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An Inferred Ancestral CotA Laccase with Improved Expression and Kinetic Efficiency

Authors: Lei Lei, Lijun Zhao, Yiqia Hou, Chen Yue, Pulin Liu, Yanli Zheng, Wenfang Peng, Jiangke Yang

Journal: Int J Mol Sci

PubMed ID: 37446078

Doi: 10.3390/ijms241310901

Products & Services: Recombinant Proteins

Increasing sensitivity of antibody-antigen interactions using photo-cross-linking

Authors: Alba Torrents de la Peña, Leigh M Sewall, Rebeca de Paiva Froes Rocha, Abigail M Jackson, Payal P Pratap, Sandhya Bangaru, Christopher A Cottrell, Subhasis Mohanty, Albert C Shaw, Andrew B Ward

Journal: Cell Rep Methods

PubMed ID: 37426749

Doi: 10.1016/j.crmeth.2023.100509

Products & Services: Proteins, Expression, Isolation and Analysis

Author Correction: RNA conformational propensities determine cellular activity

Authors: Megan L Ken, Rohit Roy, Ainan Geng, Laura R Ganser, Akanksha Manghrani, Bryan R Cullen, Ursula Schulze-Gahmen, Daniel Herschlag, Hashim M Al-Hashimi

Journal: Nature

PubMed ID: 37296211

Doi: 10.1038/s41586-023-06286-z

Products & Services: Peptide Synthesis

Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation

Authors: Francisco X Galdos, Carissa Lee, Soah Lee, Sharon Paige, William Goodyer, Sidra Xu, Tahmina Samad, Gabriela V Escobar, Adrija Darsha, Aimee Beck, Rasmus O Bak, Matthew H Porteus, Sean M Wu

Journal: Elife

PubMed ID: 37284748

Doi: 10.7554/eLife.80075

Products & Services: Molecular Biology Reagents

Mycobacterium abscessus VapC5 toxin potentiates evasion of antibiotic killing by ribosome overproduction and activation of multiple resistance pathways

Authors: Eduardo A Troian, Heather M Maldonado, Unnati Chauhan, Valdir C Barth, Nancy A Woychik

Journal: Nat Commun

PubMed ID: 37349306

Doi: 10.1038/s41467-023-38844-4

Products & Services: Combinatorial DNA Libraries

The role of mechano-regulated YAP/TAZ in erectile dysfunction

Authors: Mintao Ji, Dongsheng Chen, Yinyin Shu, Shuai Dong, Zhisen Zhang, Haimeng Zheng, Xiaoni Jin, Lijun Zheng, Yang Liu, Yifei Zheng, Wensheng Zhang, Shiyou Wang, Guangming Zhou, Bingyan Li, Baohua Ji, Yong Yang, Yongde Xu, Lei Chang

Journal: Nat Commun

PubMed ID: 37353497

Doi: 10.1038/s41467-023-39009-z

Products & Services: Proteins, Expression, Isolation and Analysis

Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals

Authors: Ye Zhao, Huiling Wang, Tianhua He, Bo Ma, Guoguang Chen, Chimeng Tzeng

Journal: J Cell Commun Signal

PubMed ID: 37338798

Doi: 10.1007/s12079-023-00775-6

Products & Services: Gene Synthesis

Identification and Characterization of an HtrA Sheddase Produced by Coxiella burnetii

Authors: Ikram Omar Osman , Aurelia Caputo , Lucile Pinault , Jean-Louis Mege , Anthony Levasseur , Christian A Devaux

Journal: Int J Mol Sci .

PubMed ID: 37446087

Doi: 10.3390/ijms241310904

Products & Services: Gene Synthesis

Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors

Authors: An-Di Guo , Ke-Nian Yan, Hao Hu , Linhui Zhai , Teng-Fei Hu , Haixia Su , Yijia Chi , Jinyin Zha , Yechun Xu , Dongxin Zhao , Xiaojie Lu , Yong-Jiang Xu , Jian Zhang , Minjia Tan, Xiao-Hua Chen

Journal: Nat Chem .

PubMed ID: 37106095

Doi: 10.1038/s41557-023-01196-z

Products & Services: Peptide Synthesis

Preferential rabbit antibody responses to C-termini of NOTCH3 peptide immunogens

Authors: Soo Jung Lee , Mitchell B Gasche , Connor J Burrows , Akhil Kondepudi , Xiaojie Zhang, Michael M Wang

Journal: Sci Rep .

PubMed ID: 37280231

Doi: 10.1038/s41598-023-36067-7

Products & Services: Proteins, Expression, Isolation and Analysis

Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane

Authors: Wei Shi, Yongfei Cai, Haisun Zhu, Hanqin Peng, Jewel Voyer, Sophia Rits-Volloch, Hong Cao, Megan L Mayer, Kangkang Song, Chen Xu, Jianming Lu, Jun Zhang, Bing Chen

Journal: Nature

PubMed ID: 37285872

Doi: 10.1038/s41586-023-06273-4

Products & Services: Proteins, Expression, Isolation and Analysis

Bac to Bac System Efficiency for Preparing HPV Type 16 Virus-Like Particle Vaccine

Authors: H Razavi-Nikoo, E Behboudi, B Aghcheli, S M A Hashemi, A Moradi

Journal: Arch Razi Inst

PubMed ID: 38028838

Doi: 10.22092/ARI.2023.361975.2708

Products & Services: Proteins, Expression, Isolation and Analysis

Discovery, characterization, and redesign of potent antimicrobial thanatin orthologs from and targeting LptA

Authors: Kelly Huynh, Amanuel Kibrom, Bruce R Donald, Pei Zhou

Journal: J Struct Biol X

PubMed ID: 37416832

Doi: 10.1016/j.yjsbx.2023.100091

Products & Services: Peptide Synthesis

Development and qualification of cell-based relative potency assay for a human respiratory syncytial virus (RSV) mRNA vaccine

Authors: Hualin Helen Li, Jenny Xu, Li He, Lynne Ireland Denny, Richard R Rustandi, Geethanjali Dornadula, Brock Fiorito, Zhi-Qiang Zhang

Journal: J Pharm Biomed Anal

PubMed ID: 37336039

Doi: 10.1016/j.jpba.2023.115523

Products & Services: Proteins, Expression, Isolation and Analysis

Protein-protein interactions between tenascin-R and RPTPζ/phosphacan are critical to maintain the architecture of perineuronal nets

Authors: Ashis Sinha, Jessica Kawakami, Kimberly S Cole, Aliona Ladutska, Mary Y Nguyen, Mary S Zalmai, Brandon L Holder, Victor M Broerman, Russell T Matthews, Samuel Bouyain

Journal: J Biol Chem

PubMed ID: 37356715

Doi: 10.1016/j.jbc.2023.104952

Products & Services: Proteins, Expression, Isolation and Analysis

Compound from Magnolia officinalis Ameliorates White Matter Injury by Promoting Oligodendrocyte Maturation in Chronic Cerebral Ischemia Models

Authors: Zhi Zhang, Xin Shu, Qian Cao, Lushan Xu, Zibu Wang, Chenggang Li, Shengnan Xia, Pengfei Shao, Xinyu Bao, Liang Sun, Yuhao Xu, Yun Xu

Journal: Neurosci Bull

PubMed ID: 37291477

Doi: 10.1007/s12264-023-01068-z

Products & Services: Proteins, Expression, Isolation and Analysis

Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene

Authors: Lindsey M Vansandt, Marie-Charlotte Meinsohn, Philippe Godin, Nicholas Nagykery, Natalie Sicher, Motohiro Kano, Aki Kashiwagi, Maeva Chauvin, Hatice D Saatcioglu, Julie L Barnes, Amy G Miller, Amy K Thompson, Helen L Bateman, Elizabeth M Donelan, Raquel González, Jackie Newsom, Guangping Gao, Patricia K Donahoe, Dan Wang, William F Swanson, David Pépin

Journal: Nat Commun

PubMed ID: 37280258

Doi: 10.1038/s41467-023-38721-0

Products & Services: Codon Optimization

Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer Immunotherapy

Authors: Sara S Bashraheel, Sayed K Goda

Journal: Int J Mol Sci

PubMed ID: 37445686

Doi: 10.3390/ijms241310507

Products & Services: Peptide Synthesis

Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli

Authors: Jared Hollinger, Jiangbin Wu, Kamel M Awayda, Mitchell R O'Connell, Peng Yao

Journal: Protein Expr Purif

PubMed ID: 37329934

Doi: 10.1016/j.pep.2023.106322

Products & Services: Proteins, Expression, Isolation and Analysis

Optimization of genetic code expansion in the baculovirus expression vector system (BEVS)

Authors:

Journal: Protein Expr Purif

PubMed ID: 37269916

Doi: 10.1016/j.pep.2023.106314

Products & Services: Proteins, Expression, Isolation and Analysis

Boophilin D1, a Kunitz type protease inhibitor, as a source of inhibitors for the ZIKA virus NS2B-NS3 protease

Authors: Veronica de Moraes Manzato, Camila Di Santo, Ricardo Jose Soares Torquato, Camila Coelho, Gloria Gallo, Leon Hardy, Martin Würtele, Aparecida Sadae Tanaka

Journal: Biochimie

PubMed ID: 37364769

Doi: 10.1016/j.biochi.2023.06.010

Products & Services: Molecular Biology Reagents

Systematic Mining and Evaluation of the Sesquiterpene Skeletons as High Energy Aviation Fuel Molecules

Authors: Yanglei Huang, Ziling Ye, Xiukun Wan, Ge Yao, Jingyu Duan, Jiajia Liu, Mingdong Yao, Xiang Sun, Zixin Deng, Kun Shen, Hui Jiang, Tiangang Liu

Journal: Adv Sci (Weinh)

PubMed ID: 37271925

Doi: 10.1002/advs.202300889

Products & Services: Molecular Biology Reagents

Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3

Authors: Hayarpi Torosyan, Michael D Paul, Antoine Forget, Megan Lo, Devan Diwanji, Krzysztof Pawłowski, Nevan J Krogan, Natalia Jura, Kliment A Verba

Journal: Nat Commun

PubMed ID: 37336883

Doi: 10.1038/s41467-023-38864-0

Products & Services: Gene Synthesis

Stability and structure-activity relationship of the SPA4 peptide under ambient and stressed conditions of lung injury

Authors: Asif Alam Chowdhury, Karla Rodgers, Nachiket M Godbole, Shanjana Awasthi

Journal: RSC Adv

PubMed ID: 37350860

Doi: 10.1039/d3ra02918b

Products & Services: Molecular Biology Reagents

Assimilatory sulfate reduction in the marine methanogen Methanothermococcus thermolithotrophicus

Authors: Marion Jespersen, Tristan Wagner

Journal: Nat Microbiol

PubMed ID: 37277534

Doi: 10.1038/s41564-023-01398-8

Products & Services: DNA Sequencing

Odorant-binding protein 19 in Monochamus alternatus involved in the recognition of a volatile strongly emitted from ovipositing host pines

Authors: Ruinan Yang, Dongzhen Li, Shancheng Yi, Yi Wei, Manqun Wang

Journal: Insect Sci

PubMed ID: 37358042

Doi: 10.1111/1744-7917.13238

Products & Services: Catalog Antibody

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins

Authors: Julie Lavie, Claude Lalou, Walid Mahfouf, Jean-William Dupuy, Aurélie Lacaule, Agata Ars Cywinska, Didier Lacombe, Anne-Marie Duchêne, Anne-Aurélie Raymond, Hamid Reza Rezvani, Richard Patryk Ngondo, Giovanni Bénard

Journal: Cell Rep

PubMed ID: 37267103

Doi: 10.1016/j.celrep.2023.112579

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Modularity and diversity of target selectors in Tn7 transposons

Authors: Guilhem Faure, Makoto Saito, Sean Benler, Iris Peng, Yuri I Wolf, Jonathan Strecker, Han Altae-Tran, Edwin Neumann, David Li, Kira S Makarova, Rhiannon K Macrae, Eugene V Koonin, Feng Zhang

Journal: Mol Cell

PubMed ID: 37267947

Doi: 10.1016/j.molcel.2023.05.013

Products & Services: Molecular Biology Reagents

Performance of commercial SARS-CoV-2 wild-type and Omicron BA1 antibody assays compared with pseudovirus neutralization tests

Authors: E Habermann, L M Frommert, K Ghannam, L Nguyen My, L Gieselmann, P Tober-Lau, J Klotsche, A N Arumahandi de Silva, A Ten Hagen, J Zernicke, F Kurth, L E Sander, F Klein, G R Burmester, R Biesen, F N Albach

Journal: J Clin Virol

PubMed ID: 37354690

Doi: 10.1016/j.jcv.2023.105518

Products & Services: Proteins, Expression, Isolation and Analysis

Negatively charged, intrinsically disordered regions can accelerate target search by DNA-binding proteins

Authors: Xi Wang, Lavi S Bigman, Harry M Greenblatt, Binhan Yu, Yaakov Levy, Junji Iwahara

Journal: Nucleic Acids Res

PubMed ID: 36774964

Doi: 10.1093/nar/gkad045

Products & Services: Molecular Biology Reagents

Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation

Authors: Xiaoyun Yang , Jiaxu Wang, Simin Li , Xiaobing Li , Jingjing Gong , Zhenzhen Yan , Huan Zhou , Chen Wu , Xiuhua Liu

Journal: Nucleic Acids Res .

PubMed ID: 37334830

Doi: 10.1093/nar/gkad525

Products & Services: Codon Optimization

Schisandra extract ameliorates arthritis pathogenesis by suppressing the NF-κB and MAPK signalling pathways

Authors: Seong Jae Han, Hyemi Lee, Jiho Nam, Cheol-Ho Pan, Jimin Jeon, Siyoung Yang

Journal: J Cell Mol Med

PubMed ID: 37337779

Doi: 10.1111/jcmm.17814

Products & Services: Proteins, Expression, Isolation and Analysis

The putative role of the epipeptide EpeX in intra-species competition

Authors: Margarita Kalamara, James Abbott, Tetyana Sukhodub, Cait MacPhee, Nicola R Stanley-Wall

Journal: Microbiology (Reading)

PubMed ID: 37289492

Doi: 10.1099/mic.0.001344

Products & Services: Proteins, Expression, Isolation and Analysis

Acentrosomal spindles assemble from branching microtubule nucleation near chromosomes in Xenopus laevis egg extract

Authors: Bernardo Gouveia, Sagar U Setru, Matthew R King, Aaron Hamlin, Howard A Stone, Joshua W Shaevitz, Sabine Petry

Journal: Nat Commun

PubMed ID: 37344488

Doi: 10.1038/s41467-023-39041-z

Products & Services: Proteins, Expression, Isolation and Analysis

Broad Sarbecovirus Neutralizing Antibodies Obtained by Computational Design and Synthetic Library Screening

Authors: Xuehua Yang, Huarui Duan, Xiuying Liu, Xinhui Zhang, Shengnan Pan, Fangyuan Zhang, Peixiang Gao, Bo Liu, Jian Yang, Xiaojing Chi, Wei Yang

Journal: J Virol

PubMed ID: 37367229

Doi: 10.1128/jvi.00610-23

Products & Services: Proteins, Expression, Isolation and Analysis

Restriction of SARS-CoV-2 replication by receptor transporter protein 4 (RTP4)

Authors: Ramanjit Kaur, Takuya Tada, Nathaniel Roy Landau

Journal: MBio

PubMed ID: 37382452

Doi: 10.1128/mbio.01090-23

Products & Services: Molecular Biology Reagents

MitoNEET prevents iron overload-induced insulin resistance in H9c2 cells through regulation of mitochondrial iron

Authors: Eddie Tam, Hye K Sung, Gary Sweeney

Journal: J Cell Physiol

PubMed ID: 37269467

Doi: 10.1002/jcp.31044

Products & Services: Molecular Biology Reagents

Chimeric antigen receptor T cells targeting FcRH5 provide robust tumour-specific responses in murine xenograft models of multiple myeloma

Authors: Dongpeng Jiang, Haiwen Huang, Huimin Qin, Koukou Tang, Xiangru Shi, Tingting Zhu, Yuqing Gao, Ying Zhang, Xiaopeng Tian, Jianhong Fu, Weiwei Qu, Weilan Cai, Yang Xu, Depei Wu, Jianhong Chu

Journal: Nat Commun

PubMed ID: 37339964

Doi: 10.1038/s41467-023-39395-4

Products & Services: Recombinant Proteins

Recombinant Bacillus Calmette-Guérin Expressing SARS-CoV-2 Chimeric Protein Protects K18-hACE2 Mice against Viral Challenge

Authors: Fábio Mambelli, Fábio V Marinho, Juvana M Andrade, Ana C V S C de Araujo, Rodrigo P F Abuna, Victor M R Fabri, Bruno P O Santos, João S da Silva, Mariana T Q de Magalhães, E Jane Homan, Luciana C C Leite, Greicy B M Dias, Nicoli Heck, Daniel A G B Mendes, Daniel S Mansur, André Báfica, Sergio C Oliveira

Journal: J Immunol

PubMed ID: 37098890

Doi: 10.4049/jimmunol.2200731

Products & Services: Peptide Synthesis

KRT10 plays an important role in the release of viral genome from endosomes during H9N2 subtype AIV replication in HeLa cells

Authors: Xiangyu Huang, Guihu Yin, Bin Zhou, Yiqin Cai, Jianing Hu, Jingwen Huang, Zili Chen, Qingtao Liu, Xiuli Feng

Journal: Vet Microbiol

PubMed ID: 37406407

Doi: 10.1016/j.vetmic.2023.109824

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering BioBricks for Deoxysugar Biosynthesis and Generation of New Tetracenomycins

Authors: Heli Tirkkonen, Katelyn V. Brown, Magdalena Niemczura, Zélie Faudemer, Courtney Brown, Larissa V. Ponomareva, Yosra A. Helmy, Jon S. Thorson, S. Eric Nybo, Mikko Metsä-Ketelä, and Khaled A. Shaaban

Journal: ACS Omega

Doi: 10.1021/acsomega.3c02460

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists

Authors: Wenjing Sun , Fan Yang , Huanhuan Zhang , Qingning Yuan , Shenglong Ling , Yuanxia Wang , Pei Lv , Zelin Li , Yifan Luo , Dongsheng Liu , Wanchao Yin , Pan Shi , H Eric Xu, Changlin Tian

Journal: Cell Discov .

PubMed ID: 37391393

Doi: 10.1038/s41421-023-00564-w

Products & Services: Peptide Synthesis

Molecular Quantification and Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study

Authors: Anelis Maria Marin, Denise Kusma Wosniaki, Heloisa Bruna Soligo Sanchuki, Eduardo Cilião Munhoz, Jeanine Marie Nardin, Gabriela Silva Soares, Dhienifer Caroline Espinace, João Samuel de Holanda Farias, Bruna Veroneze, Luiz Felipe Becker, Guilherme Lima Costa, Olair Carlos Beltrame, Jaqueline Carvalho de Oliveira, Geison Cambri, Dalila Luciola Zanette, Mateus Nóbrega Aoki

Journal: Int J Mol Sci

PubMed ID: 37373266

Doi: 10.3390/ijms241210118

Products & Services: Molecular Biology Reagents

Isolation of recombinant apolipoprotein E4 N-terminal domain by foam fractionation

Authors: Kyle Lethcoe, Colin A Fox, Anouar Hafiane, Robert S Kiss, Robert O Ryan

Journal: Protein Expr Purif

PubMed ID: 37290717

Doi: 10.1016/j.pep.2023.106319

Products & Services: Molecular Biology Reagents

Inhibition of chitin deacetylases to attenuate plant fungal diseases

Authors: Lin Liu, Yeqiang Xia, Yingchen Li, Yong Zhou, Xiaofeng Su, Xiaojing Yan, Yan Wang, Wende Liu, Hongmei Cheng, Yuanchao Wang, Qing Yang

Journal: Nat Commun

PubMed ID: 37385996

Doi: 10.1038/s41467-023-39562-7

Products & Services: Gene Synthesis

Structural basis for the binding of DNP and purine nucleotides onto UCP1

Authors: Yunlu Kang, Lei Chen

Journal: Nature

PubMed ID: 37336486

Doi: 10.1038/s41586-023-06332-w

Products & Services: Gene Synthesis

Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability

Authors: Anil Kumar Vijjamarri, Xiao Niu, Matthew D Vandermeulen, Chisom Onu, Fan Zhang, Hongfang Qiu, Neha Gupta, Swati Gaikwad, Miriam L Greenberg, Paul J Cullen, Zhenguo Lin, Alan G Hinnebusch

Journal: Elife

PubMed ID: 37266577

Doi: 10.7554/eLife.85545

Products & Services: PCR Cloning and Subcloning

Complementary methods for monitoring hole-hole homodimer associated with a WuXiBody-based asymmetric bispecific antibody

Authors: Wanyuan Dong, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 37271410

Doi: 10.1016/j.pep.2023.106316

Products & Services: Proteins, Expression, Isolation and Analysis

Epigenetic Iinsights into the Senescence of Porcine Fetal Fibroblasts induced by Passaging

Authors: Jiaying Bi, Dayu Wang, Fuquan Zhu, Xinyue Lu, Yan Xie, Huijun Liu, Meixia Wang, Xu He, Yuan Jiang, Ke Liu, Mingyue Zhao, Tingzhang Wang, Juan Li

Journal: Cell Cycle

PubMed ID: 37338871

Doi: 10.1080/15384101.2023.2222521

Products & Services: Molecular Biology Reagents

A MYB activator, DcMYB11c, regulates carrot anthocyanins accumulation in petiole but not taproot

Authors: Ao-Qi Duan, Yuan-Jie Deng, Shan-Shan Tan, Zhi-Sheng Xu, Ai-Sheng Xiong

Journal: Plant Cell Environ

PubMed ID: 37338208

Doi: 10.1111/pce.14653

Products & Services: PCR Cloning and Subcloning

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