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Role of PG0192 and PG0193 in the modulation of pro-inflammatory cytokines in macrophages in response to Porphyromonas gingivalis

Authors: Hongyan Wang, Wenying Peng, Guangyu Zhang, Muzhou Jiang, Jian Zhao, Xue Zhao, Yaping Pan, Li Lin

Journal: Eur J Oral Sci

PubMed ID: 35049069

Doi: 10.1111/eos.12851

Products & Services: GenParts™ DNA Fragments

Role of PG0192 and PG0193 in the modulation of pro-inflammatory cytokines in macrophages in response to Porphyromonas gingivalis

Authors: Hongyan Wang, Wenying Peng, Guangyu Zhang, Muzhou Jiang, Jian Zhao, Xue Zhao, Yaping Pan, Li Lin

Journal: Eur J Oral Sci

PubMed ID: 35049069

Doi: 10.1111/eos.12851

Products & Services: GenParts™ DNA Fragments

Protocol for structure determination of SARS-CoV-2 main protease at near-physiological-temperature by serial femtosecond crystallography

Authors: Fatma Betul Ertem, Omur Guven, Cengizhan Buyukdag, Oktay Gocenler, Esra Ayan, Busra Yuksel, Mehmet Gul, Gozde Usta, Barıs Cakılkaya, J Austin Johnson, E Han Dao, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Brandon Hayes, Mengning Liang, Mark S Hunter, Alexander Batyuk, Raymond G Sierra, Gihan Ketawala, Sabine Botha, Çağdaş Dağ, Hasan DeMirci

Journal: STAR Protoc

PubMed ID: 35194584

Doi: 10.1016/j.xpro.2022.101158

Products & Services: Proteins, Expression, Isolation and Analysis

Large inter-individual variability of cellular and humoral immunological responses to mRNA-1273 (Moderna) vaccination against SARS-CoV-2 in health care workers

Authors: Alexander Krüttgen, Gerhard Haase, Helga Haefner, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223670

Doi: 10.7774/cevr.2022.11.1.96

CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA

Authors: Simin Chen, Zhaoyu Zhang, Baoxin Zhang, Qing Huang, Yi Liu, Yi Qiu, Xinmiao Long, Minghua Wu, Zuping Zhang

Journal: Int J Biol Sci

PubMed ID: 35002529

Doi: 10.7150/ijbs.66114

Products & Services: Plasmid DNA Preparation

Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue

Authors: Yingzi Tan, Miao Wang, Yijun Chen

Journal: ACS Synth Biol

PubMed ID: 35006674

Doi: 10.1021/acssynbio.1c00578

Products & Services: Gene Synthesis

The Linker Region Promotes Activity and Binding Efficiency of Modular LPMO towards Polymeric Substrate

Authors: Aishwarya Srivastava, Pragya Nagar, Sumit Rathore, Nidhi Adlakha

Journal: Microbiol Spectr

PubMed ID: 35080440

Doi: 10.1128/spectrum.02697-21

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Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites

Authors: Bruna Felício Milazzotto Maldonado Porchia, Luana Raposo de Melo Moraes Aps, Ana Carolina Ramos Moreno, Jamile Ramos da Silva, Mariângela de Oliveira Silva, Natiely Silva Sales, Rubens Prince Dos Santos Alves, Clarissa Ribeiro Reily Rocha, Matheus Molina Silva, Karine Bitencourt Rodrigues, Tácita Borges Barros, Roberta Liberato Pagni, Patrícia da Cruz Souza, Mariana de Oliveira Diniz, Luís Carlos de Souza Ferreira

Journal: Int J Biol Sci

PubMed ID: 34975315

Doi: 10.7150/ijbs.56644

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Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin

Authors: Favian A Liu, Negar Ardabili, Izaiah Brown, Harmain Rafi, Clarice Cook, Rodanthi Nikopoulou, Arianna Lopez, Shouzhong Zou, Matthew R Hartings, Alexander G Zestos

Journal: J Electrochem Soc

PubMed ID: 35185166

Doi: 10.1149/1945-7111/ac4aae

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An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein

Authors: Yahiro Mukai, Masayuki Horie, Shohei Kojima, Junna Kawasaki, Ken Maeda, Keizo Tomonaga

Journal: FEBS Lett

PubMed ID: 35043395

Doi: 10.1002/1873-3468.14290

Products & Services: Recombinant Antibody Expression

Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway

Authors: Veronica Mutti, Federica Bono, Zaira Tomasoni, Leonardo Bontempi, Adele Guglielmi, Silvia Bolognin, Jens C Schwamborn, Cristina Missale, Chiara Fiorentini

Journal: Mol Neurobiol

PubMed ID: 35044626

Doi: 10.1007/s12035-022-02748-z

Products & Services: Gene Synthesis

miR-541-3p Promoted Porcine Reproductive and Respiratory Syndrome Virus 2 (PRRSV-2) Replication by Targeting Interferon Regulatory Factor 7

Authors: Xibao Shi, Yuanhao Yang, Xiaozhuan Zhang, Xiaobo Chang, Jing Chen, Chao Wang, Aiping Wang, Jianhua Wang, Jianru Qin, Xianlong Ye, Wei Jin, Gaiping Zhang

Journal: Viruses

PubMed ID: 35062330

Doi: 10.3390/v14010126

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Expression of phenylalanine ammonia lyases in Synechocystis sp PCC 6803 and subsequent improvements of sustainable production of phenylpropanoids

Authors: Kateryna Kukil, Pia Lindberg

Journal: Microb Cell Fact

PubMed ID: 35012528

Doi: 10.1186/s12934-021-01735-8

Products & Services: Codon Optimization

Targeted deletion of liver-expressed Choriogenin L results in the production of soft eggs and infertility in medaka, Oryzias latipes

Authors: Kenji Murata, Masato Kinoshita

Journal: Zoological Lett

PubMed ID: 34983666

Doi: 10.1186/s40851-021-00185-9

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Anion binding to a cationic europium(III) probe enables the first real-time assay of heparan sulfotransferase activity

Authors: Simon Wheeler, Colum Breen, Yong Li, Sarah H Hewitt, Erin Robertson, Edwin A Yates, Igor L Barsukov, David G Fernig, Stephen J Butler

Journal: Org Biomol Chem

PubMed ID: 34951618

Doi: 10.1039/d1ob02071d

Products & Services: Proteins, Expression, Isolation and Analysis

Multiplex genome editing of mammalian cells for producing recombinant heparin

Authors: Bryan E Thacker, Kristen J Thorne, Colin Cartwright, Jeeyoung Park, Kimberly Glass, Annie Chea, Benjamin P Kellman, Nathan E Lewis, Zhenping Wang, Anna Di Nardo, Susan T Sharfstein, Walter Jeske, Jeanine Walenga, John Hogwood, Elaine Gray, Barbara Mulloy, Jeffrey D Esko, Charles A Glass

Journal: Metab Eng

PubMed ID: 35038554

Doi: 10.1016/j.ymben.2022.01.002

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Multiplex genome editing of mammalian cells for producing recombinant heparin

Journal: Metab Eng

PubMed ID: 35038554

Doi: 10.1016/j.ymben.2022.01.002

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Genome-wide analysis and transcriptional reprogrammings of MYB superfamily revealed positive insights into abiotic stress responses and anthocyanin accumulation in Carthamus tinctorius L

Authors: Yingqi Hong, Naveed Ahmad, Jianyi Zhang, Yanxi Lv, Xinyue Zhang, Xintong Ma, Liu Xiuming, Yao Na

Journal: Mol Genet Genomics

PubMed ID: 34978004

Doi: 10.1007/s00438-021-01839-1

Products & Services: Protein Tools

Knockdown of DPP4 promotes the proliferation and the activation of the CREB/aromatase pathway in ovarian granulosa cells

Authors: Lina Lin, Liman Wang

Journal: Mol Med Rep

PubMed ID: 35014677

Doi: 10.3892/mmr.2022.12589

Products & Services: Gene Synthesis

Highly efficient A-to-G base editing by ABE8.17 in rabbits

Authors: Ding Zhao , Yuqiang Qian , Jinze Li , Zhanjun Li , Liangxue Lai

Journal: Mol Ther Nucleic Acids .

PubMed ID: 35282412

Doi: 10.1016/j.omtn.2022.01.019

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Optimization of Protoplast Isolation and Transformation for a Pilot Study of Genome Editing in Peanut by Targeting the Allergen Gene

Authors: Sudip Biswas, Nancy J Wahl, Michael J Thomson, John M Cason, Bill F McCutchen, Endang M Septiningsih

Journal: Int J Mol Sci

PubMed ID: 35055026

Doi: 10.3390/ijms23020837

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Performance of the cobas® HBV RNA automated investigational assay for the detection and quantification of circulating HBV RNA in chronic HBV patients

Authors: Caroline Scholtès, Aaron T Hamilton, Marie-Laure Plissonnier, Caroline Charre, Beth Scott, Ling Wang, Françoise Berby, Janine French, Barbara Testoni, Alan Blair, Miroslava Subic, Matthias Hoppler, Andreas Lankenau, Andreas Grubenmann, Massimo Levrero, Marintha L Heil, Fabien Zoulim

Journal: J Clin Virol

PubMed ID: 35427860

Doi: 10.1016/j.jcv.2022.105150

Products & Services: Molecular Biology Reagents

Reactivity of DENV-positive sera against recombinant envelope proteins produced in bacteria and eukaryotic cells

Authors: Higo Fernando Santos Souza, Arthur Baruel Zaneti, Bianca da Silva Almeida, Jéssica Amaral Martinho, Márcio Massao Yamamoto, Daniela Santoro Rosa, Renata Denzegrini Slhessarenko, Silvia Beatriz Boscardin

Journal: Immunol Res

PubMed ID: 36192522

Doi: 10.1007/s12026-022-09326-4

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered bacterial host for genetic encoding of physiologically stable protein nitration

Authors: Nikolaj G Koch, Tobias Baumann, Jessica H Nickling, Anna Dziegielewski, Nediljko Budisa

Journal: Front Mol Biosci

PubMed ID: 36353730

Doi: 10.3389/fmolb.2022.992748

Products & Services: Gene Synthesis

Intra-amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses

Authors: Xiaowei Wei, Wei Ma, Hui Gu, Dan Liu, Wenting Luo, Songying Cao, Shanshan Jia, Tianchu Huang, Yiwen He, Yuzuo Bai, Weilin Wang, Zhengwei Yuan

Journal: Cell Prolif

PubMed ID: 36266504

Doi: 10.1111/cpr.13354

Products & Services: Gene Synthesis

Tongxinluo prevents chronic obstructive pulmonary disease complicated with atherosclerosis by inhibiting ferroptosis and protecting against pulmonary microvascular barrier dysfunction

Authors: Yafen Wang, Xiangnan Kuang, Yujie Yin , Ningxin Han, Liping Chang, Hongtao Wang, Yunlong Hou, Huixin Li, Zhen Li , Yi Liu, Yuanjie Hao , Yaru Wei, Xiaoqi Wang, Zhenhua Jia

Journal: Biomed Pharmacother

PubMed ID: 34740097

Doi: 10.1016/j.biopha.2021.112367

Products & Services: Proteins, Expression, Isolation and Analysis

CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy

Authors: Dan Wang, Ling Chen, Chengbi Li, Quanxin Long, Qing Yang, Ailong Huang, Hua Tang

Journal: J Nanobiotechnology

PubMed ID: 34991617

Doi: 10.1186/s12951-021-01233-4

Products & Services: GenCrispr Cas9 Genome Editing

Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase

Authors: Chia Wei Hsu, Mark L Sowers, Tuvshintugs Baljinnyam, Jason L Herring, Linda C Hackfeld, Hui Tang, Kangling Zhang, Lawrence C Sowers

Journal: J Biol Chem

PubMed ID: 35085553

Doi: 10.1016/j.jbc.2022.101638

Products & Services: Gene Synthesis

Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection

Authors: Bojie Xu , Ruicheng Yang , Bo Yang , Liang Li , Jiaqi Chen , Jiyang Fu , Xinyi Qu , Dong Huo , Chen Tan , Huanchun Chen , Zhong Peng , Xiangru Wang

Journal: Mol Brain

PubMed ID: 34980188

Doi: 10.1186/s13041-021-00890-8

Products & Services: ORF cDNA Clones/MolecularCloud

SARS-CoV-2 S Protein Subunit 1 Elicits Ca2+ Influx – Dependent Ca2+ Signals in Pancreatic Stellate Cells and Macrophages In Situ

Authors: Julia V Gerasimenko , Ole H Petersen , Oleg V Gerasimenko

Journal: Function (Oxf)

Doi: 10.1093/function/zqac002

Products & Services: Recombinant Proteins

Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus

Authors: Bryce P Johnson , Vikas Kumar , Erin M Scull , Leonard M Thomas , Christina R Bourne , Shanteri Singh

Journal: ACS Chem Biol

PubMed ID: 34905349

Doi: 10.1021/acschembio.1c00655

Products & Services: Gene Synthesis

Efficient Amber Suppression Ribosomal Skipping for Synthesis of Photoconditional Nanobodies

Authors: Eike F Joest, Christian Winter, Joshua S Wesalo, Alexander Deiters, Robert Tampé

Journal: ACS Synth Biol

PubMed ID: 35060375

Doi: 10.1021/acssynbio.1c00471

Products & Services: Plasmid DNA Preparation

Protein Phosphatase 2A Deficiency in Macrophages Increases Foam Cell Formation and Accelerates Atherosclerotic Lesion Development

Authors: Rui Li, Chao Zhang, Fei Xie, Xianming Zhou, Xingjian Hu, Jiawei Shi, Xinling Du, Zhiyong Lin, Nianguo Dong

Journal: Front Cardiovasc Med

PubMed ID: 35118139

Doi: 10.3389/fcvm.2021.745009

Products & Services: Proteins, Expression, Isolation and Analysis

Synthesis of broad-specificity activity-based probes for -β-mannosidases

Authors: Nicholas G S McGregor, Chi-Lin Kuo, Thomas J M Beenakker, Chun-Sing Wong, Wendy A Offen, Zachary Armstrong, Bogdan I Florea, Jeroen D C Codée, Herman S Overkleeft, Johannes M F G Aerts, Gideon J Davies

Journal: Org Biomol Chem

PubMed ID: 35015006

Doi: 10.1039/d1ob02287c

Products & Services: Proteins, Expression, Isolation and Analysis

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system

Authors: Yue Wu, Zhenling Cui, Yen-Hua Huang, Simon J de Veer, Andrey V Aralov, Zhong Guo, Shayli V Moradi, Alexandra O Hinton, Jennifer R Deuis, Shaodong Guo, Kai-En Chen, Brett M Collins, Irina Vetter, Volker Herzig, Alun Jones, Matthew A Cooper, Glenn F King, David J Craik, Kirill Alexandrov, Sergey Mureev

Journal: Nat Commun

PubMed ID: 35017494

Doi: 10.1038/s41467-021-27854-9

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Dietary Isoflavones Alter Gut Microbiota and Lipopolysaccharide Biosynthesis to Reduce Inflammation

Authors: Sudeep Ghimire, Nicole M Cady, Peter Lehman, Stephanie R Peterson, Shailesh K Shahi, Faraz Rashid, Shailendra Giri, Ashutosh K Mangalam

Journal: Gut Microbes

PubMed ID: 36179318

Doi: 10.1080/19490976.2022.2127446

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Identification of sequence-specific promoters driving polycistronic transcription initiation by RNA polymerase II in trypanosomes

Authors: Carlos Cordon-Obras, Claudia Gomez-Liñan, Sara Torres-Rusillo, Isabel Vidal-Cobo, Diana Lopez-Farfan, Alicia Barroso-Del Jesus, Domingo Rojas-Barros, Mark Carrington, Miguel Navarro

Journal: Cell Rep

PubMed ID: 35021094

Doi: 10.1016/j.celrep.2021.110221

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FACI Is a Novel CREB-H-Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity

Authors: Yun Cheng, Xiao-Zhuo Kang, Tao Cheng, Zi-Wei Ye, George L Tipoe, Cheng-Han Yu, Chi-Ming Wong, Baohua Liu, Chi-Ping Chan, Dong-Yan Jin

Journal: Cell Mol Gastroenterol Hepatol

PubMed ID: 35093589

Doi: 10.1016/j.jcmgh.2022.01.017

Products & Services: Stable Cell Lines

The Impact of Tyrosine Iodination on the Aggregation and Cleavage Kinetics of MMP-9-Responsive Peptide Sequences

Authors: Douglas S MacPherson, Scott A McPhee, Brian M Zeglis, Rein V Ulijn

Journal: ACS Biomater Sci Eng

PubMed ID: 35050574

Doi: 10.1021/acsbiomaterials.1c01488

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Novel Neutralizing Epitope of PEDV S1 Protein Identified by IgM Monoclonal Antibody

Authors: Techit Thavorasak, Monrat Chulanetra, Kittirat Glab-Ampai, Karsidete Teeranitayatarn, Thaweesak Songserm, Rungrueang Yodsheewan, Nawannaporn Sae-Lim, Porntippa Lekcharoensuk, Nitat Sookrung, Wanpen Chaicumpa

Journal: Viruses

PubMed ID: 35062329

Doi: 10.3390/v14010125

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Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

Authors: Hyo Jung Sim, Chanmi Cho, Ha Eun Kim, Ju Yeon Hong, Eun Kyung Song, Keun Yeong Kwon, Dong Gil Jang, Seok-Jung Kim, Hyun-Shik Lee, Changwook Lee, Taejoon Kwon, Siyoung Yang, Tae Joo Park

Journal: Sci Adv

PubMed ID: 35061535

Doi: 10.1126/sciadv.abl4222

Products & Services: Recombinant Antibody Expression

Cytokines in the Immune Microenvironment Change the Glycosylation of IgG by Regulating Intracellular Glycosyltransferases

Authors: Yedi Cao, Zhijing Song, Zhendong Guo, Xue Zhao, Yan Gong, Keli Zhao, Chenxue Qu, Youyuan Huang, Yan Li, Ying Gao, Junqing Zhang, Xiaohui Guo

Journal: Front Immunol

PubMed ID: 35140700

Doi: 10.3389/fimmu.2021.724379

Products & Services: Proteins, Expression, Isolation and Analysis

Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment

Authors: Le Thi My Le, James Robert Thompson, Phuoc Xuan Dang, Janarjan Bhandari, Amer Alam

Journal: Commun Biol

PubMed ID: 35013584

Doi: 10.1038/s42003-021-02970-w

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Shoc2 recognizes bacterial flagellin and mediates antibacterial Erk/Stat signaling in an invertebrate

Authors: Bao-Rui Zhao, Xin-Xin Wang, Xian-Wei Wang

Journal: PLoS Pathog

PubMed ID: 35073369

Doi: 10.1371/journal.ppat.1010253

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered human antibodies for the opsonization and killing of

Authors: Xinhai Chen, Olaf Schneewind, Dominique Missiakas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35058363

Doi: 10.1073/pnas.2114478119

Products & Services: Proteins, Expression, Isolation and Analysis

Porcine TRIM21 Enhances Porcine Circovirus 2 Infection and Host Immune Responses, But Inhibits Apoptosis of PCV2-Infected Cells

Authors: Lin Yang, Xiaohua Liu, Liying Zhang, Xue Li, Xinwei Zhang, Guoyu Niu, Weilong Ji, Si Chen, Hongsheng Ouyang, Linzhu Ren

Journal: Viruses

PubMed ID: 35062360

Doi: 10.3390/v14010156

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Targeted gene silencing in the nervous system with CRISPR-Cas13

Authors: Jackson E Powell, Colin K W Lim, Ramya Krishnan, Tristan X McCallister, Christian Saporito-Magriña, Maria A Zeballos, Garrett D McPheron, Thomas Gaj

Journal: Sci Adv

PubMed ID: 35044815

Doi: 10.1126/sciadv.abk2485

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Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus

Authors: Liqi Liu, Zi Li, Jianfang Zhou, Jia Liu, Xiyan Li, Weijuan Huang, Ning Xiao, Dayan Wang

Journal: Influenza Other Respir Viruses

PubMed ID: 35037399

Doi: 10.1111/irv.12954

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Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer

Authors: Junko Matsuzaki, Shashikant Lele, Kunle Odunsi, Takemasa Tsuji

Journal: Oncoimmunology

PubMed ID: 35003898

Doi: 10.1080/2162402X.2021.2020983

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Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer

Authors: Junko Matsuzaki, Shashikant Lele, Kunle Odunsi, Takemasa Tsuji

Journal: Oncoimmunology

PubMed ID: 35003898

Doi: 10.1080/2162402X.2021.2020983

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