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Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition
Authors: Chelsie A Kadgien, Anusha Kamesh, Austen J Milnerwood
Journal: Mol Brain
PubMed ID: 34530877
Doi: 10.1186/s13041-021-00848-w
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UbiD domain dynamics underpins aromatic decarboxylation
Authors: Stephen A Marshall, Karl A P Payne, Karl Fisher, Gabriel R Titchiner, Colin Levy, Sam Hay, David Leys
Journal: Nat Commun
PubMed ID: 34417452
Doi: 10.1038/s41467-021-25278-z
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Humoral and cellular immune response and safety of two-dose SARS-CoV-2 mRNA-1273 vaccine in solid organ transplant recipients
Authors: Victoria G Hall, Victor H Ferreira, Matthew Ierullo, Terrance Ku, Tina Marinelli, Beata Majchrzak-Kita, Anila Yousuf, Vathany Kulasingam, Atul Humar, Deepali Kumar
Journal: Am J Transplant
PubMed ID: 34347934
Doi: 10.1111/ajt.16766
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NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms
Authors: Zikai Zhou, Guiqin He, Xiaoyun Zhang, Xin Lv, Xiaolin Zhang, An Liu, Shuting Xia, Hao Xie, Rui Dang, Lifang Han, Junxia Qi, Yanghong Meng, Shunying Yu, Wei Xie, Zhengping Jia
Journal: Cell Rep
PubMed ID: 34407403
Doi: 10.1016/j.celrep.2021.109515
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Extremely short bioavailability and fast pharmacodynamic effects of pMHC-based nanomedicines
Authors: Yang Yang, Kristofor K Ellestad, Santiswarup Singha, Muhammad Myn Uddin, Robert Clarke, Debajyoti Mondal, Nahir Garabatos, Patricia Solé, Cesar Fandos, Pau Serra, Pere Santamaria
Journal: J Control Release
PubMed ID: 34474072
Doi: 10.1016/j.jconrel.2021.08.043
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-Specific T Cell Functional, Memory, and Activation Profiles in QuantiFERON-Reverters Are Consistent With Controlled Infection
Authors: Cheleka A M Mpande, Pia Steigler, Tessa Lloyd, Virginie Rozot, Boitumelo Mosito, Constance Schreuder, Timothy D Reid, Nicole Bilek, Morten Ruhwald, Jason R Andrews, Mark Hatherill, Francesca Little, Thomas J Scriba, Elisa Nemes
Journal: Front Immunol
PubMed ID: 34526988
Doi: 10.3389/fimmu.2021.712480
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Miro1 functions as an inhibitory regulator of MFN at elevated mitochondrial Ca levels
Authors: Ferdinand F Fatiga, Li-Jie Wang, Tian Hsu, Jenica Irish Capuno, Chi-Yu Fu
Journal: J Cell Biochem
PubMed ID: 34431132
Doi: 10.1002/jcb.30138
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Light-Responsive Dynamic Protein Hydrogels Based on LOVTRAP
Authors: Tianyu Duan, Qingyuan Bian, Hongbin Li
Journal: Langmuir
PubMed ID: 34396769
Doi: 10.1021/acs.langmuir.1c01699
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Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge
Authors: Kerry L Hilligan, Sivaranjani Namasivayam, Chad S Clancy, Danielle O'Mard, Sandra D Oland, Shelly J Robertson, Paul J Baker, Ehydel Castro, Nicole L Garza, Bernard A P Lafont, Reed Johnson, Franca Ronchese, Katrin D Mayer-Barber, Sonja M Best, Alan Sher
Journal: biorxiv
PubMed ID: 34494021
Doi: 10.1101/2021.08.30.458273
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BB0562 is a nutritional virulence determinant with lipase activity important for Borrelia burgdorferi infection and survival in fatty acid deficient environments
Authors: Hunter W Kuhn, Amanda G Lasseter, Philip P Adams, Carlos Flores Avile, Brandee L Stone, Darrin R Akins, Travis J Jewett, Mollie W Jewett
Journal: PLoS Pathog
PubMed ID: 34415955
Doi: 10.1371/journal.ppat.1009869
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