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页码: 188/1026 每页显示数量

Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function

Authors: Benjamin Bourgeois, Tianshu Gui, Diana Hoogeboom, Henry G Hocking, Gesa Richter, Emil Spreitzer, Martin Viertler, Klaus Richter, Tobias Madl, Boudewijn M T Burgering

Journal: Cell Rep

PubMed ID: 34320339

Doi: 10.1016/j.celrep.2021.109446

Products & Services: Gene Synthesis

Protocol for interfering peptide injection into adult mouse hippocampus and spatial memory testing

Authors: Shanshan Cheng, Yuqian Shen, Zi Chao Zhang, Junhai Han

Journal: STAR Protoc

PubMed ID: 34337444

Doi: 10.1016/j.xpro.2021.100679

Products & Services: Peptide Synthesis

A novel larval diet interacts with nutritional stress to modify juvenile behaviors and glucocorticoid responses

Authors: Cristina C Ledón-Rettig, Sarah R Lagon

Journal: Ecol Evol

PubMed ID: 34429887

Doi: 10.1002/ece3.7860

Products & Services: Proteins, Expression, Isolation and Analysis

Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk

Authors: Chathura D Suraweera , Mark G Hinds , Marc Kvansakul

Journal: Viruses

PubMed ID: 34372579

Doi: 10.3390/v13071374

Products & Services: Gene Synthesis

Chromosome-level genome of Himalayan yew provides insights into the origin and evolution of the paclitaxel biosynthetic pathway

Authors: Jian Cheng , Xiao Wang, Xiaonan Liu , Xiaoxi Zhu , Zihe Li , Huanyu Chu , Qian Wang , QianQian Lou , Bijun Cai , Yiqun Yang , Xiaoyun Lu , Kai Peng , Dingyu Liu , Yuwan Liu , Lina Lu , Huan Liu , Ting Yang , Qijin Ge , Chengcheng Shi , Guichun Liu , Zhiwei Dong , Xun Xu , Wen Wang , Huifeng Jiang , Yanhe Ma

Journal: Mol Plant

PubMed ID: 33951484

Doi: 10.1016/j.molp.2021.04.015

Products & Services: Gene Synthesis

Immunomodulatory, trypanocide, and antioxidant properties of essential oil fractions of Lippia alba (Verbenaceae)

Authors: Wendy Lorena Quintero, Erika Marcela Moreno, Sandra Milena Leal Pinto, Sandra Milena Sanabria, Elena Stashenko, Liliana Torcoroma García

Journal: BMC Complement Med Ther

PubMed ID: 34215249

Doi: 10.1186/s12906-021-03347-6

Products & Services: PCR Cloning and Subcloning

Evidence for a chromosome origin unwinding system broadly conserved in bacteria

Authors: Simone Pelliciari, Mei-Jing Dong, Feng Gao, Heath Murray

Journal: Nucleic Acids Res

PubMed ID: 34197592

Doi: 10.1093/nar/gkab560

Products & Services: Gene Synthesis

Structural Modeling of the Treponema pallidum Outer Membrane Protein Repertoire: a Road Map for Deconvolution of Syphilis Pathogenesis and Development of a Syphilis Vaccine

Authors: Kelly L Hawley, Jairo M Montezuma-Rusca, Kristina N Delgado, Navreeta Singh, Vladimir N Uversky, Melissa J Caimano, Justin D Radolf, Amit Luthra

Journal: J Bacteriol

PubMed ID: 33972353

Doi: 10.1128/JB.00082-21

Products & Services: Codon Optimization

Genetic Code Expansion: A Brief History and Perspective

Authors: Mia A Shandell, Zhongping Tan, Virginia W Cornish

Journal: Biochemistry

PubMed ID: 34196546

Doi: 10.1021/acs.biochem.1c00286

Products & Services: Molecular Biology Tools

Signal-transducing adaptor protein-2 has a nonredundant role for IL-33-triggered mast cell activation

Authors: Jun-Ichi Kashiwakura, Nao Koizumi, Kodai Saitoh, Kota Kagohashi, Yuto Sasaki, Fuki Kobayashi, Shoya Kawahara, Yukie Yamauchi, Yuichi Kitai, Ryuta Muromoto, Kenji Oritani, Tadashi Matsuda

Journal: Biochem Biophys Res Commun

PubMed ID: 34358967

Doi: 10.1016/j.bbrc.2021.07.098

Products & Services: Proteins, Expression, Isolation and Analysis

Optimizing the Expression and Solubilization of an E coli-Produced Leukemia Inhibitory Factor for Anti-LIF Antibody Production and Use Thereof for Contraception in Mice

Authors: Nahid Mehri, Abbas Jamshidizad, Zahra Ghanei, Ali-Asghar Karkhane, Mehdi Shamsara

Journal: Mol Biotechnol

PubMed ID: 34272681

Doi: 10.1007/s12033-021-00369-w

Products & Services: Codon Optimization

Characterization of gH/gL/pUL128-131 pentameric complex, gH/gL/gO trimeric complex, gB and gM/gN glycoproteins in a human cytomegalovirus using automated capillary western blots

Authors: Richard R Rustandi, John W Loughney, Liang Shang, Shiyi Wang, Cindy J Pauley, Sianny Christanti, Adam Kristopeit, Timothy D Culp

Journal: Vaccine

PubMed ID: 34229890

Doi: 10.1016/j.vaccine.2021.06.033

Products & Services: Mammalian Expression

Altered chromatin architecture and gene expression during polyploidization and domestication of soybean

Authors: Longfei Wang, Guanghong Jia, Xinyu Jiang, Shuai Cao, Z Jeffrey Chen, Qingxin Song

Journal: Plant Cell

PubMed ID: 33730165

Doi: 10.1093/plcell/koab081

Products & Services: Proteins, Expression, Isolation and Analysis

The Neurotrophin Receptor TrkC as a Novel Molecular Target of the Antineuroblastoma Action of Valproic Acid

Authors: Simona Dedoni, Luisa Marras, Maria C Olianas, Angela Ingianni, Pierluigi Onali

Journal: Int J Mol Sci

PubMed ID: 34360553

Doi: 10.3390/ijms22157790

Products & Services: Mammalian Expression

Cellular 5'-3' mRNA Exoribonuclease XRN1 Inhibits Interferon Beta Activation and Facilitates Influenza A Virus Replication

Authors: Yen-Chin Liu, Bobo Wing-Yee Mok, Pui Wang, Rei-Lin Kuo, Honglin Chen, Shin-Ru Shih

Journal: MBio

PubMed ID: 34311580

Doi: 10.1128/mBio.00945-21

Products & Services: Plasmid DNA Preparation

Functional expression of the eukaryotic proton pump rhodopsin OmR2 in Escherichia coli and its photochemical characterization

Authors: Masuzu Kikuchi, Keiichi Kojima, Shin Nakao, Susumu Yoshizawa, Shiho Kawanishi, Atsushi Shibukawa, Takashi Kikukawa, Yuki Sudo

Journal: Sci Rep

PubMed ID: 34285294

Doi: 10.1038/s41598-021-94181-w

Products & Services: Mammalian Expression

CTP and coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning

Authors: James A Taylor, Yeonee Seol, Jagat Budhathoki, Keir C Neuman, Kiyoshi Mizuuchi

Journal: Elife

PubMed ID: 34286695

Doi: 10.7554/eLife.65651

Products & Services: PCR Cloning and Subcloning

The circadian clock gates adult emergence by controlling the timecourse of metamorphosis

Authors: Brandon Mark, Liliana Bustos-González, Guadalupe Cascallares, Felipe Conejera, John Ewer

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34183412

Doi: 10.1073/pnas.2023249118

Products & Services: Proteins, Expression, Isolation and Analysis

Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes

Authors: Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P M Labib

Journal: Biochem J

PubMed ID: 34195792

Doi: 10.1042/BCJ20210315

Products & Services: Mammalian Expression

KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D

Authors: Yonglan Wang, Kun Cao

Journal: J Immunol Res

PubMed ID: 34307695

Doi: 10.1155/2021/9965099

Structural and immunological characterization of an epitope within the PAN motif of ectodomain I in apical membrane antigen 1 for vaccine development

Authors: Amarin Rittipornlertrak, Boondarika Nambooppha, Anucha Muenthaisong, Veerasak Punyapornwithaya, Saruda Tiwananthagorn, Yang-Tsung Chung, Bumduuren Tuvshintulga, Thillaiampalam Sivakumar, Naoaki Yokoyama, Nattawooti Sthitmatee

Journal: PeerJ

PubMed ID: 34316404

Doi: 10.7717/peerj.11765

Products & Services: Catalog Peptides

Identification of Three Clf-Sdr Subfamily Proteins in , and Comparative Genomics Analysis of a Locus Encoding CWA Proteins in Species

Authors: Zhewei Sun, Xueya Zhang, Danying Zhou, Kexin Zhou, Qiaoling Li, Hailong Lin, Wei Lu, Hongmao Liu, Junwan Lu, Xi Lin, Kewei Li, Teng Xu, Mei Zhu, Qiyu Bao, Hailin Zhang

Journal: Front Microbiol

PubMed ID: 34394031

Doi: 10.3389/fmicb.2021.691087

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The enhanced phosphorus use efficiency in phosphate-deficient and mycorrhiza-inoculated barley seedlings involves activation of different sets of PHT1 transporters in roots

Authors: Rajat Srivastava, Parul Sirohi, Harsh Chauhan, Rahul Kumar

Journal: Planta

PubMed ID: 34312721

Doi: 10.1007/s00425-021-03687-0

Products & Services: Protein Tools

Global Profiling of Phosphorylation Reveals the Barley Roots Response to Phosphorus Starvation and Resupply

Authors: Zengke Ma, Juncheng Wang, Chengdao Li, Panrong Ren, Lirong Yao, Baochun Li, Yaxiong Meng, Xiaole Ma, Erjing Si, Ke Yang, Xunwu Shang, Huajun Wang

Journal: Front Plant Sci

PubMed ID: 34335649

Doi: 10.3389/fpls.2021.676432

Products & Services: Protein Tools

AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment

Authors: Yue Yu, Shu-Ming Ye, De-Yun Liu, Li-Qi Yang

Journal: Exp Anim

PubMed ID: 34305077

Doi: 10.1538/expanim.21-0056

Products & Services: Custom DNA/RNA Oligos

CABE-RY: A PAM-flexible dual-mutation base editor for reliable modeling of multi-nucleotide variants

Authors: Wanyu Tao, Qing Liu, Shisheng Huang, Xin Wang, Shiyuan Qu, Junfan Guo, Danfeng Ou, Guanglei Li, Yu Zhang, Xiangmin Xu, Xingxu Huang

Journal: Mol Ther Nucleic Acids

PubMed ID: 34513298

Doi: 10.1016/j.omtn.2021.07.016

Products & Services: PCR Cloning and Subcloning

Characterization of the Role of the Neoxanthin Synthase Gene in Carotenoid Biosynthesis in Chinese Kale

Authors: Yue Jian, Chenlu Zhang, Yating Wang, Zhiqing Li, Jing Chen, Wenting Zhou, Wenli Huang, Min Jiang, Hao Zheng, Mengyao Li, Huiying Miao, Fen Zhang, Huanxiu Li, Qiaomei Wang, Bo Sun

Journal: Genes (Basel)

PubMed ID: 34440295

Doi: 10.3390/genes12081122

Products & Services: Protein Tools

K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle

Authors: Yuanyuan Yu, Qingyun Zheng, Satchal K Erramilli, Man Pan, Seongjin Park, Yuan Xie, Jingxian Li, Jingyi Fei, Anthony A Kossiakoff, Lei Liu, Minglei Zhao

Journal: Nat Chem Biol

PubMed ID: 34239127

Doi: 10.1038/s41589-021-00823-5

Products & Services: Catalog Antibody

Muscone suppresses gastric cancer via regulation of miRNA-145

Authors: Feng Gao, Shihai Yan, Zheng Sun, Jia Wang

Journal: Food Sci Nutr

PubMed ID: 34531985

Doi: 10.1002/fsn3.2269

Products & Services: Gene Synthesis

The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach

Authors: Sergio Romero-Romero, Miguel Costas, Daniel-Adriano Silva Manzano, Sina Kordes, Erendira Rojas-Ortega, Cinthya Tapia, Yasel Guerra, Sooruban Shanmugaratnam, Adela Rodríguez-Romero, David Baker, Birte Höcker, D Alejandro Fernández-Velasco

Journal: J Mol Biol

PubMed ID: 34271011

Doi: 10.1016/j.jmb.2021.167153

Products & Services: Gene Synthesis

A Cas12a-based CRISPR interference system for multigene regulation in mycobacteria

Authors: Neil Fleck, Christoph Grundner

Journal: J Biol Chem

PubMed ID: 34298016

Doi: 10.1016/j.jbc.2021.100990

Products & Services: Gene Synthesis

Longitudinal evaluation of laboratory-based serological assays for SARS-CoV-2 antibody detection

Authors: K A Bond, E Williams, S Nicholson, S Lim, D Johnson, B Cox, M Putland, E Gardiner, E Tippett, M Graham, F Mordant, M Catton, S R Lewin, K Subbarao, B P Howden, D A Williamson

Journal: Pathology

PubMed ID: 34412859

Doi: 10.1016/j.pathol.2021.05.093

Products & Services: Catalog Antibody

Fast and reliable detection of SARS-CoV-2 antibodies based on surface plasmon resonance

Authors: Caroline Rodrigues Basso, Camila Dantas Malossi, Amanda Haisi, Valber de Albuquerque Pedrosa, Alexandre Naime Barbosa, Rejane Tommasini Grotto, João Pessoa Araujo Junior

Journal: Anal Methods

PubMed ID: 34231576

Doi: 10.1039/d1ay00737h

Products & Services: Recombinant Proteins

Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes

Authors: Lucas F de Lima, André L Ferreira, Marcelo D T Torres, William R de Araujo, Cesar de la Fuente-Nunez

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34244421

Doi: 10.1073/pnas.2106724118

Products & Services: Mammalian Expression

Selective Inhibitors of the Inducible Nitric Oxide Synthase as Modulators of Cell Responses in LPS-Stimulated Human Monocytes

Authors: Marialucia Gallorini, Monica Rapino, Helmut Schweikl, Amelia Cataldi, Rosa Amoroso, Cristina Maccallini

Journal: Molecules

PubMed ID: 34361571

Doi: 10.3390/molecules26154419

Products & Services: Proteins, Expression, Isolation and Analysis

Circular RNA Circ_0067934 Attenuates Ferroptosis of Thyroid Cancer Cells by miR-545-3p/SLC7A11 Signaling

Authors: Hui-Hui Wang, Jia-Ni Ma, Xiao-Rong Zhan

Journal: Front Endocrinol (Lausanne)

PubMed ID: 34290668

Doi: 10.3389/fendo.2021.670031

Products & Services: Gene Synthesis

CRISPR/Cas9-based inactivation of human papillomavirus oncogenes E6 or E7 induces senescence in cervical cancer cells

Authors: Raviteja Inturi, Per Jemth

Journal: Virology

PubMed ID: 34280810

Doi: 10.1016/j.virol.2021.07.005

Products & Services: Codon Optimization

Neutralizing Antibodies Titers and Side Effects in Response to BNT162b2 Vaccine in Healthcare Workers with and without Prior SARS-CoV-2 Infection

Authors: José Javier Morales-Núñez, José Francisco Muñoz-Valle, Carlos Meza-López, Lin-Fa Wang, Andrea Carolina Machado Sulbarán, Paola Carolina Torres-Hernández, Martín Bedolla-Barajas, Brenda De la O-Gómez, Paulina Balcázar-Félix, Jorge Hernández-Bello

Journal: Vaccines (Basel)

PubMed ID: 34358158

Doi: 10.3390/vaccines9070742

Short carboxyl terminal parathyroid hormone peptides modulate human parathyroid hormone signaling in mouse osteoblasts

Authors: Kittrawee Kritmetapak, Ravinder J Singh, Theodore A Craig, Jolaine M Hines, Rajiv Kumar

Journal: Biochem Biophys Res Commun

PubMed ID: 34332324

Doi: 10.1016/j.bbrc.2021.07.085

Products & Services: Plasmid DNA Preparation

Charting elimination in the pandemic: a SARS-CoV-2 serosurvey of blood donors in New Zealand

Authors: Lauren H Carlton, Tiffany Chen, Alana L Whitcombe, Reuben McGregor, Greg Scheurich, Campbell R Sheen, James M Dickson, Chris Bullen, Annie Chiang, Daniel J Exeter, Janine Paynter, Michael G Baker, Richard Charlewood, Nicole J Moreland

Journal: Epidemiol Infect

PubMed ID: 34668464

Doi: 10.1017/S0950268821001643

Products & Services: Recombinant Proteins

An MST4-pβ-Catenin Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis

Authors: Hui Zhang, Moubin Lin, Chao Dong, Yang Tang, Liwei An, Junyi Ju, Fuping Wen, Fan Chen, Meng Wang, Wenjia Wang, Min Chen, Yun Zhao, Jixi Li, Steven X Hou, Xinhua Lin, Lulu Hu, Wenbo Bu, Dianqing Wu, Lin Li, Shi Jiao, Zhaocai Zhou

Journal: Adv Sci (Weinh)

PubMed ID: 34240584

Doi: 10.1002/advs.202004850

Products & Services: CRISPR Libraries

Fine-tuning the expression of pathway gene in yeast using a regulatory library formed by fusing a synthetic minimal promoter with different Kozak variants

Authors: Liping Xu, Pingping Liu, Zhubo Dai, Feiyu Fan, Xueli Zhang

Journal: Microb Cell Fact

PubMed ID: 34320991

Doi: 10.1186/s12934-021-01641-z

Products & Services: Plasmid DNA Preparation

CRISPR/Cas9-mediated engineering of Escherichia coli for n-butanol production from xylose in defined medium

Authors: Ali Samy Abdelaal, Kamran Jawed, Syed Shams Yazdani

Journal: J Ind Microbiol Biotechnol

PubMed ID: 30982114

Doi: 10.1007/s10295-019-02180-8

Products & Services: Gene Synthesis

Assessment of infectivity and the impact on neutralizing activity of immune sera of the COVID-19 variant, CAL.20C

Authors: Zhongcheng Zhou, Peng Du, Meixing Yu, Daniel T. Baptista-Hon, Man Miao, Andy P. Xiang, Johnson Yiu-Nam Lau, COVID-19 Immunity Investigation Group, Gen Li, Kang Zhang

Journal: Signal transduction and targeted therapy

PubMed ID: 34315848

Doi: 10.1038/s41392-021-00695-0

Products & Services: Gene Services

Development of an Immunochromatographic Strip Using Conjugated Gold Nanoparticles for the Rapid Detection of Klebsiella pneumoniae Causing Neonatal Sepsis

Authors: Noha M. Elhosseiny, Tamer M. Samir, Aliaa A. Ali , Amani A. El‐Kholy and Ahmed S. Attia

Journal: Pharmaceutics

PubMed ID: 34452099

Doi: 10.3390/pharmaceutics13081141

Products & Services: Peptide Synthesis

Three optimized assays for the evaluation of compounds that can rescue p53 mutants

Authors: Jiale Wu, Huaxin Song, Zhengyuan Wang, Min Lu

Journal: STAR Protoc

PubMed ID: 34382015

Doi: 10.1016/j.xpro.2021.100688

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Effects of sevoflurane exposure during different stages of pregnancy on the brain development of rat offspring

Authors: Feng-He Cui, Jie Li, Ke-Zhong Li, Yong-Gang Xie, Xiao-Ling Zhao

Journal: J Anesth

PubMed ID: 34279702

Doi: 10.1007/s00540-021-02972-2

Products & Services: Recombinant Proteins

Evaluation of a novel biomarker of type XXVIII collagen formation, PRO-C28, in samples from cancer and heart failure with preserved ejection fraction patients

Authors: Alexander L Reese-Petersen, Nicholas Willumsen, Patricia Palau, Julio Nunez, Shu Sun, Tina Manon Jensen, Bibi Kamall, Morten A Karsdal, Federica Genovese

Journal: J Pharm Biomed Anal

PubMed ID: 34358813

Doi: 10.1016/j.jpba.2021.114272

Products & Services: Peptide Synthesis

Identification of a Novel Cleavage Site and Confirmation of the Effectiveness of NgAgo Gene Editing on RNA Targets

Authors: Jiayao Qu, Yali Xie, Zhaoyi Guo, Xiangting Liu, Jing Jiang, Ting Chen, Kai Li, Zheng Hu, Dixian Luo

Journal: Mol Biotechnol

PubMed ID: 34302285

Doi: 10.1007/s12033-021-00372-1

Products & Services: Nucleic Acid Purification & Analysis

HBx represses WDR77 to enhance HBV replication by DDB1-mediated WDR77 degradation in the liver

Authors: Hongfeng Yuan, Lina Zhao, Ying Yuan, Haolin Yun, Wei Zheng, Yu Geng, Guang Yang, Yufei Wang, Man Zhao, Xiaodong Zhang

Journal: Theranostics

PubMed ID: 34373747

Doi: 10.7150/thno.57531

Products & Services: Nucleic Acid Purification & Analysis

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