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Structure of the core human NADPH oxidase NOX2

Authors: Sigrid Noreng, Naruhisa Ota, Yonglian Sun, Hoangdung Ho, Matthew Johnson, Christopher P Arthur, Kellen Schneider, Isabelle Lehoux, Christopher W Davies, Kyle Mortara, Kit Wong, Dhaya Seshasayee, Matthieu Masureel, Jian Payandeh, Tangsheng Yi, James T Koerber

Journal: Nat Commun

PubMed ID: 36241643

Doi: 10.1038/s41467-022-33711-0

Products & Services: Gene Synthesis

Target RNA activates the protease activity of Craspase to confer antiviral defense

Authors: Xi Liu, Laixing Zhang, Hao Wang, Yu Xiu, Ling Huang, Zhengyu Gao, Ningning Li, Feixue Li, Weijia Xiong, Teng Gao, Yi Zhang, Maojun Yang, Yue Feng

Journal: Mol Cell

PubMed ID: 36306795

Doi: 10.1016/j.molcel.2022.10.007

Products & Services: Gene Synthesis

Deciphering the virulence potential of Listeria monocytogenes in the Norwegian meat and salmon processing industry by combining whole genome sequencing and in vitro data

Authors: Eva Wagner, Annette Fagerlund, Sarah Thalguter, Merete Rusås Jensen, Even Heir, Trond Møretrø, Birgitte Moen, Solveig Langsrud, Kathrin Rychli

Journal: Int J Food Microbiol

PubMed ID: 36240603

Doi: 10.1016/j.ijfoodmicro.2022.109962

Products & Services: Proteins, Expression, Isolation and Analysis

TMT-Based Quantitative Proteomic Analysis Reveals Downregulation of ITGAL and Syk by the Effects of Cycloastragenol in OVA-Induced Asthmatic Mice

Authors: Xueyi Zhu, Baojun Liu, Zhenhui Ruan, Mengmeng Chen, Congcong Li, Hanlin Shi, Xi Huang, Hang Yu, Yaolong Zhou, Hehua Zhu, Jing Sun, Ying Wei, Weifang Xu, Jingcheng Dong

Journal: Oxid Med Cell Longev

PubMed ID: 36329800

Doi: 10.1155/2022/6842530

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular Effects of Iodine-Biofortified Lettuce in Human Gastrointestinal Cancer Cells

Authors: Olga Sularz, Aneta Koronowicz, Cayla Boycott, Sylwester Smoleń, Barbara Stefanska

Journal: Nutrients

PubMed ID: 36296971

Doi: 10.3390/nu14204287

Products & Services: Proteins, Expression, Isolation and Analysis

Photoprotective Effects of Cannabidiol against Ultraviolet-B-Induced DNA Damage and Autophagy in Human Keratinocyte Cells and Mouse Skin Tissue

Authors: Yanmei Li, Dan Hao, Danfeng Wei, Yue Xiao, Lian Liu, Xiaoxue Li, Lian Wang, Yu Gan, Wei Yan, Bowen Ke, Xian Jiang

Journal: Molecules

PubMed ID: 36235276

Doi: 10.3390/molecules27196740

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular characterization of peptidoglycan recognition proteins from Mytilus coruscus

Authors: Zhi Liao, Zongxin Yang, Ying Wang, Jianyu He, Zhijiang He, Xiaolin Zhang, Isabella Buttino, Pengzhi Qi, Meihua Fan, Baoying Guo, Xiaojun Yan, Menglan He

Journal: Fish Shellfish Immunol

PubMed ID: 36272520

Doi: 10.1016/j.fsi.2022.10.018

Products & Services: Proteins, Expression, Isolation and Analysis

Regulation of Prolactin Release at the End Stage of Chicken Embryogenesis

Authors: Norio Kansaku, Shin Wakui, Tomohiro Sasanami, Takeshi Ohkubo

Journal: J Poult Sci

PubMed ID: 36382060

Doi: 10.2141/jpsa.0220023

Products & Services: Proteins, Expression, Isolation and Analysis

TBC1D18 is a Rab5-GAP that coordinates endosome maturation together with Mon1

Authors: Shu Hiragi, Takahide Matsui, Yuriko Sakamaki, Mitsunori Fukuda

Journal: J Cell Biol

PubMed ID: 36197338

Doi: 10.1083/jcb.202201114

Products & Services: Proteins, Expression, Isolation and Analysis

The diurnal emission of floral scent in Oncidium hybrid orchid is controlled by CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) through the direct regulation on terpene synthase

Authors: Chao-Wei Yeh, Hui-Qin Zhong, Yung-Feng Ho, Zhi-Hong Tian, Kai-Wun Yeh

Journal: BMC Plant Biol

PubMed ID: 36195835

Doi: 10.1186/s12870-022-03850-z

Products & Services: Proteins, Expression, Isolation and Analysis

Highly efficient hybridoma generation and screening strategy for anti-PD-1 monoclonal antibody development

Authors: Tanapati Phakham, Chatikorn Boonkrai, Tossapon Wongtangprasert, Thittaya Audomsun, Chadaporn Attakitbancha, Pijitra Saelao, Phijitra Muanwien, Sarintip Sooksai, Nattiya Hirankarn, Trairak Pisitkun

Journal: Sci Rep

PubMed ID: 36273231

Doi: 10.1038/s41598-022-20560-6

Products & Services: Stable Cell Lines

Hydrogen-bonds mediate liquid-liquid phase separation of mussel derived adhesive peptides

Authors: Qi Guo, Guijin Zou, Xuliang Qian, Shujun Chen, Huajian Gao, Jing Yu

Journal: Nat Commun

PubMed ID: 36182948

Doi: 10.1038/s41467-022-33545-w

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Ultra-sensitive molecular detection of gene fusions from RNA using ASPYRE

Authors: Eleanor R Gray, Justyna M Mordaka, Efthimia R Christoforou, Kristine von Bargen, Nicola D Potts, Christina Xyrafaki, Ana-Luisa Silva, Magdalena Stolarek-Januszkiewicz, Katarzyna Anton, Paulina K Powalowska, Simonetta Andreazza, Alessandro Tomassini, Rebecca N Palmer, Aishling Cooke, Robert J Osborne, Barnaby W Balmforth

Journal: BMC Med Genomics

PubMed ID: 36224552

Doi: 10.1186/s12920-022-01363-0

Products & Services: Custom DNA/RNA Oligos

An experimental test of the nicotinic hypothesis of COVID-19

Authors: Nicole E Godellas, Gisela D Cymes, Claudio Grosman

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36279466

Doi: 10.1073/pnas.2204242119

Products & Services: Catalog Peptides

Long noncoding RNA-mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer

Authors: Zhenbo Tu, Yi Hu, Devesh Raizada, Mahmoud A Bassal, Daniel G Tenen, Antoine E Karnoub

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36269860

Doi: 10.1073/pnas.2203180119

Products & Services: Mammalian Expression

Presence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibodies Among Vietnamese Healthcare Workers by Dosing Interval for ChAdOx1 nCoV-19 Vaccine

Authors: Dien M Vu, Diep T B Vu, Thuy T T Do, Allison E Olmsted, Bach H Dao, Truc T Thai, Chi L Nguyen, Nhung T T Le, Tuan A Le, Hien T T Bui, Thach N Pham, Matthew R Moore

Journal: Clin Infect Dis

PubMed ID: 35723271

Doi: 10.1093/cid/ciac493

Products & Services: Recombinant Proteins

AlphaFold version 20 elucidates the binding mechanism between VIPR2 and KS-133, and reveals an S-S bond (Cys-Cys) formation of functional significance for VIPR2

Authors: Kotaro Sakamoto, Satoshi Asano, Yukio Ago, Takatsugu Hirokawa

Journal: Biochem Biophys Res Commun

PubMed ID: 36332470

Doi: 10.1016/j.bbrc.2022.10.071

Products & Services: Plasmid DNA Preparation

Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease

Authors: Hangchen Hu, Qian Wang, Haixia Su, Qiang Shao, Wenfeng Zhao, Guofeng Chen, Minjun Li, Yechun Xu

Journal: Angew Chem Int Ed Engl

PubMed ID: 36308706

Doi: 10.1002/anie.202212378

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Recombinant acetylxylan esterase of Halalkalibacterium halodurans NAH-Egypt: molecular and biochemical study.

Authors: Amira M Embaby , Hoda E Mahmoud

Journal: AMB Express .

PubMed ID: 36289146

Doi: A10.1186/s13568-022-01476-w.

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Systemic and Mucosal Humoral Immune Response Induced by Three Doses of the BNT162b2 SARS-CoV-2 mRNA Vaccines

Authors: Roberta Mancuso, Simone Agostini, Lorenzo Agostino Citterio, Debora Chiarini, Maria Antonia Santangelo, Mario Clerici

Journal: Vaccines (Basel)

PubMed ID: 36298514

Doi: 10.3390/vaccines10101649

Products & Services: Serology SARS-Cov-2 detection kits

PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PDL1 bias-dependent way

Authors: Xiaolu Yu, Yiru Long , Binfan Chen , Yongliang Tong , Mengwen Shan , Xiaomin Jia , Chao Hu , Meng Liu , Ji Zhou , Feng Tang , Henglei Lu , Runqiu Chen , Pan Xu , Wei Huang , Jin Ren , Yakun Wan , Jianhua Sun , Jia Li , Guangyi Jin , Likun Gong

Journal: J Immunother Cancer .

PubMed ID: 36253000

Doi: 10.1136/jitc-2022-004590

Products & Services: Recombinant Proteins

PCDetection: PolyA-CRISPR/Cas12a-based miRNA detection without PAM restriction

Authors: Mingtian Zhong , Kaizhao Chen , Wenjun Sun , Xiangyang Li , Shisheng Huang , Qingzhou Meng , Bo Sun , Xingxu Huang , Xinjie Wang , Xiaodong Ma , Peixiang Ma

Journal: Biosens Bioelectron

PubMed ID: 35797934

Doi: 10.1016/j.bios.2022.114497

Products & Services: Gene Synthesis

Duration of antiretroviral therapy impacts the degree of residual SIV infection in the gut in long-term non-progressing Chinese rhesus macaques

Authors: Antonio Solis-Leal, Ann-Marie May, Mahesh Mohan, Jason P Dufour, Binhua Ling

Journal: J Med Virol

PubMed ID: 36181356

Doi: 10.1002/jmv.28185

Products & Services: Proteins, Expression, Isolation and Analysis

Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy

Authors: Wentao Fan, Chenchen Ding, Shuhui Liu, Xiaona Gao, Xiaofei Shen, Marthe De Boevre, Zhangshan Gao, Mengcong Li, Shuo Zhang, Yufan Miao, Wenxian Guan, Guangliang Liu, Liping Yan, Sarah De Saeger, Suquan Song

Journal: Cell Rep

PubMed ID: 36223738

Doi: 10.1016/j.celrep.2022.111454

Products & Services: Proteins, Expression, Isolation and Analysis

Fructose-6-phosphate-2-kinase/fructose-2,6-bisphosphatase regulates energy metabolism and synthesis of storage products in developing rice endosperm

Authors: Xiaoli Chen , Yi Ji , Weiying Zhao , Huanying Niu , Xue Yang , Xiaokang Jiang , Yipeng Zhang , Jie Lei , Hang Yang , Rongbo Chen , Chuanwei Gu , Hongyi Xu , Hui Dong , Erchao Duan , Xuan Teng , Yunlong Wang , Yuanyan Zhang , Wenwei Zhang , Yihua Wang , Jianmin Wan

Journal: Plant Sci

PubMed ID: 36270512

Doi: 10.1016/j.plantsci.2022.111503

Products & Services: Proteins, Expression, Isolation and Analysis

The Detection of Immunity against WT1 and SMAD4 of EpCAM Cancer Cells in Malignant Pleural Effusion

Authors: Terutsugu Koya, Yo Niida, Misa Togi, Kenichi Yoshida, Takuya Sakamoto, Hiroki Ura, Sumihito Togi, Tomohisa Kato, Sohsuke Yamada, Haruo Sugiyama, Shigeo Koido, Shigetaka Shimodaira

Journal: Int J Mol Sci

PubMed ID: 36293034

Doi: 10.3390/ijms232012177

Products & Services: Peptide Synthesis

Isobutanol production by combined and metabolic engineering

Authors: Mamta Gupta, Matthew Wong, Kamran Jawed, Kamil Gedeon, Hannah Barrett, Marcelo Bassalo, Clifford Morrison, Danish Eqbal, Syed Shams Yazdani, Ryan T Gill, Jiaqi Huang, Marc Douaisi, Jonathan Dordick, Georges Belfort, Mattheos A G Koffas

Journal: Metab Eng Commun

PubMed ID: 36325486

Doi: 10.1016/j.mec.2022.e00210

Products & Services: Plasmid DNA Preparation

Multifunctional chemical inhibitors of the florigen activation complex discovered by structure-based high-throughput screening

Authors: Ken-Ichiro Taoka, Ikumi Kawahara, Shoko Shinya, Ken-Ichi Harada, Eiki Yamashita, Zenpei Shimatani, Kyoko Furuita, Tomoaki Muranaka, Tokitaka Oyama, Rie Terada, Atsushi Nakagawa, Toshimichi Fujiwara, Hiroyuki Tsuji, Chojiro Kojima

Journal: Plant J

PubMed ID: 36288411

Doi: 10.1111/tpj.16008

Products & Services: Peptide Synthesis

The large plasmid carried class 1 integrons mediated multidrug resistance of foodborne Indiana

Authors: Xuefeng Wang, Tian Wang, Mengjiao Guo, Chengcheng Zhang, Zongyi Bo, Yantao Wu, Guoxiang Chao

Journal: Front Microbiol

PubMed ID: 36312970

Doi: 10.3389/fmicb.2022.991326

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Development and characterization of a new monoclonal antibody against SARS-CoV-2 NSP12 (RdRp)

Authors: Wen Meng, Siying Guo, Simon Cao, Masahiro Shuda, Lindsey R Robinson-McCarthy, Kevin R McCarthy, Yoko Shuda, Alberto E Paniz Mondolfi, Clare Bryce, Zachary Grimes, Emilia M Sordillo, Carlos Cordon-Cardo, Pengfei Li, Hu Zhang, Stanley Perlman, Haitao Guo, Shou-Jiang Gao, Yuan Chang, Patrick S Moore

Journal: J Med Virol

PubMed ID: 36271490

Doi: 10.1002/jmv.28246

Products & Services: Peptide Synthesis

A simple thermodynamic description of phase separation of Nup98 FG domains

Authors: Sheung Chun Ng, Dirk Görlich

Journal: Nat Commun

PubMed ID: 36257947

Doi: 10.1038/s41467-022-33697-9

Products & Services: Bacterial Expression

A novel rhesus macaque model of Huntington's disease recapitulates key neuropathological changes along with motor and cognitive decline

Authors: Alison R Weiss, William A Liguore, Kristin Brandon, Xiaojie Wang, Zheng Liu, Jacqueline S Domire, Dana Button, Sathya Srinivasan, Christopher D Kroenke, Jodi L McBride

Journal: Elife

PubMed ID: 36205397

Doi: 10.7554/eLife.77568

Products & Services: Plasmid DNA Preparation

Comparative proteomic analysis reveals novel insights into the continuous cropping induced response in Scrophularia ningpoensis

Authors: Jiachen Sun, Xuejiao Li, Zhuo Qu, Huairui Wang, Yao Cheng, Shengjie Dong, Hui Zhao

Journal: J Sci Food Agric

PubMed ID: 36271763

Doi: 10.1002/jsfa.12284

Products & Services: Proteins, Expression, Isolation and Analysis

A dataset comprised of binding interactions for 104,972 antibodies against a SARS-CoV-2 peptide

Authors: Emily Engelhart, Ryan Emerson, Leslie Shing, Chelsea Lennartz, Daniel Guion, Mary Kelley, Charles Lin, Randolph Lopez, David Younger, Matthew E Walsh

Journal: Sci Data

PubMed ID: 36289234

Doi: 10.1038/s41597-022-01779-4

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ICG-Dimeric Her2-Specific Affibody Conjugates for Tumor Imaging and Photothermal Therapy for Her2-Positive Tumors

Authors: Dianlong Jia, Huimin Liu, Shuhui Zheng, Dandan Yuan, Ruohan Sun, Fei Wang, Yang Li, Hui Li, Fengjiao Yuan, Qing Fan, Zhenxiong Zhao

Journal: Mol Pharm

PubMed ID: 36315025

Doi: 10.1021/acs.molpharmaceut.2c00708

Products & Services: Bacterial Expression

Autophagic flux restoration enhances the antitumor efficacy of tumor infiltrating lymphocytes

Authors: Chaoting Zhang, Yizhe Sun, Shance Li, Luyan Shen, Xia Teng, Yefei Xiao, Nan Wu, Zheming Lu

Journal: J Immunother Cancer

PubMed ID: 36307150

Doi: 10.1136/jitc-2022-004868

Products & Services: Plasmid DNA Preparation

A method for targeting a specified segment of DNA to a bacterial microorganelle

Authors: Jan Otoničar, Maja Hostnik, Maja Grundner, Rok Kostanjšek, Tajda Gredar, Maja Garvas, Zoran Arsov, Zdravko Podlesek, Cene Gostinčar, Jernej Jakše, Stephen J W Busby, Matej Butala

Journal: Nucleic Acids Res

PubMed ID: 36029110

Doi: 10.1093/nar/gkac714

Products & Services: Proteins, Expression, Isolation and Analysis

Macromolecular crowding amplifies allosteric regulation of T-Cell Protein Tyrosine Phosphatase

Authors: May Thwe Tun, Shen Yang, Fabio Luis Forti, Eugenio Santelli, Nunzio Bottini

Journal: J Biol Chem

PubMed ID: 36328244

Doi: 10.1016/j.jbc.2022.102655

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Inhibition of Glypican-3 Cleavage Results in Reduced Cell Proliferation in a Liver Cancer Cell Line

Authors: Emily J Schepers, Charissa Lake, Kathryn Glaser, Alexander J Bondoc

Journal: J Surg Res

PubMed ID: 36272230

Doi: 10.1016/j.jss.2022.09.011

Products & Services: GenParts™ DNA Fragments

A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers

Authors: Rongjie Cheng, Fanying Li, Maolei Zhang, Xin Xia, Jianzhuang Wu, Xinya Gao, Huangkai Zhou, Zhi Zhang, Nunu Huang, Xuesong Yang, Yaliang Zhang, Shunli Shen, Tiebang Kang, Zexian Liu, Feizhe Xiao, Hongwei Yao, Jianbo Xu, Chao Yan, Nu Zhang

Journal: Cell Res

PubMed ID: 36241718

Doi: 10.1038/s41422-022-00726-7

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Upregulation of programmed cell death 1 by interferon gamma and its biological functions in human monocytes

Authors: Kittitach Sri-Ngern-Ngam, Pornlapat Keawvilai, Trairak Pisitkun, Tanapat Palaga

Journal: Biochem Biophys Rep

PubMed ID: 36275930

Doi: 10.1016/j.bbrep.2022.101369

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Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage

Authors: Qianying Lv, Xinli Han, Jiajia Ni, Qianqian Ma, Rufeng Dai, Jiaojiao Liu, Jialu Liu, Yihui Zhai, Qian Shen, Li Sun, Haimei Liu, Jia Rao, Hong Xu

Journal: Cell Death Dis

PubMed ID: 36229446

Doi: 10.1038/s41419-022-05313-7

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DNA damage-induced nuclear import of HSP90α is promoted by Aha1

Authors: Nupur Fangaria, Khushboo Rani, Priyanka Singh, Sandeep Dey, Kota Arun Kumar, Sunanda Bhattacharyya

Journal: Mol Biol Cell

PubMed ID: 36260391

Doi: 10.1091/mbc.E21-11-0554

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A broadly protective vaccine against cutaneous human papillomaviruses

Authors: Filipe Colaco Mariz, Kathrin Balz, Manuela Dittrich, Yueru Zhang, Fan Yang, Xueer Zhao, Angelo Bolchi, Simone Ottonello, Martin Müller

Journal: npj Vaccines

PubMed ID: 36216845

Doi: 10.1038/s41541-022-00539-0

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An inducible gene from glycoside hydrolase one family of decreases larval survival when feeding on host plant

Authors: Wei Chen, Yuhong Dong, Ling Zheng, Yingfang Lai, Feifei Li, Li Zhou, Beibei Wang, Minsheng You, Weiyi He

Journal: Front Physiol

PubMed ID: 36338470

Doi: 10.3389/fphys.2022.1013092

Products & Services: Recombinant Antibody Expression

Combating the SARS-CoV-2 Omicron (BA1) and BA2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies

Authors: Yingdan Wang, Xiang Zhang, Yunping Ma, Yanqun Wang, Wuqiang Zhan, Qinwen Zheng, Meng Zhang, Ping Ji, Mei Liu, Qianying Liu, Tingting Sun, Tongyu Zhu, Yumei Wen, Lei Sun, Jincun Zhao, Fan Wu, Zhenguo Chen, Jinghe Huang

Journal: Cell Discov

PubMed ID: 36207299

Doi: 10.1038/s41421-022-00463-6

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An arrayed genome-wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate-limiting for prion propagation

Authors: Merve Avar, Daniel Heinzer, Alana M Thackray, Yingjun Liu, Marian Hruska-Plochan, Stefano Sellitto, Elke Schaper, Daniel P Pease, Jiang-An Yin, Asvin Kk Lakkaraju, Marc Emmenegger, Marco Losa, Andra Chincisan, Simone Hornemann, Magdalini Polymenidou, Raymond Bujdoso, Adriano Aguzzi

Journal: EMBO J

PubMed ID: 36254605

Doi: 10.15252/embj.2022112338

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Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses

Authors: Janice Zhirong Jia, Chee Wah Tan, Samuel M S Cheng, Haogao Gu, Aileen Ying Yan Yeoh, Chris Ka Pun Mok, Yanqun Wang, Jincun Zhao, Nancy H L Leung, Benjamin J Cowling, Leo L M Poon, David S C Hui, Linfa Wang, Malik Peiris, Sophie A Valkenburg

Journal: Nat Commun

PubMed ID: 36271047

Doi: 10.1038/s41467-022-34038-6

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On the role of cell surface associated, mucin-like glycoproteins in the pennate diatom Craspedostauros australis (Bacillariophyceae)

Authors: Nicole Poulsen, Helene Hennig, Veikko F Geyer, Stefan Diez, Richard Wetherbee, Sorel Fitz-Gibbon, Matteo Pellegrini, Nils Kröger

Journal: J Phycol

PubMed ID: 36199194

Doi: 10.1111/jpy.13287

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Transient State Kinetics of Apicoplast DNA Polymerase Suggests the Involvement of Accessory Factors for Efficient and Accurate DNA Synthesis

Authors: Anamika Kumari, Anjali Yadav, Indrajit Lahiri

Journal: Biochemistry

PubMed ID: 36251801

Doi: 10.1021/acs.biochem.2c00446

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