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lncRNA GHET1 has effects in development of pre-eclampsia.

J. Cell. Biochem.. 2019-03; 
LiShuhong, LiuJie, KongFanqiang, WangYuanli, LiNing, ZouYa
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Stable Cell Line Development Services … The cells were divided into three groups: normal control (NC) group, model group, and lncRNA GHET1 (lncRNA; GenScript (Nanjing) Co, Ltd, Nanjing, China) transfection group. The NC group was treated with normal treatment … Get A Quote

摘要

To explain long noncoding RNA (lncRNA) gastric carcinoma high expressed transcript 1 (GHET1) affects the mechanism in development of pre-eclampsia. The pathological changes of normal, mild, and severe pre-eclampsia were evaluated by hematoxylin and eosin staining and measured the lncRNA GHET1 expression in different tissues by reverse-transcription polymerase chain reaction. In the cell experiment, the BeWo cells were randomly divided into three groups: normal control (NC) group, model group, and lncRNA group. The JEG3 cells of the model and lncRNA groups were cultured in the hypoxia condition. The JEG3 cells invasion and migration abilities were measured by Tanswell and wound-healing assays. The rela... More

关键词

BeWo,epithelial-mesenchymal transition,gastric carcinoma high expressed transcript 1,pre-eclam