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Architecture of the chloroplast PSI-NDH supercomplex in Hordeum vulgare

Authors: Liangliang Shen, Kailu Tang, Wenda Wang, Chen Wang, Hangjun Wu, Zhiyuan Mao, Shaoya An, Shenghai Chang, Tingyun Kuang, Jian-Ren Shen, Guangye Han, Xing Zhang

Journal: Nature

PubMed ID: 34879391

Doi: 10.1038/s41586-021-04277-6

Products & Services: Peptide Synthesis

Chromosome-specific painting unveils chromosomal fusions and distinct allopolyploid species in the Saccharum complex

Authors: Fan Yu, Xinwang Zhao, Jin Chai, Xueer Ding, Xueting Li, Yongji Huang, Xianhong Wang, Jiayun Wu, Muqing Zhang, Qinghui Yang, Zuhu Deng, Jiming Jiang

Journal: New Phytol

PubMed ID: 34874076

Doi: 10.1111/nph.17905

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Ndufa6 regulates adipogenic differentiation via Scd1

Authors: Jingwei Zhang, Wei Wang, Ninghan Feng, Xuan Jiang, Shenglong Zhu, Yong Q Chen

Journal: Adipocyte

PubMed ID: 34793269

Doi: 10.1080/21623945.2021.2007590

Products & Services: Recombinant Proteins

Circular RNA erythrocyte membrane protein band 41 assuages ultraviolet irradiation-induced apoptosis of lens epithelial cells by stimulating 5'-bisphosphate nucleotidase 1 in a miR-24-3p-dependent manner

Authors: Cuiyun Zhou, Xiaoqiong Huang, Xia Li, Yan Xiong

Journal: Bioengineered

PubMed ID: 34652259

Doi: 10.1080/21655979.2021.1990196

Products & Services: Proteins, Expression, Isolation and Analysis

Transcription factor specificity protein 1-mediated Serine/threonine kinase 39 upregulation promotes the proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells by activating the transforming growth factor-β1 /Smad2/3 pathway

Authors: Jing Wang, Zhenyu Fan, Jia Li, Jingmao Yang, Xiaofei Liu, Jilin Cheng

Journal: Bioengineered

PubMed ID: 34281492

Doi: 10.1080/21655979.2021.1947939

Products & Services: Proteins, Expression, Isolation and Analysis

Correction to: Expanding the Genetic and Phenotypic Spectrum of Female Infertility Caused by TUBB8 Mutations

Authors: Qianneng Lu, Xiaolan Zhang, Qiqi Cao, Congjing Wang, Jie Ding, Chun Zhao, Junqiang Zhang, Xiufeng Ling, Qingxia Meng, Ran Huo, Hong Li

Journal: Reprod Sci

PubMed ID: 34542892

Doi: 10.1007/s43032-021-00742-9

Products & Services: DNA Sequencing

Melatonin protects H9c2 cardiomyoblasts from oxygen glucose deprivation and reperfusion-induced injury by inhibiting Rac1/JNK/Foxo3a/Bim signaling pathway

Authors: Yulin Wang, Ying Jian, Xiaofu Zhang, Bin Ni, Mingwei Wang, Chunqi Pan

Journal: Cell Biol Int

PubMed ID: 34882903

Doi: 10.1002/cbin.11739

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Enhancing the detection sensitivity of nanobody against aflatoxin B through structure-guided modification

Authors: Ting He, Yao Nie, Tingting Yan, Jiang Zhu, Xiaoling He, Ying Li, Qi Zhang, Xiaoqian Tang, Rui Hu, Yunhuang Yang, Maili Liu

Journal: Int J Biol Macromol

PubMed ID: 34863829

Doi: 10.1016/j.ijbiomac.2021.11.182

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Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials

Authors: Gang Zeng, Qianhui Wu, Hongxing Pan, Minjie Li, Juan Yang, Lin Wang, Zhiwei Wu, Deyu Jiang, Xiaowei Deng, Kai Chu, Wen Zheng, Lei Wang, Wanying Lu, Bihua Han, Yuliang Zhao, Fengcai Zhu, Hongjie Yu, Weidong Yin

Journal: Lancet Infect Dis

PubMed ID: 34890537

Doi: 10.1016/S1473-3099(21)00681-2

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A new self-attenuated therapeutic influenza vaccine that uses host cell-restricted attenuation by artificial microRNAs

Authors: Ke Wen, Haiyan Wang, Yanping Chen, Huixiao Yang, Zhichao Zheng, Yongyong Yan, Realivazquez Adilene, Mingtao Zeng

Journal: Int J Pharm

PubMed ID: 34883209

Doi: 10.1016/j.ijpharm.2021.121325

Products & Services: Gene Synthesis

Low-dose cyclooxygenase-2 (COX-2) inhibitor celecoxib plays a protective role in the rat model of neonatal necrotizing enterocolitis

Authors:

Journal: Bioengineered

PubMed ID: 34546832

Doi: 10.1080/21655979.2021.1980646

Products & Services: Custom DNA/RNA Oligos

4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase

Authors: Emma G Jackson, Giuliano Cutolo, Bo Yang, Nageswari Yarravarapu, Mary W N Burns, Ganka Bineva-Todd, Chloë Roustan, James B Thoden, Halley M Lin-Jones, Toin H van Kuppevelt, Hazel M Holden, Benjamin Schumann, Jennifer J Kohler, Christina M Woo, Matthew R Pratt

Journal: ACS Chem Biol

PubMed ID: 34931806

Doi: 10.1021/acschembio.1c00818

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SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells

Authors: Jinliang Wang, Guan Yang, Xinxin Wang, Zhiyuan Wen, Lei Shuai, Jie Luo, Chong Wang, Ziruo Sun, Renqiang Liu, Jinying Ge, Xijun He, Ronghong Hua, Xijun Wang, Xiao Yang, Weiye Chen, Gongxun Zhong, Zhigao Bu

Journal: Cell Discov

PubMed ID: 34903715

Doi: 10.1038/s41421-021-00357-z

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Novel pentose-regulated promoter of with application in controlling heterologous gene expression

Authors: Sukanya Jeennor, Jutamas Anantayanon, Chanikul Chutrakul, Sarocha Panchanawaporn, Kobkul Laoteng

Journal: Biotechnol Rep (Amst)

PubMed ID: 35004236

Doi: 10.1016/j.btre.2021.e00695

Products & Services: Gene Synthesis

A vesicular stomatitis virus-based prime-boost vaccination strategy induces potent and protective neutralizing antibodies against SARS-CoV-2

Authors: Gyoung Nyoun Kim, Jung-Ah Choi, Kunyu Wu, Nasrin Saeedian, Eunji Yang, Hayan Park, Sun-Je Woo, Gippeum Lim, Seong-Gyu Kim, Su-Kyeong Eo, Hoe Won Jeong, Taewoo Kim, Jae-Hyung Chang, Sang Hwan Seo, Na Hyung Kim, Eunsil Choi, Seungho Choo, Sangkyun Lee, Andrew Winterborn, Yue Li, Kate Parham, Justin M Donovan, Brock Fenton, Jimmy D Dikeakos, Gregory A Dekaban, S M Mansour Haeryfar, Ryan M Troyer, Eric J Arts, Stephen D Barr, Manki Song, C Yong Kang

Journal: PLoS Pathog

PubMed ID: 34914812

Doi: 10.1371/journal.ppat.1010092

Products & Services: Mammalian Expression

Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp

Authors: Carlos Alberto-Silva, Fernanda Calheta Vieira Portaro, Roberto Tadashi Kodama, Halyne Queiroz Pantaleão, Hidetoshi Inagaki, Ken-Ichi Nihei, Katsuhiro Konno

Journal: Toxins (Basel)

PubMed ID: 34941722

Doi: 10.3390/toxins13120885

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Overproduction of medicinal ergot alkaloids based on a fungal platform

Authors: Yongpeng Yao, Wei Wang, Wenyu Shi, Rui Yan, Jun Zhang, Guangzheng Wei, Ling Liu, Yongsheng Che, Chunyan An, Shu-Shan Gao

Journal: Metab Eng

PubMed ID: 34902590

Doi: 10.1016/j.ymben.2021.12.002

Products & Services: Gene Synthesis

Developing a secretory AcGFP1-based IRES expression system for efficient production of mammalian recombinant proteins

Authors: Zhongcheng Zou, Matthew Spencer, Peter D Sun

Journal: Protein Expr Purif

PubMed ID: 34920134

Doi: 10.1016/j.pep.2021.106029

Products & Services: Codon Optimization

COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer

Authors: Cong Zeng, John P Evans, Karthik Chakravarthy, Panke Qu, Sarah Reisinger, No-Joon Song, Mark P Rubinstein, Peter G Shields, Zihai Li, Shan-Lu Liu

Journal: Cancer Cell

PubMed ID: 34986328

Doi: 10.1016/j.ccell.2021.12.014

Products & Services: PCR Cloning and Subcloning

Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro

Authors: Lin Chen, Zhi-Qiang Pan, Chang-Bin Zhai

Journal: Folia Histochem Cytobiol

PubMed ID: 34905214

Doi: 10.5603/FHC.a2021.0031

Products & Services: GenParts™ DNA Fragments

Hydroxysafflor yellow A inhibits the proliferation, migration, and invasion of colorectal cancer cells through the PPARγ/PTEN/Akt signaling pathway

Authors: Dan Su, Chunye Lv

Journal: Bioengineered

PubMed ID: 34889713

Doi: 10.1080/21655979.2021.2009965

Products & Services: Gene Synthesis

Key factors determining competitions between double-stranded RNAs in Tribolium castaneum

Authors: Xu Shen, Yingchuan Peng, Huifang Song, Jinda Wang, Jun Zhao, Peian Tang, Zhaojun Han, Kangxu Wang

Journal: Pestic Biochem Physiol

PubMed ID: 35082032

Doi: 10.1016/j.pestbp.2021.105009

Products & Services: Gene Synthesis

Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis

Authors: Yi-Ping Liu, Zhong-Zhi Qiu, Xu-Hui Li, En-You Li

Journal: World J Gastrointest Oncol

PubMed ID: 35070046

Doi: 10.4251/wjgo.v13.i12.2114

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Ultrasound treatment can increase digestibility of myofibrillar protein of pork with modified atmosphere packaging

Authors: Shuai Jiang, Miao Zhang, Hui Liu, Qian Li, Dejiang Xue, Yingqun Nian, Di Zhao, Kai Shan, Chen Dai, Chunbao Li

Journal: Food Chem

PubMed ID: 35030336

Doi: 10.1016/j.foodchem.2021.131811

Products & Services: Proteins, Expression, Isolation and Analysis

Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model

Authors: Murad Alahdal, Rongxiang Huang, Li Duan, Deng Zhiqin, Ouyang Hongwei, Wencui Li, Daping Wang

Journal: Front Immunol

PubMed ID: 34956209

Doi: 10.3389/fimmu.2021.781185

Products & Services: Proteins, Expression, Isolation and Analysis

Biomaterial-mediated presentation of wnt5a mimetic ligands enhances chondrogenesis and metabolism of stem cells by activating non-canonical Wnt signaling

Authors: Yingrui Deng, Xiaoting Zhang, Rui Li, Zhuo Li, Boguang Yang, Peng Shi, Honglu Zhang, Chunming Wang, Chunyi Wen, Gang Li, Liming Bian

Journal: Biomaterials

PubMed ID: 34959028

Doi: 10.1016/j.biomaterials.2021.121316

Products & Services: Proteins, Expression, Isolation and Analysis

The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling

Authors: Xihua Wang, Shuyuan Guan, Lingbin Sun, Zhongliang Dai

Journal: Environ Toxicol Pharmacol

PubMed ID: 34883242

Doi: 10.1016/j.etap.2021.103782

Products & Services: Proteins, Expression, Isolation and Analysis

Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

Products & Services: Peptide Synthesis

Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

Products & Services: Peptide Synthesis

Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

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Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

Products & Services: Protein Tools

An immunochromatographic assay utilizing magnetic nanoparticles to detect major peanut allergen Ara h 1 in processed foods

Authors: Hsin-Yi Yin, Yi-Ting Li, Wen-Che Tsai, Hong-Yu Dai, Hsiao-Wei Wen

Journal: Food Chem

PubMed ID: 34952385

Doi: 10.1016/j.foodchem.2021.131844

Products & Services: Peptide Synthesis

KIAA1217 Promotes Epithelial-Mesenchymal Transition and Hepatocellular Carcinoma Metastasis by Interacting with and Activating STAT3

Authors: Yanhong Wang, Na Li, Yanping Zheng, Anqing Wang, Chunlei Yu, Zhenbo Song, Shuyue Wang, Ying Sun, Lihua Zheng, Guannan Wang, Lei Liu, Jingwen Yi, Yanxin Huang, Muqing Zhang, Yongli Bao, Luguo Sun

Journal: Int J Mol Sci

PubMed ID: 35008530

Doi: 10.3390/ijms23010104

Products & Services: Plasmid DNA Preparation

Exposure to in Asian Elephants () in Thailand

Authors: Ruenruetai Udonsom, Yoshifumi Nishikawa, Ragab M Fereig, Thitirat Topisit, Natchakorn Kulkaweewut, Supitcha Chanamrung, Charoonluk Jirapattharasate

Journal: Pathogens

PubMed ID: 35055950

Doi: 10.3390/pathogens11010002

Products & Services: Proteins, Expression, Isolation and Analysis

Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men

Authors: Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong

Journal: Emerg Microbes Infect

PubMed ID: 34709140

Doi: 10.1080/22221751.2021.1999777

Protection against avian coronavirus conferred by oral vaccination with live bacteria secreting LTB-fused viral proteins

Authors: Avishai Lublin, Chen Katz, Nady Gruzdev, Itamar Yadid, Itai Bloch, Yigal Farnoushi, Luba Simanov, Asaf Berkowitz, Dalia Elyahu, Jacob Pitcovski, Ehud Shahar

Journal: Vaccine

PubMed ID: 34998606

Doi: 10.1016/j.vaccine.2021.12.053

Products & Services: GenParts™ DNA Fragments

Microbial synthesis of 4-hydroxybenzoic acid from renewable feedstocks

Authors: Yueyang Chen, Yufen Chen, Lijun Liu, Yang Zhang, Jifeng Yuan

Journal: Food Chem (Oxf)

PubMed ID: 35415641

Doi: 10.1016/j.fochms.2021.100059

Products & Services: Gene Synthesis

Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner

Authors: Khushwant S Bhullar, Fatemeh Ashkar, Jianping Wu

Journal: Food Chem (Oxf)

PubMed ID: 35415678

Doi: 10.1016/j.fochms.2021.100069

Products & Services: Peptide Synthesis

Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors

Authors: Tamara Muliaditan, Leena Halim, Lynsey M Whilding, Benjamin Draper, Daniela Y Achkova, Fahima Kausar, Maya Glover, Natasha Bechman, Appitha Arulappu, Jenifer Sanchez, Katie R Flaherty, Jana Obajdin, Kristiana Grigoriadis, Pierre Antoine, Daniel Larcombe-Young, Caroline M Hull, Richard Buus, Peter Gordon, Anita Grigoriadis, David M Davies, Anna Schurich, John Maher

Journal: Cell Rep Med

PubMed ID: 35028604

Doi: 10.1016/j.xcrm.2021.100457

Products & Services: Gene Synthesis

Engineering a Pseudo-26-kDa Glutathione Transferase from / for Structure, Kinetics, and Ligandin Studies

Authors: Neo Padi, Blessing Oluebube Akumadu, Olga Faerch, Chinyere Aloke, Vanessa Meyer, Ikechukwu Achilonu

Journal: Biomolecules

PubMed ID: 34944488

Doi: 10.3390/biom11121844

Products & Services: PCR Cloning and Subcloning

SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice NF-ĸB Activation

Authors: Jie Xia, Wenqi Tang, Jiangmei Wang, Dengming Lai, Qi Xu, Ruoqiong Huang, Yaoqin Hu, Xiaojue Gong, Jiajie Fan, Qiang Shu, Jianguo Xu

Journal: Front Immunol

PubMed ID: 34950152

Doi: 10.3389/fimmu.2021.791753

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 seroprevalence, seroconversion and neutralizing antibodies in a systemic lupus erythematosus cohort and comparison to controls

Authors: Hannah R Mathew, May Y Choi, Katherine Buhler, Xenia Gukova, Francesca S Cardwell, Heather Waldhauser, Ann E Clarke, Marvin J Fritzler

Journal: Lupus

PubMed ID: 34874781

Doi: 10.1177/09612033211063793

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Soybean miR159 Regulatory Network Involved in Gibberellin-Modulated Resistance to

Authors: Piao Lei, Nawei Qi, Yuan Zhou, Yuanyuan Wang, Xiaofeng Zhu, Yuanhu Xuan, Xiaoyu Liu, Haiyan Fan, Lijie Chen, Yuxi Duan

Journal: Int J Mol Sci

PubMed ID: 34884977

Doi: 10.3390/ijms222313172

Products & Services: Proteins, Expression, Isolation and Analysis

Expression profile of RNA binding protein in cervical cancer using bioinformatics approach

Authors: Zhiyuan Huang, Fang Li, Qinchuan Li

Journal: Cancer Cell Int

PubMed ID: 34863153

Doi: 10.1186/s12935-021-02319-7

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Non-β-blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

Authors: Caroline T Seebauer, Matthew S Graus, Lan Huang, Alex J McCann, Jill Wylie-Sears, Frank R Fontaine, Tara Karnezis, David Zurakowski, Steven J Staffa, Frédéric A Meunier, John B Mulliken, Joyce Bischoff, Mathias Francois

Journal: J Clin Invest

PubMed ID: 34874911

Doi: 10.1172/JCI151109

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RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation

Authors: Fabian Poetz, Joshua Corbo, Yevgen Levdansky, Alexander Spiegelhalter, Doris Lindner, Vera Magg, Svetlana Lebedeva, Jörg Schweiggert, Johanna Schott, Eugene Valkov, Georg Stoecklin

Journal: Nat Commun

PubMed ID: 34887419

Doi: 10.1038/s41467-021-27471-6

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HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma

Authors: Benjy Jy Tan, Kenji Sugata, Omnia Reda, Misaki Matsuo, Kyosuke Uchiyama, Paola Miyazato, Vincent Hahaut, Makoto Yamagishi, Kaoru Uchimaru, Yutaka Suzuki, Takamasa Ueno, Hitoshi Suzushima, Hiroo Katsuya, Masahito Tokunaga, Yoshikazu Uchiyama, Hideaki Nakamura, Eisaburo Sueoka, Atae Utsunomiya, Masahiro Ono, Yorifumi Satou

Journal: J Clin Invest

PubMed ID: 34907908

Doi: 10.1172/JCI150472

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Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

Authors: Yukiko Sato, Kamila R Mustafina, Yishan Luo, Carolina Martini, David Y Thomas, Paul W Wiseman, John W Hanrahan

Journal: Sci Rep

PubMed ID: 34853321

Doi: 10.1038/s41598-021-02420-x

Products & Services: Plasmid DNA Preparation

GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1

Authors: Lucia Balazova, Miroslav Balaz, Carla Horvath, Áron Horváth, Caroline Moser, Zuzana Kovanicova, Adhideb Ghosh, Umesh Ghoshdastider, Vissarion Efthymiou, Elke Kiehlmann, Wenfei Sun, Hua Dong, Lianggong Ding, Ez-Zoubir Amri, Pirjo Nuutila, Kirsi A Virtanen, Tarja Niemi, Barbara Ukropcova, Jozef Ukropec, Pawel Pelczar, Thorsten Lamla, Bradford Hamilton, Heike Neubauer, Christian Wolfrum

Journal: Nat Commun

PubMed ID: 34880217

Doi: 10.1038/s41467-021-27442-x

Products & Services: Mammalian Expression

Rice stripe virus activates the bZIP17/28 branch of the unfolded protein response signalling pathway to promote viral infection

Authors: Chenyang Li, Tianze Zhang, Yu Liu, Zongdi Li, Yaqin Wang, Shuai Fu, Yi Xu, Tong Zhou, Jianxiang Wu, Xueping Zhou

Journal: Mol Plant Pathol

PubMed ID: 34897936

Doi: 10.1111/mpp.13171

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