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The key sulfometuron-methyl degrading bacteria isolation based on soil bacterial phylogenetic molecular ecological networks and application for bioremediation of contaminated soil by immobilization

Authors: Hao Zhang, Chun-Yang Liu, Xin Zhang, Hui-Ying Yang, Jie Sun, Cheng-Bin Liu, Na Li

Journal: Ecotoxicol Environ Saf

PubMed ID: 35561546

Doi: 10.1016/j.ecoenv.2022.113605

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of RBMX as a splicing regulator in Parkinsonian mimetic induced alternative splicing of α-synuclein

Authors: Swaroop Thonda, Ravali L Vinnakota, Swathi V Kona, Shasi V Kalivendi

Journal: Biochim Biophys Acta Gene Regul Mech

PubMed ID: 35577270

Doi: 10.1016/j.bbagrm.2022.194825

Products & Services: GenParts™ DNA Fragments

Enhancing fluxes through the mevalonate pathway in Saccharomyces cerevisiae by engineering the HMGR and β-alanine metabolism

Authors: Surui Lu, Chenyao Zhou, Xuena Guo, Zhengda Du, Yanfei Cheng, Zhaoyue Wang, Xiuping He

Journal: Microb Biotechnol

PubMed ID: 35531990

Doi: 10.1111/1751-7915.14072

Products & Services: GenParts™ DNA Fragments

Smartly responsive DNA-miRNA hybrids packaged in exosomes for synergistic enhancement of cancer cell apoptosis

Authors: Fan Zhang, Albertina N Isak, Shiqi Yang, Yuchen Song, Lingjie Ren, Chang Feng, Guifang Chen

Journal: Nanoscale

PubMed ID: 35421879

Doi: 10.1039/d1nr08539e

Products & Services: Gene Synthesis

Glutathione S-transferase: a candidate gene for berry color in muscadine grapes (Vitis rotundifolia)

Authors: Aruna Varanasi, Margaret Worthington, Lacy Nelson, Autumn Brown, Thomas Mason Chizk, Renee Threlfall, Luke Howard, Patrick Conner, Rosa Figueroa-Balderas, Mélanie Massonnet, Dario Cantu, John R Clark

Journal: G3 (Bethesda)

PubMed ID: 35302606

Doi: 10.1093/g3journal/jkac060

Products & Services: PCR and Cloning

Crosstalk between IL-15Rα tumor-associated macrophages and breast cancer cells reduces CD8 T cell recruitment

Authors: Wenlong Zhang, Qing Zhang, Nanfei Yang, Qian Shi, Huifang Su, Tingsheng Lin, Zhonglei He, Wenxin Wang, Hongqian Guo, Pingping Shen

Journal: Cancer Commun (Lond)

PubMed ID: 35615815

Doi: 10.1002/cac2.12311

Products & Services: Peptide Synthesis

A Novel Ig Domain-Containing C-Type Lectin Triggers the Intestine-Hemocyte Axis to Regulate Antibacterial Immunity in Crab

Authors: Kaimin Zhou, Yukai Qin, Yu Song, Ke Zhao, Weijuan Pan, Xingyu Nan, Yue Wang, Qun Wang, Weiwei Li

Journal: J Immunol

PubMed ID: 35508356

Doi: 10.4049/jimmunol.2101027

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Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement

Authors: Heng Rong, Mi Qi, Jingdi Pan, Yuhan Sun, Jiawang Gao, Xiaowei Zhang, Wei Li, Bo Zhang, Xian-En Zhang, Zongqiang Cui

Journal: Front Immunol

PubMed ID: 35615356

Doi: 10.3389/fimmu.2022.905431

Products & Services: Recombinant Proteins

Structural basis of sodium-dependent bile salt uptake into the liver

Authors: Kapil Goutam, Francesco S Ielasi, Els Pardon, Jan Steyaert, Nicolas Reyes

Journal: Nature

PubMed ID: 35545671

Doi: 10.1038/s41586-022-04723-z

Products & Services: Custom Vector Construction

Duo Cadherin-Functionalized Microparticles Synergistically Induce Chondrogenesis and Cartilage Repair of Stem Cell Aggregates

Authors: Xueping Wang, Xingquan Xu, Yan Zhang, Xueying An, Xue Zhang, Guoqiang Chen, Qing Jiang, Jun Yang

Journal: Adv Healthc Mater

PubMed ID: 35485302

Doi: 10.1002/adhm.202200246

Products & Services: Mammalian Expression

Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region

Authors: Morgan S Haines, Eduardo Ramirez, Kendall B E Moore, Jessica S Fortin

Journal: Biochem Biophys Rep

PubMed ID: 35664543

Doi: 10.1016/j.bbrep.2022.101284

Products & Services: Peptide Synthesis

Antibodies targeting the European lobster (Palinurus elephas) vitellogenin developed by mRNA isolation and in-silico-designed antigenic peptides

Authors: Faustina B Cannea, Maria Cristina Follesa, Cristina Porcu, Rossano Rossino, Alessandra Olianas, Antonio Rescigno, Alessandra Padiglia

Journal: Biol Open

PubMed ID: 35452506

Doi: 10.1242/bio.059019

Products & Services: Peptide Synthesis

Small, charged proteins in salmon louse (Lepeophtheirus salmonis) secretions modulate Atlantic salmon (Salmo salar) immune responses and coagulation

Authors: Aina-Cathrine Øvergård, Helena M D Midtbø, Lars A Hamre, Michael Dondrup, Gro E K Bjerga, Øivind Larsen, Jiwan Kumar Chettri, Kurt Buchmann, Frank Nilsen, Sindre Grotmol

Journal: Sci Rep

PubMed ID: 35568726

Doi: 10.1038/s41598-022-11773-w

Products & Services: Plasmid DNA Preparation

Functional validation of a novel AAAS variant in an atypical presentation of Allgrove syndrome

Authors: Erica L Macke, Joel A Morales-Rosado, Sarah K Macklin-Mantia, Christopher T Schmitz, Björn Oskarsson, Eric W Klee, Klaas J Wierenga

Journal: Mol Genet Genomic Med

PubMed ID: 35570467

Doi: 10.1002/mgg3.1966

Products & Services: Gene Synthesis

SARS-CoV-2 BA1 variant is neutralized by vaccine booster-elicited serum but evades most convalescent serum and therapeutic antibodies

Authors: Sabrina Lusvarghi, Simon D Pollett, Sabari Nath Neerukonda, Wei Wang, Richard Wang, Russell Vassell, Nusrat J Epsi, Anthony C Fries, Brian K Agan, David A Lindholm, Christopher J Colombo, Rupal Mody, Evan C Ewers, Tahaniyat Lalani, Anuradha Ganesan, Emilie Goguet, Monique Hollis-Perry, Si'Ana A Coggins, Mark P Simons, Leah C Katzelnick, Gregory Wang, David R Tribble, Lisa Bentley, Ann E Eakin, Christopher C Broder, Karl J Erlandson, Eric D Laing, Timothy H Burgess, Edward Mitre, Carol D Weiss

Journal: Sci Transl Med

PubMed ID: 35380448

Doi: 10.1126/scitranslmed.abn8543

Products & Services: Plasmid DNA Preparation

Lactoferrin Inhibition of the Complex Formation between ACE2 Receptor and SARS CoV-2 Recognition Binding Domain

Authors: Roberta Piacentini, Laura Centi, Mattia Miotto, Edoardo Milanetti, Lorenzo Di Rienzo, Martina Pitea, Paolo Piazza, Giancarlo Ruocco, Alberto Boffi, Giacomo Parisi

Journal: Int J Mol Sci

PubMed ID: 35628247

Doi: 10.3390/ijms23105436

Products & Services: Proteins, Expression, Isolation and Analysis

Computational approach for binding prediction of SARS-CoV-2 with neutralizing antibodies

Authors: Daria Beshnova, Yan Fang, Mingjian Du, Yehui Sun, Fenghe Du, Jianfeng Ye, Zhijian James Chen, Bo Li

Journal: Comput Struct Biotechnol J

PubMed ID: 35530743

Doi: 10.1016/j.csbj.2022.04.038

Products & Services: Gene Synthesis

α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins

Authors: Weidong Jing, Jordan Lo Pilato, Callum Kay, Shouya Feng, Daniel Enosi Tuipulotu, Anukriti Mathur, Cheng Shen, Chinh Ngo, Anyang Zhao, Lisa A Miosge, Sidra A Ali, Elizabeth E Gardiner, Milena M Awad, Dena Lyras, Avril A B Robertson, Nadeem O Kaakoush, Si Ming Man

Journal: Sci Immunol

PubMed ID: 35594341

Doi: 10.1126/sciimmunol.abm1803

Products & Services: Gene Synthesis

An Immunoinformatic Strategy to Develop New Multi-epitope Vaccine

Authors:

Journal: INT J PEPT RES THER

PubMed ID: 35573911

Doi: 10.1007/s10989-022-10406-0

Products & Services: Bacterial Expression

Constitutively Active STAT5b Feminizes Mouse Liver Gene Expression

Authors: Dana Lau-Corona, Hong Ma, Cameron Vergato, Andre Sarmento-Cabral, Mercedes Del Rio-Moreno, Rhonda D Kineman, David J Waxman

Journal: Endocrinology

PubMed ID: 35396838

Doi: 10.1210/endocr/bqac046

Products & Services: Gene Synthesis

Characterization of a New Multifunctional GH20 β--Acetylglucosaminidase From sp GC72 and Its Application in Converting Chitin Into Acetyl Glucosamine

Authors: Yan Chen, Ning Zhou, Xueman Chen, Guoguang Wei, Alei Zhang, Kequan Chen, Pingkai Ouyang

Journal: Front Microbiol

PubMed ID: 35620090

Doi: 10.3389/fmicb.2022.874908

Products & Services: DNA Sequencing

Lentiviral gene therapy prevents anti-human acid α-glucosidase antibody formation in murine Pompe disease

Authors: Qiushi Liang, Eva C Vlaar, Fabio Catalano, Joon M Pijnenburg, Merel Stok, Yvette van Helsdingen, Arnold G Vulto, Wendy W J Unger, Ans T van der Ploeg, W W M Pim Pijnappel, Niek P van Til

Journal: Mol Ther Methods Clin Dev

PubMed ID: 35662813

Doi: 10.1016/j.omtm.2022.04.016

Products & Services: Mammalian Expression

Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae

Authors: Mengya Zhao, Chuanbo Zhang, Haibin Wang, Shifan He, Wenyu Lu

Journal: Biotechnol Lett

PubMed ID: 35643816

Doi: 10.1007/s10529-022-03264-9

Products & Services: Codon Optimization

A proof-of-concept study on the use of a fluorescein-based 18F-tracer for pretargeted PET

Authors: Hugo Helbert , Emily M Ploeg , Douwe F Samplonius , Simon N Blok , Ines F Antunes , Verena I Böhmer , Gert Luurtsema , Rudi A J O Dierckx , Ben L Feringa , Philip H Elsinga , Wiktor Szymanski , Wijnand Helfrich

Journal: EJNMMI Radiopharm Chem .

PubMed ID: 35239034

Doi: 10.1186/s41181-022-00155-2

Products & Services: Gene Synthesis

Thioester-Assisted Sortase-A - Mediated Ligation

Authors: Chong Zuo 1, Ruichao Ding 1, Xiangwei Wu , Yuanxia Wang , Guo-Chao Chu, Lu-Jun Liang, Huasong Ai ， Ze-Bin Tong , Junxiong Mao , Qingyun Zheng , Tian Wang , Zichen Li , Lei Liu, Demeng Sun

Journal: Angew Chem Int Ed Engl

PubMed ID: 35514243

Doi: 10.1002/anie.202201887

Products & Services: Gene Synthesis

An Arabidopsis pre-RNA processing8a (prp8a) missense allele restores splicing of a subset of mis-spliced mRNAs

Authors: Roxanna J Llinas , Jia Qi Xiong , Natalie M Clark , Sarah E Burkhart , Bonnie Bartel

Journal: Plant Physiol

PubMed ID: 35608297

Doi: 10.1093/plphys/kiac221

Products & Services: Antibody Services

Adaptation-Proof SARS-CoV-2 Vaccine Design

Authors: Yashavantha L Vishweshwaraiah, Brianna Hnath, Brendan Rackley, Jian Wang, Abhinay Gontu, Morgan Chandler, Kirill A Afonin, Suresh V Kuchipudi, Neil Christensen, Neela H Yennawar, Nikolay V Dokholyan

Journal: biorxiv

PubMed ID: 35611332

Doi: doi.org/10.1002/adfm.202206055

Products & Services: Gene Synthesis

Effective-Component Compatibility of Bufei Yishen Formula III Combined with Electroacupuncture Suppresses Inflammatory Response in Rats with Chronic Obstructive Pulmonary Disease via Regulating SIRT1/NF-B Signaling

Authors: Fanli Jin, Lanxi Zhang, Kai Chen, Yufang Miao, Yang Liu, Yange Tian, Jiansheng Li

Journal: Biomed Res Int

PubMed ID: 35586807

Doi: 10.1155/2022/3360771

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Identification and Functional Characterization of Peptides With Antimicrobial Activity From the Syphilis Spirochete,

Authors: Simon Houston, Ethan Schovanek, Kate M E Conway, Sarah Mustafa, Alloysius Gomez, Raghavendran Ramaswamy, Ayman Haimour, Martin J Boulanger, Lisa A Reynolds, Caroline E Cameron

Journal: Front Microbiol

PubMed ID: 35722306

Doi: 10.3389/fmicb.2022.888525

Products & Services: Peptide Synthesis

3,5,3'-Triiodothyronine-Loaded Liposomes Inhibit Hepatocarcinogenesis Inflammation-Associated Macrophages

Authors: Gangqi Sun, Xiaojuan Hou, Luyao Zhang, Hengyan Zhang, Changchun Shao, Fengwei Li, Chen Zong, Rong Li, Junxia Shi, Xue Yang, Li Zhang

Journal: Front Oncol

PubMed ID: 35646705

Doi: 10.3389/fonc.2022.877982

Products & Services: Proteins, Expression, Isolation and Analysis

Carboxymethylcellulose biofunctionalized ternary quantum dots for subcellular-targeted brain cancer nanotheranostics

Authors: Alexandra A P Mansur, Mayara R B Paiva, Oliver A L Cotta, Luciana M Silva, Isadora C Carvalho, Nádia S V Capanema, Sandhra M Carvalho, Érica A Costa, Nelson R Martin, Roselene Ecco, Beatriz S Santos, Silvia L Fialho, Zélia I P Lobato, Herman S Mansur

Journal: Int J Biol Macromol

PubMed ID: 35513094

Doi: 10.1016/j.ijbiomac.2022.04.207

Products & Services: Catalog Peptides

The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors

Authors: Robert D Murphy, Tiantian Chen, Jianping Lin, Rongjun He, Li Wu, Caden R Pearson, Savita Sharma, Carl D Vander Kooi, Anthony P Sinai, Zhong-Yin Zhang, Craig W Vander Kooi, Matthew S Gentry

Journal: J Biol Chem

PubMed ID: 35640720

Doi: 10.1016/j.jbc.2022.102089

Products & Services: Mutant Libraries

Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration

Authors: Zhigang Xie, Vytas A Bankaitis

Journal: Cell Rep

PubMed ID: 35649377

Doi: 10.1016/j.celrep.2022.110869

Products & Services: Polyclonal Antibody Services

Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet

Authors: Hong Lu, Xiaohong Lei, Rebecca Winkler, Savio John, Devendra Kumar, Wenkuan Li, Yazen Alnouti

Journal: Lipids Health Dis

PubMed ID: 35614477

Doi: 10.1186/s12944-022-01654-6

Products & Services: Mutagenesis Services

Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants

Authors: Lili Li, Meiling Gao, Peng Jiao, Shulong Zu, Yong-Qiang Deng, Dingyi Wan, Yang Cao, Jing Duan, Saba R Aliyari, Jie Li, Yueyue Shi, Zihe Rao, Cheng-Feng Qin, Yu Guo, Genhong Cheng, Heng Yang

Journal: Cell Biosci

PubMed ID: 35581593

Doi: 10.1186/s13578-022-00794-7

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Identification, expression and subcellular localization of Orc1 in the microsporidian Nosema bombycis

Authors: Fuzhen Sun, Guanyu Zhu, Ping He, Erjun Wei, Runpeng Wang, Qiang Wang, Xudong Tang, Yiling Zhang, Zhongyuan Shen

Journal: Gene

PubMed ID: 35609797

Doi: 10.1016/j.gene.2022.146607

Products & Services: Proteins, Expression, Isolation and Analysis

Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment

Authors: Patricia Guerrero-Ochoa, Raquel Ibáñez-Pérez, Germán Berbegal-Pinilla, Diederich Aguilar, Isabel Marzo, Francisco Corzana, Martha Minjárez-Sáenz, Javier Macías-León, Blanca Conde, Javier Raso, Ramón Hurtado-Guerrero, Alberto Anel

Journal: Biomedicines

PubMed ID: 35740244

Doi: 10.3390/biomedicines10061223

Products & Services: Plasmid DNA Preparation

A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector

Authors: Javier Martínez-García, Manuela Molina, Leticia Odriozola, Angie Molina, Gloria González-Aseguinolaza, Nicholas D Weber, Cristian Smerdou

Journal: Cell Biosci

PubMed ID: 35641984

Doi: 10.1186/s13578-022-00803-9

Products & Services: PCR Cloning and Subcloning

Electrostatics Drive the Molecular Chaperone BiP to Preferentially Bind Oligomerized States of a Client Protein

Authors: Erin E Deans, Judy L M Kotler, Wei-Shao Wei, Timothy O Street

Journal: J Mol Biol

PubMed ID: 35597552

Doi: 10.1016/j.jmb.2022.167638

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Atypical B cells up-regulate costimulatory molecules during malaria and secrete antibodies with T follicular helper cell support

Authors: Christine S Hopp, Jeff Skinner, Sarah L Anzick, Christopher M Tipton, Mary E Peterson, Shanping Li, Safiatou Doumbo, Kassoum Kayentao, Aissata Ongoiba, Craig Martens, Boubacar Traore, Peter D Crompton

Journal: Sci Immunol

PubMed ID: 35559666

Doi: 10.1126/sciimmunol.abn1250

Products & Services: Recombinant Proteins

Candidate Chemosensory Genes Identified in the Adult Antennae of and Binding Property of Odorant-Binding Protein 15

Authors: Xiao Li, Jian-Wen Li, Wen-Xiu Sun, Wei Li, Hua-Yuan Gao, Tong-Xian Liu, Ming-Jing Qu

Journal: Front Physiol

PubMed ID: 35711318

Doi: 10.3389/fphys.2022.907667

Products & Services: Proteins, Expression, Isolation and Analysis

Structural variation between neuropeptide isoforms affects function in the lobster cardiac system

Authors: Audrey J Muscato, Daniel J Powell, Warsameh Bulhan, Evalyn S Mackenzie, Alixander Pupo, Madeline Rolph, Andrew E Christie, Patsy S Dickinson

Journal: Gen Comp Endocrinol

PubMed ID: 35623446

Doi: 10.1016/j.ygcen.2022.114065

Products & Services: Peptide Synthesis

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation

Authors: Robert Blassberg, Harshil Patel, Thomas Watson, Mina Gouti, Vicki Metzis, M Joaquina Delás, James Briscoe

Journal: Nat Cell Biol

PubMed ID: 35550614

Doi: 10.1038/s41556-022-00910-2

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Optimization of the antimicrobial peptide Bac7 by deep mutational scanning

Authors: Philipp Koch, Steven Schmitt, Alexander Heynisch, Anja Gumpinger, Irene Wüthrich, Marina Gysin, Dimitri Shcherbakov, Sven N Hobbie, Sven Panke, Martin Held

Journal: BMC Biol

PubMed ID: 35578204

Doi: 10.1186/s12915-022-01304-4

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Immunogenicity, safety, and antiphospholipid antibodies after SARS-CoV-2 vaccine in patients with primary antiphospholipid syndrome

Authors: Flavio Signorelli, Gustavo Guimarães Moreira Balbi, Nadia E Aikawa, Clovis A Silva, Léonard de Vinci Kanda Kupa, Ana C Medeiros-Ribeiro, Emily Fn Yuki, Sandra G Pasoto, Carla Gs Saad, Eduardo F Borba, Luciana Parente Costa Seguro, Tatiana Pedrosa, Vitor Antonio de Angeli Oliveira, Ana Luisa Cerqueira de Sant'Ana Costa, Carolina T Ribeiro, Roseli Eliana Beseggio Santos, Danieli Castro Oliveira Andrade, Eloisa Bonfá

Journal: Lupus

PubMed ID: 35593174

Doi: 10.1177/09612033221102073

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CBR3-AS1 Accelerates the Malignant Proliferation of Gestational Choriocarcinoma Cells by Stabilizing SETD4

Authors: Yajuan Zhang, Hongxiu Zhang, Xiaolei Zhang, Bin Liu

Journal: Dis Markers

PubMed ID: 35655916

Doi: 10.1155/2022/7155525

Products & Services: Plasmid DNA Preparation

IgG targeting distinct seasonal coronavirus- conserved SARS-CoV-2 spike subdomains correlates with differential COVID-19 disease outcomes

Authors: Jose L Garrido, Matías A Medina, Felipe Bravo, Sarah McGee, Francisco Fuentes-Villalobos, Mario Calvo, Yazmin Pinos, James W Bowman, Christopher D Bahl, Maria Ines Barria, Rebecca A Brachman, Raymond A Alvarez

Journal: Cell Rep

PubMed ID: 35617962

Doi: 10.1016/j.celrep.2022.110904

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BCG-Based Vaccines Elicit Antigen-Specific Adaptive and Trained Immunity against SARS-CoV-2 and

Authors: Jorge A Soto, Fabián E Díaz, Angello Retamal-Díaz, Nicolás M S Gálvez, Felipe Melo-González, Alejandro Piña-Iturbe, Mario A Ramírez, Karen Bohmwald, Pablo A González, Susan M Bueno, Alexis M Kalergis

Journal: Vaccines (Basel)

PubMed ID: 35632475

Doi: 10.3390/vaccines10050721

Products & Services: Proteins, Expression, Isolation and Analysis

Thymosin α-1 Reverses M2 Polarization of Tumor-Associated Macrophages during Efferocytosis

Authors: Yi-Ting Wei, Xu-Ru Wang, Chunguang Yan, Fang Huang, Yunpeng Zhang, Xueming Liu, Zhi-Fa Wen, Xiao-Tong Sun, Yue Zhang, Yong-Qiang Chen, Rong Gao, Ning Pan, Li-Xin Wang

Journal: Cancer Res

PubMed ID: 35364609

Doi: 10.1158/0008-5472.CAN-21-4260

Products & Services: Custom Vector Construction

Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant

Authors: Kanwal Khan, Salman Ali Khan, Khurshid Jalal, Zaheer Ul-Haq, Reaz Uddin

Journal: Virology

PubMed ID: 35576833

Doi: 10.1016/j.virol.2022.05.001

Products & Services: Peptoid Synthesis

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