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Clostridium perfringens epsilon prototoxin mutant rpETX as a vaccine candidate against enterotoxemia
Authors: Jige Du, Tuanjie Wang, Lei Xu, Cong Wang, Ying Liu, Chenfan Pan, Xiaoyun Chen, Zhen Zhu, Yufeng Luo, Chunsheng Yin
Journal: Vaccine
PubMed ID: 37357076
Doi: 10.1016/j.vaccine.2023.06.044
Products & Services: Molecular Biology Reagents   
Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates
Authors: Steven Boeynaems, Yanniv Dorone, Yanrong Zhuang, Victoria Shabardina, Guozhong Huang, Anca Marian, Garam Kim, Anushka Sanyal, Nesli-Ece Şen, Daniel Griffith, Roberto Docampo, Keren Lasker, Iñaki Ruiz-Trillo, Georg Auburger, Alex S Holehouse, Edor Kabashi, Yi Lin, Aaron D Gitler
Journal: Mol Cell
PubMed ID: 37295429
Doi: 10.1016/j.molcel.2023.05.025
Products & Services: Molecular Biology Reagents   
MitoNEET prevents iron overload-induced insulin resistance in H9c2 cells through regulation of mitochondrial iron
Authors: Eddie Tam, Hye K Sung, Gary Sweeney
Journal: J Cell Physiol
PubMed ID: 37269467
Doi: 10.1002/jcp.31044
Products & Services: Molecular Biology Reagents   
Revealing the impact of CD70 expression on the manufacture and functions of CAR-70 T-cells based on single-cell transcriptomics
Authors: Jiali Cheng, Yuyan Zhao, Hui Hu, Ling Tang, Yuhao Zeng, Xinyue Deng, Shengnan Ding, An-Yuan Guo, Qing Li, Xiaojian Zhu
Journal: Cancer Immunol Immunother
PubMed ID: 37382633
Doi: 10.1007/s00262-023-03475-7
Comparative assessment of homemade ELISA and lateral flow assay (LFA)in the rapid, specific and sensitive detection of SARS-CoV-2 anti-nucleocapsid protein in sera of Egyptian patients
Authors: Asmaa El-Shershaby, Nahla Hussein, Esraa Ali, Amr El-Hakim, Ashraf Tabll, Mohamed Shaheen, Ibrahim Ali, Mahmoud Elshall, Yasser Shahein
Journal: J Immunoassay Immunochem
PubMed ID: 37319429
Doi: 10.1080/15321819.2023.2224865
Products & Services: Molecular Biology Reagents   
SpyTag/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion
Authors: Vili Lampinen, Stina Gröhn, Saana Soppela, Vesna Blazevic, Vesa P Hytönen, Minna M Hankaniemi
Journal: Front Cell Infect Microbiol
PubMed ID: 37424789
Doi: 10.3389/fcimb.2023.1216364
Products & Services: Peptide Synthesis   
Recombinant Bacillus Calmette-Guérin Expressing SARS-CoV-2 Chimeric Protein Protects K18-hACE2 Mice against Viral Challenge
Authors: Fábio Mambelli, Fábio V Marinho, Juvana M Andrade, Ana C V S C de Araujo, Rodrigo P F Abuna, Victor M R Fabri, Bruno P O Santos, João S da Silva, Mariana T Q de Magalhães, E Jane Homan, Luciana C C Leite, Greicy B M Dias, Nicoli Heck, Daniel A G B Mendes, Daniel S Mansur, André Báfica, Sergio C Oliveira
Journal: J Immunol
PubMed ID: 37098890
Doi: 10.4049/jimmunol.2200731
Products & Services: Peptide Synthesis   
A MYB activator, DcMYB11c, regulates carrot anthocyanins accumulation in petiole but not taproot
Authors: Ao-Qi Duan, Yuan-Jie Deng, Shan-Shan Tan, Zhi-Sheng Xu, Ai-Sheng Xiong
Journal: Plant Cell Environ
PubMed ID: 37338208
Doi: 10.1111/pce.14653
Products & Services: PCR Cloning and Subcloning   
Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
Authors: Nan Zhao, Jessica Sook Yuin Ho, Fanye Meng, Simin Zheng, Andrew P Kurland, Lu Tian, Martha Rea-Moreno, Xiangyang Song, Ji-Seon Seo, H Ümit Kaniskan, Aartjan J W Te Velthuis, Domenico Tortorella, Ya-Wen Chen, Jeffrey R Johnson, Jian Jin, Ivan Marazzi
Journal: Cell Host Microbe
PubMed ID: 37339625
Doi: 10.1016/j.chom.2023.05.030
Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity
Authors: Xiaoshen Wang, Xuzichao Li, Guimei Yu, Lingling Zhang, Chendi Zhang, Yong Wang, Fumeng Liao, Yanan Wen, Hang Yin, Xiang Liu, Yong Wei, Zhuang Li, Zengqin Deng, Heng Zhang
Journal: Cell Res
PubMed ID: 37311833
Doi: 10.1038/s41422-023-00839-7
Plasmodium GPI-anchored micronemal antigen is essential for parasite transmission through the mosquito host
Authors: Charlie Jennison, Janna M Armstrong, Dorender A Dankwa, Nina Hertoghs, Sudhir Kumar, Biley A Abatiyow, Myo Naung, Nana K Minkah, Kristian E Swearingen, Robert Moritz, Alyssa E Barry, Stefan H I Kappe, Ashley M Vaughan
Journal: Mol Microbiol
PubMed ID: 37314965
Doi: 10.1111/mmi.15078
Products & Services: Molecular Biology Reagents   
SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice
Authors: Eun Kim, Muhammad S Khan , Alessandro Ferrari , Shaohua Huang , Josè C Sammartino, Elena Percivalle, Thomas W Kenniston, Irene Cassaniti , Fausto Baldanti, Andrea Gambotto
Journal: Microbiology Spectrum
PubMed ID: 37162333
Doi: PMC10269910
Products & Services: Codon Optimization   
Li-Mg-Si bioceramics provide a dynamic immuno-modulatory and repair-supportive microenvironment for peripheral nerve regeneration
Authors: Yiting Sun , Hongjian Zhang, Yu Zhang , Zheqi Liu , Dongming He , Wanlin Xu 4, Siyi Li , Chenping Zhang , Zhen Zhang
Journal: Bioact Mater.
PubMed ID: 37292230
Doi: 10.1016/j.bioactmat.2023.05.013
Efficient expression of a cytokine combination in Saccharomyces cerevisiae for cultured meat production
Authors: Qingzi Lei, Jun Ma, Guocheng Du, Jingwen Zhou, Xin Guan
Journal: Food Research International
Doi: 10.1016/j.foodres.2023.113017
Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe
Authors: Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim
Journal: Nucleic Acids Research
PubMed ID: 37144518
Doi: 10.1093/nar/gkad363
Products & Services: ORF cDNA Clones/MolecularCloud   
Characterization of the conserved features of the NSE6 subunit of the Physcomitrium patens SMC5/6 complex
Authors: Edit Lelkes , Jitka Jemelková , Marcela Holá , Barbora Štefanovie , Peter Kolesár , Radka Vágnerová , Eva Dvořák Tomaštíková , Ales Pecinka , Karel J Angelis , Jan J Paleček
Journal: Plant J .
PubMed ID: 37191775
Doi: 10.1111/tpj.16282
Products & Services: Gene Synthesis   
13C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme–Substrate Complex of an Active, N-Linked Glycosylated Lipoxygenase
Authors: Ajay Sharma , Chris Whittington , Mohammed Jabed , S Gage Hill , Anastasiia Kostenko , Tao Yu , Pengfei Li , Peter E Doan , Brian M Hoffman , Adam R Offenbacher
Journal: Biochemistry .
PubMed ID: 37115010
Doi: 10.1021/acs.biochem.3c00119
Products & Services: Gene Synthesis   
A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex
Authors: Hong-Wei Zhang, Kun Huang, Zhan-Xi Gu, Xiao-Xian Wu, Jia-Wei Wang, Yu Zhang
Journal: Nat Commun .
PubMed ID: 37253723
Doi: 10.1038/s41467-023-38619-x
Antibacterial mechanism of the novel antimicrobial peptide Jelleine-Ic and its efficacy in controlling Pseudomonas syringae pv actinidiae in kiwifruit
Authors: Mingyu Zhang, Lifang Wang, Wei Tang, Yue Xing, Pu Liu, Xiangli Dang
Journal: Pest Manag Sci
PubMed ID: 37184207
Doi: 10.1002/ps.7548
Products & Services: Molecular Biology Reagents   
Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction
Authors: Joka Pipercevic, Bastian Kohl, Ruta Gerasimaite, Véronique Comte-Miserez, Sarah Hostachy, Thomas Müntener, Elia Agustoni, Henning Jacob Jessen, Dorothea Fiedler, Andreas Mayer, Sebastian Hiller
Journal: Nat Commun
PubMed ID: 37156835
Doi: 10.1038/s41467-023-38315-w
Products & Services: Molecular Biology Reagents   
Small-Molecule-Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death
Authors: Rita A Avelar, Amy J Armstrong, Gracie Carvette, Riya Gupta, Noah Puleo, Jose A Colina, Peronne Joseph, Alexander M Sobeck, Caitlin M O'Connor, Brynne Raines, Agharnan Gandhi, Michele L Dziubinski, Daniel S Ma, Kimberly Resnick, Sareena Singh, Kristine Zanotti, Christa Nagel, Steven Waggoner, Daffyd G Thomas, Stephanie L Skala, Junran Zhang, Goutham Narla, Analisa DiFeo
Journal: Mol Cancer Ther
PubMed ID: 36788429
Doi: 10.1158/1535-7163.MCT-21-0880
Products & Services: CRISPR Plasmids   
Validation of immunoassays for the Chlamydia trachomatis antigen Pgp3 using a chimeric monoclonal antibody
Authors: Brook Goodhew, Xiaoling Tang, Jason Goldstein, Joo Lee, Diana Martin, Sarah Gwyn
Journal: Sci Rep
PubMed ID: 37142607
Doi: 10.1038/s41598-023-33834-4
In-cell kinetic stability is an essential trait in metallo-β-lactamase evolution
Authors: Lisandro J González, Guillermo Bahr, Mariano M González, Robert A Bonomo, Alejandro J Vila
Journal: Nat Chem Biol
PubMed ID: 37188957
Doi: 10.1038/s41589-023-01319-0
Products & Services: Gene Synthesis   
Electronegative clusters modulate folding status and RNA binding of unstructured RNA-binding proteins
Authors: Steve Zaharias, Talia Fargason, Rory Greer, Yuhua Song, Jun Zhang
Journal: Protein Sci
PubMed ID: 37060324
Doi: 10.1002/pro.4643
Products & Services: Gene Synthesis   
Deficient Immune Response following SARS-CoV-2 Vaccination in Patients with Hepatobiliary Carcinoma: A Forgotten, Vulnerable Group of Patients
Authors: Malte B Monin, Leona I Baier, Jens G Gorny, Moritz Berger, Taotao Zhou, Robert Mahn, Farsaneh Sadeghlar, Christian Möhring, Christoph Boesecke, Kathrin van Bremen, Jürgen K Rockstroh, Christian P Strassburg, Anna-Maria Eis-Hübinger, Matthias Schmid, Maria A Gonzalez-Carmona
Journal: Liver Cancer
PubMed ID: 37901199
Doi: 10.1159/000529608
Products & Services: Molecular Biology Reagents   
Development of new mutant alleles and markers for and via CRISPR/Cas9-mediated mutagenesis to reduce trypsin inhibitor content and activity in soybean seeds
Authors: Zhibo Wang, Zachary Shea, Luciana Rosso, Chao Shang, Jianyong Li, Patrick Bewick, Qi Li, Bingyu Zhao, Bo Zhang
Journal: Front Plant Sci
PubMed ID: 37223818
Doi: 10.3389/fpls.2023.1111680
Structural analysis of ING3 protein and histone H3 binding
Authors: Mariola Ferreras-Gutiérrez, Belén Chaves-Arquero, Amaia González-Magaña, Nekane Merino, Ignacio Amusategui-Mateu, Sonia Huecas, Francisco J Medrano, Francisco J Blanco
Journal: Int J Biol Macromol
PubMed ID: 37148949
Doi: 10.1016/j.ijbiomac.2023.124724
A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells
Authors: Peter J Cook, Su Jung Yang, Gene I Uenishi, Annaiz Grimm, Samuel E West, Li-Jie Wang, Chester Jacobs, Andrea Repele, Travis Drow, Ahmad Boukhris, Noelle P Dahl, Karen Sommer, Andrew M Scharenberg, David J Rawlings
Journal: Mol Ther
PubMed ID: 37147803
Doi: 10.1016/j.ymthe.2023.04.021
Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation
Authors: Jayde Lockyer, Andrew Reading, Silvia Vicenzi, Caroline Delandre, Owen Marshall, Robert Gasperini, Lisa Foa, John Y Lin
Journal: biorxiv
PubMed ID: 37214843
Doi: 10.1101/2023.05.06.539674
Leptospiral imelysin (LIC_10713) is secretory, immunogenic and binds to laminin, fibronectin, and collagen IV
Authors: Abhijit Sarma, Dhandapani Gunasekaran, Homen Phukan, Akhil Baby, Suneetha Hariharan, Arun Kumar De, Debasis Bhattacharya, Sankar Natesan, Jebasingh Tennyson, Madathiparambil Gopalakrishnan Madanan
Journal: Appl Microbiol Biotechnol
PubMed ID: 37227474
Doi: 10.1007/s00253-023-12573-6
Products & Services: Molecular Biology Reagents   
CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation
Authors: Min Qiu, Zhinang Yin, Honghong Wang, Lingyu Lei, Conghui Li, Yali Cui, Rong Dai, Peiyuan Yang, Ying Xiang, Qiuzi Li, Junhui Lv, Zhuang Hu, Min Chen, Hai-Bing Zhou, Pingping Fang, Ruijing Xiao, Kaiwei Liang
Journal: Sci Adv
PubMed ID: 37205756
Doi: 10.1126/sciadv.adf8698
Products & Services: Molecular Biology Reagents   
Analysis and comparisons of gene expression changes in patient- derived neurons from ROHHAD, CCHS, and PWS
Authors: A Kaitlyn Victor, Tayler Hedgecock, Martin Donaldson, Daniel Johnson, Casey M Rand, Debra E Weese-Mayer, Lawrence T Reiter
Journal: Front Pediatr
PubMed ID: 37234859
Doi: 10.3389/fped.2023.1090084
Products & Services: Molecular Biology Reagents   
Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa
Authors: Xingyun Wang, Cong Liu, Nino Rcheulishvili, Dimitri Papukashvili, Fengfei Xie, Jiao Zhao, Xing Hu, Kaiwei Yu, Nuo Yang, Xuehua Pan, Xueyan Liu, Peng George Wang, Yunjiao He
Journal: npj Vaccines
PubMed ID: 37231060
Doi: 10.1038/s41541-023-00672-4
Products & Services: Polyclonal Antibody Services   
Sel1-like proteins and peptides are the major -derived factors stimulating oxalate transport by human intestinal epithelial cells
Authors: Donna Arvans, Changsoo Chang, Altayeb Alshaikh, Christine Tesar, Gyorgy Babnigg, Don Wolfgeher, Stephen Kron, Dionysios Antonopoulos, Mohamed Bashir, Candace Cham, Mark Musch, Eugene Chang, Andrzej Joachimiak, Hatim Hassan
Journal: Am J Physiol Cell Physiol
PubMed ID: 37125773
Doi: 10.1152/ajpcell.00466.2021
Products & Services: Peptide Synthesis   
Complete integration of carbene-transfer chemistry into biosynthesis
Authors: Jing Huang, Andrew Quest, Pablo Cruz-Morales, Kai Deng, Jose Henrique Pereira, Devon Van Cura, Ramu Kakumanu, Edward E K Baidoo, Qingyun Dan, Yan Chen, Christopher J Petzold, Trent R Northen, Paul D Adams, Douglas S Clark, Emily P Balskus, John F Hartwig, Aindrila Mukhopadhyay, Jay D Keasling
Journal: Nature
PubMed ID: 37138074
Doi: 10.1038/s41586-023-06027-2
Products & Services: Recombinant Proteins   
De Novo Computational Design of a Lipase with Hydrolysis Activity towards Middle-Chained Fatty Acid Esters
Authors: Jinsha Huang, Xiaoman Xie, Zhen Zheng, Luona Ye, Pengbo Wang, Li Xu, Ying Wu, Jinyong Yan, Min Yang, Yunjun Yan
Journal: Int J Mol Sci
PubMed ID: 37239928
Doi: 10.3390/ijms24108581
Products & Services: Gene Synthesis   
Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis
Authors: Stephanie M Bozonet, Nicholas J Magon, Abigail J Schwartfeger, Andreas Konigstorfer, Sarah G Heath, Margreet C M Vissers, Vanessa K Morris, Christoph Göbl, James M Murphy, Guy S Salvesen, Mark B Hampton
Journal: J Biol Chem
PubMed ID: 37150321
Doi: 10.1016/j.jbc.2023.104792
Products & Services: Molecular Biology Reagents   
PTPMT1 protects cardiomyocytes from necroptosis induced by γ-ray irradiation through alleviating mitochondria injury
Authors: Jing Yi, Liang Yue, Yuning Zhang, Ning Tao, Han Duan, Lin Lv, Yingxia Tan, Hua Wang
Journal: Am J Physiol Cell Physiol
PubMed ID: 37154493
Doi: 10.1152/ajpcell.00466.2022
Products & Services: Codon Optimization   
Hsa_circ_0088036 promotes nonsmall cell lung cancer progression by regulating miR-1343-3p/Bcl-3 axis through TGFβ/Smad3/EMT signaling
Authors: Peng Ge, Xin Chen, Juan Liu, Ruijun Jing, Xingxing Zhang, Hanjie Li
Journal: Mol Carcinog
PubMed ID: 37132942
Doi: 10.1002/mc.23547
KLF2 inhibits colorectal cancer progression and metastasis by inducing ferroptosis via the PI3K/AKT signaling pathway
Authors: Jia Li, Ji Ling Jiang, Yi Mei Chen, Wei Qi Lu
Journal: J Pathol Clin Res
PubMed ID: 37147883
Doi: 10.1002/cjp2.325
Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid
Authors: Hai-Fan Zhao, Liang Meng, Zhi Geng, Zeng-Qiang Gao, Yu-Hui Dong, Hai-Wei Wang, Heng Zhang
Journal: PLoS Pathog
PubMed ID: 37253057
Doi: 10.1371/journal.ppat.1011411
Products & Services: Molecular Biology Reagents   
Encapsulated Allografts Preclude Host Sensitization and Promote Ovarian Endocrine Function in Ovariectomized Young Rhesus Monkeys and Sensitized Mice
Authors: James R Day, Colleen L Flanagan, Anu David, Dennis J Hartigan-O'Connor, Mayara Garcia de Mattos Barbosa, Michele L Martinez, Charles Lee, Jenna Barnes, Evan Farkash, Mary Zelinski, Alice Tarantal, Marilia Cascalho, Ariella Shikanov
Journal: Bioengineering (Basel)
PubMed ID: 37237620
Doi: 10.3390/bioengineering10050550
Products & Services: Molecular Biology Reagents   
Phenotypic, Physiological, and Molecular Response of var under Different Light Quality Treatments Based on Leaf Color Changes
Authors: Yifan Zhang, Yang Liu, Lin Ling, Wenwen Huo, Yang Li, Lu Xu, Lili Xiang, Yujie Yang, Xingyao Xiong, Donglin Zhang, Xiaoying Yu, Yanlin Li
Journal: Plants (Basel)
PubMed ID: 37299148
Doi: 10.3390/plants12112169
Products & Services: Molecular Biology Reagents   
Purification of recombinant bacterial collagens containing structural perturbations
Authors: Sonal Gahlawat, Vikas Nanda, David I Shreiber
Journal: PLoS ONE
PubMed ID: 37196046
Doi: 10.1371/journal.pone.0285864
Products & Services: Plasmid DNA Preparation   
DPY30 Promotes Proliferation and Cell Cycle Progression of Colorectal Cancer Cells via Mediating H3K4 Trimethylation
Authors: Wei-Chao Su, Xiao-Mei Mao, Si-Yang Li, Chun-Ying Luo, Rui Fan, Hai-Feng Jiang, Lin-Jun Zhang, Ya-Tao Wang, Guo-Qiang Su, Dong-Yan Shen
Journal: Int J Med Sci
PubMed ID: 37324189
Doi: 10.7150/ijms.80073
Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV
Authors: Hiva Azizi, Jason P Knapp, Yue Li, Alice Berger, Marc-Alexandre Lafrance, Jannie Pedersen, Marc-Antoine de la Vega, Trina Racine, Chil-Yong Kang, Jamie F S Mann, Jimmy D Dikeakos, Gary Kobinger, Eric J Arts
Journal: Vaccines (Basel)
PubMed ID: 37243081
Doi: 10.3390/vaccines11050977
In silico design and validation of a novel multi-epitope vaccine candidate against structural proteins of Chikungunya virus using comprehensive immunoinformatics analyses
Authors: Shirin Mahmoodi, Javad Zamani Amirzakaria, Abdolmajid Ghasemian
Journal: PLoS ONE
PubMed ID: 37146081
Doi: 10.1371/journal.pone.0285177
Products & Services: Codon Optimization   
Profiling Enzyme Activity of l-Asparaginase II by NMR-Based Methyl Fingerprinting at Natural Abundance
Authors: Rachayita Nag, Srishti Joshi, Anurag Singh Rathore, Subhabrata Majumder
Journal: J Am Chem Soc
PubMed ID: 37154467
Doi: 10.1021/jacs.3c02154
Products & Services: DNA Sequencing   
Identification of a Novel Linear B-Cell Epitope of HbpA Protein from Using Monoclonal Antibody
Authors: Geyan Liu, Kang Wang, Zhen Yang, Xiaoyu Tang, Yung-Fu Chang, Ke Dai, Xinwei Tang, Bangdi Hu, Yiwen Zhang, Sanjie Cao, Xiaobo Huang, Qigui Yan, Rui Wu, Qin Zhao, Senyan Du, Xintian Wen, Yiping Wen
Journal: Int J Mol Sci
PubMed ID: 37239984
Doi: 10.3390/ijms24108638
Products & Services: Peptide Synthesis   
Immunogenicity and efficacy analyses of EPC002, ECA006, and EPCP009 protein subunit combinations as tuberculosis vaccine candidates
Authors: Ruihuan Wang, Xueting Fan, Yi Jiang, Guilian Li, Machao Li, Xiuqin Zhao, Xiuli Luan, Yunli Deng, Zixin Chen, Haican Liu, Kanglin Wan
Journal: Vaccine
PubMed ID: 37225573
Doi: 10.1016/j.vaccine.2023.04.003
Products & Services: Molecular Biology Reagents   

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