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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 134/1026 每页显示数量

Identification of a plant endophytic growth-promoting bacteria capable of inhibiting cadmium uptake in rice

Authors: Wei Tian, Le Li, Xiao Xiao, Huili Wu, Yulong Wang, Zhaoyang Hu, Nahmina Begum, Yiping Zou, Laiqing Lou, Ming Chang, Qingsheng Cai

Journal: J Appl Microbiol

PubMed ID: 34216530

Doi: 10.1111/jam.15201

Products & Services: Gene Synthesis

CDC42 as an epigenetic regulator of ID4 in triple-negative breast tumors

Authors: Daniela Nasif, Sebastian Real, María Roqué, María T Branham

Journal: Breast Cancer

PubMed ID: 35094293

Doi: 10.1007/s12282-022-01334-4

Products & Services: Catalog Antibody

Nanobody-based anti-CD22-chimeric antigen receptor T cell immunotherapy exhibits improved remission against B-cell acute lymphoblastic leukemia

Authors: Tingting Zhang, Tian Wang, Fengtao You, Zixuan Li, Dan Chen, Kailu Zhang, Shuaiyu Tian, Binjie Sheng, Hai Wu, Licui Jiang, Renyuxue Ma, Gangli An, Huimin Meng, Lin Yang

Journal: Transpl Immunol

PubMed ID: 35051588

Doi: 10.1016/j.trim.2022.101538

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Induction of humoral and cellular immune responses to COVID-19 mRNA and vector vaccines: A prospective cohort study in Bulgarian healthcare workers

Authors: Maria Nikolova, Yana Todorova, Radoslava Emilova, Iva Trifonova, Teodora Gladnishka, Nina Petrova-Yancheva, Tatyana Chervenyakova, Elena Dragusheva, Georgi Popov, Iva Christova

Journal: J Med Virol

PubMed ID: 34997611

Doi: 10.1002/jmv.27572

MPP1 Determines the Mobility of Flotillins and Controls the Confinement of Raft-Associated Molecules

Authors: Agnieszka Biernatowska, Karolina Wójtowicz, Tomasz Trombik, Aleksander F Sikorski, Aleksander Czogalla

Journal: Cells

PubMed ID: 35159121

Doi: 10.3390/cells11030311

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A Novel Potent Carrier for Unconventional Protein Export in

Authors: Magnus Philipp, Kai P Hussnaetter, Michèle Reindl, Kira Müntjes, Michael Feldbrügge, Kerstin Schipper

Journal: Front Cell Dev Biol

PubMed ID: 35083222

Doi: 10.3389/fcell.2021.816335

Products & Services: Proteins, Expression, Isolation and Analysis

Differential effect of deleting members of African swine fever virus multigene families 360 and 505 from the genotype II Georgia 2007/1 isolate on virus replication, virulence and induction of protection

Authors: Anusyah Rathakrishnan, Samuel Connell, Vlad Petrovan, Katy Moffat, Lynnette C Goatley, Tamara Jabbar, Pedro J Sánchez-Cordón, Ana L Reis, Linda K Dixon

Journal: J Virol

PubMed ID: 35044212

Doi: 10.1128/jvi.01899-21

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Characterization of a Cleavable Fusion of Human CYP24A1 with Adrenodoxin Reveals the Variable Role of Hydrophobics in Redox Partner Binding

Authors: Natalie Jay, Sean R Duffy, D Fernando Estrada

Journal: Biochemistry

PubMed ID: 34979083

Doi: 10.1021/acs.biochem.1c00770

Products & Services: Mammalian Expression

Blue-light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection

Authors: Shaista Naqvi, Qin He, Franziska Trusch, Huishan Qiu, Jasmine Pham, Qingguo Sun, John M Christie, Eleanor M Gilroy, Paul R J Birch

Journal: New Phytol

PubMed ID: 34923631

Doi: 10.1111/nph.17929

Products & Services: Molecular Biology Reagents

Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis

Authors: Russell J Jarrott, Emily J Furlong, Guillaume A Petit, David Drew, Jennifer L Martin, Maria A Halili

Journal: Protein Expr Purif

PubMed ID: 35026386

Doi: 10.1016/j.pep.2022.106047

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Vps501, a novel vacuolar SNX-BAR protein cooperates with the SEA complex to regulate TORC1 signaling

Authors: Shreya Goyal, Verónica A Segarra, Aaron M Stetcher, Andrew W Truman, Adam M Reitzel, Richard J Chi

Journal: Traffic

PubMed ID: 35098628

Doi: 10.1111/tra.12833

Products & Services: Mutagenesis Services

The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release

Authors: Mila M Paul, Sven Dannhäuser, Lydia Morris, Achmed Mrestani, Martha Hübsch, Jennifer Gehring, Georgios N Hatzopoulos, Martin Pauli, Genevieve M Auger, Grit Bornschein, Nicole Scholz, Dmitrij Ljaschenko, Martin Müller, Markus Sauer, Hartmut Schmidt, Robert J Kittel, Aaron DiAntonio, Ioannis Vakonakis, Manfred Heckmann, Tobias Langenhan

Journal: Brain

PubMed ID: 35022694

Doi: 10.1093/brain/awac011

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Investigation of putative antimicrobial peptides in Carassius gibel, revealing a practical approach to screening antimicrobials

Authors: Yujun Zhang, Ping Deng, Caijiao Dai, Mengke Wu, Xueqin Liu, Lijuan Li, Xiaoyi Pan, Junfa Yuan

Journal: Fish Shellfish Immunol

PubMed ID: 34990806

Doi: 10.1016/j.fsi.2021.12.050

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Sterility of Sustained-release Buprenorphine

Authors: Shraddha I Cantara, Crystal Gergye, Vanessa K Lee, Michael Huerkamp

Journal: J Am Assoc Lab Anim Sci

PubMed ID: 35082006

Doi: 10.30802/AALAS-JAALAS-21-000105

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Core-shell "loading-type" nanomaterials towards: Simultaneous imaging analysis of glutathione and microRNA

Authors: Lin-Lin Lu, Qin Zhang, Yu Gu, Xiang-Ling Li, Jing Jing Xie

Journal: Anal Chim Acta

PubMed ID: 35151402

Doi: 10.1016/j.aca.2022.339551

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Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses

Authors: Bo Wang, Shuang Li, Yongbo Qiao, Yu Fu, Jiaojiao Nie, Shun Jiang, Xin Yao, Yi Pan, Linye Zhao, Congmei Wu, Yuhua Shi, Yuhe Yin, Yaming Shan

Journal: J Nanobiotechnology

PubMed ID: 35012571

Doi: 10.1186/s12951-021-01229-0

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Crystal structure of the plant feruloyl-coenzyme A monolignol transferase provides insights into the formation of monolignol ferulate conjugates

Authors: Xi Liu, Shuliu Dai, Yu Zhou, Jinyue Liu, Dong Li, Jun Zhang, Yushan Zhu, Qiao Zhao, Yue Feng, Yi Zhang

Journal: Biochem Biophys Res Commun

PubMed ID: 35066379

Doi: 10.1016/j.bbrc.2022.01.037

Products & Services: Proteins, Expression, Isolation and Analysis

Crystal structure of the plant feruloyl-coenzyme A monolignol transferase provides insights into the formation of monolignol ferulate conjugates

Authors: Xi Liu, Shuliu Dai, Yu Zhou, Jinyue Liu, Dong Li, Jun Zhang, Yushan Zhu, Qiao Zhao, Yue Feng, Yi Zhang

Journal: Biochem Biophys Res Commun

PubMed ID: 35066379

Doi: 10.1016/j.bbrc.2022.01.037

Products & Services: Proteins, Expression, Isolation and Analysis

Preparation and characterization of 2-deacetyl-3-O-sulfo-heparosan and its antitumor effects via the fibroblast growth factor receptor pathway

Authors: Zhengqi Zha, Yaoyao Liu, Yinghua Miao, Shiying Liao, Su-Yan Wang, Huiling Tang, Hongping Yin

Journal: Int J Biol Macromol

PubMed ID: 34998873

Doi: 10.1016/j.ijbiomac.2021.12.098

Products & Services: Plasmid DNA Preparation

Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

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Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

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Bio-nanocapsules for oriented immobilization of DNA aptamers on aptasensors

Authors: Masumi Iijima, Yuki Yamada, Hideo Nakano, Tsutomu Nakayama, Shun'ichi Kuroda

Journal: Analyst

PubMed ID: 35023508

Doi: 10.1039/d1an02278d

Products & Services: GenParts™ DNA Fragments

Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test

Authors: Qiao Wang, Lili Feng, Haohai Zhang, Juehua Gao, Changchuin Mao, Esther Landesman-Bollag, Gustavo Mostoslavsky, Justin M Lunderberg, Weina Zheng, Shushun Hao, Wenda Gao

Journal: Antib Ther

PubMed ID: 35146332

Doi: 10.1093/abt/tbac004

Products & Services: Proteins, Expression, Isolation and Analysis

Degradation of dimethachlon by a newly isolated bacterium Paenarthrobacter sp strain JH-1 relieves its toxicity against Chlorella ellipsoidea

Authors: Mingliang Zhang, Wankui Jiang, Siyuan Gao, Qian Zhu, Zhijian Ke, Mingli Jiang, Jiguo Qiu, Qing Hong

Journal: Environ Res

PubMed ID: 35031339

Doi: 10.1016/j.envres.2022.112706

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Circ_HECTD1 regulates cerebral ischemia injury via mechanisms involving the regulation of let-7c-5p/ROCK1 axis

Authors: Qian Guo, Tingting Guo, Yuanyuan Sun, Tianrong Chen

Journal: Neuroreport

PubMed ID: 34874325

Doi: 10.1097/WNR.0000000000001743

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Involvement of β-cyanoalanine synthase (β-CAS) and sulfurtransferase (ST) in cyanide (CN) assimilation in rice seedlings

Authors: Yu-Xi Feng, Cheng-Zhi Li, Yu-Juan Lin, Xiao-Zhang Yu

Journal: Chemosphere

PubMed ID: 35101430

Doi: 10.1016/j.chemosphere.2022.133789

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Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Filamin C, Scy p 9

Authors: Xin-Rong He, Yang Yang, Shuai Kang, Ye-Xin Chen, Pei-Yi Zheng, Gui-Xia Chen, Xiao-Mei Chen, Min-Jie Cao, Tengchuan Jin, Guang-Ming Liu

Journal: J Agric Food Chem

PubMed ID: 35040643

Doi: 10.1021/acs.jafc.1c07922

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Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

Products & Services: Proteins, Expression, Isolation and Analysis

Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

Products & Services: Proteins, Expression, Isolation and Analysis

Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

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Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

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Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence

Authors: Stefano Perni, Kurt Beam

Journal: J Gen Physiol

PubMed ID: 35089322

Doi: 10.1085/jgp.202113024

Products & Services: Mammalian Expression

CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34981767

Doi: 10.1107/S205979832101216X

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Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia

Authors: Stefan Hirschberg, Anton Dvorzhak, Seyed M A Rasooli-Nejad, Svilen Angelov, Marieluise Kirchner, Philipp Mertins, Gilla Lättig-Tünnemann, Christoph Harms, Dietmar Schmitz, Rosemarie Grantyn

Journal: Front Cell Neurosci

PubMed ID: 35173582

Doi: 10.3389/fncel.2021.792652

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Journal: Front Cell Neurosci

PubMed ID: 35173582

Doi: 10.3389/fncel.2021.792652

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DNA methylation analysis of ELOVL2 gene using droplet digital PCR for age estimation purposes

Authors: Licínio Manco, Helena Correia Dias

Journal: FORENSIC SCI INT

PubMed ID: 35131731

Doi: 10.1016/j.forsciint.2022.111206

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DNA methylation analysis of ELOVL2 gene using droplet digital PCR for age estimation purposes

Authors: Licínio Manco, Helena Correia Dias

Journal: FORENSIC SCI INT

PubMed ID: 35131731

Doi: 10.1016/j.forsciint.2022.111206

Products & Services: Custom DNA/RNA Oligos

CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34981767

Doi: 10.1107/S205979832101216X

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Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin

Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng

Journal: Pharmaceutics

PubMed ID: 35057038

Doi: 10.3390/pharmaceutics14010144

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Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin

Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng

Journal: Pharmaceutics

PubMed ID: 35057038

Doi: 10.3390/pharmaceutics14010144

Products & Services: Plasmid DNA Preparation

Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection

Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang

Journal: Environ Sci Technol

PubMed ID: 35049283

Doi: 10.1021/acs.est.1c07172

Products & Services: Proteins, Expression, Isolation and Analysis

Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

Authors: Nathaniel L Miller, Thomas Clark, Rahul Raman, Ram Sasisekharan

Journal: Cell Rep Med

PubMed ID: 35233548

Doi: 10.1016/j.xcrm.2022.100527

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Conditional Alternative Protein Splicing Promoted by Inteins from

Authors: Vaishnavi R Yalala, Abigeal K Lynch, Kenneth V Mills

Journal: Biochemistry

PubMed ID: 35073064

Doi: 10.1021/acs.biochem.1c00788

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Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

Authors: Nathaniel L Miller, Thomas Clark, Rahul Raman, Ram Sasisekharan

Journal: Cell Rep Med

PubMed ID: 35233548

Doi: 10.1016/j.xcrm.2022.100527

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Genome-wide identification and expression profile of YABBY genes in

Authors: Chengru Li, Na Dong, Liming Shen, Meng Lu, Junwen Zhai, Yamei Zhao, Lei Chen, Zhiting Wan, Zhongjian Liu, Hui Ren, Shasha Wu

Journal: PeerJ

PubMed ID: 35036123

Doi: 10.7717/peerj.12558

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Production and application of mouse monoclonal antibodies targeting linear epitopes in pB602L of African swine fever virus

Authors: Pengfei Wang, Chunguo Liu, Shida Wang, Lili Wen, Zhibin Shi, Yue Chi, Ming Wang, Zaisi Liu, Zhenzhao Sun, Lili Wei, Decheng Yang, Xijun He, Jingfei Wang

Journal: Arch Virol

PubMed ID: 34984562

Doi: 10.1007/s00705-021-05335-0

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Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia

Authors: Fangyi Yao, Cui Zhao, Fangmin Zhong, Tingyu Qin, Shuqi Li, Jing Liu, Bo Huang, Xiaozhong Wang

Journal: PeerJ

PubMed ID: 35111390

Doi: 10.7717/peerj.12616

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Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia

Authors: Fangyi Yao, Cui Zhao, Fangmin Zhong, Tingyu Qin, Shuqi Li, Jing Liu, Bo Huang, Xiaozhong Wang

Journal: PeerJ

PubMed ID: 35111390

Doi: 10.7717/peerj.12616

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The Novel microRNA Rno-miR-686-3p Is Associated with the Ischaemic Penumbra

Authors: Wei Wang, Jin-Pin Li, Jing-Li Liu

Journal: Eur Neurol

PubMed ID: 35100587

Doi: 10.1159/000521491

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Self-Assembly of Flagellin into Immunostimulatory Ring-like Nanostructures as an Antigen Delivery System

Authors: Mélanie Côté-Cyr, Ximena Zottig, Laurie Gauthier, Denis Archambault, Steve Bourgault

Journal: ACS Biomater Sci Eng

PubMed ID: 35080372

Doi: 10.1021/acsbiomaterials.1c01332

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