Genes Polymorphism Depicts Developmental Disruption of Common Sole Eggs

In sole aquaculture production, consistency in the quality of produced eggs throughout the year is unpredictable. genes have a crucial role in controlling embryonic development and their genetic variation could alter the phenotype dramatically. In teleosts genome duplication led paralog genes to become diverged. Direct association of polymorphism in , & of with egg viability indicates as a potential genetic marker. High Resolution Melt (HRM) analysis was carried out in 52 viable and 61 non-viable eggs collected at 54±6 hours post fertilization (hpf). Allelic and genotypic frequencies of polymorphism were analyzed and results illustrated a significantly increased risk for non-viability for minor alleles and their homozygous genotypes. Haplotype analysis demonstrated a significant recessive effect on the risk of non-viability, by increasing the odds of disrupting embryonic development up to three-fold. Phylogenetic analysis showed that the paralog genes and , are separated distinctly in two clades and presented a significant ω variation, revealing their diverged evolutionary rate.