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Long-chain polyphosphates impair SARS-CoV-2 infection and replication

Authors: Veronica Ferrucci, Dae-Young Kong, Fatemeh Asadzadeh, Laura Marrone, Angelo Boccia, Roberto Siciliano, Giuseppina Criscuolo, Camilla Anastasio, Fabrizio Quarantelli, Marika Comegna, Ida Pisano, Margherita Passariello, Ilaria Iacobucci, Rosa Della Monica, Barbara Izzo, Pellegrino Cerino, Giovanna Fusco, Maurizio Viscardi, Sergio Brandi, Bianca Maria Pierri, Giorgia Borriello, Claudia Tiberio, Luigi Atripaldi, Martina Bianchi, Giovanni Paolella, Ettore Capoluongo, Giuseppe Castaldo, Lorenzo Chiariotti, Maria Monti, Claudia De Lorenzo, Kyong-Seop Yun, Stefano Pascarella, Jae-Ho Cheong, Hong-Yeoul Kim, Massimo Zollo

Journal: Sci Signal

PubMed ID: 34230209

Doi: 10.1126/scisignal.abe5040

Products & Services: Mammalian Expression

Endocytosis of peroxiredoxin 1 links sterile inflammation to immunoparalysis in pediatric patients following cardiopulmonary bypass

Authors: Chia-Hsiung Liu, Zheng-Hua Huang, Shu-Chien Huang, Tzuu-Shuh Jou

Journal: Redox Biol

PubMed ID: 34332210

Doi: 10.1016/j.redox.2021.102086

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Pancreatic Extracellular Matrix/Alginate Hydrogels Provide a Supportive Microenvironment for Insulin-Producing Cells

Authors: Dongzhi Wang, Yi Zhu, Yan Huang, Jiachen Zhu, Biwen Zhu, Yahong Zhao, Yuhua Lu, Zhiwei Wang, Yibing Guo

Journal: ACS Biomater Sci Eng

PubMed ID: 34251797

Doi: 10.1021/acsbiomaterials.1c00269

Products & Services: DNA Sequencing

Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells

Authors: Wei-Ching Chen, Minh D To, Peter M K Westcott, Reyno Delrosario, Il-Jin Kim, Mark Philips, Quan Tran, Saumya R Bollam, Hani Goodarzi, Nora Bayani, Olga Mirzoeva, Allan Balmain

Journal: Nat Commun

PubMed ID: 34257283

Doi: 10.1038/s41467-021-24498-7

Products & Services: DNA Sequencing

Topical cationic hairy particles targeting cell free DNA in dermis enhance treatment of psoriasis

Authors: Yanzi Yan, Huiyi Liang, Xingliang Liu, Lixin Liu, Yongming Chen

Journal: Biomaterials

PubMed ID: 34293700

Doi: 10.1016/j.biomaterials.2021.121027

Products & Services: DNA Sequencing

Homodimerization of a proximal region within the C-terminus of the orphan G-protein coupled receptor GPR179

Authors: Wolfrat Bachert, Lisa Klotz, Heinrich Sticht, Ralf Enz

Journal: Neurochem Int

PubMed ID: 34333057

Doi: 10.1016/j.neuint.2021.105150

Products & Services: DNA Sequencing

Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes

Authors: Emma Nilsson, Magdalena Vavakova, Alexander Perfilyev, Johanna Säll, Per-Anders Jansson, Pernille Poulsen, Jonathan Lou S Esguerra, Lena Eliasson, Allan Vaag, Olga Göransson, Charlotte Ling

Journal: Diabetes

PubMed ID: 34315727

Doi: 10.2337/db20-0324

Products & Services: DNA Sequencing

TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway

Authors: Da-Cen Lin, Si-Yi Zheng, Zhi-Guang Zhang, Jian-Hua Luo, Zhuang-Li Zhu, Li Li, Lu-Shan Chen, Xinjian Lin, James S K Sham, Mo-Jun Lin, Rui-Xiang Zhou

Journal: Cancer Lett

PubMed ID: 34311033

Doi: 10.1016/j.canlet.2021.07.038

Products & Services: DNA Sequencing

PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis

Authors: Zili Liu, Honglin Wang, Shaoqian Wang, Jie Gao, Lei Niu

Journal: Bone Joint Res

PubMed ID: 34254815

Doi: 10.1302/2046-3758.107.BJR-2020-0200.R2

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CRISPR-/Cas12a-Mediated Liposome-Amplified Strategy for the Surface-Enhanced Raman Scattering and Naked-Eye Detection of Nucleic Acid and Application to Food Authenticity Screening

Authors: Jianghua Liu, Jiahui Chen, Di Wu, Mingquan Huang, Jian Chen, Ruiyuan Pan, Yongning Wu, Guoliang Li

Journal: Anal Chem

PubMed ID: 34278781

Doi: 10.1021/acs.analchem.1c01163

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Dual Targeting of Endoplasmic Reticulum by Redox-Deubiquitination Regulation for Cancer Therapy

Authors: Biao Cai, Mengfei Hou, Shijun Zhang, Zhixiang Xin, Jiwei Huang, Jingxing Yang, Yueming Wang, Xingyun Cai, Shaowei Xie, Chunfu Zhang, Yiran Huang

Journal: Int J Nanomedicine

PubMed ID: 34354353

Doi: 10.2147/IJN.S321612

Products & Services: Proteins, Expression, Isolation and Analysis

Overexpressed MPS-1 contributes to endometrioma development through the NF-κB signaling pathway

Authors: Yang Liu, Junyan Ma, Liqi Zhang, Jun Lin, Xiaohua Liu

Journal: Reprod Biol Endocrinol

PubMed ID: 34266426

Doi: 10.1186/s12958-021-00796-z

Products & Services: Proteins, Expression, Isolation and Analysis

Latent tuberculosis co-infection is associated with heightened levels of humoral, cytokine and acute phase responses in seropositive SARS-CoV-2 infection

Authors: Anuradha Rajamanickam, Nathella Pavan Kumar, Chandrasekaran Padmapriyadarsini, Arul Nancy, Nandhini Selvaraj, Kushiyasri Karunanithi, Saravanan Munisankar, Shrinivasa Bm, Rachel Mariam Renji, T C Ambu, Vijayalakshmi Venkataramani, Subash Babu

Journal: J Infect

PubMed ID: 34329676

Doi: 10.1016/j.jinf.2021.07.029

Products & Services: Proteins, Expression, Isolation and Analysis

Structure of a mammalian sperm cation channel complex

Authors: Shiyi Lin, Meng Ke, Yuqi Zhang, Zhen Yan, Jianping Wu

Journal: Nature

PubMed ID: 34225353

Doi: 10.1038/s41586-021-03742-6

Products & Services: Proteins, Expression, Isolation and Analysis

Epitope-Paratope Interaction of a Neutralizing Human Anti-Hepatitis B Virus PreS1 Antibody That Recognizes the Receptor-Binding Motif

Authors: Jisu Hong, Youngjin Choi, Yoonjoo Choi, Jiwoo Lee, Hyo Jeong Hong

Journal: Vaccines (Basel)

PubMed ID: 34358170

Doi: 10.3390/vaccines9070754

Products & Services: Proteins, Expression, Isolation and Analysis

Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency

Authors: Gábor Wittmann, Malcolm J Low, Ronald M Lechan

Journal: Mol Metab

PubMed ID: 34329773

Doi: 10.1016/j.molmet.2021.101312

Products & Services: Plasmid DNA Preparation

Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation

Authors: Jialiang Shao, Tiezhu Shi, Hua Yu, Yufeng Ding, Liping Li, Xiang Wang, Xiongjun Wang

Journal: EMBO J

PubMed ID: 34269483

Doi: 10.15252/embj.2020107480

Products & Services: Peptide Synthesis

Clinical utility of a serum biomarker panel in distinguishing prostate cancer from benign prostate hyperplasia

Authors: Michael A Kiebish, Poornima Tekumalla, Shobha Ravipaty, Albert Dobi, Shiv Srivastava, Wenfang Wu, Saurabh Patil, Tracey Friss, Allison Klotz, Alagarsamy Srinivasan, Jennifer Cullen, Inger L Rosner, Amina Ali, Sandra Laszlo, Michele Petrovic, Neil Fleshner, Jeonifer Garren, Greg Miller, Nischal Mahaveer Chand, Leonardo O Rodrigues, Elder Granger, Mark D Kellogg, Shen Luan, Eleftherios Diamandis, Viatcheslav R Akmaev, Rangaprasad Sarangarajan, Chas Bountra, Stephen J Freedland, David G McLeod, Niven R Narain

Journal: Sci Rep

PubMed ID: 34302010

Doi: 10.1038/s41598-021-94438-4

Products & Services: Peptide Synthesis

Hepta-Histidine Inhibits Tau Aggregation

Authors: Kanoh Kondo, Teikichi Ikura, Hikari Tanaka, Kyota Fujita, Sumire Takayama, Yuki Yoshioka, Kazuhiko Tagawa, Hidenori Homma, Su Liu, Ryosuke Kawasaki, Yong Huang, Nobutoshi Ito, Shin-Ichi Tate, Hitoshi Okazawa

Journal: ACS Chem Neurosci

PubMed ID: 34319089

Doi: 10.1021/acschemneuro.1c00164

Products & Services: Peptide Library Services

The importance of vitellogenin receptors in the oviposition of the pond wolf spider, Pardosa pseudoannulata

Authors: Zhi-Ming Yang, Tian-Yu Lu, Yong Wu, Na Yu, Guang-Ming Xu, Qian-Qian Han, Ze-Wen Liu

Journal: Insect Sci

PubMed ID: 34237799

Doi: 10.1111/1744-7917.12933

Products & Services: PCR and Cloning

High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins

Authors: Josefien W Hommes, Rachel M Kratofil, Sigrid Wahlen, Carla J C de Haas, Reeni B Hildebrand, G Kees Hovingh, Micheal Otto, Miranda van Eck, Menno Hoekstra, Suzanne J A Korporaal, Bas G J Surewaard

Journal: Sci Rep

PubMed ID: 34321507

Doi: 10.1038/s41598-021-94651-1

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An octopamine receptor confers selective toxicity of amitraz on honeybees and mites

Authors: Lei Guo, Xin-Yu Fan, Xiaomu Qiao, Craig Montell, Jia Huang

Journal: Elife

PubMed ID: 34263722

Doi: 10.7554/eLife.68268

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Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays

Authors: Ahmed Ismail, Farah M Shurrab, Hadeel T Al-Jighefee, Duaa W Al-Sadeq, Hamda Qotba, Ibrahim Abdu Al-Shaar, Hadi M Yassine, Laith J Abu-Raddad, Gheyath K Nasrallah

Journal: Front Biosci (Landmark Ed)

PubMed ID: 34340267

Doi: 10.52586/4934

Products & Services: Catalog Antibody

Gadolinium-labeled affibody-XTEN recombinant vector for detection of HER2+ lesions of ovarian cancer lung metastasis using quantitative MRI

Authors: Alireza Nomani, Geng Li, Siavash Yousefi, Shawn Wu, Obeid M Malekshah, Shahryar K Nikkhoi, Mehrdad Pourfathi, Rahim Rizi, Arash Hatefi

Journal: J Control Release

PubMed ID: 34284047

Doi: 10.1016/j.jconrel.2021.07.022

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Assays for studying normal suppressive ERAD-associated retrotranslocation pathways in yeast

Authors: Satarupa Bhaduri, Sonya E Neal

Journal: STAR Protoc

PubMed ID: 34278330

Doi: 10.1016/j.xpro.2021.100640

Products & Services: Gene Synthesis

Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry

Authors: Alessandra Luchini, Samantha Micciulla, Giacomo Corucci, Krishna Chaithanya Batchu, Andreas Santamaria, Valerie Laux, Tamim Darwish, Robert A Russell, Michel Thepaut, Isabelle Bally, Franck Fieschi, Giovanna Fragneto

Journal: Sci Rep

PubMed ID: 34290262

Doi: 10.1038/s41598-021-93996-x

Products & Services: Protein Reagents and Products

AstraZeneca (AZD1222) Covid 19 vaccine-associated adverse drug event: a case report

Authors: Capassoni Marco, Ketabchi Sheyda, Cassisa Angelo, Caramelli Riccardo, Molinu Antonietta Anna, Galluccio Felice, Guiducci Serena

Journal: J Med Virol

PubMed ID: 34214206

Doi: 10.1002/jmv.27175

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miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models

Authors: Ruili Wang, Jie Yao, Fuhua Gong, Songsheng Chen, Ya He, Chunting Hu, Chen Li

Journal: Genes Cells

PubMed ID: 34086379

Doi: 10.1111/gtc.12877

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Development of a Bioluminescent Human Osteosarcoma Model in Humanized NSG Mice: A Pilot Study

Authors: Yunmi Ko, Yeon Ho Jeong, Jin-Hee Seo, Jun Ah Lee

Journal: In Vivo

PubMed ID: 34182491

Doi: 10.21873/invivo.12485

Products & Services: Proteins, Expression, Isolation and Analysis

Effective Antitumor of Orally Intestinal Targeting Penetrating Peptide-Loaded Tyroserleutide/PLGA Nanoparticles in Hepatocellular Carcinoma

Authors: Chenjun Ma, Tiantian Wei, Yingying Hua, Zhongjie Wang, Liefeng Zhang

Journal: Int J Nanomedicine

PubMed ID: 34239301

Doi: 10.2147/IJN.S315713

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P2X7R in Mast Cells is a Potential Target for Salicylic Acid and Aspirin in Treatment of Inflammatory Pain

Authors: Yucui Jiang, Fan Ye, Ying Du, Yingxin Zong, Zongxiang Tang

Journal: J Inflamm Res

PubMed ID: 34239315

Doi: 10.2147/JIR.S313348

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Neutrophil elastase promotes neointimal hyperplasia by targeting toll-like receptor 4 (TLR4)-NF-κB signalling

Authors: Mei Yang, Qishan Chen, Li Mei, Guanmei Wen, Weiwei An, Xinmiao Zhou, Kaiyuan Niu, Chenxin Liu, Meixia Ren, Kun Sun, Qingzhong Xiao, Li Zhang

Journal: Br J Pharmacol

PubMed ID: 34076894

Doi: 10.1111/bph.15583

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SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses

Authors: George W Carnell, Katarzyna A Ciazynska, David A Wells, Xiaoli Xiong, Ernest T Aguinam, Stephen H McLaughlin, Donna Mallery, Soraya Ebrahimi, Lourdes Ceron-Gutierrez, Benedikt Asbach, Sebastian Einhauser, Ralf Wagner, Leo C James, Rainer Doffinger, Jonathan L Heeney, John A G Briggs

Journal: J Virol

PubMed ID: 33963055

Doi: 10.1128/JVI.00203-21

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Overexpression of Douglas-Fir () in Induces Embryonic Programs and Embryo-like Structures in the Mutant but Not in Wild Type Plants

Authors: Mariana A Vetrici, Dmytro P Yevtushenko, Santosh Misra

Journal: Plants (Basel)

PubMed ID: 34451571

Doi: 10.3390/plants10081526

Products & Services: Proteins, Expression, Isolation and Analysis

Host-interactor screens of Phytophthora infestans RXLR proteins reveal vesicle trafficking as a major effector-targeted process

Authors: Benjamin Petre, Mauricio P Contreras, Tolga O Bozkurt, Martin H Schattat, Jan Sklenar, Sebastian Schornack, Ahmed Abd-El-Haliem, Roger Castells-Graells, Rosa Lozano-Durán, Yasin F Dagdas, Frank L H Menke, Alexandra M E Jones, Jack H Vossen, Silke Robatzek, Sophien Kamoun, Joe Win

Journal: Plant Cell

PubMed ID: 33677602

Doi: 10.1093/plcell/koab069

Products & Services: Plasmid DNA Preparation

Single-chain Fragment variable antibody targeting cholecystokinin-B receptor for pain reduction

Authors: K N Westlund, M A Montera, A E Goins, S R A Alles, M Afaghpour-Becklund, R Bartel, R Durvasula, A Kunamneni

Journal: Neurobiol Pain

PubMed ID: 34458647

Doi: 10.1016/j.ynpai.2021.100067

Products & Services: Monoclonal Antibody Services

The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response

Authors: Bo Liu, Jiancheng Huang, Amina Ashraf, Oindrila Rahaman, Jing Lou, Ling Wang, Peiliang Cai, Jinping Wen, Shoaib Anwaar, Xiaoli Liu, Hai Ni, Dipyaman Ganguly, Jijun Zhao, Cliff Y Yang

Journal: Nat Commun

PubMed ID: 34215755

Doi: 10.1038/s41467-021-24352-w

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Genome-wide identification of candidate aquaporins involved in water accumulation of pomegranate outer seed coat

Authors: Jianjian Liu, Gaihua Qin, Chunyan Liu, Xiuli Liu, Jie Zhou, Jiyu Li, Bingxin Lu, Jianrong Zhao

Journal: PeerJ

PubMed ID: 34316414

Doi: 10.7717/peerj.11810

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Screening New Xylanase Biocatalysts from the Mangrove Soil Diversity

Authors: Corinne Ivaldi, Mariane Daou, Laurent Vallon, Alexandra Bisotto, Mireille Haon, Sona Garajova, Emmanuel Bertrand, Craig B Faulds, Giuliano Sciara, Adrien Jacotot, Cyril Marchand, Mylène Hugoni, Harivony Rakotoarivonina, Marie-Noëlle Rosso, Caroline Rémond, Patricia Luis, Eric Record

Journal: Microorganisms

PubMed ID: 34361919

Doi: 10.3390/microorganisms9071484

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Tobacco BY2 cells expressing recombinant cardosin B as an alternative for production of active milk clotting enzymes

Authors: André Folgado, Rita Abranches

Journal: Sci Rep

PubMed ID: 34262119

Doi: 10.1038/s41598-021-93882-6

Products & Services: Mammalian Expression

Heat-dependent opening of TRPV1 in the presence of capsaicin

Authors: Do Hoon Kwon, Feng Zhang, Yang Suo, Jonathan Bouvette, Mario J Borgnia, Seok-Yong Lee

Journal: Nat Struct Mol Biol

PubMed ID: 34239123

Doi: 10.1038/s41594-021-00616-3

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The upstream 5' splice site remains associated to the transcription machinery during intron synthesis

Authors: Yodfat Leader, Galit Lev Maor, Matan Sorek, Ronna Shayevitch, Maram Hussein, Ofir Hameiri, Luna Tammer, Jonathan Zonszain, Ifat Keydar, Dror Hollander, Eran Meshorer, Gil Ast

Journal: Nat Commun

PubMed ID: 34315864

Doi: 10.1038/s41467-021-24774-6

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Low neutralizing antibody responses in WM, CLL and NHL patients after the first dose of the BNT162b2 and AZD1222 vaccine

Authors: Maria Gavriatopoulou, Evangelos Terpos, Efstathios Kastritis, Alexandros Briasoulis, Sentiljana Gumeni, Ioannis Ntanasis-Stathopoulos, Aimilia D Sklirou, Panagiotis Malandrakis, Evangelos Eleutherakis-Papaiakovou, Magdalini Migkou, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Clin Exp Med

PubMed ID: 34283338

Doi: 10.1007/s10238-021-00746-4

Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: implications for the ability of serological assays to predict immunity

Authors: Frauke Muecksch, Helen Wise, Kate Templeton, Becky Batchelor, Maria Squires, Kirsty McCance, Lisa Jarvis, Kristen Malloy, Elizabeth Furrie, Claire Richardson, Jacqueline MacGuire, Ian Godber, Alana Burns, Sally Mavin, Fengwen Zhang, Fabian Schmidt, Paul Bieniasz, Sara Jenks, Theodora Hatziioannou

Journal: medrxiv

PubMed ID: 34268524

Doi: 10.1101/2021.07.02.21259939

Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

Authors: Jérémie Prévost, Jonathan Richard, Romain Gasser, Shilei Ding, Clément Fage, Sai Priya Anand, Damien Adam, Natasha Gupta Vergara, Alexandra Tauzin, Mehdi Benlarbi, Shang Yu Gong, Guillaume Goyette, Anik Privé, Sandrine Moreira, Hugues Charest, Michel Roger, Walther Mothes, Marzena Pazgier, Emmanuelle Brochiero, Guy Boivin, Cameron F Abrams, Arne Schön, Andrés Finzi

Journal: biorxiv

PubMed ID: 34268505

Doi: 10.1101/2021.07.09.451812

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

Authors: Hao Huang, Alexander Gont, Lynn Kee, Ruben Dries, Kathrin Pfeifer, Bandana Sharma, David N Debruyne, Matthew Harlow, Satyaki Sengupta, Jikui Guan, Caleb M Yeung, Wenchao Wang, Bengt Hallberg, Ruth H Palmer, Meredith S Irwin, Rani E George

Journal: Cell Rep

PubMed ID: 34260934

Doi: 10.1016/j.celrep.2021.109363

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LncRNA HOXA11-AS promotes cell growth by sponging miR-24-3p to regulate JPT1 in prostate cancer

Authors: Y Cheng, H-Y Xiong, Y-M Li, H-R Zuo, Y Liu, G-L Liao

Journal: Eur Rev Med Pharmacol Sci

PubMed ID: 34337714

Doi: 10.26355/eurrev_202107_26377

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Association of total and neutralizing SARS-CoV-2 spike -receptor binding domain antibodies with epidemiological and clinical characteristics after immunization with the 1 and 2 doses of the BNT162b2 vaccine

Authors: Athanasios Michos, Elizabeth-Barbara Tatsi, Filippos Filippatos, Charilaos Dellis, Dimitra Koukou, Vasiliki Efthymiou, Evangelia Kastrinelli, Aimilia Mantzou, Vasiliki Syriopoulou

Journal: Vaccine

PubMed ID: 34400017

Doi: 10.1016/j.vaccine.2021.07.067

An increase in VGF expression through a rapid, transcription-independent, autofeedback mechanism improves cognitive function

Authors: Wei-Jye Lin, Yan Zhao, Zhe Li, Shuyu Zheng, Jin-Lin Zou, Noël A Warren, Purva Bali, Jingru Wu, Mengdan Xing, Cheng Jiang, Yamei Tang, Stephen R Salton, Xiaojing Ye

Journal: Transl Psychiatry

PubMed ID: 34238925

Doi: 10.1038/s41398-021-01489-2

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Activation of Adenosine A Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist

Authors: Lingyu Ruan, Guanghui Li, Wenlong Zhao, Huihui Meng, Qi Zheng, Junsong Wang

Journal: Antioxidants (Basel)

PubMed ID: 34356346

Doi: 10.3390/antiox10071112

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