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CVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B1351 SARS-CoV-2
Authors: Donata Hoffmann, Björn Corleis, Susanne Rauch, Nicole Roth, Janine Mühe, Nico Joel Halwe, Lorenz Ulrich, Charlie Fricke, Jacob Schön, Anna Kraft, Angele Breithaupt, Kerstin Wernike, Anna Michelitsch, Franziska Sick, Claudia Wylezich, Bernd Hoffmann, Moritz Thran, Andreas Thess, Stefan O Mueller, Thomas C Mettenleiter, Benjamin Petsch, Anca Dorhoi, Martin Beer
Journal: Nat Commun
PubMed ID: 34193869
Doi: 10.1038/s41467-021-24339-7
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SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques
Authors: Carolina Garrido, Alan D Curtis, Maria Dennis, Sachi H Pathak, Hongmei Gao, David Montefiori, Mark Tomai, Christopher B Fox, Pamela A Kozlowski, Trevor Scobey, Jennifer E Munt, Michael L Mallory, Pooja T Saha, Michael G Hudgens, Lisa C Lindesmith, Ralph S Baric, Olubukola M Abiona, Barney Graham, Kizzmekia S Corbett, Darin Edwards, Andrea Carfi, Genevieve Fouda, Koen K A Van Rompay, Kristina De Paris, Sallie R Permar
Journal: Sci Immunol
PubMed ID: 34131024
Doi: 10.1126/sciimmunol.abj3684
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Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y12 signaling pathway
Authors: Huang B, Qian Y, Xie S, Ye X, Chen H, Chen Z, Zhang L, Xu J, Hu H, Ma S, Héroux P, Wang D, Shen HM, Wu Y, Xia D
Journal: Cellular & molecular immunology
PubMed ID: 32523112
Doi: 10.1038/s41423-020-0444-5
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Open stomata 1 exhibits dual serine/threonine and tyrosine kinase activity in regulating ABA signaling
Authors: Yun Shang, Dami Yang, Yunmi Ha, Ju Yeon Lee, Jin Young Kim, Man-Ho Oh, Kyoung Hee Nam
Journal: J Exp Bot
PubMed ID: 34021330
Doi: 10.1093/jxb/erab225
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Etanercept Protected Against Cigarette Smoke Extract-Induced Inflammation and Apoptosis of Human Pulmonary Artery Endothelial Cells via Regulating TNFR1
Authors: Hong Xue, Baosong Xie, Nengluan Xu, Hongru Li, Qianshun Chen, Weiping Xie, Hong Wang
Journal: Int J Chron Obstruct Pulmon Dis
PubMed ID: 34007171
Doi: 10.2147/COPD.S295580
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XBAT31 regulates thermoresponsive hypocotyl growth through mediating degradation of the thermosensor ELF3 in Arabidopsis
Authors: Lin Lin Zhang, Yu Jian Shao, Lan Ding, Mei Jing Wang, Seth Jon Davis, Jian Xiang Liu
Journal: Sci Adv
PubMed ID: 33962946
Doi: 10.1126/sciadv.abf4427
Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses
Authors: Gwo-Yu Chuang, Chen-Hsiang Shen, Crystal Sao-Fong Cheung, Jason Gorman, Adrian Creanga, M Gordon Joyce, Kwanyee Leung, Reda Rawi, Lingshu Wang, Eun Sung Yang, Yongping Yang, Baoshan Zhang, Yi Zhang, Masaru Kanekiyo, Tongqing Zhou, Brandon J DeKosky, Barney S Graham, John R Mascola, Peter D Kwong
Journal: Front Immunol
PubMed ID: 34135892
Doi: 10.3389/fimmu.2021.662909
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Porcine circovirus type 2 infection attenuates the K63-linked ubiquitination of STING to inhibit IFN-β induction via p38-MAPK pathway
Authors: Xingchen Wu, Zhenyu Wang, Dan Qiao, Yu Yuan, Cong Han, Nan Yang, Ruizhen Li, Qian Du, Dewen Tong, Yong Huang
Journal: Vet Microbiol
PubMed ID: 33984793
Doi: 10.1016/j.vetmic.2021.109098
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A Dynamic, Ring-Forming Bactofilin Critical for Maintaining Cell Size in the Obligate Intracellular Bacterium
Authors: Mary R Brockett, Junghoon Lee, John V Cox, George W Liechti, Scot P Ouellette
Journal: Infect Immun
PubMed ID: 33941579
Doi: 10.1128/IAI.00203-21
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Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering
Authors: Nicolas O Jørgensen, Rasmus Kjøbsted, Magnus R Larsen, Jesper B Birk, Nicoline R Andersen, Bina Albuquerque, Peter Schjerling, Russell Miller, David Carling, Christian K Pehmøller, Jørgen F P Wojtaszewski
Journal: Mol Metab
PubMed ID: 34033941
Doi: 10.1016/j.molmet.2021.101259
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