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Rapid sequence evolution is associated with genetic incompatibilities in the plastid Clp complex

Authors: Salah E Abdel-Ghany, Lisa M LaManna, Haleakala T Harroun, Pal Maliga, Daniel B Sloan

Journal: Plant Mol Biol

PubMed ID: 35039977

Doi: 10.1007/s11103-022-01241-4

Products & Services: PCR Cloning and Subcloning

Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Authors: Diego Angosto-Bazarra, Cristina Alarcón-Vila, Laura Hurtado-Navarro, María C Baños, Jack Rivers-Auty, Pablo Pelegrín

Journal: BMC Biol

PubMed ID: 34996441

Doi: 10.1186/s12915-021-01220-z

Products & Services: Mammalian Expression

A Palette of Fluorescent A42 Peptides Labelled at a Range of Surface-Exposed Sites

Authors: Dev Thacker, Mara Bless, Mohammad Barghouth, Enming Zhang, Sara Linse

Journal: Int J Mol Sci

PubMed ID: 35163577

Doi: 10.3390/ijms23031655

Products & Services: Bacterial Expression

USF1 Transcriptionally Regulates UGT1A3 and Promotes Lung Adenocarcinoma Progression by Regulating Neurotrophin Signaling Pathway

Authors: Yu Wang, Yun-Xia Zhao, Xiang-Wei Zhang, Yuan-Zhu Jiang, Wei Ma, Lin Zhang, Wei Dong

Journal: Front Mol Biosci

PubMed ID: 35155573

Doi: 10.3389/fmolb.2022.758968

Products & Services: Peptide Synthesis

Ion currents through Kir potassium channels are gated by anionic lipids

Authors: Ruitao Jin, Sitong He, Katrina A Black, Oliver B Clarke, Di Wu, Jani R Bolla, Paul Johnson, Agalya Periasamy, Ahmad Wardak, Peter Czabotar, Peter M Colman, Carol V Robinson, Derek Laver, Brian J Smith, Jacqueline M Gulbis

Journal: Nat Commun

PubMed ID: 35079013

Doi: 10.1038/s41467-022-28148-4

Products & Services: Mutant Libraries

Covalent coupling of Spike's receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2

Authors:

Journal: Sci Rep

PubMed ID: 35027583

Doi: 10.1038/s41598-021-03675-0

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Cardiac troponin T and autoimmunity in skeletal muscle aging

Authors: Tan Zhang, Xin Feng, Juan Dong, Zherong Xu, Bo Feng, Karen M Haas, Peggy M Cawthon, Kristen M Beavers, Barbara Nicklas, Stephen Kritchevsky

Journal: Geroscience

PubMed ID: 35034279

Doi: 10.1007/s11357-022-00513-7

Products & Services: Proteins, Expression, Isolation and Analysis

Fifty Shades of E: Innate Immune Evasion by the Viral Endonucleases of All Pestivirus Species

Authors: Elena de Martin, Matthias Schweizer

Journal: Viruses

PubMed ID: 35215858

Doi: 10.3390/v14020265

Products & Services: Proteins, Expression, Isolation and Analysis

DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3

Authors: Feng Hu, Ki On Fong, May Pui Lai Cheung, Jessica Aijia Liu, Rui Liang, Tsz Wai Li, Rakesh Sharma, Philip Pun-Ching Ip, Xintao Yang, Martin Cheung

Journal: Adv Sci (Weinh)

PubMed ID: 35088579

Doi: 10.1002/advs.202105226

Products & Services: Catalog Antibody

Elucidating the 3D Structure of a Surface Membrane Antigen from as a Serodiagnostic Biomarker of Chagas Disease

Authors: Flavio Di Pisa, Stefano De Benedetti, Enrico Mario Alessandro Fassi, Mauro Bombaci, Renata Grifantini, Angelo Musicò, Roberto Frigerio, Angela Pontillo, Cinzia Rigo, Sandra Abelli, Romualdo Grande, Nadia Zanchetta, Davide Mileto, Alessandro Mancon, Alberto Rizzo, Alessandro Gori, Marina Cretich, Giorgio Colombo, Martino Bolognesi, Louise Jane Gourlay

Journal: Vaccines (Basel)

PubMed ID: 35062732

Doi: 10.3390/vaccines10010071

Products & Services: Proteins, Expression, Isolation and Analysis

Mechanism of MyD88S mediated signal termination

Authors: Katarzyna Pustelny, Katarzyna Kuska, Andrzej Gorecki, Bogdan Musielak, Ewelina Dobosz, Benedykt Wladyka, Joanna Koziel, Anna Czarna, Tad Holak, Grzegorz Dubin

Journal: Cell Commun Signal

PubMed ID: 35057808

Doi: 10.1186/s12964-021-00811-1

Products & Services: PCR Cloning and Subcloning

Antigenic and immunogenic properties of recombinant proteins consisting of two immunodominant African swine fever virus proteins fused with bacterial lipoprotein OprI

Authors: Guanglei Zhang, Wei Liu, Zhan Gao, Yanyan Chang, Sicheng Yang, Qian Peng, Sudan Ge, Bijing Kang, Junjun Shao, Huiyun Chang

Journal: Virol J

PubMed ID: 35062983

Doi: 10.1186/s12985-022-01747-9

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RIPPA: Identification of MHC-II Binding Peptides from Antigen Using a Yeast Display-Based Approach

Authors: Rongzeng Liu, Wei Jiang, Ying Li, Elizabeth D Mellins

Journal: Curr Protoc

PubMed ID: 35041265

Doi: 10.1002/cpz1.350

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Three Specific Potential Epitopes That Could Be Recognized by T Cells of Convalescent COVID-19 Patients Were Identified From Spike Protein

Authors: Yunwen Zhang, Zhengrong Yang, Mingyuan Tang, Hao Li, Tian Tang, Guilian Li, Yifan Zhong, Xiaomin Zhang, Xiaohui Wang, Chuan Wang

Journal: Front Immunol

PubMed ID: 35154095

Doi: 10.3389/fimmu.2022.752622

Products & Services: Peptide Synthesis

Severe Natural Outbreak of in Gilthead Seabream Produces Leukocyte Mobilization and Innate Immunity at the Gill Tissue

Authors: Laura Cervera, Carmen González-Fernández, Marta Arizcun, Alberto Cuesta, Elena Chaves-Pozo

Journal: Int J Mol Sci

PubMed ID: 35055122

Doi: 10.3390/ijms23020937

Products & Services: Peptide Synthesis

Isoforms of the neuropeptide myosuppressin differentially modulate the cardiac neuromuscular system of the American lobster,

Authors: Emily R Oleisky, Meredith E Stanhope, J Joe Hull, Patsy S Dickinson

Journal: J Neurophysiol

PubMed ID: 35044860

Doi: 10.1152/jn.00338.2021

Products & Services: Peptide Synthesis

The ectomycorrhizal basidiomycete Laccaria bicolor releases a GH28 polygalacturonase that plays a key role in symbiosis establishment

Authors: Feng Zhang, Aurore Labourel, Mireille Haon, Minna Kemppainen, Emilie Da Silva Machado, Nicolas Brouilly, Claire Veneault-Fourrey, Annegret Kohler, Marie-Noëlle Rosso, Alejandro Pardo, Bernard Henrissat, Jean-Guy Berrin, Francis Martin

Journal: New Phytol

PubMed ID: 34942023

Doi: 10.1111/nph.17940

Products & Services: Recombinant Antibody Expression

Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden

Authors: Julia Femel, Luuk van Hooren, Melanie Herre, Jessica Cedervall, Falk Saupe, Elisabeth J M Huijbers, Danielle R J Verboogen, Matthias Reichel, Victor L Thijssen, Arjan W Griffioen, Lars Hellman, Anna Dimberg, Anna-Karin Olsson

Journal: Cancer Immunol Immunother

PubMed ID: 35018481

Doi: 10.1007/s00262-021-03139-4

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Experimental Periodontitis Deteriorated Atherosclerosis Associated With Trimethylamine N-Oxide Metabolism in Mice

Authors: Lingling Xiao, Lingyan Huang, Xin Zhou, Dan Zhao, Yan Wang, Haiyan Min, Shiyu Song, Weibin Sun, Qian Gao, Qingang Hu, Sijing Xie

Journal: Front Cell Infect Microbiol

PubMed ID: 35118014

Doi: 10.3389/fcimb.2021.820535

Products & Services: Custom DNA/RNA Oligos

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities

Authors: Raffaele Iennaco, Giulio Formenti, Camilla Trovesi, Riccardo Lorenzo Rossi, Chiara Zuccato, Tiziana Lischetti, Vittoria Dickinson Bocchi, Andrea Scolz, Cristina Martínez-Labarga, Olga Rickards, Michela Pacifico, Angelica Crottini, Anders Pape Møller, Richard Zhenghuan Chen, Thomas Francis Vogt, Giulio Pavesi, David Stephen Horner, Nicola Saino, Elena Cattaneo

Journal: Cell Death Differ

PubMed ID: 34974533

Doi: 10.1038/s41418-021-00914-9

Products & Services: PCR Cloning and Subcloning

Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids

Authors: Icaro Putinhon Caruso, Vitor Dos Santos Almeida, Mariana Juliani do Amaral, Guilherme Caldas de Andrade, Gabriela Rocha de Araújo, Talita Stelling de Araújo, Jéssica Moreira de Azevedo, Glauce Moreno Barbosa, Leonardo Bartkevihi, Peter Reis Bezerra, Katia Maria Dos Santos Cabral, Isabella Otênio de Lourenço, Clara L F Malizia-Motta, Aline de Luna Marques, Nathane Cunha Mebus-Antunes, Thais Cristtina Neves-Martins, Jéssica Maróstica de Sá, Karoline Sanches, Marcos Caique Santana-Silva, Ariana Azevedo Vasconcelos, Marcius da Silva Almeida, Gisele Cardoso de Amorim, Cristiane Dinis Anobom, Andrea T Da Poian, Francisco Gomes-Neto, Anderson S Pinheiro, Fabio C L Almeida

Journal: Int J Biol Macromol

PubMed ID: 35077748

Doi: 10.1016/j.ijbiomac.2022.01.121

Products & Services: PCR Cloning and Subcloning

Improving one-step scarless genome editing in by combining co-CRISPR selection with sgRNA target site masking

Authors: Katharina J Götze, Achmed Mrestani, Paula Beckmann, Knut Krohn, Diana Le Duc, Akhil Velluva, Mathias A Böhme, Manfred Heckmann, Rami Abou Jamra, Johannes R Lemke, Hendrik Bläker, Nicole Scholz, Dmitrij Ljaschenko, Tobias Langenhan

Journal: Biol Methods Protoc

PubMed ID: 35087953

Doi: 10.1093/biomethods/bpac003

Products & Services: Plasmid DNA Preparation

A murine Skint6 W168X allele contributes to autoimmune disease in a transgenic model

Authors: Jiyu Ju, Hui Wang, Meng Lian, Yatao Bao, Yanyan Zhang, Zhiwei Xu

Journal: Lupus

PubMed ID: 35045734

Doi: 10.1177/09612033221074544

Products & Services: Catalog Peptides

A Peptide from Budding Yeast GAPDH Serves as a Promising Antifungal against Cryptococcus neoformans

Authors: Yang Zhang , Liyan Zhou , Yan Liu , Xi Zhao , Xianqiang Lian , Jie Zhang, De Zhao , Yujuan Wang , Jin Zhong , Junfeng Wang , Hongli Wang , Linqi Wang , Yu V Fu

Journal: Microbiol Spectr

PubMed ID: 35019693

Doi: 10.1128/spectrum.00826-21

Products & Services: Peptide Synthesis

Rapid and Specific Detection of Active SARS-CoV-2 With CRISPR/Cas12a

Authors: Xinyi Liu , Yanhua Li , Xin Wang , Yifan Song , Lina Wu , Benyuan Yu , Xiaodong Ma , Peixiang Ma, Ming Liu , Xingxu Huang , Xinjie Wang

Journal: Front Microbiol

PubMed ID: 35154046

Doi: 10.3389/fmicb.2021.820698

Products & Services: Gene Synthesis Custom DNA/RNA Oligos

An effective cytokine combination for ex vivo expansion of porcine muscle stem cells

Authors: Qingzi Lei, Mei Li, Guocheng Du, Jingwen Zhou, Xin Guan

Journal: Food Bioscience

Doi: 10.1016/j.fbio.2022.101571

Products & Services: Recombinant Proteins

Long-Term High-Fat Diet Consumption Depletes Glial Cells and Tyrosine Hydroxylase-Containing Neurons in the Brain of Middle-Aged Rats

Authors: Mei-Chuan Chou, Hsiang-Chun Lee, Yen-Chin Liu, Patrick Szu-Ying Yen, Ching-Kuan Liu, Chu-Huang Chen, Tzu-Han Hsieh, Shiou-Lan Chen

Journal: Cells

PubMed ID: 35053411

Doi: 10.3390/cells11020295

Products & Services: Proteins, Expression, Isolation and Analysis

Development of Peptide Targeted PLGA-PEGylated Nanoparticles Loading Licochalcone-A for Ocular Inflammation

Authors: Ruth Galindo, Elena Sánchez-López, María José Gómara, Marta Espina, Miren Ettcheto, Amanda Cano, Isabel Haro, Antoni Camins, María Luisa García

Journal: Pharmaceutics

PubMed ID: 35214019

Doi: 10.3390/pharmaceutics14020285

Products & Services: Biochemicals

Minc03328 effector gene downregulation severely affects Meloidogyne incognita parasitism in transgenic Arabidopsis thaliana

Authors: Valdeir Junio Vaz Moreira, Isabela Tristan Lourenço-Tessutti, Marcos Fernando Basso, Maria Eugênia Lisei-de-Sa, Carolina Vianna Morgante, Bruno Paes-de-Melo, Fabrício Barbosa Monteiro Arraes, Diogo Martins-de-Sa, Maria Cristina Mattar Silva, Janice de Almeida Engler, Maria Fatima Grossi-de-Sa

Journal: Planta

PubMed ID: 35050413

Doi: 10.1007/s00425-022-03823-4

Products & Services: Polyclonal Antibody Services

The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a

Authors: Luiza Mamigonian Bessa, Serafima Guseva, Aldo R Camacho-Zarco, Nicola Salvi, Damien Maurin, Laura Mariño Perez, Maiia Botova, Anas Malki, Max Nanao, Malene Ringkjøbing Jensen, Rob W H Ruigrok, Martin Blackledge

Journal: Sci Adv

PubMed ID: 35044811

Doi: 10.1126/sciadv.abm4034

Products & Services: Bacterial Expression

Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex

Authors: Sunesh Sethumadhavan, Marie Barth, Robbert M Spaapen, Carla Schmidt, Simon Trowitzsch, Robert Tampé

Journal: Sci Rep

PubMed ID: 35087068

Doi: 10.1038/s41598-022-05000-9

Products & Services: Gene Synthesis

Genome-wide characterization of Histone gene family and expression profiling during microspore development in radish (Raphanus sativus L)

Authors: Qijiao Wang, Lianxue Fan, Xiaojun Su, Jiali Ying, Liang Xu, Cui Li, Yan Wang, Liwang Liu

Journal: Gene

PubMed ID: 34990794

Doi: 10.1016/j.gene.2021.146180

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Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening

Authors: Meghan J O'Melia, Adriana Mulero-Russe, Jihoon Kim, Alyssa Pybus, Deborah DeRyckere, Levi Wood, Douglas K Graham, Edward Botchwey, Andrés J García, Susan N Thomas

Journal: Adv Mater

PubMed ID: 34989049

Doi: 10.1002/adma.202108084

Products & Services: Stable Cell Lines

Single-conformation spectroscopy of cold, protonated PG-containing peptides: switching β-turn types and formation of a sequential type II/II' double β-turn

Authors: John T Lawler, Christopher P Harrilal, Andrew F DeBlase, Edwin L Sibert, Scott A McLuckey, Timothy S Zwier

Journal: Phys Chem Chem Phys

PubMed ID: 35019911

Doi: 10.1039/d1cp04852j

Products & Services: Proteins, Expression, Isolation and Analysis

GRIM-19 is a target of mycobacterial Zn metalloprotease 1 and indispensable for NLRP3 inflammasome activation

Authors: Tomomi Kurane, Tetsuro Matsunaga, Tomoaki Ida, Kazuko Sawada, Akira Nishimura, Masayuki Fukui, Masayuki Umemura, Masaaki Nakayama, Naoya Ohara, Sohkichi Matsumoto, Takaaki Akaike, Goro Matsuzaki, Giichi Takaesu

Journal: FASEB J

PubMed ID: 34907600

Doi: 10.1096/fj.202101074RR

Products & Services: Codon Optimization

Efficacy of Convalescent Plasma to Treat Mild to Moderate COVID-19 in Kidney Transplant Patients: A Propensity Score Matching Analysis

Authors: Marina Pontello Cristelli, Dante Mário Langhi Junior, Laila Almeida Viana, Luis Gustavo Modelli de Andrade, Suelen Bianca Stopa Martins, Yasmim Cardoso Dreige, José Orlando Bordim, Helio Tedesco-Silva, José Medina-Pestana

Journal: Transplantation

PubMed ID: 34581314

Doi: 10.1097/TP.0000000000003962

Nucleic acid biomarkers to assess graft injury after liver transplantation

Authors: Elissa Bardhi, Jennifer McDaniels, Thomas Rousselle, Daniel G Maluf, Valeria R Mas

Journal: JHEP Rep

PubMed ID: 35243279

Doi: 10.1016/j.jhepr.2022.100439

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IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma

Authors: Suraya Elfrink, Martin Ter Beest, Luuk Janssen, Marijke Baltissen, Pascal Jansen, Angelique N Kenyon, Raymond Steen, Daynelys de Windt, Philipp Michael Hagemann, Corine Hess, Dick-Johan van Spronsen, Brigiet Hoevenaars, Ellen van der Spek, Zijun Y Xu-Monette, Ken H Young, Charlotte Kaffa, Sander Bervoets, Jolien van Heek, Eva Hesius, Charlotte M de Winde, Michiel Vermeulen, Michiel van den Brand, Blanca Scheijen, Annemiek van Spriel

Journal: Blood Adv

PubMed ID: 35086136

Doi: 10.1182/bloodadvances.2021004366

Products & Services: Plasmid DNA Preparation

The Role of Variants in Neurodevelopmental Diseases: Genotype-Phenotype Association

Authors: Li Shu, Neng Xiao, Jiong Qin, Qi Tian, Yanghui Zhang, Haoxian Li, Jing Liu, Qinrui Li, Weiyue Gu, Pengchao Wang, Hua Wang, Xiao Mao

Journal: Front Mol Neurosci

PubMed ID: 35095415

Doi: 10.3389/fnmol.2021.775479

Products & Services: Mammalian Expression

The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis

Authors: Jihui Zhang, Hongwei Lei, Xiu Li

Journal: Bioengineered

PubMed ID: 34965184

Doi: 10.1080/21655979.2021.2001911

Products & Services: Gene Synthesis

Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma

Authors: Huaijun Wang, Zhongqian Hu, Uday Kumar Sukumar, Rajendran Jc Bose, Arsenii Telichko, Jeremy J Dahl, Ramasamy Paulmurugan

Journal: Nanotheranostics

PubMed ID: 34976581

Doi: 10.7150/ntno.63320

Products & Services: Gene Synthesis

A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands

Authors: Micah Steffek, Elizabeth Helgason, Nataliya Popovych, Lionel Rougé, John M Bruning, Ke Sherry Li, Daniel J Burdick, Jianping Cai, Terry Crawford, Jing Xue, Willy Decurtins, Chunlin Fang, Felix Grubers, Michael J Holliday, Allyson Langley, Ann Petersen, Alexander Lee Satz, Aimin Song, Daniel Stoffler, Quentin Strebel, Jeffrey Y K Tom, Nicholas Skelton, Steven T Staben, Moreno Wichert, Melinda M Mulvihill, Erin C Dueber

Journal: Biochemistry

PubMed ID: 34985287

Doi: 10.1021/acs.biochem.1c00682

Products & Services: Gene Synthesis

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss)

Authors: Hui-Xia Yu, Yang Li, Wei-Jia Song, Hui Wang, Hao-Lin Mo, Qiao Liu, Xin-Miao Zhang, Ze-Bin Jiang, Li-Xin Wang

Journal: Fish Physiol Biochem

PubMed ID: 35098384

Doi: 10.1007/s10695-021-01033-5

Products & Services: Gene Synthesis

A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

Products & Services: Gene Synthesis

Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Authors: Siriorn P Watcharananan, Peera Jaru-Ampornpan, Suree Sahawongcharoen, Nattakan Naitook, Orawan Himananto, Anan Jongkaewwattana, Chavachol Setthaudom, Sasivimol Rattanasiri, Angsana Phuphuakrat, Ammarin Thakkinstian, Viroon Mavichak

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

K-edge anomalous SAXS for protein solution structure modeling

Authors: Karman Virk, Kento Yonezawa, Komal Choukate, Lucky Singh, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35102886

Doi: 10.1107/S205979832101247X

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High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

Products & Services: PCR Cloning and Subcloning

Antibody response following SARS-CoV-2 vaccination among patients with type 2 diabetes mellitus: A systematic review

Authors: Nanny Natalia M Soetedjo, Maria Riastuti Iryaningrum, Sherly Lawrensia, Hikmat Permana

Journal: Diabetes Metab Syndr

PubMed ID: 35104750

Doi: 10.1016/j.dsx.2022.102406

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Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection

Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang

Journal: Environ Sci Technol

PubMed ID: 35049283

Doi: 10.1021/acs.est.1c07172

Products & Services: Proteins, Expression, Isolation and Analysis

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