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Serology SARS-Cov-2 detection kits> | The SARS-CoV-2 N and S and SARS-CoV N genes were synthesized by GenScript and BioBasic. The SARS-CoV-2 N and SARS-CoV N genes were cloned into the pcDNA3...The recombinant SARS-CoV-2 RBD and S1 and SARS-CoV RBD proteins were produced by GenScript using the baculovirus-insect cell expression system...For performance comparison, recombinant SARS-CoV-2 RBD was also produced by GenScript in the mammalian expression system. | Get A Quote |
A robust serological test to detect neutralizing antibodies to SARS-CoV-2 is urgently needed to determine not only the infection rate, herd immunity and predicted humoral protection, but also vaccine efficacy during clinical trials and after large-scale vaccination. The current gold standard is the conventional virus neutralization test requiring live pathogen and a biosafety level 3 laboratory. Here, we report a SARS-CoV-2 surrogate virus neutralization test that detects total immunodominant neutralizing antibodies targeting the viral spike (S) protein receptor-binding domain in an isotype- and species-independent manner. Our simple and rapid test is based on antibody-mediated blockage of the interaction betwe... More