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Functional Properties of Amino Acid Side Chains as Biomarkers of Extraterrestrial Life.

Astrobiology. 2018; 
Georgiou CD.
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摘要

The present study proposes to search our solar system (Mars, Enceladus, Europa) for patterns of organic molecules that are universally associated with biological functions and structures. The functions are primarily catalytic because life could only have originated within volume/space-constrained compartments containing chemical reactions catalyzed by certain polymers. The proposed molecular structures are specific groups in the side chains of amino acids with the highest catalytic propensities related to life on Earth, that is, those that most frequently participate as key catalytic groups in the active sites of enzymes such as imidazole, thiol, guanidinium, amide, and carboxyl. Alternatively, these or other c... More

关键词

Amino acids; Catalysis; Hydrolysis; Side chains; Terminal groups