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Phosphorylation of serine residues S252, S268/S269, and S879 in p120 catenin activates migration of presomitic mesoderm in gastrulating zebrafish embryos

Authors: Ariana Kupai, Hiroko Nakahara, Kathleen M Voss, Matthew S Hirano, Alexis Rodriguez, Donna L Lackey, James F Murayama, Chase J Mathieson, Botao Shan, Emma C Horton, Grace H Curtis, Joyce Huang, Merrill B Hille

Journal: Dev Dyn

PubMed ID: 35706088

Doi: 10.1002/dvdy.508

Products & Services: Mutant Libraries

bFGF-Loaded Mesoporous Silica Nanoparticles Promote Bone Regeneration Through the Wnt/β-Catenin Signalling Pathway

Authors: Mingkui Shen, Lulu Wang, Li Feng, Yi Gao, Sijing Li, Yulan Wu, Chuangye Xu, Guoxian Pei

Journal: Int J Nanomedicine

PubMed ID: 35698561

Doi: 10.2147/IJN.S366926

Products & Services: Proteins, Expression, Isolation and Analysis

Potentiating adoptive cell therapy using synthetic IL-9 receptors

Authors: Anusha Kalbasi, Mikko Siurala, Leon L Su, Mito Tariveranmoshabad, Lora K Picton, Pranali Ravikumar, Peng Li, Jian-Xin Lin, Helena Escuin-Ordinas, Tong Da, Sarah V Kremer, Amy L Sun, Sofia Castelli, Sangya Agarwal, John Scholler, Decheng Song, Philipp C Rommel, Enrico Radaelli, Regina M Young, Warren J Leonard, Antoni Ribas, Carl H June, K Christopher Garcia

Journal: Nature

PubMed ID: 35676488

Doi: 10.1038/s41586-022-04801-2

Products & Services: Gene Synthesis

Anti-spike protein antibody responses to BNT162b2 mRNA vaccine: A single-center survey in a COVID-19 non-epidemic area in Japan

Authors: Sho Mokuda, Namiki Kawanishi, Shintaro Kuroshima, Junko Kono, Hirofumi Nakayama, Hiroshi Mieno, Masashi Kawamoto

Journal: Vaccine X

PubMed ID: 35692460

Doi: 10.1016/j.jvacx.2022.100173

Products & Services: Proteins, Expression, Isolation and Analysis

Tip60 acetylation of histone H3K4 temporally controls chromosome passenger complex localization

Authors: Ewa Niedzialkowska, Limin Liu, Cem Kuscu, Zachary Mayo, Wladek Minor, Brian D Strahl, Mazhar Adli, P Todd Stukenberg

Journal: Mol Biol Cell

PubMed ID: 35653296

Doi: 10.1091/mbc.E21-06-0283

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The DUX4 protein is a co-repressor of the progesterone and glucocorticoid nuclear receptors

Authors: Julieta Quintero, Nizar Y Saad, Sabrina M Pagnoni, Daniela K Jacquelin, Laura V Gatica, Scott Q Harper, Alberto L Rosa

Journal: FEBS Lett

PubMed ID: 35662006

Doi: 10.1002/1873-3468.14416

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HA and M2 sequences alter the replication of 2013-16 H1 live attenuated influenza vaccine infection in human nasal epithelial cell cultures

Authors: Laura M Canaday, Jessica D Resnick, Hsuan Liu, Harrison Powell, Alyssa M McCoy, Dat Nguyen, Andrew Pekosz

Journal: Vaccine

PubMed ID: 35718589

Doi: 10.1016/j.vaccine.2022.05.088

Products & Services: Plasmid DNA Preparation

Kinetics of immune responses to SARS-CoV-2 proteins in individuals with varying severity of infection and following a single dose of the AZD1222

Authors: Deshni Jayathilaka, Chandima Jeewandara, Laksiri Gomes, Tibutius Thanesh Pramanayagam Jayadas, Achala Kamaladasa, Gayasha Somathilake, Dinuka Guruge, Pradeep Darshana Pushpakumara, Thushali Ranasinghe, Inoka Sepali Aberathna, Saubhagya Danasekara, Buddini Gunathilaka, Heshan Kuruppu, Ananda Wijewickrama, Ruwan Wijayamuni, Lisa Schimanski, T K Tan, Graham S Ogg, Alain Townsend, Gathsaurie Neelika Malavige

Journal: Clin Exp Immunol

PubMed ID: 35641142

Doi: 10.1093/cei/uxac009

Products & Services: Recombinant Antibody Expression

Tailored protein-conjugated DNA nanoplatform for synergistic cancer therapy

Authors: Dingkang Liu, Ye Chen, Qun Wang, Yue Ji, Lichen Bao, Wenbing Yao, Xiangdong Gao, Jun Yin

Journal: Journal of controlled release

PubMed ID: 35452765

Doi: 10.1016/j.jconrel.2022.04.022

Products & Services: Gene Synthesis

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia

Authors: Linjiang Lao, Isabelle Bourdeau, Lucia Gagliardi, Xiao He, Wei Shi, Bingbing Hao, Minjia Tan, Yan Hu, Junzheng Peng, Benoit Coulombe, David J Torpy, Hamish S Scott, Andre Lacroix, Hongyu Luo, Jiangping Wu

Journal: Nucleic Acids Res

PubMed ID: 35687106

Doi: 10.1093/nar/gkac483

Products & Services: Proteins, Expression, Isolation and Analysis

Immunogenicity of candidate SARS-CoV-2 DNA vaccines based on the spike protein

Authors: Heeji Lim, Se Eun Kim, Yun Ha Lee, Yun-Ho Hwang, Su Hwan Kim, Mi Young Kim, Gyung Tae Chung, You-Jin Kim, Dokeun Kim, Jung-Ah Lee

Journal: Virology

PubMed ID: 35751974

Doi: 10.1016/j.virol.2022.06.006

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Construction and Characterization of T7 Bacteriophages Harboring Apidaecin-Derived Sequences

Authors: Tobias Ludwig, Ralf Hoffmann, Andor Krizsan

Journal: Curr Issues Mol Biol

PubMed ID: 35735615

Doi: 10.3390/cimb44060174

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Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents

Authors: Jaime S Rosa Duque, Xiwei Wang, Daniel Leung, Samuel M S Cheng, Carolyn A Cohen, Xiaofeng Mu, Asmaa Hachim, Yanmei Zhang, Sau Man Chan, Sara Chaothai, Kelvin K H Kwan, Karl C K Chan, John K C Li, Leo L H Luk, Leo C H Tsang, Wilfred H S Wong, Cheuk Hei Cheang, Timothy K Hung, Jennifer H Y Lam, Gilbert T Chua, Winnie W Y Tso, Patrick Ip, Masashi Mori, Niloufar Kavian, Wing Hang Leung, Sophie Valkenburg, Malik Peiris, Wenwei Tu, Yu Lung Lau

Journal: Nat Commun

PubMed ID: 35764637

Doi: 10.1038/s41467-022-31485-z

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PD-1 and ICOS coexpression identifies tumor-reactive CD4+ T cells in human solid tumors

Authors: Rebekka Duhen, Olivier Fesneau, Kimberly A Samson, Alexandra K Frye, Michael Beymer, Venkatesh Rajamanickam, David Ross, Eric Tran, Brady Bernard, Andrew D Weinberg, Thomas Duhen

Journal: J Clin Invest

PubMed ID: 35439168

Doi: 10.1172/JCI156821

Products & Services: Gene Synthesis

Rapid titration of recombinant baculoviruses based on NanoLuc secretion in early infection

Authors: Jige Li, Meng Xu, Juan Sun, Junjun Li, Jianqing Chen, Qin Chen, Jian Chen

Journal: J Virol Methods

PubMed ID: 35728698

Doi: 10.1016/j.jviromet.2022.114565

Products & Services: Insect Expression

Construction of ajmalicine and sanguinarine de novo biosynthetic pathways using stable integration sites in yeast

Authors: Tengfei Liu , Yuanwei Gou , Bei Zhang , Rui Gao , Chang Dong , Mingming Qi , Lihong Jiang , Xuanwei Ding , Chun Li , Jiazhang Lian

Journal: Biotechnol Bioeng

PubMed ID: 35060115

Doi: doi.org/10.1002/bit.28040

Products & Services: Gene Synthesis

Using large-scale multi-module NRPS to heterologously prepare highly efficient lipopeptide biosurfactants in recombinant Escherichia coli

Authors: Ting Zhang , Qiang Zhou

Journal: Enzyme Microb Technol

PubMed ID: 35660853

Doi: doi.org/10.1016/j.enzmictec.2022.110068

Products & Services: Gene Synthesis

Gold Glyconanoparticles Combined with 91-99 Peptide of the Bacterial Toxin, Listeriolysin O, Are Efficient Immunotherapies in Experimental Bladder Tumors

Authors: Hector Terán-Navarro, Andrea Zeoli, David Salines-Cuevas, Marco Marradi, Noemi Montoya, Elena Gonzalez-Lopez, Javier Gonzalo Ocejo-Vinyals, Mario Dominguez-Esteban, Jose Luis Gutierrez-Baños, Felix Campos-Juanatey, Sonsoles Yañez-Diaz, Almudena Garcia-Castaño, Fernando Rivera, Ignacio Duran, Carmen Alvarez-Dominguez

Journal: Cancers (Basel)

PubMed ID: 35626016

Doi: 10.3390/cancers14102413

Products & Services: Proteins, Expression, Isolation and Analysis

A Novel Small RNA, DsrO, in Deinococcus radiodurans Promotes Methionine Sulfoxide Reductase () Expression for Oxidative Stress Adaptation

Authors: Yun Chen, Mingming Zhao, Mengli Lv, Min Lin, Jin Wang, Kaijing Zuo

Journal: Appl Environ Microbiol

PubMed ID: 35575549

Doi: 10.1128/aem.00038-22

Products & Services: Polyclonal Antibody Services

AntiV-SGN: a universal antiviral strategy to combat both RNA and DNA viruses by destroying their nucleic acids without sequence limitation

Authors: Kun Tian, Zhen Qi, Ying Chi, Huanran Qiang, Pei Wang, Yu Liu, Guohua Zhou, Fengcai Zhu, Qinglong Guo, Shu Xu

Journal: Microb Biotechnol

PubMed ID: 35611874

Doi: 10.1111/1751-7915.14076

Products & Services: GenParts™ DNA Fragments

Selenium in Proteins: Conformational Changes Induced by Se Substitution on Methionine, as Studied in Isolated Model Peptides by Optical Spectroscopy and Quantum Chemistry

Authors: Gildas Goldsztejn, Venkateswara Rao Mundlapati, Valérie Brenner, Eric Gloaguen, Michel Mons

Journal: Molecules

PubMed ID: 35630640

Doi: 10.3390/molecules27103163

Products & Services: Catalog Peptides

Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins

Authors: Vikas Chonira, Young Do Kwon, Jason Gorman, James Brett Case, Zhiqiang Ku, Rudo Simeon, Ryan G Casner, Darcy R Harris, Adam S Olia, Tyler Stephens, Lawrence Shapiro, Hannah Boyd, Yaroslav Tsybovsky, Florian Krammer, Michael S Diamond, Peter D Kwong, Zhiqiang An, Zhilei Chen

Journal: biorxiv

PubMed ID: 35677079

Doi: 10.1101/2022.05.30.493765

Products & Services: Gene Synthesis

Developing G value as an indicator for assessing the molecular status of immobilized antibody

Authors: Dongdong Gao, Fang Cheng, Xinglong Wang, Heqing Yang, Chong Liu, Chunmei Li, Eva Murong Yang, Gang Cheng, Wei He

Journal: Colloids Surf B Biointerfaces

PubMed ID: 35665639

Doi: 10.1016/j.colsurfb.2022.112593

Products & Services: Mammalian Expression

New insights into the mechanism of iron transport through the bacterial Ftr system present in pathogens

Authors: Anne Soisig Steunou, Armelle Vigouroux, Magali Aumont-Nicaise, Stéphane Plancqueel, Alain Boussac, Soufian Ouchane, Solange Moréra

Journal: FEBS J

PubMed ID: 35527501

Doi: 10.1111/febs.16476

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α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals

Authors: Kristian Leite, Pretty Garg, F Paul Spitzner, Sofia Guerin Darvas, Mathias Bähr, Viola Priesemann, Sebastian Kügler

Journal: Front Mol Neurosci

PubMed ID: 35721317

Doi: 10.3389/fnmol.2022.868790

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Rapid, sensitive, and low-cost detection of Escherichia coli bacteria in contaminated water samples using a phage-based assay

Authors: Luis F Alonzo, Paras Jain, Troy Hinkley, Nick Clute-Reinig, Spencer Garing, Ethan Spencer, Van T T Dinh, David Bell, Sam Nugen, Kevin P Nichols, Anne-Laure M Le Ny

Journal: Sci Rep

PubMed ID: 35562180

Doi: 10.1038/s41598-022-11468-2

Products & Services: Plasmid DNA Preparation

An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

Authors: Lihong Liu, Sho Iketani, Yicheng Guo, Eswar R Reddem, Ryan G Casner, Manoj S Nair, Jian Yu, Jasper F-W Chan, Maple Wang, Gabriele Cerutti, Zhiteng Li, Nicholas C Morano, Candace D Castagna, Laura Corredor, Hin Chu, Shuofeng Yuan, Vincent Kwok-Man Poon, Chris Chun-Sing Chan, Zhiwei Chen, Yang Luo, Marcus Cunningham, Alejandro Chavez, Michael T Yin, David S Perlin, Moriya Tsuji, Kwok-Yung Yuen, Peter D Kwong, Zizhang Sheng, Yaoxing Huang, Lawrence Shapiro, David D Ho

Journal: Sci Transl Med

PubMed ID: 35438546

Doi: 10.1126/scitranslmed.abn6859

Products & Services: Plasmid DNA Preparation

Type B CTD Proteins Secreted by the Type IX Secretion System Associate with PorP-like Proteins for Cell Surface Anchorage

Authors: Dhana G Gorasia, Christine A Seers, Jacqueline E Heath, Michelle D Glew, Hamid Soleimaninejad, Catherine A Butler, Mark J McBride, Paul D Veith, Eric C Reynolds

Journal: Int J Mol Sci

PubMed ID: 35628493

Doi: 10.3390/ijms23105681

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Comparative Immunogenicity of Bacterially Expressed Soluble Trimers and Nanoparticle Displayed Influenza Hemagglutinin Stem Immunogens

Authors: Uddipan Kar, Sara Khaleeq, Priyanka Garg, Madhuraj Bhat, Poorvi Reddy, Venkada Subramanian Vignesh, Aditya Upadhyaya, Mili Das, Ghadiyaram Chakshusmathi, Suman Pandey, Somnath Dutta, Raghavan Varadarajan

Journal: Front Immunol

PubMed ID: 35720346

Doi: 10.3389/fimmu.2022.890622

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Key dimer interface residues impact the catalytic activity of 3CLpro, the main protease of SARS-CoV-2

Authors: Juliana C Ferreira, Samar Fadl, Wael M Rabeh

Journal: J Biol Chem

PubMed ID: 35568197

Doi: 10.1016/j.jbc.2022.102023

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Transiently Transfected Mammalian Cell Cultures: An Adaptable and Effective Platform for Virus-like Particle-Based Vaccines against Foot-and-Mouth Disease Virus

Authors: Michael Puckette, Victoria Primavera, Erica Martel, Jose Barrera, William Hurtle, Benjamin Clark, Barbara Kamicker, Mariceny Zurita, David Brake, John Neilan

Journal: Viruses

PubMed ID: 35632734

Doi: 10.3390/v14050989

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Comparison of Four Systems for SARS-CoV-2 Antibody at Three Time Points after SARS-CoV-2 Vaccination

Authors: Jong Do Seo, Minjeong Nam, Tae Hwan Lee, Yeon-Sun Ahn, Seon-Hyeon Shin, Hye Young Han, Hee-Won Moon

Journal: Diagnostics (Basel)

PubMed ID: 35741159

Doi: 10.3390/diagnostics12061349

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Designing a novel E2-IFN-γ fusion protein against CSFV by immunoinformatics and structural vaccinology approaches

Authors: Yanmin Zhang, Weijian Zhang, Jun Cheng, Xuping Liu, Shiwei Miao, Wen-Song Tan, Liang Zhao

Journal: Appl Microbiol Biotechnol

PubMed ID: 35524776

Doi: 10.1007/s00253-022-11919-w

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AbSE Workflow: Rapid Identification of the Coding Sequence and Linear Epitope of the Monoclonal Antibody at the Single-cell Level

Authors: Lerong Ma, HongSheng Ouyang, Ang Su, Yuanzhu Zhang, Daxin Pang, Tao Zhang, Ruize Sun, Wentao Wang, Zicong Xie, Dongmei Lv

Journal: ACS Synth Biol

PubMed ID: 35503752

Doi: 10.1021/acssynbio.2c00018

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Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD

Authors: Tim Krischuns, Catherine Isel, Petra Drncova, Maria Lukarska, Alexander Pflug, Sylvain Paisant, Vincent Navratil, Stephen Cusack, Nadia Naffakh

Journal: PLoS Pathog

PubMed ID: 35605026

Doi: 10.1371/journal.ppat.1010328

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Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants

Authors: Yaning Li, Qing Fan, Bing Zhou, Yaping Shen, Yuanyuan Zhang, Lin Cheng, Furong Qi, Shuo Song, Yingying Guo, Renhong Yan, Bin Ju, Zheng Zhang

Journal: iScience

PubMed ID: 35607524

Doi: 10.1016/j.isci.2022.104431

Products & Services: Proteins, Expression, Isolation and Analysis

Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders

Authors: Elif Eroglu, Christopher Y T Yen, Yat-Long Tsoi, Nevin Witman, Ahmed Elewa, Alberto Joven Araus, Heng Wang, Tamara Szattler, Chimezie H Umeano, Jesper Sohlmér, Alexander Goedel, András Simon, Kenneth R Chien

Journal: Nat Cell Biol

PubMed ID: 35550612

Doi: 10.1038/s41556-022-00902-2

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Structure and Mechanism of a Cold-Adapted Bacterial Lipase

Authors: Florian van der Ent, Bjarte A Lund, Linn Svalberg, Miha Purg, Ghislean Chukwu, Mikael Widersten, Geir V Isaksen, Bjørn O Brandsdal, Johan Åqvist

Journal: Biochemistry

PubMed ID: 35503728

Doi: 10.1021/acs.biochem.2c00087

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Fermentative Indole Production via Bacterial Tryptophan Synthase Alpha Subunit and Plant Indole-3-Glycerol Phosphate Lyase Enzymes

Authors: Lenny Ferrer, Melanie Mindt, Maria Suarez-Diez, Tatjana Jilg, Maja Zagorščak, Jin-Ho Lee, Kristina Gruden, Volker F Wendisch, Katarina Cankar

Journal: J Agric Food Chem

PubMed ID: 35500281

Doi: 10.1021/acs.jafc.2c01042

Products & Services: PCR Cloning and Subcloning

Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism

Authors: Shang Zhi, Zhang Congcong, Gao Zhiling, Qian Yihan, Xin Yijing, Liu Guanjie, Wang Fang, Sun Xuehua, Li Hongjie, Kong Xiaoni, Gao Yueqiu

Journal: Int J Biol Sci

PubMed ID: 35637971

Doi: 10.7150/ijbs.71431

Products & Services: Proteins, Expression, Isolation and Analysis

Comparison of pathogenicity of different subgenotype porcine reproductive and respiratory syndrome viruses isolated in China

Authors: Jie Zhang, Juan Bai, Yangyang Sun, Xing Liu, Yanni Gao, Xianwei Wang, Yuanqi Yang, Ping Jiang

Journal: Microb Pathog

PubMed ID: 35640766

Doi: 10.1016/j.micpath.2022.105607

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Complex protein interactions mediate Drosophila Lar function in muscle tissue

Authors: Jessica Kawakami, David Brooks, Rana Zalmai, Steven D Hartson, Samuel Bouyain, Erika R Geisbrecht

Journal: PLoS ONE

PubMed ID: 35622884

Doi: 10.1371/journal.pone.0269037

Products & Services: PCR Cloning and Subcloning

Sequestration of TDP-43 Aggregates by Cytoplasmic Expression of the proSAAS Chaperone

Authors: Juan R Peinado, Kriti Chaplot, Timothy S Jarvela, Edward M Barbieri, James Shorter, Iris Lindberg

Journal: ACS Chem Neurosci

PubMed ID: 35549000

Doi: 10.1021/acschemneuro.2c00156

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A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair

Authors: Susana Lechuga, Alexander X Cartagena-Rivera, Afshin Khan, Bert I Crawford, Vani Narayanan, Daniel E Conway, Jaakko Lehtimäki, Pekka Lappalainen, Florian Rieder, Michelle S Longworth, Andrei I Ivanov

Journal: FASEB J

PubMed ID: 35344227

Doi: 10.1096/fj.202200154R

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Humoral Immune Response Diversity to Different COVID-19 Vaccines: Implications for the "Green Pass" Policy

Authors: Immacolata Polvere, Alfredina Parrella, Lucrezia Zerillo, Serena Voccola, Gaetano Cardinale, Silvia D'Andrea, Jessica Raffaella Madera, Romania Stilo, Pasquale Vito, Tiziana Zotti

Journal: Front Immunol

PubMed ID: 35634315

Doi: 10.3389/fimmu.2022.833085

Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer

Authors: Tingjia Zhu, Yixuan Cen, Zhuoye Chen, Yanan Zhang, Lu Zhao, Jiaying Wang, Weiguo Lu, Xing Xie, Xinyu Wang

Journal: Cell Death Dis

PubMed ID: 35595754

Doi: 10.1038/s41419-022-04943-1

Products & Services: Proteins, Expression, Isolation and Analysis

Epitope-Based Vaccines against the Major Outer Membrane Protein Variable Domain 4 Elicit Protection in Mice

Authors: Amanda L Collar, Alexandria C Linville, Susan B Core, Kathryn M Frietze

Journal: Vaccines (Basel)

PubMed ID: 35746483

Doi: 10.3390/vaccines10060875

Products & Services: Proteins, Expression, Isolation and Analysis

Covalent Adduct Formation in Methylthio-d-ribose-1-phosphate Isomerase: Reaction Intermediate or Artifact?

Authors: Vamsee M Veeramachineni, Subashi T Ubayawardhana, Andrew S Murkin

Journal: Biochemistry

PubMed ID: 35580612

Doi: 10.1021/acs.biochem.2c00142

Products & Services: Plasmid DNA Preparation

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

Authors: Megan Lo, Amnon Sharir, Michael D Paul, Hayarpi Torosyan, Christopher Agnew, Amy Li, Cynthia Neben, Pauline Marangoni, Libin Xu, David R Raleigh, Natalia Jura, Ophir D Klein

Journal: Nat Commun

PubMed ID: 35504891

Doi: 10.1038/s41467-022-30186-x

Products & Services: Proteins, Expression, Isolation and Analysis

Coronavirus Disease 2019 Vaccine Booster Effects Are Seen in Human Milk Antibody Response

Authors: Jeffrey M Bender, Yesun Lee, Wesley A Cheng, Carolyn J Marentes Ruiz, Pia S Pannaraj

Journal: Front Nutr

PubMed ID: 35685893

Doi: 10.3389/fnut.2022.898849

Products & Services: Mammalian Expression

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