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Immunoglobulin G subclasses confer protection against  bloodstream dissemination through distinct mechanisms in mouse models
Authors: Xinhai Chen, Haley Gula, Tonu Pius, Chong Ou, Margaryta Gomozkova, Lai-Xi Wang, Olaf Schneewind, Dominique Missiakas
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36972444
Doi: 10.1073/pnas.2220765120
Targeted DNA integration in human cells without double-strand breaks using CRISPR RNA-guided transposases
Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg
Journal: biorxiv
PubMed ID: 36993517
Doi: 10.1101/2023.03.17.533036
Products & Services: Molecular Biology Reagents   
KRT5 mutation regulate melanin metabolism through notch signalling pathway between keratinocytes and melanocytes
Authors: Weixue Jia, Yuanyuan Zhang, Xue Wang, Lingling Luo, Heng Sun, Yiqun Jiang, Jianbo Wang, Qiuxia Mao, Youming Guo, Lingzhuo Kong, Ran Mo, Chengrang Li
Journal: Exp Dermatol
PubMed ID: 36809573
Doi: 10.1111/exd.14761
Products & Services: Molecular Biology Reagents   
Conservation and divergence of flg22, pep1 and nlp20 in activation of immune response and inhibition of root development
Authors: Yan Huang, Junmei Cui, Meng Li, Rongqian Yang, Yang Hu, Xiaosong Yu, Ying Chen, Qiqi Wu, Huipeng Yao, Guozhi Yu, Jinya Guo, Huaiyu Zhang, Shuang Wu, Yi Cai
Journal: Plant Sci
PubMed ID: 36963637
Doi: 10.1016/j.plantsci.2023.111686
Products & Services: Peptide Synthesis   
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma
Authors: Lucia Morgado-Palacin, Jessie A Brown, Thomas F Martinez, Juana M Garcia-Pedrero, Farhad Forouhar, S Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodriguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F Fernandez, Mario F Fraga, Arianna L Kim, Jorge Santos-Juanes, David M Owens, Juan P Rodrigo, Alan Saghatelian, Adolfo A Ferrando
Journal: Nat Commun
PubMed ID: 36899004
Doi: 10.1038/s41467-023-36713-8
Products & Services: DNA Sequencing   
Colorectal cancer-derived extracellular vesicles containing HSP70 enhance macrophage phagocytosis by up-regulating MARCO expression
Authors: Yu Sun, Wenjun Xiao, Yang Yu, Yuchen Jiang, Zhijie Xiao, Defa Huang, Tianyu Zhong, Jiang Li, Xi Xiang, Yulong He, Zhigang Li
Journal: Exp Cell Res
PubMed ID: 36958650
Doi: 10.1016/j.yexcr.2023.113565
Products & Services: Gene Synthesis   
Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina
Authors: Mahfuz Khan, Amad Diop, Erick Gbodossou, Peng Xiao, Morgan Coleman, Kenya De Barros, Hao Duong, Vincent C Bond, Virginia Floyd, Kofi Kondwani, Valerie Montgomery Rice, Sandra Harris-Hooker, Francois Villinger, Michael D Powell
Journal: Virol J
PubMed ID: 36949470
Doi: 10.1186/s12985-023-02010-5
Products & Services: Molecular Biology Reagents   
Identification of tagged glycans with a protein nanopore
Authors: Minmin Li, Yuting Xiong, Yuchen Cao, Chen Zhang, Yuting Li, Hanwen Ning, Fan Liu, Han Zhou, Xiaonong Li, Xianlong Ye, Yue Pang, Jiaming Zhang, Xinmiao Liang, Guangyan Qing
Journal: Nat Commun
PubMed ID: 36977665
Doi: 10.1038/s41467-023-37348-5
Products & Services: Codon Optimization   
Nuclease activity of Plasmodium falciparum Alba family protein PfAlba3
Authors: Chinmoy Banerjee, Shiladitya Nag, Manish Goyal, Debanjan Saha, Asim Azhar Siddiqui, Somnath Mazumder, Subhashis Debsharma, Saikat Pramanik, Uday Bandyopadhyay
Journal: Cell Rep
PubMed ID: 36947546
Doi: 10.1016/j.celrep.2023.112292
Arc ubiquitination regulates endoplasmic reticulum-mediated Ca release and CaMKII signaling
Authors: Mohammad A Ghane, Wei Wei, Dina W Yakout, Zachary D Allen, Cassandra L Miller, Bin Dong, Jenny J Yang, Ning Fang, Angela M Mabb
Journal: Front Cell Neurosci
PubMed ID: 36998269
Doi: 10.3389/fncel.2023.1091324
The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function
Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, Joke Vanden Berghe, Niek Sanders, Ben Wielockx, Rudi Beyaert, Claude Libert
Journal: Front Immunol
PubMed ID: 37006237
Doi: 10.3389/fimmu.2023.1124011
Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r
Authors: Brianne E Hoglin, Marin V Miner, Ugumuur Erbenebayar, Ciaran A Shaughnessy, Robert M Dores
Journal: Gen Comp Endocrinol
PubMed ID: 36996927
Doi: 10.1016/j.ygcen.2023.114278
Cryopreservation modifies the distribution of the prostate-derived lectin SL15 on the llama (Lama glama) sperm
Authors: Renato Zampini, Ximena A Castro-González, Micaela Scandura, Luciana M Sari, Ana V Diaz, Alfredo Martin, Martin E Argañaraz, Silvana A Apichela
Journal: Theriogenology
PubMed ID: 36933286
Doi: 10.1016/j.theriogenology.2023.03.006
Products & Services: Molecular Biology Reagents   
High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion
Authors: Telmo O Paiva, Joan A Geoghegan, Yves F Dufrêne
Journal: Commun Biol
PubMed ID: 36944849
Doi: 10.1038/s42003-023-04660-1
Products & Services: Peptide Synthesis   
Programmable protein delivery with a bacterial contractile injection system
Authors: Joseph Kreitz, Mirco J Friedrich, Akash Guru, Blake Lash, Makoto Saito, Rhiannon K Macrae, Feng Zhang
Journal: Nature
PubMed ID: 36991127
Doi: 10.1038/s41586-023-05870-7
Products & Services: Gene Synthesis   
Structural basis of peptide recognition and activation of endothelin receptors
Authors: Yujie Ji, Jia Duan, Qingning Yuan, Xinheng He, Gong Yang, Shengnan Zhu, Kai Wu, Wen Hu, Tianyu Gao, Xi Cheng, Hualiang Jiang, H Eric Xu, Yi Jiang
Journal: Nat Commun
PubMed ID: 36882417
Doi: 10.1038/s41467-023-36998-9
Products & Services: Custom DNA/RNA Oligos   
Development of an efficient method for selection of stable cell pools for protein expression and surface display with Expi293F cells
Authors: Chuan Chen, Zening Wang, Zehua Sun, Wei Li, Dimiter S Dimitrov
Journal: Cell Biochem Funct
PubMed ID: 36864545
Doi: 10.1002/cbf.3787
Products & Services: Recombinant Proteins   
JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension
Authors: Chen Zhang, Yue Sun, Yingying Guo, Jingjing Xu, Haiyan Zhao
Journal: Cell Death Discov
PubMed ID: 36934091
Doi: 10.1038/s41420-023-01390-5
Products & Services: Catalog Peptides   
Relative role of border restrictions, case finding and contact tracing in controlling SARS-CoV-2 in the presence of undetected transmission: a mathematical modelling study
Authors: Rachael Pung, Hannah E Clapham, Timothy W Russell, Vernon J Lee, Adam J Kucharski
Journal: BMC Med
PubMed ID: 36927576
Doi: 10.1186/s12916-023-02802-0
The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity
Authors: Caroline Bost, Julia Hartlaub, Vinícius Pinho Dos Reis, Thomas Strecker, Nabil G Seidah, Martin H Groschup, Sandra Diederich, Kerstin Fischer
Journal: Virus Res
PubMed ID: 36948228
Doi: 10.1016/j.virusres.2023.199099
Rare Catechol--methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets
Authors: Fia B Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Journal: Biochemistry
PubMed ID: 36976271
Doi: 10.1021/acs.biochem.3c00008
Nanotopographic micro-nano forces finely tune the conformation of macrophage mechanosensitive membrane protein integrin β to manipulate inflammatory responses
Authors: Yuanlong Guo, Yong Ao, Chen Ye, Ruidi Xia, Jiaomei Mi, Zhengjie Shan, Mengru Shi, Lv Xie, Zetao Chen
Journal: Nano Res
PubMed ID: 37359074
Doi: 10.1007/s12274-023-5550-0
Cytokinin-responsive MdTCP17 interacts with MdWOX11 to repress adventitious root primordium formation in apple rootstocks
Authors: Jiangping Mao, Chundong Niu, Ke Li, Li Fan, Zhimin Liu, Shaohuan Li, Doudou Ma, Muhammad Mobeen Tahir, Libo Xing, Caiping Zhao, Juanjuan Ma, Na An, Mingyu Han, Xiaolin Ren, Dong Zhang
Journal: Plant Cell
PubMed ID: 36544357
Doi: 10.1093/plcell/koac369
Products & Services: Monoclonal Antibody Services   
Uman-type neurofilament light antibodies are effective reagents for the imaging of neurodegeneration
Authors: Gerry Shaw, Irina Madorsky, Ying Li, YongSheng Wang, Marda Jorgensen, Sabhya Rana, David D Fuller
Journal: Brain Commun
PubMed ID: 37091583
Doi: 10.1093/braincomms/fcad067
Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective
Authors: Przemyslaw Grygier, Katarzyna Pustelny, Jakub Nowak, Przemyslaw Golik, Grzegorz M Popowicz, Oliver Plettenburg, Grzegorz Dubin, Filipe Menezes, Anna Czarna
Journal: J Med Chem
PubMed ID: 36883902
Doi: 10.1021/acs.jmedchem.2c01887
Products & Services: Combinatorial DNA Libraries   
Structural basis for motilin and erythromycin recognition by motilin receptor
Authors: Chongzhao You, Yumu Zhang, Youwei Xu, Peiyu Xu, Zhen Li, Huadong Li, Sijie Huang, Zecai Chen, Jingru Li, H Eric Xu, Yi Jiang
Journal: Science Advances
PubMed ID: 36921049
Doi: 10.1126/sciadv.ade9020
Products & Services: Peptide Synthesis   
Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
Authors: Tong Han, Xujun Wang, Sailing Shi, Wubing Zhang, Jue Wang, Qiu Wu, Ziyi Li, Jingxin Fu, Rongbin Zheng, Jiamin Zhang, Qin Tang, Peng Zhang, Chenfei Wang
Journal: cancer immunology research
PubMed ID: 36629846
Doi: 10.1158/2326-6066.CIR-22-0056
Plasticity in airway smooth muscle differentiation during mouse lung development
Authors: Katharine Goodwin, Bezia Lemma, Pengfei Zhang, Adam Boukind, Celeste M Nelson
Journal: Dev Cell
PubMed ID: 36868232
Doi: 10.1016/j.devcel.2023.02.002
Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine
Authors: Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J Sigal, Renhuan Xu, Huabin Zhu
Journal: Front Immunol
PubMed ID: 37033973
Doi: 10.3389/fimmu.2023.1126392
Products & Services: Peptide Synthesis   
Mapping the conformational landscape of the stimulatory heterotrimeric G protein
Authors: Shuya Kate Huang, Louis-Philippe Picard, Rima S M Rahmatullah, Aditya Pandey, Ned Van Eps, Roger K Sunahara, Oliver P Ernst, Adnan Sljoka, R Scott Prosser
Journal: Nat Struct Mol Biol
PubMed ID: 36997760
Doi: 10.1038/s41594-023-00957-1
Products & Services: Molecular Biology Reagents   
Structure-activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor
Authors: Yufang Deng, Claudia V Perez Almeria, Lieke van Gijzel, Kay Schaller, Line Vedel, David E Gloriam, Trond Ulven, Hans Bräuner-Osborne
Journal: Basic Clin Pharmacol Toxicol
PubMed ID: 36930875
Doi: 10.1111/bcpt.13861
Products & Services: Molecular Biology Reagents   
Vimentin Is an Attachment Receptor for Mycoplasma pneumoniae P1 Protein
Authors: Kailan Peng, Yating Liao, Xia Li, Dongdong Zeng, Youyuan Ye, Li Chen, Zhuo Zeng, Yanhua Zeng
Journal: Microbiol Spectr
PubMed ID: 36912679
Doi: 10.1128/spectrum.04489-22
Products & Services: Molecular Biology Reagents   
Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming
Authors: Allan C deCamp, Martin M Corcoran, William J Fulp, Jordan R Willis, Christopher A Cottrell, Daniel L V Bader, Oleksandr Kalyuzhniy, David J Leggat, Kristen W Cohen, Ollivier Hyrien, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R Plyler, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E Whaley, Aaron Seese, Joshua Brand, Alexis M Ruppel, Wesley Hoyland, Celia R Mahoney, Alberto Cagigi, Alison Taylor, David M Brown, David R Ambrozak, Troy Sincomb, Tina-Marie Mullen, Janine Maenza, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Mario Roederer, David Diemert, Richard A Koup, Dagna S Laufer, Juliana M McElrath, Adrian B McDermott, Gunilla B Karlsson Hedestam, William R Schief
Journal: medrxiv
PubMed ID: 36993183
Doi: 10.1101/2023.03.10.23287126
Products & Services: Molecular Biology Reagents   
Impact of homologous and heterologous boosters in neutralizing antibodies titers against SARS-CoV-2 Omicron in solid-organ transplant recipients
Authors: Aracelly Gaete-Argel, Vicente Saavedra-Alarcón, Denis Sauré, Luis Alonso-Palomares, Mónica L Acevedo, Marion Alarcón, Susan M Bueno, Alexis M Kalergis, Ricardo Soto-Rifo, Fernando Valiente-Echeverría, Claudia P Cortes
Journal: Front Immunol
PubMed ID: 36999018
Doi: 10.3389/fimmu.2023.1135478
Products & Services: Molecular Biology Reagents   
A short-chain carbonyl reductase mutant is an efficient catalyst in the production of (R)-1,3-butanediol
Authors: Xiaoyan Guo, Yunfang Gao, Fangzheng Liu, Yong Tao, Haibo Jin, Jianjun Wang, Sheng Wu
Journal: Microb Biotechnol
PubMed ID: 36946330
Doi: 10.1111/1751-7915.14249
Products & Services: Molecular Biology Reagents   
Production of neutralizing antibody fragment variants in the cytoplasm of E coli for rapid screening: SARS-CoV-2 a case study
Authors: Aatir A Tungekar, Rosario Recacha, Lloyd W Ruddock
Journal: Sci Rep
PubMed ID: 36927743
Doi: 10.1038/s41598-023-31369-2
Products & Services: Molecular Biology Reagents   
Identification of specific and shared epitopes at the extreme N-terminal VP1 of Coxsackievirus A4, A2 and A5 by monoclonal antibodies
Authors: Yu-Xuan Tian, Wei-Ping Jin, Zhen-Ni Wei, Shi-Yun Lv, Meng-Jun Wang, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Shuo Shen
Journal: Virus Res
PubMed ID: 36805409
Doi: 10.1016/j.virusres.2023.199074
Products & Services: Peptide Synthesis   
PF-D-Trimer, a protective SARS-CoV-2 subunit vaccine: immunogenicity and application
Authors: Zhihao Zhang, Jinhu Zhou, Peng Ni, Bing Hu, Normand Jolicoeur, Shuang Deng, Qian Xiao, Qian He, Gai Li, Yan Xia, Mei Liu, Cong Wang, Zhizheng Fang, Nan Xia, Zhe-Rui Zhang, Bo Zhang, Kun Cai, Yan Xu, Binlei Liu
Journal: npj Vaccines
PubMed ID: 36922524
Doi: 10.1038/s41541-023-00636-8
Products & Services: Gene Synthesis   
Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway
Authors: Yu Jiang, Xiyuan Li, Fenghui Qian, Bingbing Sun, Xiyuan Wang, Yan Zhang, Deqiang Zhang, Meiyu Geng, Zuoquan Xie, Sheng Yang
Journal: Research (Wash D C)
PubMed ID: 37011280
Doi: 10.34133/research.0102
Products & Services: Gene Synthesis   
The diurnal salivary glands transcriptome of Dermacentor nuttalli from the first four days of blood feeding
Authors: Hejia Ma, Yanjun Lao, Susu Liu, Jingkai Ai, Xue Sun, Wei Zhang, Ming Kang, Jixu Li, Yali Sun
Journal: Ticks Tick Borne Dis
PubMed ID: 37001418
Doi: 10.1016/j.ttbdis.2023.102178
Products & Services: PCR Cloning and Subcloning   
Ferulic Acid Alleviates Hepatic Lipid Accumulation and Inflammation by Improving Proximal and Distal Intestinal Barriers in NAFLD Mice
Authors: Jiaojiao Fu, Jingyan Yang, Liying He, Caixia Yang, Jing He, Yanan Hua, Jinlin Guo, Sijing Liu
Journal: Tohoku J Exp Med
PubMed ID: 36927682
Doi: 10.1620/tjem.2023.J023
Products & Services: Molecular Biology Reagents   
Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence
Authors: Zhenzhen Xiong, Nan Zhang, Liru Xu, Zhiduo Deng, Jarukitt Limwachiranon, Yaojie Guo, Yi Han, Wei Yang, Daniel H Scharf
Journal: Microbiol Spectr
PubMed ID: 36916906
Doi: 10.1128/spectrum.03508-22
Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases
Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg
Journal: Nat Biotechnol
PubMed ID: 36991112
Doi: 10.1038/s41587-023-01748-1
Products & Services: Gene Synthesis   
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins
Authors: Shuang Zhang, Sheng-Li Ming, Lei Zeng, Lu-Fang Wang, Chao Zhang, He-Shui Zhu, Guo-Yu Yang, Gai-Ping Zhang, Bei-Bei Chu, Jiang Wang
Journal: J Med Virol
PubMed ID: 36807585
Doi: 10.1002/jmv.28591
Novel multi-epitope vaccine against bovine brucellosis: approach from immunoinformatics to expression
Authors: Somayyeh Rahimnahal, Shahnaz Yousefizadeh, Yahya Mohammadi
Journal: J Biomol Struct Dyn
PubMed ID: 36927475
Doi: 10.1080/07391102.2023.2188962
Entropy-driven assisted T7 RNA polymerase amplification-activated CRISPR/Cas13a activity for SARS-CoV-2 detection in human pharyngeal swabs and environment by an electrochemiluminescence biosensor
Authors: Jihua Wei, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao
Journal: J Hazard Mater
PubMed ID: 36965355
Doi: 10.1016/j.jhazmat.2023.131268
Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health
Authors: Sukrit Srivastava, Sonia Verma, Mohit Kamthania, Ajay Kumar Saxena, Kailash C Pandey, Veena Pande, Michael Kolbe
Journal: PLoS ONE
PubMed ID: 36920996
Doi: 10.1371/journal.pone.0282580
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge
Authors: Ebony N Gary, Nicholas J Tursi, Bryce M Warner, Gina Cuismano, Jennifer Connors, Elizabeth M Parzych, Bryan D Griffin, Matthew R Bell, Ali R Ali, Drew Frase, Casey E Hojecki, Gabriela A Canziani, Irwin Chaiken, Toshitha Kannan, Estella Moffat, Carissa Embury-Hyatt, Sarah K Wooton, Andrew Kossenkov, Ami Patel, Darwyn Kobasa, Michele A Kutzler, Elias K Haddad, David B Weiner
Journal: Front Immunol
PubMed ID: 36999023
Doi: 10.3389/fimmu.2023.1138609
Products & Services: Molecular Biology Reagents   
Active Site Aromatic Residues Play a Dual Role in the Substrate Interaction and Protein Structure in Functional Dimers of CYP121A1 of
Authors: Christopher S Campomizzi, Amit Kumar, Patil Pranita Uttamrao, Jack J Stallone, George E Ghanatios, Thenmalarchelvi Rathinavelan, D Fernando Estrada
Journal: ACS Infect Dis
PubMed ID: 36976833
Doi: 10.1021/acsinfecdis.2c00531
High Autophagy Patterns in Swelling Platelets During Apheresis Platelet Storage
Authors: Lu Yu, Shifang Yu, Yunlei He, Gang Deng, Qiang Li
Journal: Indian J Hematol Blood Transfus
PubMed ID: 37790743
Doi: 10.1007/s12288-023-01638-1

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