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Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-κB p65 mediated modulation of microglia polarization
Authors: Mengyuan Fang, Wencui Wan, Qiuming Li, Weiwei Wan, Yang Long, Hongzhuo Liu, Xin Yang
Journal: Life Sci
PubMed ID: 33965378
Doi: 10.1016/j.lfs.2021.119567
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ALS2 regulates endosomal trafficking, postsynaptic development, and neuronal survival
Authors: Joohyung Kim, Sungdae Kim, Minyeop Nahm, Tsai-Ning Li, Hsin-Chieh Lin, Yeongjin David Kim, Jihye Lee, Chi-Kuang Yao, Seungbok Lee
Journal: J Cell Biol
PubMed ID: 33683284
Doi: 10.1083/jcb.202007112
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Afucosylated IgG Targets FcγRIV for Enhanced Tumor Therapy in Mice
Authors: Rens Braster, Marijn Bögels, Hreinn Benonisson, Manfred Wuhrer, Rosina Plomp, Arthur E H Bentlage, Rianne Korthouwer, Remco Visser, J Sjef Verbeek, Marjolein van Egmond, Gestur Vidarsson
Journal: Cancers (Basel)
PubMed ID: 34069226
Doi: 10.3390/cancers13102372
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Protective Efficacy of Rhomboid-Like Protein 3 as a Candidate Antigen Against in Chickens
Authors: Chen Chen, Di Tian, Junzhi Su, Xiaoqian Liu, Muhammad Ali A Shah, Xiangrui Li, Lixin Xu, Ruofeng Yan, Xiaokai Song
Journal: Front Microbiol
PubMed ID: 34025594
Doi: 10.3389/fmicb.2021.614229
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IgV somatic mutation of human anti-SARS-CoV-2 monoclonal antibodies governs neutralization and breadth of reactivity
Authors: Mayara Garcia de Mattos Barbosa, Hui Liu, Daniel Huynh, Greg Shelley, Evan T Keller, Brian T Emmer, Emily Sherman, David Ginsburg, Andrew A Kennedy, Andrew W Tai, Christiane Wobus, Carmen Mirabeli, Thomas M Lanigan, Milagros Samaniego, Wenzhao Meng, Aaron M Rosenfeld, Eline T Luning Prak, Jeffrey L Platt, Marilia Cascalho
Journal: JCI Insight
PubMed ID: 33769311
Doi: 10.1172/jci.insight.147386
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Evaluation of 6 Commercial SARS-CoV-2 Serology Assays Detecting Different Antibodies for Clinical Testing and Serosurveillance
Authors: Suellen Nicholson, Theo Karapanagiotidis, Arseniy Khvorov, Celia Douros, Francesca Mordant, Katherine Bond, Julian Druce, Deborah A Williamson, Damian Purcell, Sharon R Lewin, Sheena Sullivan, Kanta Subbarao, Mike Catton
Journal: Open Forum Infect Dis
PubMed ID: 34258311
Doi: 10.1093/ofid/ofab239
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SYNCRIP facilitates porcine parvovirus viral DNA replication through the alternative splicing of NS1 mRNA to promote NS2 mRNA formation
Authors: Songbiao Chen, Bichen Miao, Nannan Chen, Caiyi Chen, Ting Shao, Xuezhi Zhang, Lingling Chang, Xiujuan Zhang, Qian Du, Yong Huang, Dewen Tong
Journal: Vet Res
PubMed ID: 34034820
Doi: 10.1186/s13567-021-00938-6
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Structure of human telomerase holoenzyme with bound telomeric DNA
Authors: George E Ghanim, Adam J Fountain, Anne-Marie M van Roon, Ramya Rangan, Rhiju Das, Kathleen Collins, Thi Hoang Duong Nguyen
Journal: Nature
PubMed ID: 33883742
Doi: 10.1038/s41586-021-03415-4
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CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly
Authors: Brandon E Aubol, Jacob M Wozniak, Laurent Fattet, David J Gonzalez, Joseph A Adams
Journal: Proc Natl Acad Sci U S A
PubMed ID: 33811140
Doi: 10.1073/pnas.2018251118
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Cyclin M2 (CNNM2) knockout mice show mild hypomagnesaemia and developmental defects
Authors: Gijs A C Franken, Murat Seker, Caro Bos, Laura A H Siemons, Bram C J van der Eerden, Annabel Christ, Joost G J Hoenderop, René J M Bindels, Dominik Müller, Tilman Breiderhoff, Jeroen H F de Baaij
Journal: Sci Rep
PubMed ID: 33859252
Doi: 10.1038/s41598-021-87548-6
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