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Highly portable quantitative screening test for prostate-specific antigen at point of care
Authors: Balaji Srinivasan, David M Nanus, David Erickson, Saurabh Mehta
Journal: Curr Res Biotechnol
PubMed ID: 35083431
Doi: 10.1016/j.crbiot.2021.11.003
Products & Services: Bacterial Expression   
Noncanonical ER-Golgi trafficking and autophagy of endogenous procollagen in osteoblasts
Authors: Laura Gorrell, Shakib Omari, Elena Makareeva, Sergey Leikin
Journal: Cell Mol Life Sci
PubMed ID: 34779895
Doi: 10.1007/s00018-021-04017-z
Products & Services: Synthetic sgRNA and crRNA Service   Gene Synthesis   
Association Between Brain Structural Network Efficiency at Term-Equivalent Age and Early Development of Cerebral Palsy in Very Preterm Infants
Authors: Julia E Kline, Weihong Yuan, Karen Harpster, Mekibib Altaye, Nehal A Parikh
Journal: Neuroimage
PubMed ID: 34758381
Doi: 10.1016/j.neuroimage.2021.118688
Products & Services: Recombinant Proteins   
Preparation of Specific Nanobodies and Their Application in the Rapid Detection of Nodularin-R in Water Samples
Authors: Jinyi Yang, Rui Si, Guangpei Wu, Yu Wang, Ruyu Fang, Fei Liu, Feng Wang, Hongtao Lei, Yudong Shen, Qi Zhang, Hong Wang
Journal: Foods
PubMed ID: 34829042
Doi: 10.3390/foods10112758
Products & Services: Recombinant Antibody Expression   
Comparison of SARS-CoV-2 Antibody Responses and Seroconversion in COVID-19 Patients Using Twelve Commercial Immunoassays
Authors: Sojeong Yun, Ji Hyeong Ryu, Joo Hee Jang, Hyunjoo Bae, Seung-Hyo Yoo, Ae-Ran Choi, Sung Jin Jo, Jihyang Lim, Jehoon Lee, Hyejin Ryu, Sung-Yeon Cho, Dong-Gun Lee, Jongmin Lee, Seok Chan Kim, Yeon-Joon Park, Hyeyoung Lee, Eun-Jee Oh
Journal: Ann Lab Med
PubMed ID: 34108285
Doi: 10.3343/alm.2021.41.6.577
Quantitative assessment of AD markers using naked eyes: point-of-care testing with paper-based lateral flow immunoassay
Authors: Liding Zhang, Xuewei Du, Ying Su, Shiqi Niu, Yanqing Li, Xiaohan Liang, Haiming Luo
Journal: J Nanobiotechnology
PubMed ID: 34789291
Doi: 10.1186/s12951-021-01111-z
Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling
Authors: Dahong Chen, Catherine E McManus, Behram Radmanesh, Leah H Matzat, Elissa P Lei
Journal: Nat Commun
PubMed ID: 34737269
Doi: 10.1038/s41467-021-26628-7
Products & Services: Plasmid DNA Preparation   
Transformation of Reactive Blue 19 by a recombinant peroxidase DyP
Authors: Qian Pi, Zhubing Zhu, Lei Tang
Journal: Bioprocess Biosyst Eng
PubMed ID: 34739595
Doi: 10.1007/s00449-021-02660-1
Products & Services: Plasmid DNA Preparation   
Honokiol improves cognitive impairment in APP/PS1 mice through activating mitophagy and mitochondrial unfolded protein response
Authors: Mingyue Hou, Wenfang Bao, Yuanyuan Gao, Jiayue Chen, Guijun Song
Journal: Chem Biol Interact
PubMed ID: 34752757
Doi: 10.1016/j.cbi.2021.109741
Products & Services: Plasmid DNA Preparation   
Modulating Oncolytic Adenovirus Immunotherapy by Driving Two Axes of the Immune System by Expressing 4-1BBL and CD40L
Authors: Shao-Chia Lu, Michael Hansen, Jack Hemsath, Brian Parrett, Brady Zell, Michael A Barry
Journal: Hum Gene Ther
PubMed ID: 34731019
Doi: 10.1089/hum.2021.197
Products & Services: Peptide Synthesis   
Effective discrimination of gas-phase peptide conformers using TIMS-ECD-ToF MS/MS
Authors: K Jeanne Dit Fouque, M Wellmann, D Leyva Bombuse, M Santos-Fernandez, Y L Cintron-Diaz, M E Gomez-Hernandez, D Kaplan, V G Voinov, F Fernandez-Lima
Journal: Anal Methods
PubMed ID: 34698320
Doi: 10.1039/d1ay01461g
Products & Services: ORF cDNA Clones/MolecularCloud   
Author Correction: Regulation of local GTP availability controls RAC1 activity and cell invasion
Authors: Anna Bianchi-Smiraglia, David W Wolff, Daniel J Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M Wombacher, Ashley L Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O'Brien Cox, Cristina M Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J Sousa, Mikhail E Kandel, Eugene S Kandel, Klaus M Hahn, Mikhail A Nikiforov
Journal: Nat Commun
PubMed ID: 34741006
Doi: 10.1038/s41467-021-26665-2
Products & Services: Mutant Libraries   
Molecular Detection and Characterization of in Farmed Pigs in Three Provinces of Southern China
Authors: Yang Zou, Xiao-Dan Yuan, Sheng-Ying Zhang, Hong-Yan Zhang, Xiao-Qing Chen
Journal: Pathogens
PubMed ID: 34832636
Doi: 10.3390/pathogens10111481
Products & Services: DNA Sequencing   
African Swine Fever Virus pI215L Negatively Regulates cGAS-STING Signaling Pathway through Recruiting RNF138 to Inhibit K63-Linked Ubiquitination of TBK1
Authors: Li Huang, Wenjie Xu, Hongyang Liu, Mengdi Xue, Xiaohong Liu, Kunli Zhang, Liang Hu, Jiangnan Li, Xuemin Liu, Zhida Xiang, Jun Zheng, Changyao Li, Weiye Chen, Zhigao Bu, Tao Xiong, Changjiang Weng
Journal: J Immunol
PubMed ID: 34759016
Doi: 10.4049/jimmunol.2100320
Products & Services: Custom Vector Construction   
Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein
Authors: Mary C Andorfer, Lindsey R F Backman, Phoebe L Li, Emily C Ulrich, Catherine L Drennan
Journal: J Biol Chem
PubMed ID: 34801558
Doi: 10.1016/j.jbc.2021.101423
Products & Services: Codon Optimization   
Engineering Cupriavidus necator DSM 545 for the one-step conversion of starchy waste into polyhydroxyalkanoates
Authors: Silvia Brojanigo, Nicoletta Gronchi, Tiziano Cazzorla, Tuck Seng Wong, Marina Basaglia, Lorenzo Favaro, Sergio Casella
Journal: Bioresour Technol
PubMed ID: 34808314
Doi: 10.1016/j.biortech.2021.126383
Products & Services: Codon Optimization   
Identification and Characterization of Thermostable Y-Family DNA Polymerases η, ι, κ and Rev1 From a Lower Eukaryote, Thermomyces lanuginosus
Authors: Alexandra Vaisman, John P McDonald, Mallory R Smith, Sender L Aspelund, Thomas C Evans, Roger Woodgate
Journal: Front Mol Biosci
PubMed ID: 34805283
Doi: 10.3389/fmolb.2021.778400
Products & Services: Codon Optimization   
Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)-Peptide Tetramers
Authors: Wenqiang Sun, He Zhang, Wenhui Fan, Lihong He, Teng Chen, Xintao Zhou, Yu Qi, Lei Sun, Rongliang Hu, Tingrong Luo, Wenjun Liu, Jing Li
Journal: Viruses
PubMed ID: 34835070
Doi: 10.3390/v13112264
Products & Services: Codon Optimization   
Disulfide Bonds Play a Critical Role in the Structure and Function of the Receptor-binding Domain of the SARS-CoV-2 Spike Antigen
Authors: Andrey M Grishin, Nataliya V Dolgova, Shelby Landreth, Olivier Fisette, Ingrid J Pickering, Graham N George, Darryl Falzarano, Miroslaw Cygler
Journal: J Mol Biol
PubMed ID: 34780781
Doi: 10.1016/j.jmb.2021.167357
Products & Services: Codon Optimization   
Structure of procarboxypeptidase B1 and its binding with Dengue virus for controlling infection
Authors: Edem Gavor, Yeu Khai Choong, Nikhil Kumar Tulsian, Digant Nayak, Fakhriedzwan Idris, Hariharan Sivaraman, Donald Heng Rong Ting, Alonso Sylvie, Yu Keung Mok, R Manjunatha Kini, J Sivaraman
Journal: Life Sci Alliance
PubMed ID: 34750241
Doi: 10.26508/lsa.202101211
Products & Services: Codon Optimization   
Tyrosinase-based production of L-DOPA by Corynebacterium glutamicum
Authors: Eldin Kurpejović, Volker F Wendisch, Berna Sariyar Akbulut
Journal: Appl Microbiol Biotechnol
PubMed ID: 34762142
Doi: 10.1007/s00253-021-11681-5
Products & Services: Codon Optimization   
Overexpression of the rice BAHD acyltransferase AT10 increases xylan-bound p-coumarate and reduces lignin in Sorghum bicolor
Authors: Yang Tian, Chien-Yuan Lin, Joon-Hyun Park, Chuan-Yin Wu, Ramu Kakumanu, Venkataramana R Pidatala, Khanh M Vuu, Alberto Rodriguez, Patrick M Shih, Edward E K Baidoo, Stephen Temple, Blake A Simmons, John M Gladden, Henrik V Scheller, Aymerick Eudes
Journal: Biotechnol Biofuels
PubMed ID: 34801067
Doi: 10.1186/s13068-021-02068-9
Products & Services: Codon Optimization   
A novel DNA platform designed for vaccine use with high transgene expression and immunogenicity
Authors: George Giorgi Babuadze, Jose Echanove, Claude Lamarre, Marc-Antoine deLaVega, Hugues Fausther-Bovendo, Trina Racine, Alejandro M Gomez, Hiva Azizi, Mathew Wade, Robert Kozak, Gary P Kobinger
Journal: Vaccine
PubMed ID: 34774358
Doi: 10.1016/j.vaccine.2021.10.008
Products & Services: Catalog Antibody   
Insulin-activated store-operated Ca entry via Orai1 induces podocyte actin remodeling and causes proteinuria
Authors: Ji-Hee Kim, Kyu-Hee Hwang, Bao T N Dang, Minseob Eom, In Deok Kong, Yousang Gwack, Seyoung Yu, Heon Yung Gee, Lutz Birnbaumer, Kyu-Sang Park, Seung-Kuy Cha
Journal: Nat Commun
PubMed ID: 34764278
Doi: 10.1038/s41467-021-26900-w
Products & Services: Catalog Antibody   
Diagnosis of Streptococcus pneumoniae infection using circulating antibody secreting cells
Authors: Shuya Kyu, Richard P Ramonell, Merin Kuruvilla, Colleen S Kraft, Yun F Wang, Ann R Falsey, Edward E Walsh, John L Daiss, Simon Paulos, Gowrisankar Rajam, Hao Wu, Srinivasan Velusamy, F Eun-Hyung Lee
Journal: PLoS ONE
PubMed ID: 34767590
Doi: 10.1371/journal.pone.0259644
Products & Services: Bacterial Expression   
Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases
Authors: Jinhye Ryu, Zhirong Fu, Srinivas Akula, Anna-Karin Olsson, Lars Hellman
Journal: Dev Comp Immunol
PubMed ID: 34826501
Doi: 10.1016/j.dci.2021.104324
Products & Services: Gene Synthesis   
New and efficient purification process for recombinant human insulin produced in Escherichia coli
Authors: Yin Yin Siew, Amrita Rai, Han Bin Pek, Dave Siak-Wei Ow, Wei Zhang
Journal: Appl Microbiol Biotechnol
PubMed ID: 34821966
Doi: 10.1007/s00253-021-11697-x
Products & Services: Bacterial Expression   
Improved the Activity of Phosphite Dehydrogenase and its Application in Plant Biotechnology
Authors: Tongtong Liu, Lili Yuan, Suren Deng, Xiangxian Zhang, Hongmei Cai, Guangda Ding, Fangsen Xu, Lei Shi, Gaobing Wu, Chuang Wang
Journal: Front Bioeng Biotechnol
PubMed ID: 34900961
Doi: 10.3389/fbioe.2021.764188
Products & Services: Gene Synthesis   
Recombinant Bacillus subtilis flagellin Hag is a potent immunostimulant with reduced proinflammatory properties compared to Salmonella enterica serovar Typhimurium FljB
Authors: Mélanie Côté-Cyr, Laurie Gauthier, Ximena Zottig, Steve Bourgault, Denis Archambault
Journal: Vaccine
PubMed ID: 34844822
Doi: 10.1016/j.vaccine.2021.11.049
Products & Services: Gene Synthesis   
Enhancing the resilience of transgenic cotton for insect resistance
Authors: Mohsin Shad, Aneela Yasmeen, Saira Azam, Allah Bakhsh, Ayesha Latif, Naila Shahid, Sahar Sadaqat, Abdul Qayyum Rao, Ahmad Ali Shahid
Journal: Mol Biol Rep
PubMed ID: 34839448
Doi: 10.1007/s11033-021-06972-z
Inhibition of SGLT1 alleviates the glycemic variability-induced cardiac fibrosisvia inhibiting activations of macrophage and cardiac fibroblast
Authors: Weihua Wu, Qian Chai, Ziying Zhang
Journal: MOL CELL BIOL
PubMed ID: 34842443
Doi: 10.1128/MCB.00282-21
Products & Services: Custom DNA/RNA Oligos   
Genetic manipulation of trehalose-6-phosphate synthase results in changes in the soluble sugar profile in transgenic sugarcane stems
Authors: Casey Gabriel, Jean-Jacque Fernhout, Franziska Fichtner, Regina Feil, John E Lunn, Jens Kossmann, James R Lloyd, Christell van der Vyver
Journal: Plant Direct
PubMed ID: 34765864
Doi: 10.1002/pld3.358
Products & Services: Gene Synthesis   
MmpL3, the trehalose monomycolate transporter, is stable in solution in several detergents and can be reconstituted into peptidiscs
Authors: Kien Lam Ung, Husam Alsarraf, Laurent Kremer, Mickaël Blaise
Journal: Protein Expr Purif
PubMed ID: 34767949
Doi: 10.1016/j.pep.2021.106014
Products & Services: Peptide Synthesis   
A SYBR Green-based real-time RT-PCR assay to differentiate the H1N1 influenza virus lineages
Authors: Yulin Cong, Yixue Sun, Xiaoyu Deng, Haiying Yu, Xiaohuan Lian, Yanlong Cong
Journal: J Virol Methods
PubMed ID: 34848281
Doi: 10.1016/j.jviromet.2021.114387
Products & Services: Gene Synthesis   
ELAPOR1 is a secretory granule maturation-promoting factor that is lost during paligenosis
Authors: Charles J Cho, Dongkook Park, Jason C Mills
Journal: Am J Physiol Gastrointest Liver Physiol
PubMed ID: 34816763
Doi: 10.1152/ajpgi.00246.2021
Products & Services: Gene Synthesis   
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway
Authors: Ying Xing, Yang Liu, Zhong Qi, Zhengrong Liu, Xin Wang, Hongyi Zhang
Journal: Cell Mol Biol Lett
PubMed ID: 34837962
Doi: 10.1186/s11658-021-00295-4
Products & Services: Custom DNA/RNA Oligos   
Structure and activation mechanism of the hexameric plasma membrane H+-ATPase
Authors: Peng Zhao, Chaoran Zhao, Dandan Chen, Caihong Yun, Huilin Li, Lin Bai
Journal: Nat Commun.
PubMed ID: 34750373
Doi: 10.1038/s41467-021-26782-y
Efficient DNA interrogation of SpCas9 governed by its electrostatic interaction with DNA beyond the PAM and protospacer
Authors: Qian Zhang, Ziting Chen, Fangzhu Wang, Siqi Zhang, Hongyu Chen, Xueying Gu, Fengcai Wen, Jiachuan Jin, Xia Zhang, Xingxu Huang
Journal: Nucleic Acids Research
Doi: 10.1093/nar/gkab1139
RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association
Authors: Valérie C Cabana, Antoine Y Bouchard, Audrey M Sénécal, Kim Ghilarducci, Saïd Kourrich, Laurent Cappadocia, Marc P Lussier
Journal: Cells
PubMed ID: 34831286
Doi: 10.3390/cells10113063 Free PMC article
Products & Services: Gene Synthesis   
Zn-Induced Interactions Between SARS-CoV-2 orf7a and BST2/Tetherin
Authors: Maria Petrosino, Francesco Stellato, Roberta Chiaraluce, Valerio Consalvi, Giovanni La Penna, Alessandra Pasquo, Olivier Proux, Giancarlo Rossi, Silvia Morante
Journal: ChemistryOpen
PubMed ID: 34791819
Doi: 10.1002/open.202100217
Products & Services: Gene Synthesis   
A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication
Authors: Sai Wang, Kitti Wing Ki Chan, Min Jie Alvin Tan, Charlotte Flory, Dahai Luo, Julian Lescar, Jade K Forwood, Subhash G Vasudevan
Journal: RNA
PubMed ID: 34759006
Doi: 10.1261/rna.078949.121
Products & Services: Mammalian Expression   
H,  N and  C resonance assignments of the Q61H mutant of human KRAS bound to GDP
Authors: Qiwei Huang, Elizabeth Yihui Ng, Qingxin Li, CongBao Kang
Journal: Biomol NMR Assign
PubMed ID: 34787842
Doi: 10.1007/s12104-021-10058-z
Products & Services: Mammalian Expression   
Inducing I and phase 1 repolarization of the cardiac action potential with a Kv43/KChIP21 bicistronic transgene
Authors: Nan Wang, Eef Dries, Ewan D Fowler, Stephen C Harmer, Jules C Hancox, Mark B Cannell
Journal: J Mol Cell Cardiol
PubMed ID: 34823101
Doi: 10.1016/j.yjmcc.2021.11.004
Products & Services: DNA Sequencing   
Mediates Hormonally Regulated Dominance Rank in a Social Bee
Authors: Atul Pandey, Guy Bloch
Journal: Biology (Basel)
PubMed ID: 34827180
Doi: 10.3390/biology10111188
Products & Services: Molecular Biology Tools   
A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells
Authors: Seon-Yeong Lee, Su-Jin Moon, Young-Mee Moon, Hyeon-Beom Seo, Jun-Geol Ryu, A Ram Lee, Chae Rim Lee, Da-Som Kim, Yang-Mi Her, Jeong Won Choi, Seung-Ki Kwok, Sung-Hwan Park, Mi-La Cho
Journal: Cell Mol Immunol
PubMed ID: 34782759
Doi: 10.1038/s41423-021-00798-2
Products & Services: Codon Optimization   
High SARS-CoV-2 Seroprevalence in Rural Peru, 2021: a Cross-Sectional Population-Based Study
Authors: Andres Moreira-Soto, Johanna Maribel Pachamora Diaz, Lilian González-Auza, Xiomara Jeanleny Merino Merino, Alvaro Schwalb, Christian Drosten, Eduardo Gotuzzo, Michael Talledo, Heriberto Arévalo Ramirez, Roxana Peralta Delgado, Spassky Bocanegra Vargas, Jan Felix Drexler
Journal: mSphere
PubMed ID: 34817236
Doi: 10.1128/mSphere.00685-21
Products & Services: Recombinant Proteins   
The multicellular signalling network of ovarian cancer metastases
Authors: Leah Sommerfeld, Florian Finkernagel, Julia M Jansen, Uwe Wagner, Andrea Nist, Thorsten Stiewe, Sabine Müller-Brüsselbach, Anna M Sokol, Johannes Graumann, Silke Reinartz, Rolf Müller
Journal: Clin Transl Med
PubMed ID: 34841720
Doi: 10.1002/ctm2.633
Products & Services: Gene Synthesis   
A Novel Deoxynivalenol-Activated Wheat Gene Encodes an Antifungal Peptide with Deoxynivalenol Affinity and Protects Plants against Pathogens and Mycotoxins
Authors: Gang Liu, Dong-Yun Zuo, Peng Yang, Wei-Jie He, Zheng Yang, Jing-Bo Zhang, Ai-Bo Wu, Shu-Yuan Yi, He-Ping Li, Tao Huang, Yu-Cai Liao
Journal: J Fungi (Basel)
PubMed ID: 34829228
Doi: 10.3390/jof7110941
Products & Services: Recombinant Antibody Expression   
Influence of flagellin polymorphisms, gene regulation, and responsive memory on the motility of species that cause bacterial spot disease of solanaceous plants
Authors: Maria Laura Malvino, Amie Joy Bott, Cory Edwin Green, Tanvi Majumdar, Sarah Refi Hind
Journal: Mol Plant Microbe Interact
PubMed ID: 34732057
Doi: 10.1094/MPMI-08-21-0211-R
Products & Services: Peptide Synthesis   
The barley HvSTP13GR mutant triggers resistance against biotrophic fungi
Authors: Caroline Ines Skoppek, Wilko Punt, Marleen Heinrichs, Frank Ordon, Gwendolin Wehner, Jens Boch, Jana Streubel
Journal: Mol Plant Pathol
PubMed ID: 34816582
Doi: 10.1111/mpp.13161
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