| Products/Services Used | Details | Operation |
|---|---|---|
| PCR and Cloning | … A First Strand cDNA Synthesis Kit (TakaRa, China) was used to perform reverse transcription. Primers used for real-time quantitative polymerase chain reaction (RT-qPCR) were obtained from GenScript (Nanjing, China). According … | Get A Quote |
Long non-coding RNAs (lncRNAs) are reported to play a significant role in various malignant tumors， yet their potential functions in gastric cancer are not clear. In this study， we found a novel lncRNA， named TONSL-AS1， was downregulated in gastric cancer tissues and cell lines compared with the normal. TONSL-AS1 inhibited cell migration， invasion and proliferation in SGC-7901， MGC-803?cells. Furthermore， TONSL-AS1 could suppress cell tumorigenesis in vivo. Mechanistically， TONSL-AS1's genomic neighboring gene TONSL， which was reported as a tumor suppress gene， was upregulated by TONSL. Additionally， the TONSL-AS1 was positively associated with TONSL in cancer tissues. Our study revealed t... More
