet
Journal: Commun Biol
PubMed ID: 37430142
Doi: 10.1038/s42003-023-05088-3
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