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Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer's disease treatment

Colloids and Surfaces B: Biointerfaces. 2016-05; 
Joana A.Loureiro, Bárbara Gomes, Gert Fricker, Manuel A.N.Coelho, Sandra Rocha, Maria Carmo Pereira
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Biochemicals … Amyloid-beta (Aβ(1–42) Human, purity >95%) was purchased from GenScript (Piscataway, NJ, USA). 5-FAM-(Leu)-(Pro)-(Phe)-(Phe)-(Asp), (iAβ 5 ) purity 98.9%, Mw 994.04 was purchased at GenScript (Piscataway, NJ, USA) … Get A Quote

摘要

关键词

Immuno nanoparticles, Alzheimer’s disease, Blood brain-barrier, Antibodies, Drug delivery systems, Therapeutic peptides
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