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The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance
Authors: James M Murithi, Ioanna Deni, Charisse Flerida A Pasaje, John Okombo, Jessica L Bridgford, Nina F Gnädig, Rachel L Edwards, Tomas Yeo, Sachel Mok, Anna Y Burkhard, Olivia Coburn-Flynn, Eva S Istvan, Tomoyo Sakata-Kato, Maria G Gomez-Lorenzo, Annie N Cowell, Kathryn J Wicht, Claire Le Manach, Gavreel F Kalantarov, Sumanta Dey, Maëlle Duffey, Benoît Laleu, Amanda K Lukens, Sabine Ottilie, Manu Vanaerschot, Ilya N Trakht, Francisco-Javier Gamo, Dyann F Wirth, Daniel E Goldberg, Audrey R Odom John, Kelly Chibale, Elizabeth A Winzeler, Jacquin C Niles, David A Fidock
Journal: Cell Chem Biol
PubMed ID: 34233174
Doi: 10.1016/j.chembiol.2021.06.006
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Structural basis of substrate recognition and translocation by human ABCA4
Authors: Tian Xie, Zike Zhang, Qi Fang, Bowen Du& Xin Gong
Journal: Nature Communications
PubMed ID: 34158497
Doi: doi.org/10.1038/s41467-021-24194-6
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Histone demethylase PHF8 promotes cell growth and metastasis of non-small-cell lung cancer through activating Wnt/β-catenin signaling pathway
Authors: Yan Hu, Hanshuo Mu, Ying Yang
Journal: Histol Histopathol
PubMed ID: 34100557
Doi: 10.14670/HH-18-349
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Pharmacokinetics, Immunogenicity and Safety Study for SHR-1309 Injection and Perjeta® in Healthy Chinese Male Volunteers
Authors: Yingzi Cui, Dongyang Cui, Xinran Ren, Xuesong Chen, Guangwen Liu, Zhengzhi Liu, Yanli Wang, Xinyao Qu, Yicheng Zhao, Haimiao Yang
Journal: Front Pharmacol
PubMed ID: 34149414
Doi: 10.3389/fphar.2021.660541
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Immune and experimental infection responses of dairy cows vaccinated with the combination of six Staphylococcus aureus proteins that are expressed during bovine intramammary infection and a triple adjuvant
Authors: Céline Ster, Marianne Allard, Julie Côté-Gravel, Simon Boulanger, Pierre Lacasse, François Malouin
Journal: Vet Immunol Immunopathol
PubMed ID: 34217108
Doi: 10.1016/j.vetimm.2021.110290
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A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge
Authors: Zachary R Sia, Xuedan He, Ali Zhang, Jann C Ang, Shuai Shao, Amal Seffouh, Wei-Chiao Huang, Michael R D'Agostino, Amir Teimouri Dereshgi, Sambhara Suryaprakash, Joaquin Ortega, Hanne Andersen, Matthew S Miller, Bruce A Davidson, Jonathan F Lovell
Journal: Proc Natl Acad Sci U S A
PubMed ID: 34050027
Doi: 10.1073/pnas.2025759118
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Directed evolution of AAV accounting for long-term and enhanced transduction of cardiovascular endothelial cells
Authors: Y B Liu, B C Xu, Y T Chen, X Yuan, J Y Liu, T Liu, G Z Du, W Jiang, Y Yang, Y Zhu, L J Chen, B S Ding, Y Q Wei, L Yang
Journal: Mol Ther Methods Clin Dev
PubMed ID: 34485601
Doi: 10.1016/j.omtm.2021.05.015
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Activation of Protein Tyrosine Phosphatase Receptor Type γ Suppresses Mechanisms of Adhesion and Survival in Chronic Lymphocytic Leukemia Cells
Authors: Alessio Montresor, Lara Toffali, Laura Fumagalli, Gabriela Constantin, Antonella Rigo, Isacco Ferrarini, Fabrizio Vinante, Carlo Laudanna
Journal: J Immunol
PubMed ID: 34162728
Doi: 10.4049/jimmunol.2001462
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CRKL is a critical target of Hh-GLI2 pathway in lung adenocarcinoma
Authors: Xiaoming Liu, Yan Hu, Bentong Yu, Kai Peng, Xin Gan
Journal: J Cell Mol Med
PubMed ID: 34076957
Doi: 10.1111/jcmm.16592
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A novel transcriptional complex on the VE-cadherin promoter regulated the downregulation of VE-cadherin in the Down Syndrome Candidate Region 1 isoform 1L-mediated angiogenesis
Authors: Shiqiang Hou, Gengming Niu, Xin Liu, Pierre M Bourbon, Dongmei Zhang, Pengfei Cui, Kevin Zhao, Dezheng Zhao, Huiyan Zeng
Journal: Microvasc Res
PubMed ID: 34146582
Doi: 10.1016/j.mvr.2021.104209
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