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Use of CRISPR/Cas ribonucleoproteins for high throughput gene editing of induced pluripotent stem cells

Authors: Qi Wang, Sueanne Chear, Kristof Wing, David Stellon, Minh Thuan Nguyen Tran, Jana Talbot, Alice Pébay, Alex W Hewitt, Anthony L Cook

Journal: Methods

PubMed ID: 33607266

Doi: 10.1016/j.ymeth.2021.02.009

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Regulatory T Cells Inhibit T Cell Activity by Downregulating CD137 Ligand via CD137 Trogocytosis

Authors: Khang Luu, Mugdha Vijay Patwardhan, Qun Zeng, Stina L Wickstr?m, Andreas Lundqvist, Herbert Schwarz

Journal: Cells

PubMed ID: 33572150

Doi: 10.3390/cells10020353

Products & Services: Synthetic sgRNA and crRNA Service

Development of a Broadly Applicable Cas12a-Linked Beam Unlocking Reaction for Sensitive and Specific Detection of Respiratory Pathogens Including SARS-CoV-2

Authors: Yu Wang, Donglan Liu, Huihuang Lin, Dingbin Chen, Jing Sun, Yusang Xie, Xinjie Wang, Peixiang Ma, Yan Nie, Hong Mei, Baihui Zhao, Xingxu Huang, Ge Jiang, Xianxing Jiang, Jieming Qu, Jincun Zhao, Jia Liu

Journal: ACS Chem Biol

PubMed ID: 33586431

Doi: 10.1021/acschembio.0c00840

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Small interfering RNAs (siRNAs) based gene silencing strategies for the treatment of glaucoma: Recent advancements and future perspectives

Authors: Naik S, Shreya AB, Raychaudhuri R, Pandey A, Lewis SA, Hazarika M, Bhandary SV, Rao BSS, Mutalik S

Journal: Life sciences

PubMed ID: 33159955

Doi: 10.1016/j.lfs.2020.118712

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Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19

Authors: Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Hale M, Rathe J, Stokes C, Wrenn S, Fiala B, Carter L, Hamerman JA, King NP, Gale M Jr, Campbell DJ, Rawlings DJ, Pepper M

Journal: Cell

PubMed ID: 33296701

Doi: 10.1016/j.cell.2020.11.029

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A cell atlas of the chick retina based on single-cell transcriptomics

Authors: Masahito Yamagata, Wenjun Yan, Joshua R Sanes

Journal: Elife

PubMed ID: 33393903

Doi: 10.7554/eLife.63907

Products & Services: Synthetic sgRNA and crRNA Service

Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA

Authors: Patchsung M, Jantarug K, Pattama A, Aphicho K, Suraritdechachai S, Meesawat P, Sappakhaw K, Leelahakorn N, Ruenkam T, Wongsatit T, Athipanyasilp N, Eiamthong B, Lakkanasirorat B, Phoodokmai T, Niljianskul N, Pakotiprapha D, Chanarat S, Homchan A, Tinikul R, Kamutira P, Phiwkaow K, Soithongcharoen S, Kantiwiriyawanitch C, Pongsupasa V, Trisrivirat D, Jaroensuk J, Wongnate T, Maenpuen S, Chaiyen P, Kamnerdnakta S, Swangsri J, Chuthapisith S, Sirivatanauksorn Y, Chaimayo C, Sutthent R, Kantakamalakul W, Joung J, Ladha A, Jin X, Gootenberg JS, Abudayyeh OO, Zhang F, Horthongkham N, Uttamapinant C

Journal: Nature biomedical engineering

PubMed ID: 32848209

Doi: 10.1038/s41551-020-00603-x

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Manipulating the position of DNA expression cassettes using location tags fused to dCas9 (Cas9-Lag) to improve metabolic pathway efficiency

Authors: Xie Q, Li S, Zhao D, Ye L, Li Q, Zhang X, Zhu L, Bi C

Journal: Microbial Cell Factories

PubMed ID: 33317552

Doi: 10.1186/s12934-020-01496-w

Products & Services: Synthetic sgRNA and crRNA Service

Decreasing the Susceptibility of Malignant Cells to Infection Does Not Impact the Overall Efficacy of Myxoma Virus-Based Oncolytic Virotherapy

Authors: Flores EB,Bartee E