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Prevalence, diversity and transferability of the Tn-Tn family ICE in oral streptococci

J Oral Microbiol. 2021-03; 
Tracy Munthali Lunde, Erik Hjerde, Mohammed Al-Haroni
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DNA Sequencing … DNA sequencing primer- design tool (http://www.genscript.com/cgi … M) had evolved after acqui- sition of the gene by mobile … The block structure of these genes provides evidence for the … Get A Quote

摘要

: The Tn-Tn family of Integrative Conjugative Elements (ICE) are mobile genetic elements (MGEs) that play a role in the spread of antibiotic resistance genes. The Tn harbors the tetracycline resistance gene (M) and it has been reported in various bacterial species. The increase in the levels of tetracycline resistance among oral streptococci is of great concern primarily due to the abundance of these species in the oral cavity and their ability to act as reservoirs for antibiotic resistance genes.: In the current study, we screened 100 Norwegian clinical oral streptococcal isolates for the presence and diversity of the Tn-Tn family. In addition, we investigated the transferability the elements, and the associat... More

关键词

Integrative Conjugative Elements (ICEs), Tn6815, Tn6816, antibiotic resistance, conjugation, ddPCR, mobile genetic elements, oral streptococci, tetracycline resistance