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Efficient multinucleotide deletions using deaminase-Cas9 fusions in human cells
Authors: Siyu Chen, Zhiquan Liu, Hao Yu, Liangxue Lai, Zhanjun Li
Journal: J Genet Genomics
PubMed ID: 35421582
Doi: 10.1016/j.jgg.2022.03.007
Products & Services: Mutagenesis Services   
BRAF Modulates Lipid Use and Accumulation
Authors: Jacqueline A Turner, Emily L Paton, Robert Van Gulick, Davide Stefanoni, Francesca Cendali, Julie Reisz, Richard P Tobin, Martin McCarter, Angelo D'Alessandro, Raul M Torres, William A Robinson, Kasey L Couts, Isabel R Schlaepfer
Journal: Cancers (Basel)
PubMed ID: 35565240
Doi: 10.3390/cancers14092110
Products & Services: Mutagenesis Services   
A genetic toolkit and gene switches to limit Mycoplasma growth for biosafety applications
Authors: Alicia Broto, Erika Gaspari, Samuel Miravet-Verde, Vitor A P Martins Dos Santos, Mark Isalan
Journal: Nat Commun
PubMed ID: 35393441
Doi: 10.1038/s41467-022-29574-0
Products & Services: Mutagenesis Services   
Restoration of Sarco/Endoplasmic Reticulum Ca-ATPase Activity Functions as a Pivotal Therapeutic Target of Anti-Glutamate-Induced Excitotoxicity to Attenuate Endoplasmic Reticulum Ca Depletion
Authors: Wen Zhang, Fanghua Ye, Nan Pang, Miriam Kessi, Juan Xiong, Shimeng Chen, Jing Peng, Li Yang, Fei Yin
Journal: Front Pharmacol
PubMed ID: 35517826
Doi: 10.3389/fphar.2022.877175
Products & Services: Mutagenesis Services   
Alpha-hydroxytropolones are noncompetitive inhibitors of human RNase H1 that bind to the active site and modulate substrate binding
Authors: Nathan L Ponzar, Razia Tajwar, Nicola Pozzi, John E Tavis
Journal: J Biol Chem
PubMed ID: 35247386
Doi: 10.1016/j.jbc.2022.101790
Products & Services: Mutagenesis Services   
Glutathione binding to the plant Atm3 transporter and implications for the conformational coupling of ABC transporters
Authors: Chengcheng Fan, Douglas C Rees
Journal: Elife
PubMed ID: 35333177
Doi: 10.7554/eLife.76140
Products & Services: Mutagenesis Services   
Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation
Authors: Leena Halim, Kushal K Das, Daniel Larcombe-Young, Adam Ajina, Andrea Candelli, Reuben Benjamin, Richard Dillon, David M Davies, John Maher
Journal: Front Immunol
PubMed ID: 35222427
Doi: 10.3389/fimmu.2022.836549
Products & Services: Mutagenesis Services   
Ligand-directed bias of G protein signaling at the dopamine D2 receptor
Authors: Ee Von Moo , Kasper Harpsøe , Alexander S Hauser , Ikuo Masuho , Hans Bräuner-Osborne , David E Gloriam , Kirill A Martemyanov
Journal: Cell Chem Biol .
PubMed ID: 34302750
Doi: 10.1016/j.chembiol.2021.07.004
Products & Services: Mutagenesis Services   Gene Synthesis   
Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation
Authors: Leena Halim, Kushal K Das, Daniel Larcombe-Young, Adam Ajina, Andrea Candelli, Reuben Benjamin, Richard Dillon, David M Davies, John Maher
Journal: Front Immunol
PubMed ID: 35222427
Doi: 10.3389/fimmu.2022.836549
Products & Services: Mutagenesis Services   
Channelopathy-causing mutations in the SA/SB and HA/HB helices of K23 and K31 channels alter their apparent Ca sensitivity
Authors: Razan Orfali, Young-Woo Nam, Hai Minh Nguyen, Mohammad Asikur Rahman, Grace Yang, Meng Cui, Heike Wulff, Miao Zhang
Journal: Cell Calcium
PubMed ID: 35030515
Doi: 10.1016/j.ceca.2022.102538
Products & Services: Mutagenesis Services   

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