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Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives.

Authors: López Del Amo V,Leger BS,Cox KJ,Gill S,Bishop AL,Scanlon GD,Walker JA,Gantz VM,Choudhary A

Journal: Cell Reports

PubMed ID: 32610142

Doi: 10.1016/j.celrep.2020.107841

Products & Services: Synthetic sgRNA and crRNA Service

Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

Authors: Huang Zhu, Robert H Blum, Davide Bernareggi, Eivind Heggernes Ask, Zhengming Wu, Hanna Julie Hoel, Zhipeng Meng, Chengsheng Wu, Kun-Liang Guan, Karl-Johan Malmberg, Dan S Kaufman

Journal: Cell Stem Cell

PubMed ID: 32531207

Doi: 10.1016/j.stem.2020.05.008

Products & Services: Synthetic sgRNA and crRNA Service

Role of mTOR as an essential kinase in SCLC

Authors: Jeffrey A Kern, Jihye Kim, Daniel G Foster, Rangnath Mishra, Eric E Gardner, John T Poirier, Christopher Rivard, Hui Yu, James H Finigan, Afshin Dowlati, Charles M Rudin, Aik-Choon Tan

Journal: J Thorac Oncol

PubMed ID: 32599072

Doi: 10.1016/j.jtho.2020.05.026

Products & Services: Synthetic sgRNA and crRNA Service

A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection

Authors: Kaminski MM,Alcantar MA,Lape IT,Greensmith R,Huske AC,Valeri JA,Marty FM,Klämbt V,Azzi J,Akalin E,Riella LV,Collins JJ

Journal: Nature biomedical engineering

PubMed ID: 32284553

Doi: 10.1038/s41551-020-0546-5

Products & Services: Synthetic sgRNA and crRNA Service

Barcode sequence could be a good target for developing a species-specific anti-parasite agent based on CRISPR-Cas9

Authors: Yinlai Pan, Yulong Sun, Yilei Wang, Ziping Zhang