至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

A polysaccharide from natural regulates the intestinal immunity and gut microbiota in mice with cyclophosphamide-induced intestinal injury

Food Funct. 2021-06; 
Shuping Chen, Junqiao Wang, Qiuyue Fang, Nan Dong, Qingying Fang, Steve W Cui, Shaoping Nie
Products/Services Used Details Operation
PCR and Cloning … An SYBR premix ex taq II kit was purchased from Takara Biotechnology (Dalian, China). Primers were designed by GenScript China, Ltd (Nanjing, China) … Tissues were incubated with 3% H 2 O 2 (Sangon Biotech Co. Ltd, Shanghai, China) for 10 min … Get A Quote

摘要

A polysaccharide from Cordyceps sinensis (NCSP) was reported to attenuate intestinal injury and regulate the balance of T helper (Th)1/Th2 cells in immunosuppressed mice. However, whether it influences Th17 and regulatory T (Treg) cells as well as gut ecology remains unknown. In the present study, the intestinal injury mouse model was also established by intraperitoneal injection of cyclophosphamide (Cy) for three consecutive days. NCSP was found to increase the number of CD4+ T cells, stimulate the secretion of interleukins (IL)-17 and IL-21, and the expression of transcription factor (retinoic acid-related orphan receptor (ROR)-γt). The levels of transforming growth factor (TGF)-β3 and transcription factor ... More

关键词