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页码: 177/1026 每页显示数量

The molecular basis of extensively drug-resistant Salmonella Typhi isolates from pediatric septicemia patients

Authors: Chanmi Kim, Iqra Latif, Durga P Neupane, Gi Young Lee, Ryan S Kwon, Alia Batool, Qasim Ahmed, Muhammad Usman Qamar, Jeongmin Song

Journal: PLoS ONE

PubMed ID: 34582469

Doi: 10.1371/journal.pone.0257744

Products & Services: PCR and Cloning

A new carbohydrate-active oligosaccharide dehydratase is involved in the degradation of ulvan

Authors: Marcus Bäumgen, Theresa Dutschei, Daniel Bartosik, Christoph Suster, Lukas Reisky, Nadine Gerlach, Christian Stanetty, Marko D Mihovilovic, Thomas Schweder, Jan-Hendrik Hehemann, Uwe T Bornscheuer

Journal: J Biol Chem

PubMed ID: 34547290

Doi: 10.1016/j.jbc.2021.101210

Products & Services: PCR Cloning and Subcloning

Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons

Authors: Hung-En Hsia, Johanna Tüshaus, Xiao Feng, Laura I Hofmann, Benedikt Wefers, Denise K Marciano, Wolfgang Wurst, Stefan F Lichtenthaler

Journal: FASEB J

PubMed ID: 34390512

Doi: 10.1096/fj.202100475R

Products & Services: Proteins, Expression, Isolation and Analysis

Neutrophil extracellular traps enhance macrophage killing of bacterial pathogens

Authors: Andrew J Monteith, Jeanette M Miller, C Noel Maxwell, Walter J Chazin, Eric P Skaar

Journal: Sci Adv

PubMed ID: 34516771

Doi: 10.1126/sciadv.abj2101

Products & Services: Endotoxin Detection & Removal System

Design and Selection of Engineered Lytic Proteins With Decolonizing Activity

Authors: Diana Gutiérrez, Lorena Rodríguez-Rubio, Patricia Ruas-Madiedo, Lucía Fernández, Ana Belén Campelo, Yves Briers, Martin Weiss Nielsen, Karl Pedersen, Rob Lavigne, Pilar García, Ana Rodríguez

Journal: Front Microbiol

PubMed ID: 34594314

Doi: 10.3389/fmicb.2021.723834

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A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing

Authors: Bokyung Son, Jennifer Patterson-West, Melissa Arroyo-Mendoza, Revathy Ramachandran, James R Iben, Jingen Zhu, Venigalla Rao, Emilios K Dimitriadis, Deborah M Hinton

Journal: Nucleic Acids Res

PubMed ID: 34365505

Doi: 10.1093/nar/gkab678

Products & Services: Gene Synthesis

miR‑32‑5p suppresses the proliferation and migration of pancreatic adenocarcinoma cells by targeting TLDC1

Authors: Peng Yuan, Chaofeng Tang, Bendong Chen, Peng Lei, Jianjun Song, Guojun Xin, Zuozheng Wang, Yongfeng Hui, Weijie Yao, Genwang Wang, Guozhong Zhao

Journal: Mol Med Rep

PubMed ID: 34468015

Doi: 10.3892/mmr.2021.12392

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Long noncoding RNA LAMTOR5-AS1 interference affects microRNA-506-3p/E2F6-mediated behavior of non-small cell lung cancer cells

Authors: Guojie Chen, Kai Wang, Guoshu Li, Leidong Wang, Yangyang Xiao, Bo Chen

Journal: Oncol Res

PubMed ID: 34588094

Doi: 10.3727/096504021X16328213967104

Products & Services: Gene Synthesis

Myeloma patients with COVID-19 have superior antibody responses compared to patients fully vaccinated with the BNT162b2 vaccine

Authors: Maria Gavriatopoulou, Evangelos Terpos, Panagiotis Malandrakis, Ioannis Ntanasis-Stathopoulos, Alexandros Briasoulis, Sentiljana Gumeni, Despina Fotiou, Eleni-Dimitra Papanagnou, Magdalini Migkou, Foteini Theodorakakou, Evangelos Eleutherakis-Papaiakovou, Nikolaos Kanellias, Ioannis P Trougakos, Efstathios Kastritis, Meletios-Athanasios Dimopoulos

Journal: Br J Haematol

PubMed ID: 34528249

Doi: 10.1111/bjh.17841

Products & Services: PCR and Cloning

A human antibody against human endothelin receptor type A that exhibits antitumor potency

Authors: Man-Seok Ju, Hye-Mi Ahn, Seong-Gu Han, Sanghwan Ko, Jung-Hyun Na, Migyeong Jo, Chung Su Lim, Byoung Joon Ko, Yeon Gyu Yu, Won-Kyu Lee, Youn-Jae Kim, Sang Taek Jung

Journal: Exp Mol Med

PubMed ID: 34588605

Doi: 10.1038/s12276-021-00678-9

Products & Services: Proteins, Expression, Isolation and Analysis

Genome editing with type II-C CRISPR-Cas9 systems from Neisseria meningitidis in rice

Authors: Rongfang Xu, Ruiying Qin, Hongjun Xie, Juan Li, Xiaoshuang Liu, Mingdong Zhu, Yang Sun, Yinghong Yu, Pingli Lu, Pengcheng Wei

Journal: Plant Biotechnol J

PubMed ID: 34582079

Doi: 10.1111/pbi.13716

Products & Services: Synthetic sgRNA and crRNA Service

Neutralizing Antibodies against SARS-CoV-2, Anti-Ad5 Antibodies, and Reactogenicity in Response to Ad5-nCoV (CanSino Biologics) Vaccine in Individuals with and without Prior SARS-CoV-2

Authors: Jorge Hernández-Bello, José Javier Morales-Núñez, Andrea Carolina Machado-Sulbarán, Saúl Alberto Díaz-Pérez, Paola Carolina Torres-Hernández, Paulina Balcázar-Félix, Jesús Alberto Gutiérrez-Brito, José Alvaro Lomelí-Nieto, José Francisco Muñoz-Valle

Journal: Vaccines (Basel)

PubMed ID: 34579284

Doi: 10.3390/vaccines9091047

Modulation of heterologous protein secretion in the thermotolerant methylotrophic yeast Ogataea thermomethanolica TBRC 656 by CRISPR-Cas9 system

Authors: Worarat Kruasuwan, Aekkachai Puseenam, Chitwadee Phithakrotchanakoon, Sutipa Tanapongpipat, Niran Roongsawang

Journal: PLoS ONE

PubMed ID: 34582499

Doi: 10.1371/journal.pone.0258005

Products & Services: Gene Synthesis

An analysis of antibody responses and clinical sequalae of the Sinopharm HB02 COVID19 vaccine in dialysis patients in the United Arab Emirates

Authors: Stephen Geoffrey Holt, Sally Mahmoud, Wasim Ahmed, Juan Manuel Acuna, Ayman Kamal Al Madani, Islam Eltantawy, Walid Abbas Zaher, Gareth John Goodier, Nawal Ahmed Al Kaabi, Ali Abdulkareem Al Obaidli

Journal: Nephrology (Carlton)

PubMed ID: 34569677

Doi: 10.1111/nep.13980

The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation

Authors: Izzy Owen, Debra Yee, Hala Wyne, Theodora Myrto Perdikari, Victoria Johnson, Jeremy Smyth, Robert Kortum, Nicolas L Fawzi, Frank Shewmaker

Journal: J Cell Sci

PubMed ID: 34357401

Doi: 10.1242/jcs.258578

Products & Services: Proteins, Expression, Isolation and Analysis

ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier

Authors: Xihua Yue , Yi Qian , Lianhui Zhu , Bopil Gim, Mengjing Bao , Jie Jia , Shuaiyang Jing , Yijing Wang , Chuanting Tan , Francesca Bottanelli , Pascal Ziltener , Sunkyu Choi , Piliang Hao , Intaek Lee

Journal: BMC Biol

PubMed ID: 34493279

Doi: 10.1186/s12915-021-01137-7

Products & Services: Proteins, Expression, Isolation and Analysis

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation

Authors: Hongyi Zhou, Huabo Su, Weiqin Chen

Journal: Int J Mol Sci

PubMed ID: 34502418

Doi: 10.3390/ijms22179509

Products & Services: CRISPR Plasmids

A Cross-Reactive Monoclonal Antibody Against Neuraminidases of Both H9N2 and H3N2 Influenza Viruses Shows Protection in Mice Challenging Models

Authors: Fei Wang, Zhimin Wan, Jinsen Wu, Yajuan Wang, Hui Fu, Hongxia Shao, Kun Qian, Wei Gao, Jianqiang, Aijian Qin

Journal: Frontiers in Microbiology

Doi: 10.3389/fmicb.2021.730449

Products & Services: Gene Synthesis

Application of the amplification-free SERS-based CRISPR/Cas12a platform in the identification of SARS-CoV-2 from clinical samples

Authors: Jiajie Liang, Peijun Teng, Wei Xiao, Guanbo He, Qifang Song, Ying Zhang, Bin Peng, Gan Li, Liangshan Hu, Donglin Cao, Yong Tang

Journal: J Nanobiotechnology

PubMed ID: 34496881

Doi: 10.1186/s12951-021-01021-0

Products & Services: DNA Sequencing

A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease

Authors: Stephanie Patchett, Zongyang Lv, Wioletta Rut, Miklos Békés, Marcin Drag, Shaun K Olsen, Tony T Huang

Journal: Cell Rep

PubMed ID: 34547223

Doi: 10.1016/j.celrep.2021.109754

Products & Services: DNA Sequencing

Fusion of cellobiose phosphorylase and potato alpha-glucan phosphorylase facilitates substrate channeling for enzymatic conversion of cellobiose to starch

Authors: Xinyu Liu, Huawei Hou, Yapeng Li, Sen Yang, Hui Lin, Hongge Chen

Journal: Prep Biochem Biotechnol

PubMed ID: 34550864

Doi: 10.1080/10826068.2021.1977949

Products & Services: DNA Sequencing

Structure and function relationship of OqxB efflux pump from Klebsiella pneumoniae

Authors: Nagakumar Bharatham, Purnendu Bhowmik, Maho Aoki, Ui Okada, Sreevalli Sharma, Eiki Yamashita, Anirudh P Shanbhag, Sreenath Rajagopal, Teby Thomas, Maitrayee Sarma, Riya Narjari, Savitha Nagaraj, Vasanthi Ramachandran, Nainesh Katagihallimath, Santanu Datta, Satoshi Murakami

Journal: Nat Commun

PubMed ID: 34518546

Doi: 10.1038/s41467-021-25679-0

Products & Services: DNA Sequencing

Association of a GATA Binding Protein 4 Polymorphism with the Risk of Hypospadias in the Chinese Children

Authors: Jiawei Chen, Xinhai Cui, Aiwu Li, Guowei Li, Fengyin Sun

Journal: Urol Int

PubMed ID: 34569527

Doi: 10.1159/000518644

Products & Services: Custom Vector Construction

NMPylation and de-NMPylation of SARS-CoV-2 nsp9 by the NiRAN domain

Authors: Bing Wang, Dmitri Svetlov, Irina Artsimovitch

Journal: Nucleic Acids Res

PubMed ID: 34352100

Doi: 10.1093/nar/gkab677

Products & Services: Custom Vector Construction

A genome-wide screen reveals the involvement of enterobactin-mediated iron acquisition in Escherichia coli survival during copper stress

Authors: Kaitlin Casanova-Hampton, Alexis Carey, Sarah Kassam, Alyssa Garner, George L Donati, Shankar Thangamani, Sargurunathan Subashchandrabose

Journal: Metallomics

PubMed ID: 34415046

Doi: 10.1093/mtomcs/mfab052

Products & Services: Custom Vector Construction

De novo design of tyrosine and serine kinase-driven protein switches

Authors: Nicholas B Woodall, Zara Weinberg, Jesslyn Park, Florian Busch, Richard S Johnson, Mikayla J Feldbauer, Michael Murphy, Maggie Ahlrichs, Issa Yousif, Michael J MacCoss, Vicki H Wysocki, Hana El-Samad, David Baker

Journal: Nat Struct Mol Biol

PubMed ID: 34518698

Doi: 10.1038/s41594-021-00649-8

Products & Services: Custom Vector Construction

The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity

Authors: Konrad J Mostert, Nandini Sharma, Marianne van der Zwaag, Roxine Staats, Lizbé Koekemoer, Ruchi Anand, Ody C M Sibon, Erick Strauss

Journal: ACS Chem Biol

PubMed ID: 34582681

Doi: 10.1021/acschembio.1c00535

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Feline thymidine kinase 1: molecular characterization and evaluation of its serum form as a diagnostic biomarker

Authors: Liya Wang, Hanan Sharif, Sara Saellström, Henrik Rönnberg, Staffan Eriksson

Journal: BMC Vet Res

PubMed ID: 34579716

Doi: 10.1186/s12917-021-03030-5

Products & Services: Custom Vector Construction

Molecular basis of human ATM kinase inhibition

Authors: K Stakyte, M Rotheneder, K Lammens, J D Bartho, U Grädler, T Fuchß, U Pehl, A Alt, E van de Logt, K P Hopfner

Journal: Nat Struct Mol Biol

PubMed ID: 34556870

Doi: 10.1038/s41594-021-00654-x

Products & Services: Custom Vector Construction

Zinc-finger protein MdBBX7/MdCOL9, a target of MdMIEL1 E3 ligase, confers drought tolerance in apple

Authors: Pengxiang Chen, Fang Zhi, Xuewei Li, Wenyun Shen, Mingjia Yan, Jieqiang He, Chana Bao, Tianle Fan, Shuangxi Zhou, Fengwang Ma, Qingmei Guan

Journal: Plant Physiol

PubMed ID: 34618120

Doi: 10.1093/plphys/kiab420

Products & Services: Custom RNAi Services

Spectroscopic evidence of tetanus toxin translocation domain bilayer-induced refolding and insertion

Authors: Pierce T O'Neil, Victor Vasquez-Montes, Liskin Swint-Kruse, Michael R Baldwin, Alexey S Ladokhin

Journal: Biophys J

PubMed ID: 34555358

Doi: 10.1016/j.bpj.2021.09.030

Products & Services: Codon Optimization

Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice

Authors: Xiaoling Cao, Yan Tian, Vi Nguyen, Yuping Zhang, Chao Gao, Rong Yin, Wayne Carver, Daping Fan, Helmut Albrecht, Taixing Cui, Wenbin Tan

Journal: FASEB J

PubMed ID: 34365657

Doi: 10.1096/fj.202002742RR

Products & Services: Codon Optimization

Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing

Authors: Sarah A Schoonraad, Kristine M Fischenich, Kevin N Eckstein, Victor Crespo-Cuevas, Lea M Savard, Archish Muralidharan, Andrew A Tomaschke, Asais Camila Uzcategui, Mark A Randolph, Robert R McLeod, Virginia L Ferguson, Stephanie J Bryant

Journal: Biofabrication

PubMed ID: 34479218

Doi: 10.1088/1758-5090/ac23ab

Products & Services: Catalog Peptides

Serological Assays for Assessing Postvaccination SARS-CoV-2 Antibody Response

Authors: Sally A Mahmoud, Subhashini Ganesan, Shivaraj Naik, Safaa Bissar, Isra Al Zamel, K N Warren, Walid A Zaher, Gulfaraz Khan

Journal: Microbiol Spectr

PubMed ID: 34585943

Doi: 10.1128/Spectrum.00733-21

Products & Services: Serology SARS-Cov-2 detection kits

Isotype-Specific Fc Effector Functions Enhance Antibody-Mediated Rift Valley Fever Virus Protection

Authors: Haley N Cartwright, Dominique J Barbeau, Anita K McElroy

Journal: mSphere

PubMed ID: 34494884

Doi: 10.1128/mSphere.00556-21

Products & Services: Catalog Antibody

Lysine Residues in the MK-Rich Region Are Not Required for Binding of the PbsP Protein From Group B Streptococci to Plasminogen

Authors: Francesco Coppolino, Letizia Romeo, Giampiero Pietrocola, Germana Lentini, Giuseppe Valerio De Gaetano, Giuseppe Teti, Roberta Galbo, Concetta Beninati

Journal: Front Cell Infect Microbiol

PubMed ID: 34568085

Doi: 10.3389/fcimb.2021.679792

Products & Services: Peptide Synthesis

Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs

Authors: Lifeng Fu, Shuai Shao, Yong Feng, Fei Ye, Xue Sun, Qingling Wang, Feng Yu, Qisheng Wang, Baoying Huang, Peihua Niu, Xuebing Li, Catherine C L Wong, Jianxun Qi, Wenjie Tan, George Fu Gao

Journal: MBio

PubMed ID: 34579576

Doi: 10.1128/mBio.02220-21

Products & Services: Peptide Synthesis

Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy

Authors: Taisuke Nakahama, Yuki Kato, Toshiharu Shibuya, Maal Inoue, Jung In Kim, Tuangtong Vongpipatana, Hiroyuki Todo, Yanfang Xing, Yukio Kawahara

Journal: Immunity

PubMed ID: 34525338

Doi: 10.1016/j.immuni.2021.08.022

Products & Services: Stable Cell Lines

Development of a Recombinant RBD Subunit Vaccine for SARS-CoV-2

Authors: Yi-Sheng Sun, Jing-Jing Zhou, Han-Ping Zhu, Fang Xu, Wen-Bin Zhao, Hang-Jing Lu, Zhen Wang, Shu-Qing Chen, Ping-Ping Yao, Jian-Min Jiang, Zhan Zhou

Journal: Viruses

PubMed ID: 34696367

Doi: 10.3390/v13101936

Products & Services: SARS-CoV-2 qRT-PCR Detection Assay

Vaspin Mediates the Intraorgan Crosstalk Between Heart and Adipose Tissue in Lipoatrophic Mice

Authors: Donghui Zhang, Hong Zhu, Enbo Zhan, Fan Wang, Yue Liu, Wei Xu, Xian Liu, Jingjin Liu, Shufeng Li, Yong Pan, Yongshun Wang, Wei Cao

Journal: Front Cell Dev Biol

PubMed ID: 34631690

Doi: 10.3389/fcell.2021.647131

Products & Services: Recombinant Antibody Expression

Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain

Authors: Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Svetlana A Semenova, Avinash Chekuru, Paul Wirsching, Volker Kroehne, Saygın Bilican, Shady Sayed, Sylke Winkler, Sandra Spieß, Anja Machate, Jan Kaslin, Pertti Panula, Michael Brand

Journal: PLoS Genet

PubMed ID: 34516550

Doi: 10.1371/journal.pgen.1009794

Products & Services: Proteins, Expression, Isolation and Analysis

The evidence for and consequences of metabotropic glutamate receptor heterodimerization

Authors: Tyler W McCullock, Paul J Kammermeier

Journal: Neuropharmacology

PubMed ID: 34547332

Doi: 10.1016/j.neuropharm.2021.108801

Products & Services: Proteins, Expression, Isolation and Analysis

Tagging and Capturing of Lentiviral Vectors Using Short RNAs

Authors: Martin Panigaj, Michael P Marino, Jakob Reiser

Journal: Int J Mol Sci

PubMed ID: 34638603

Doi: 10.3390/ijms221910263

Products & Services: Plasmid DNA Preparation

RBD-homodimer, a COVID-19 subunit vaccine candidate, elicits immunogenicity and protection in rodents and nonhuman primates

Authors: Xiaoyan Pan, Jian Shi, Xue Hu, Yan Wu, Liang Zeng, Yanfeng Yao, Weijuan Shang, Kunpeng Liu, Ge Gao, Weiwei Guo, Yun Peng, Shaohong Chen, Xiaoxiao Gao, Cheng Peng, Juhong Rao, Jiaxuan Zhao, Cheng Gong, Hui Zhou, Yudong Lu, Zili Wang, Xiliang Hu, WenJuan Cong, Lijuan Fang, Yongxiang Yan, Jing Zhang, Hui Xiong, Jizu Yi, Zhiming Yuan, Pengfei Zhou, Chao Shan, Gengfu Xiao

Journal: Cell Discov

PubMed ID: 34493710

Doi: 10.1038/s41421-021-00320-y

Products & Services: Plasmid DNA Preparation

Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo

Authors: Debashis Dutta, Malabendu Jana, Moumita Majumder, Susanta Mondal, Avik Roy, Kalipada Pahan

Journal: Nat Commun

PubMed ID: 34508096

Doi: 10.1038/s41467-021-25767-1

Products & Services: Peptide Synthesis

Mass balance method for SI-traceable purity assignment of synthetic oxytocin

Authors: Sheng Wang, Peize Wu, Ming Li, Ting Huang, Naijie Shi, Liuxing Feng, Hongmei Li

Journal: J Pharm Biomed Anal

PubMed ID: 34656934

Doi: 10.1016/j.jpba.2021.114401

Products & Services: Peptide Synthesis

Surface-enhanced Raman scattering-based detection of plasmin activity by specific peptide substrate

Authors: Nazife Nur Yazgan, Tugba Bulat, Ali Topcu, Fahriye Ceyda Dudak, Ismail Hakki Boyaci, Uğur Tamer

Journal: Food Chem

PubMed ID: 34624781

Doi: 10.1016/j.foodchem.2021.131235

Products & Services: Peptide Synthesis

Identification and Characterization of Rift Valley Fever Virus-Specific T Cells Reveals a Dependence on CD40/CD40L Interactions for Prevention of Encephalitis

Authors: Dominique J Barbeau, Haley N Cartwright, Jessica R Harmon, Jessica R Spengler, Christina F Spiropoulou, John Sidney, Alessandro Sette, Anita K McElroy

Journal: J Virol

PubMed ID: 34495703

Doi: 10.1128/JVI.01506-21

Products & Services: Peptide Synthesis

Optimised Heterologous Expression and Functional Analysis of the F1-Capsular Antigen Regulator Caf1R

Authors: Dharmender K Gahlot, Gyles Ifill, Sheila MacIntyre

Journal: Int J Mol Sci

PubMed ID: 34575967

Doi: 10.3390/ijms22189805

Products & Services: ORF cDNA Clones/MolecularCloud

Glucagon-Like Peptide-2 Modulates Enteric Paneth Cells Immune Response and Alleviates Gut Inflammation During Intravenous Fluid Infusion in Mice With a Central Catheter

Authors: Guifang Deng, Qiucheng Lei, Xuejin Gao, Yupeng Zhang, Huazhen Zheng, Jingcheng Bi, Xinying Wang

Journal: Front Nutr

PubMed ID: 34540875

Doi: 10.3389/fnut.2021.688715

Products & Services: Nucleic Acid Purification & Analysis

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