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USP7 negatively controls global DNA methylation by attenuating ubiquitinated histone-dependent DNMT1 recruitment

Authors: Li J, Wang R, Jin J, Han M, Chen Z, Gao Y, Hu X, Zhu H, Gao H, Lu K, Shao Y, Lyu C, Lai W, Li P, Hu G, Li J, Li D, Wang H, Wu Q, Wong J

Journal: Cell Discovery

PubMed ID: 32884836

Doi: 10.1038/s41421-020-00188-4

Products & Services: Synthetic sgRNA and crRNA Service

IRE1α Promotes Zika Virus Infection via XBP1

Authors: Elena P Kolpikova, Ana R Tronco, Andreas B den Hartigh, Konner J Jackson, Takao Iwawaki, Susan L Fink

Journal: Viruses

PubMed ID: 32138181

Doi: 10.3390/v12030278

Products & Services: Synthetic sgRNA and crRNA Service

Dopamine is an aryl hydrocarbon receptor agonist

Authors: Hyejin Park, Un-Ho Jin, Keshav Karki, Arul Jayaraman, Clint H Allred, Sharon K Michelhaugh, Sandeep Mittal, Robert S Chapkin, Stephen H Safe

Journal: Biochem J

PubMed ID: 32905582

Doi: 10.1042/BCJ20200440

Products & Services: Synthetic sgRNA and crRNA Service

Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy

Authors: Tao Wan, Yuxuan Chen, Qi Pan, Xiaojie Xu, Yu Kang, Xue Gao, Feihe Huang, Chuanbin Wu, Yuan Ping

Journal: J Control Release

PubMed ID: 32169537

Doi: 10.1016/j.jconrel.2020.03.015

Products & Services: Synthetic sgRNA and crRNA Service

Targeting the MYCN-PARP-DNA Damage Response Pathway in Neuroendocrine Prostate Cancer

Authors: Zhang W, Liu B, Wu W, Li L, Broom BM, Basourakos SP, Korentzelos D, Luan Y, Wang J, Yang G, Park S, Azad AK, Cao X, Kim J, Corn PG, Logothetis CJ, Aparicio AM, Chinnaiyan AM, Navone N, Troncoso P, Thompson TC

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

PubMed ID: 29138344

Doi: 10.1158/1078-0432.CCR-17-1872

Products & Services: Synthetic sgRNA and crRNA Service

A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase

Authors: Lu J, Zhang H, Chen X, Zou Y, Li J, Wang L, Wu M, Zang J, Yu Y, Zhuang W, Xia Q, Wang J

Journal: Free radical biology & medicine

PubMed ID: 28711502

Doi: 10.1016/j.freeradbiomed.2017.07.012

Products & Services: Synthetic sgRNA and crRNA Service

Identification of two phosphorylation sites essential for annexin A1 in blood-brain barrier protection after experimental intracerebral hemorrhage in rats

Authors: Wang Z, Chen Z, Yang J, Yang Z, Yin J, Zuo G, Duan X, Shen H, Li H, Chen G