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页码: 48/1026 每页显示数量

Nanopore Signatures of Nucleoside Drugs

Authors: Wendong Jia , Yusheng Ouyang , Shanyu Zhang , Xiaoyu Du , Panke Zhang , Shuo Huang

Journal: Nano Lett .

PubMed ID: 37818841

Doi: 10.1021/acs.nanolett.3c02872

Products & Services: Plasmid DNA Preparation

A chlorophyll c synthase widely co-opted by phytoplankton

Authors: Yanyou Jiang , Tianjun Cao , Yuqing Yang , Huan Zhang , Jingyu Zhang , Xiaobo Li

Journal: Science .

PubMed ID: 37797009

Doi: 10.1126/science.adg7921

Products & Services: Gene Synthesis

HDL mimetics protect Alzheimer’s patients carrying APOE ε4 from SARS-CoV-2 invasion

Authors: Ruodan Xu , Junwei Gao , Can Cao , Mingfei Shi , Yonghui Zhang , Shihao Hong , Shijie Guo , Menglin Chen , Ping Song , Gaoshuang Fu , Jing Li , Tengxiao Liang , Yingchun Miao , Lu Tang , Jinsheng Yang , Ning Li , Mingdong Dong

Journal: Nano Today

Doi: 10.1016/j.nantod.2023.102051

Products & Services: Gene Synthesis Peptide Synthesis

Development and characterization of anti-IL-5 monoclonal antibody Fab fragment for blocking IL-5/IL-5Rα binding

Authors: Shijie Li , Shijie Wang , Eric Fordjour , Yaoji Liang , Xuelian Wang , Yonghao Ye , Zhonghu Bai , Yankun Yang , Yongqi Chen

Journal: International Immunopharmacology

Doi: 10.1016/j.intimp.2023.111032

Products & Services: Gene Synthesis Peptide Synthesis

Architecture and rearrangements of a sperm-specific Na/H exchanger

Authors: Sandipan Chowdhury, Kamalendu Pal

Journal: Res Sq

PubMed ID: 37886505

Doi: 10.21203/rs.3.rs-3396005/v1

Products & Services: Proteins, Expression, Isolation and Analysis

Extract2Chip-Bypassing Protein Purification in Drug Discovery Using Surface Plasmon Resonance

Authors: Ana C F Paiva, Ana R Lemos, Philipp Busse, Madalena T Martins, Diana O Silva, Micael C Freitas, Sandra P Santos, Filipe Freire, Evelyne J Barrey, Xavier Manival, Lisa Koetzner, Timo Heinrich, Ansgar Wegener, Ulrich Grädler, Tiago M Bandeiras, Daniel Schwarz, Pedro M F Sousa

Journal: Biosensors (Basel)

PubMed ID: 37887106

Doi: 10.3390/bios13100913

Products & Services: Proteins, Expression, Isolation and Analysis

Collagen Mimetic Peptide with a Coiled Coil Trimerization Domain Forms Fibrils Having -Period-like Structures

Authors: Faizunnahar Dewan, Michele Kirchner, Fadi Masoud, Zainab Sami, Yujia Xu

Journal: Biomacromolecules

PubMed ID: 37788665

Doi: 10.1021/acs.biomac.3c00901

Products & Services: Molecular Biology Reagents

Pyruvate kinase is post-translationally regulated by sirtuin 2 in Aedes aegypti mosquitoes

Authors: Natthida Petchampai, Jun Isoe, Prashanth Balaraman, Max Oscherwitz, Brendan H Carter, Cecilia G Sánchez, Patricia Y Scaraffia

Journal: Insect Biochem Mol Biol

PubMed ID: 37797713

Doi: 10.1016/j.ibmb.2023.104015

Products & Services: Molecular Biology Reagents

Influence of expression and purification protocols on Gα biochemical activity: kinetics of plant and mammalian G protein cycles

Authors: Timothy E Gookin, David Chakravorty, Sarah M Assmann

Journal: biorxiv

PubMed ID: 37214830

Doi: 10.1101/2023.05.10.540258

Products & Services: Molecular Biology Reagents

Ceria Nanozyme Coordination with Curcumin for Treatment of Sepsis-induced Cardiac Injury by Inhibiting Ferroptosis and Inflammation

Authors: Chenxiao Jiang, Qianzhi Shi, Jing Yang, Hao Ren, Lu Zhang, Shan Chen, Jiayi Si, Yihai Liu, Dujuan Sha, Biao Xu, Jie Ni

Journal: J Adv Res

PubMed ID: 37871772

Doi: 10.1016/j.jare.2023.10.011

Products & Services: PCR Cloning and Subcloning

Biochemical and structural characterization of a glucan synthase GFGLS2 from edible fungus Grifola frondosa to synthesize β-1, 3-glucan

Authors: Yu-Meng Yang, Xin Fu, Feng-Jie Cui, Lei Sun, Xin-Yi Zan, Wen-Jing Sun

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 37904199

Doi: 10.1186/s13068-023-02380-6

Products & Services: Codon Optimization

A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity

Authors: Andras Boeszoermenyi, Léa Bernaleau, Xudong Chen, Felix Kartnig, Min Xie, Haobo Zhang, Sensen Zhang, Maeva Delacrétaz, Anna Koren, Ann-Katrin Hopp, Vojtech Dvorak, Stefan Kubicek, Daniel Aletaha, Maojun Yang, Manuele Rebsamen, Leonhard X Heinz, Giulio Superti-Furga

Journal: Nat Commun

PubMed ID: 37863876

Doi: 10.1038/s41467-023-42070-3

Products & Services: Plasmid DNA Preparation

Serpin-1a and serpin-6 regulate the Toll pathway immune homeostasis by synergistically inhibiting the Spätzle-processing enzyme CLIP2 in silkworm, Bombyx mori

Authors: Huawei Liu, Jiahui Xu, Luoling Wang, Pengchao Guo, Zhangchen Tang, Xiaotong Sun, Xin Tang, Wei Wang, Lingyan Wang, Yang Cao, Qingyou Xia, Ping Zhao

Journal: PLoS Pathog

PubMed ID: 37851691

Doi: 10.1371/journal.ppat.1011740

Products & Services: Peptide Synthesis

KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors

Authors: Dan Lu, Yuan Chen, Min Jiang, Jie Wang, Yiting Li, Keke Ma, Wenqiao Sun, Xing Zheng, Jianxun Qi, Wenjing Jin, Yu Chen, Yan Chai, Catherine W H Zhang, Hao Liang, Shuguang Tan, George F Gao

Journal: Nat Commun

PubMed ID: 37828002

Doi: 10.1038/s41467-023-42010-1

Products & Services: Peptide Synthesis

Distribution and Degradation of Pork Filamin during Postmortem Aging

Authors: Tongyao Du, Chao Ma, Zixu Wang, Yuejing Hao, Wangang Zhang

Journal: J Agric Food Chem

PubMed ID: 37788342

Doi: 10.1021/acs.jafc.3c04208

Products & Services: Proteins, Expression, Isolation and Analysis

Benzbromarone Induces Targeted Degradation of HSP47 Protein and Improves Hypertrophic Scar Formation

Authors: Jung Gyu Park, Dong Chul Lim, Jeong Hwan Park, Seoah Park, Jongsoo Mok, Keon Wook Kang, Joonghoon Park

Journal: J Invest Dermatol

PubMed ID: 37838329

Doi: 10.1016/j.jid.2023.09.279

Products & Services: Recombinant Proteins

Molecular mechanism of sex pheromone perception in male Mythimna loreyi revealed by in vitro system

Authors: Yun-Ying Zhang, Teng-Fei Bai, Jin-Meng Guo, Zhi-Qiang Wei, Si-Ruo Liu, Yu He, Jing-Jing Ye, Qi Yan, Jin Zhang, Shuang-Lin Dong

Journal: Pest Manag Sci

PubMed ID: 37779104

Doi: 10.1002/ps.7806

Products & Services: Recombinant Proteins

How myosin VI traps its off-state, is activated and dimerizes

Authors: Louise Canon , Carlos Kikuti , Vicente J Planelles-Herrero , Tianming Lin , Franck Mayeux , Helena Sirkia , Young Il Lee , Leila Heidsieck , Léonid Velikovsky , Amandine David , Xiaoyan Liu ， Dihia Moussaoui , Emma Forest , Peter Höök , Karl J Petersen , Tomos E Morgan , Aurélie Di Cicco , Julia Sirés-Campos , Emmanuel Derivery , Daniel Lévy , Cédric Delevoye , H Lee Sweeney , Anne Houdusse

Journal: Nat Commun

PubMed ID: 37872146

Doi: 10.1038/s41467-023-42376-2

Products & Services: PCR Cloning and Subcloning

m6A methyltransferase METTL3 contributes to sympathetic hyperactivity post-MI via promoting TRAF6-dependent mitochondrial ROS production

Authors: Peijin Yang, Yu Wang, Weili Ge, Yanyan Jing, Hesheng Hu, Jie Yin, Mei Xue, Ye Wang, Xiaolu Li, Xinran Li, Yugen Shi, Jiayu Tan, Yan Li, Suhua Yan

Journal: Free Radic Biol Med

PubMed ID: 37898386

Doi: 10.1016/j.freeradbiomed.2023.10.392

Products & Services: Proteins, Expression, Isolation and Analysis

Single-cell chromatin state transitions during epigenetic memory formation

Authors: Taihei Fujimori, Carolina Rios-Martinez, Abby R Thurm, Michaela M Hinks, Benjamin R Doughty, Joydeb Sinha, Derek Le, Antonina Hafner, William J Greenleaf, Alistair N Boettiger, Lacramioara Bintu

Journal: biorxiv

PubMed ID: 37873344

Doi: 10.1101/2023.10.03.560616

Products & Services: Proteins, Expression, Isolation and Analysis

Entropy-driven reactions for controlling CRISPR/Cas12a and constructing an electrochemical biosensor for cardiac biomarkers detection

Authors: Jiaying Wang, Xianliang Wang, Bin Li, Kai Zhang, Jingyuan Mao

Journal: Mikrochim Acta

PubMed ID: 37845542

Doi: 10.1007/s00604-023-06012-6

Products & Services: Proteins, Expression, Isolation and Analysis

A retrospective study of SARS-CoV-2 seroprevalence in dogs and cats in the Community of Madrid, Spain

Authors: Lidia Sánchez-Morales, José M Sánchez-Vizcaíno, Lucas Domínguez, Sandra Barroso-Arévalo

Journal: Front Microbiol

PubMed ID: 37869682

Doi: 10.3389/fmicb.2023.1264172

Products & Services: Proteins, Expression, Isolation and Analysis

Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis

Authors: Caroline M S Cauret, Danielle C Jordan, Lindsey M Kukoly, Sarah R Burton, Emmanuela U Anele, Jacek M Kwiecien, Marie-Theres Gansauge, Sinthu Senthillmohan, Eli Greenbaum, Matthias Meyer, Marko E Horb, Ben J Evans

Journal: PLoS Genet

PubMed ID: 37792893

Doi: 10.1371/journal.pgen.1010990

Products & Services: Proteins, Expression, Isolation and Analysis

A dry powder formulation for peripheral lung delivery and absorption of an anti-SARS-CoV-2 ACE2 decoy polypeptide

Authors: Stefania Glieca, Davide Cavazzini, Elisabetta Levati, Valentina Garrapa, Angelo Bolchi, Valentina Franceschi, Simone Odau, Simone Ottonello, Gaetano Donofrio, Jonas Füner, Fabio Sonvico, Ruggero Bettini, Barbara Montanini, Francesca Buttini

Journal: Eur J Pharm Sci

PubMed ID: 37838239

Doi: 10.1016/j.ejps.2023.106609

Products & Services: Proteins, Expression, Isolation and Analysis

Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery

Authors: Alena Ivanova, Lukas Badertscher, Gwen O'Driscoll, Joakim Bergman, Euan Gordon, Anders Gunnarsson, Camilla Johansson, Michael J Munson, Cristiana Spinelli, Sara Torstensson, Liisa Vilén, Andrei Voirel, John Wiseman, Janusz Rak, Niek Dekker, Elisa Lázaro-Ibáñez

Journal: Adv Sci (Weinh)

PubMed ID: 37867228

Doi: 10.1002/advs.202304389

Products & Services: Proteins, Expression, Isolation and Analysis

Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors

Authors: Xiuxiu Zhu, Jun Chen, Wuling Li, Yanmin Xu, Juanjuan Shan, Juan Hong, Yongchun Zhao, Huailong Xu, Jiabing Ma, Junjie Shen, Cheng Qian

Journal: Cancer Res

PubMed ID: 37874330

Doi: 10.1158/0008-5472.CAN-23-1038

Products & Services: Proteins, Expression, Isolation and Analysis

X-ray crystallography study and optimization of novel benzothiophene analogs as potent selective estrogen receptor covalent antagonists (SERCAs) with improved potency and safety profiles

Authors: Chengfeng Bai, Yang Lv, Shuangshuang Xiong, Shuangjie Wu, Lin Qi, Shengnan Ren, Meiqi Zhu, Haijuan Dong, Hongtao Shen, Zhaoxing Li, Yinxue Zhu, Hui Ye, Haiping Hao, Yibei Xiao, Hua Xiang, Guoshun Luo

Journal: Bioorg Chem

PubMed ID: 37871388

Doi: 10.1016/j.bioorg.2023.106919

Products & Services: Proteins, Expression, Isolation and Analysis

CTNNBIP1-CLSTN1 functions as a housekeeping chimeric RNA and regulates cell proliferation through SERPINE2

Authors: Chen Chen, Fujun Qin, Sandeep Singh, Yue Tang, Hui Li

Journal: Cell Death Discov

PubMed ID: 37805599

Doi: 10.1038/s41420-023-01668-8

Products & Services: Proteins, Expression, Isolation and Analysis

becomes lethal to post-larvae shrimp via acquiring novel virulence factors

Authors: Shuang Liu, Wei Wang, Tianchang Jia, Lusheng Xin, Ting-Ting Xu, Chong Wang, Guosi Xie, Kun Luo, Jun Li, Jie Kong, Qingli Zhang

Journal: Microbiol Spectr

PubMed ID: 37850796

Doi: 10.1128/spectrum.00492-23

Products & Services: Proteins, Expression, Isolation and Analysis

Ablation of the GDP-fucose transporter suppresses lung cancer cell proliferation and migration by reducing expression of PD-L1

Authors: Yingshu Zhang, Nianzhu Zhang, Wanli Song, Sabiha Yousuf, Wenzhe Li

Journal: J Cancer

PubMed ID: 37928424

Doi: 10.7150/jca.84652

Products & Services: Proteins, Expression, Isolation and Analysis

generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2

Authors: Dora Buzas, Adrian H Bunzel, Oskar Staufer, Emily J Milodowski, Grace L Edmunds, Joshua C Bufton, Beatriz V Vidana Mateo, Sathish K N Yadav, Kapil Gupta, Charlotte Fletcher, Maia K Williamson, Alexandra Harrison, Ufuk Borucu, Julien Capin, Ore Francis, Georgia Balchin, Sophie Hall, Mirella V Vega, Fabien Durbesson, Srikanth Lingappa, Renaud Vincentelli, Joe Roe, Linda Wooldridge, Rachel Burt, Ross J L Anderson, Adrian J Mulholland, Jonathan Hare, Mick Bailey, Andrew D Davidson, Adam Finn, David Morgan, Jamie Mann, Joachim Spatz, Frederic Garzoni, Christiane Schaffitzel, Imre Berger

Journal: Antib Ther

PubMed ID: 38075238

Doi: 10.1093/abt/tbad024

Products & Services: Molecular Biology Reagents

Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity

Authors: Sabaria Shah, Katherine W Cook, Peter Symonds, Juliane Weißer, Anne Skinner, Abdullah Al Omari, Samantha J Paston, Ian Pike, Lindy G Durrant, Victoria A Brentville

Journal: J Immunother Cancer

PubMed ID: 37857526

Doi: 10.1136/jitc-2023-006966

Products & Services: Peptide Synthesis

Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants

Authors: Nidhi Mittal, Sahil Kumar, Raju S Rajmani, Randhir Singh, Céline Lemoine, Virginie Jakob, Sowrabha Bj, Nayana Jagannath, Madhuraj Bhat, Debajyoti Chakraborty, Suman Pandey, Aurélie Jory, Suba Soundarya Sa, Harry Kleanthous, Patrice Dubois, Rajesh P Ringe, Raghavan Varadarajan

Journal: npj Vaccines

PubMed ID: 37880298

Doi: 10.1038/s41541-023-00755-2

Products & Services: Proteins, Expression, Isolation and Analysis

Plant miRNA bol-miR159 Regulates Gut Microbiota Composition in Mice: Evidence of the Crosstalk between Plant miRNAs and Intestinal Microbes

Authors: Qin Xu, Xinshu Qin, Yi Zhang, Ke Xu, Ying Li, Yinglei Li, Bangran Qi, Yan Li, Xingbin Yang, Xingyu Wang

Journal: J Agric Food Chem

PubMed ID: 37862127

Doi: 10.1021/acs.jafc.3c06104

Products & Services: Custom DNA/RNA Oligos

Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates

Authors: Heidi Østby, Idd A Christensen, Karen Hennum, Anikó Várnai, Edith Buchinger, Siri Grandal, Gaston Courtade, Olav A Hegnar, Finn L Aachmann, Vincent G H Eijsink

Journal: Sci Rep

PubMed ID: 37833388

Doi: 10.1038/s41598-023-44278-1

Products & Services: Custom Vector Construction

Emergent properties of melanin-inspired peptide/RNA condensates

Authors: Amit Netzer, Itai Katzir, Avigail Baruch Leshem, Michal Weitman, Ayala Lampel

Journal: Proc Natl Acad Sci U S A

PubMed ID: 37871222

Doi: 10.1073/pnas.2310569120

Products & Services: Peptide Synthesis

CD8 T-cells target the Crimean-Congo haemorrhagic fever virus Gc protein to control the infection in wild-type mice

Authors: Deepashri Rao, Kimberly Meade-White, Shanna Leventhal, Evan Mihalakakos, Aaron Carmody, Heinz Feldmann, David W Hawman

Journal: EBioMedicine

PubMed ID: 37866114

Doi: 10.1016/j.ebiom.2023.104839

Products & Services: Peptide Synthesis

A biotechnological approach for the production of new protein bioplastics

Authors: Francesca De Marchis, Tania Vanzolini, Elisa Maricchiolo, Michele Bellucci, Michele Menotta, Tomas Di Mambro, Annalisa Aluigi, Andrea Zattoni, Barbara Roda, Valentina Marassi, Rita Crinelli, Andrea Pompa

Journal: Biotechnol J

PubMed ID: 37801630

Doi: 10.1002/biot.202300363

Products & Services: Molecular Biology Reagents

Inhibition of N-myristoyltransferase activity promotes androgen receptor degradation in prostate cancer

Authors: Omar Awad Alsaidan, Emmanuel Onobun, Chenming Ye, Lei Lou, Zanna Beharry, Zhong-Ru Xie, Iryna Lebedyeva, David Crich, Houjian Cai

Journal: Prostate

PubMed ID: 37905842

Doi: 10.1002/pros.24645

Products & Services: Molecular Biology Reagents

RING induces cell cycle arrest and apoptosis in human breast cancer cells by regulating the HSF1/MT2A axis

Authors: Di Liu, Yize Guo, Qin Du, Yuxuan Zhu, Ya Guo

Journal: Exp Cell Res

PubMed ID: 37797799

Doi: 10.1016/j.yexcr.2023.113795

Products & Services: Molecular Biology Reagents

Investigation of serum amyloid a within animal species focusing on the 1-25 amino acid region

Authors: Natalie G Horgan, Kendall B E Moore, Jessica S Fortin

Journal: Vet Q

PubMed ID: 37800590

Doi: 10.1080/01652176.2023.2267605

Products & Services: Peptide Synthesis

Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues

Authors: Melanie van der Woude, Carlota Davó-Martínez, Karen L Thijssen, Wim Vermeulen, Hannes Lans

Journal: Nucleic Acids Res

PubMed ID: 37522336

Doi: 10.1093/nar/gkad642

Products & Services: Proteins, Expression, Isolation and Analysis

Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease

Authors: Xingyu Zhang, Li Tang, Jiaolong Yang, Lanxia Meng, Jiehui Chen, Lingyan Zhou, Jiangyu Wang, Min Xiong, Zhentao Zhang

Journal: Nat Commun

PubMed ID: 37865646

Doi: 10.1038/s41467-023-42505-x

Products & Services: Proteins, Expression, Isolation and Analysis

Dihydropyrmidine dehydrogenase from Escherichia coli: Transient state analysis reveals both reductive activation prior to turnover and diminished substrate effector roles relative to the mammalian form

Authors: Tyler B Alt, Matthew R Hoag, Graham R Moran

Journal: Arch Biochem Biophys

PubMed ID: 37820757

Doi: 10.1016/j.abb.2023.109772

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular mechanism of decision-making in glycosaminoglycan biosynthesis

Authors: Douglas Sammon, Anja Krueger, Marta Busse-Wicher, Rhodri Marc Morgan, Stuart M Haslam, Benjamin Schumann, David C Briggs, Erhard Hohenester

Journal: Nat Commun

PubMed ID: 37828045

Doi: 10.1038/s41467-023-42236-z

Products & Services: Peptide Synthesis

High-risk histological subtype-related FAM83A hijacked FOXM1 transcriptional regulation to promote malignant progression in lung adenocarcinoma

Authors: Wei Fei, Yan Yan, Guangjun Liu, Bo Peng, Yuanyuan Liu, Qiang Chen

Journal: PeerJ

PubMed ID: 37904848

Doi: 10.7717/peerj.16306

Products & Services: Recombinant Proteins

A Small RNA, SaaS, Promotes Salmonella Pathogenicity by Regulating Invasion, Intracellular Growth, and Virulence Factors

Authors: Lin-Lin Cai, Yun-Ting Xie , Hai-Jing Hu , Xing-Lian Xu , Hu-Hu Wang , Guang-Hong Zhou

Journal: Microbiol Spectr .

PubMed ID: 36688642

Doi: 10.1128/spectrum.02938-22

Products & Services: Proteins, Expression, Isolation and Analysis

UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence

Authors: Alessio De Magis, Michaela Limmer, Venkat Mudiyam, David Monchaud, Stefan Juranek, Katrin Paeschke

Journal: Nat Commun

PubMed ID: 37872164

Doi: 10.1038/s41467-023-42494-x

Products & Services: Proteins, Expression, Isolation and Analysis

Requires the Type II Secretion System for Pathogenicity and Survival in Grapevine

Authors: Brian Ingel, Claudia Castro, Lindsey Burbank, Nancy Her, N Itzel De Anda, Hannah Way, Peng Wang, M Caroline Roper

Journal: Mol Plant Microbe Interact

PubMed ID: 37188464

Doi: 10.1094/MPMI-03-23-0027-R

Products & Services: Gene Synthesis

Aggregative adherence fimbriae form compact structures as seen by SAXS

Authors: Rie Jønsson, Alexander Björling, Søren Roi Midtgaard, Grethe Vestergaard Jensen, Nicholas Skar-Gislinge, Lise Arleth, Steve Matthews, Karen Angeliki Krogfelt, Håvard Jenssen

Journal: Sci Rep

PubMed ID: 37783694

Doi: 10.1038/s41598-023-42079-0

Products & Services: Proteins, Expression, Isolation and Analysis

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