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Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant

Authors: Wei Zhang, Ke Shi, Qibin Geng, Gang Ye, Hideki Aihara, Fang Li

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36256797

Doi: 10.1073/pnas.2206509119

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Structural basis for product specificities of MLL family methyltransferases

Authors: Yanjing Li , Lijie Zhao , Yuebin Zhang , Ping Wu , Ying Xu , Jun Mencius , Yongxin Zheng , Xiaoman Wang , Wancheng Xu , Naizhe Huang , Xianwen Ye , Ming Lei , Pan Shi , Changlin Tian , Chao Peng , Guohui Li , Zhijun Liu , Shu Quan , Yong Chen

Journal: Mol Cell

PubMed ID: 36108631

Doi: 10.1016/j.molcel.2022.08.022

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Advanced pathway engineering for phototrophic putrescine production

Authors: Robert A Freudenberg , Luisa Wittemeier , Alexander Einhaus , Thomas Baier , Olaf Kruse

Journal: Plant Biotechnol J

PubMed ID: 35748533

Doi: 10.1111/pbi.13879

Products & Services: Gene Synthesis

Human melanocortin-2 receptor: Identifying a role for residues in the TM4, EC2, and TM5 domains in activation and trafficking as a result of co-expression with the accessory protein, Mrap1 in Chinese Hamster Ovary Cells.

Authors: Perry V Davis , Ciaran A Shaughnessy , Robert M Dores

Journal: Biomolecules

PubMed ID: 36291631

Doi: 10.3390/biom12101422

Products & Services: Gene Synthesis

Labeling Ebola Virus with a Self-Splicing Fluorescent Reporter

Authors: Baylee Heiden , Elke Mühlberger , Christopher W Lennon , Adam J Hume

Journal: Microorganisms

PubMed ID: 36363701

Doi: 10.3390/microorganisms10112110

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Crystal structure of an L-type lectin domain from archaea

Authors: Farha Khan, Kaza Suguna

Journal: Proteins

PubMed ID: 36301308

Doi: 10.1002/prot.26440

Products & Services: PCR Cloning and Subcloning

Authors: Eyby Leon, Claris Nde, Randall S Ray, Diego Preciado, Irene E Zohn

Journal: Am J Med Genet A

PubMed ID: 36263470

Doi: 10.1002/ajmg.a.62991

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Divergent SARS-CoV-2-specific T cell responses in intensive care unit workers following mRNA COVID-19 vaccination

Authors: Estefanía Salgado Del Riego, María Laura Saiz, Viviana Corte-Iglesias, Blanca Leoz Gordillo, Cristina Martin-Martin, Mercedes Rodríguez-Pérez, Dolores Escudero, Carlos Lopez-Larrea, Beatriz Suarez-Alvarez

Journal: Front Immunol

PubMed ID: 36275696

Doi: 10.3389/fimmu.2022.942192

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Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

Authors: Phillip Pymm, Samuel J Redmond, Olan Dolezal, Francesca Mordant, Ester Lopez, James P Cooney, Kathryn C Davidson, Ebene R Haycroft, Chee Wah Tan, Rebecca Seneviratna, Samantha L Grimley, Damian F J Purcell, Stephen J Kent, Adam K Wheatley, Lin-Fa Wang, Andrew Leis, Alisa Glukhova, Marc Pellegrini, Amy W Chung, Kanta Subbarao, Adam P Uldrich, Wai-Hong Tham, Dale I Godfrey, Nicholas A Gherardin

Journal: iScience

PubMed ID: 36213007

Doi: 10.1016/j.isci.2022.105259

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 Transmission from Human to Pet and Suspected Transmission from Pet to Human, Thailand

Authors: Chutchai Piewbang, Panida Poonsin, Pattiya Lohavicharn, Sabrina Wahyu Wardhani, Wichan Dankaona, Jiratchaya Puenpa, Yong Poovorawan, Somporn Techangamsuwan

Journal: J Clin Microbiol

PubMed ID: 36314788

Doi: 10.1128/jcm.01058-22

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Antibody Response to Rotavirus C Pre-Farrow Natural Planned Exposure to Gilts and Their Piglets

Authors: Deepak Kumar, Amanda V Anderson, Jeremy Pittman, Nora L Springer, Douglas G Marthaler, Waithaka Mwangi

Journal: Viruses

PubMed ID: 36298806

Doi: 10.3390/v14102250

Products & Services: Mammalian Expression

The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation

Authors: Tsung-Chuan Ho, Nai-Wen Fan, Shu-I Yeh, Show-Li Chen, Yeou-Ping Tsao

Journal: Transl Vis Sci Technol

PubMed ID: 36201200

Doi: 10.1167/tvst.11.10.12

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Deciphering the Key Regulatory Roles of KLF6 and Bta-miR-148a on Milk Fat Metabolism in Bovine Mammary Epithelial Cells

Authors: Ambreen Iqbal, Haibin Yu, Ping Jiang, Zhihui Zhao

Journal: Genes (Basel)

PubMed ID: 36292712

Doi: 10.3390/genes13101828

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Focused B cell response to recurring gluten motif with implications for epitope spreading in celiac disease

Authors: Chunyan Zhou, Thomas Østerbye, Emil Bach, Shiva Dahal-Koirala, Lene S Høydahl, Øyvind Steinsbø, Jørgen Jahnsen, Knut E A Lundin, Søren Buus, Ludvig M Sollid, Rasmus Iversen

Journal: Cell Rep

PubMed ID: 36288703

Doi: 10.1016/j.celrep.2022.111541

Products & Services: Recombinant Antibody Expression

Investigating the Role of African Horse Sickness Virus VP7 Protein Crystalline Particles on Virus Replication and Release

Authors: Shani Bekker, Christiaan A Potgieter, Vida van Staden, Jacques Theron

Journal: Viruses

PubMed ID: 36298748

Doi: 10.3390/v14102193

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Single-cell RNA sequencing analysis of shrimp immune cells identifies macrophage-like phagocytes

Authors: Peng Yang , Yaohui Chen , Zhiqi Huang , Huidan Xia , Ling Cheng , Hao Wu , Yueling Zhang , Fan Wang

Journal: Elife

PubMed ID: 36200862

Doi: 10.7554/eLife.80127

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Intracellular infection by symbiotic bacteria requires the mitotic kinase AURORA1

Authors: Jin-Peng Gao , Suyu Jiang , Yangyang Su , Ping Xu , Junjie Wang , Wenjie Liang , Cheng-Wu Liu , Jeremy D Murray

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36252014

Doi: doi.org/10.1073/pnas.2202606119

Products & Services: Gene Synthesis

Observation of conformational changes that underlie the catalytic cycle of Xrn2

Authors: Jan H Overbeck, David Stelzig, Anna-Lisa Fuchs, Jan Philip Wurm, Remco Sprangers

Journal: Nature Chemical Biology

PubMed ID: 36008487

Doi: 10.1038/s41589-022-01111-6

Products & Services: Codon Optimization Gene Synthesis

Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair

Authors: Oguz Bolgi, Maria Silva-Garcia, Breyan Ross, Esther Pilla, Vijayalakshmi Kari, Markus Killisch, Melanie Spitzner, Nadine Stark, Christof Lenz, Konstantin Weiss, Laura Donzelli, Mark D Gorrell, Marian Grade, Jan Riemer, Henning Urlaub, Matthias Dobbelstein, Robert Huber, Ruth Geiss-Friedlander

Journal: EMBO Reports

Doi: 10.15252/embr.202154136

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Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance

Authors: Jaël S Copier , Marianne Bootsma , Chai A Ng , Arthur A M Wilde , Robin A Bertels , Hennie Bikker , Imke Christiaans , Saskia N van der Crabben , Janna A Hol , Tamara T Koopmann , Jeroen Knijnenburg , Aafke A J Lommerse , Jasper J van der Smagt , Connie R Bezzina , Jamie I Vandenberg , Arie O Verkerk , Daniela Q C M Barge-Schaapveld , Elisabeth M Lodder

Journal: Hum Mol Genet

PubMed ID: 36269083

Doi: 10.1093/hmg/ddac261

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Metabolomic analysis of rapeseed priming with H2O2 in response to germination under chilling stress

Authors: Zhiwei Gu, Duan Wang, Qingtao Gong, Juan You, Qingji Ren, Haimei An, Yongyin Zhou, Haidong Jiang

Journal: Plant Growth Regulation

Doi: 10.1007/s10725-022-00918-6

Products & Services: Gene Synthesis

A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin

Authors: Qiyao Chai , Shanshan Yu, Yanzhao Zhong , Zhe Lu , Changgen Qiu, Yang Yu , Xinwen Zhang , Yong Zhang, Zehui Lei, Lihua Qiang, Bing-Xi Li, Yu Pang, Xiao-Bo Qiu, Jing Wang , Cui Hua Liu

Journal: Science .

PubMed ID: 36227980

Doi: 10.1126/science.abq0132

Products & Services: DNA Sequencing Peptide Synthesis

Correction to: Selection of DNA aptamer and its application as an electrical biosensor for Zika virus detection in human serum

Authors: Goeun Park, Myoungro Lee, Jiatong Kang, Chulwhan Park, Junhong Min, Taek Lee

Journal: Nano Converg

PubMed ID: 36315359

Doi: 10.1186/s40580-022-00340-8

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Available online 28 June 2022 0925-4005/© 2022 Elsevier B.V. All rights reserved. A universal CRISPR/Cas12a-mediated AuNPs aggregation-based surface-enhanced Raman scattering (CRISPR/Cas-SERS) platform for virus gene detection

Authors: Ailing Su ， Yuan Liu , Xiumian Cao , Weiqing Xu , Chongyang Liang , Shuping Xu

Journal: Sensors and Actuators B: Chemical

Doi: 10.1016/j.snb.2022.132295

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Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein

Authors: Xiaodong Luan, Xinming Li, Yufan Li, Gengchen Su, Wanchao Yin, Yi Jiang, Ning Xu, Feng Wang, Wang Cheng, Ye Jin, Leike Zhang, H. Eric Xu, Yi Xue, Shuyang Zhang

Journal: Science Bulletin

Doi: 10.1016/j.scib.2022.10.021

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NAC Transcription Factor Improved Drought Stress Tolerance in Soybean

Authors: Chengfeng Yang, Yanzhong Huang, Peiyun Lv, Augustine Antwi-Boasiako, Naheeda Begum, Tuanjie Zhao, Jinming Zhao

Journal: Int J Mol Sci

PubMed ID: 36233329

Doi: 10.3390/ijms231912029

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Rescue of the first alphanucleorhabdovirus entirely from cloned complementary DNA: An efficient vector for systemic expression of foreign genes in maize and insect vectors

Authors: Surapathrudu Kanakala, César A D Xavier, Kathleen M Martin, Hong Hanh Tran, Margaret G Redinbaugh, Anna E Whitfield

Journal: Mol Plant Pathol

PubMed ID: 36239302

Doi: 10.1111/mpp.13273

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High-throughput genome editing in rice with a virus-based surrogate system

Authors: Yifu Tian, Dating Zhong, Xinbo Li, Rundong Shen, Han Han, Yuqin Dai, Qi Yao, Xuening Zhang, Qi Deng, Xuesong Cao, Jian-Kang Zhu, Yuming Lu

Journal: J Integr Plant Biol

PubMed ID: 36218268

Doi: 10.1111/jipb.13381

Products & Services: Proteins, Expression, Isolation and Analysis

Immunogenicity and reactogenicity of a third dose of BNT162b2 vaccine for COVID-19 after a primary regimen with BBIBP-CorV or BNT162b2 vaccines in Lima, Peru

Authors: Natalia Vargas-Herrera, Manuel Fernández-Navarro, Nestor E Cabezudo, Percy Soto-Becerra, Gilmer Solís-Sánchez, Stefan Escobar-Agreda, Javier Silva-Valencia, Luis Pampa-Espinoza, Ricardo Bado-Pérez, Lely Solari, Roger V Araujo-Castillo

Journal: PLoS ONE

PubMed ID: 36251630

Doi: 10.1371/journal.pone.0268419

Products & Services: Proteins, Expression, Isolation and Analysis

Lysyl-tRNA synthetase, a target for urgently needed M tuberculosis drugs

Authors: Simon R Green, Susan H Davis, Sebastian Damerow, Curtis A Engelhart, Michael Mathieson, Beatriz Baragaña, David A Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K Tamaki, Kirsteen I Buchanan, John Post, Karen Dowers, Sharon M Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C Kim, James M Bean, Navid Nahiyaan, Kyu Y Rhee, Qinglan Wang, Vee Y Tan, Helena I M Boshoff, Paul J Converse, Si-Yang Li, Yong S Chang, Nader Fotouhi, Anna M Upton, Eric L Nuermberger, Dirk Schnappinger, Kevin D Read, Lourdes Encinas, Robert H Bates, Paul G Wyatt, Laura A T Cleghorn

Journal: Nat Commun

PubMed ID: 36220877

Doi: 10.1038/s41467-022-33736-5

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Characterization of a GH5 endoxylanase from Penicillium funiculosum and its synergism with GH16 endo-1,3(4)-glucanase in saccharification of sugarcane bagasse

Authors: Olusola A Ogunyewo, Omoaruemike E Okereke, Sandeep Kumar, Syed Shams Yazdani

Journal: Sci Rep

PubMed ID: 36241677

Doi: 10.1038/s41598-022-21529-1

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Bioelectrocatalytic CO Reduction by Redox Polymer-Wired Carbon Monoxide Dehydrogenase Gas Diffusion Electrodes

Authors: Jana M Becker, Anna Lielpetere, Julian Szczesny, João R C Junqueira, Patricia Rodríguez-Maciá, James A Birrell, Felipe Conzuelo, Wolfgang Schuhmann

Journal: ACS Appl Mater Interfaces

PubMed ID: 36194638

Doi: 10.1021/acsami.2c09547

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Regulation of PaRBOH1-mediated ROS production in Norway spruce by Ca binding and phosphorylation

Authors: Kaloian Nickolov, Adrien Gauthier, Kenji Hashimoto, Teresa Laitinen, Enni Väisänen, Tanja Paasela, Rabah Soliymani, Takamitsu Kurusu, Kristiina Himanen, Olga Blokhina, Kurt V Fagerstedt, Soile Jokipii-Lukkari, Hannele Tuominen, Hely Häggman, Gunnar Wingsle, Teemu H Teeri, Kazuyuki Kuchitsu, Anna Kärkönen

Journal: Front Plant Sci

PubMed ID: 36311083

Doi: 10.3389/fpls.2022.978586

Products & Services: Proteins, Expression, Isolation and Analysis

Nitric Oxide Negatively Regulates the Rapid Formation of Primordia by Inhibiting the Mitochondrial Gene

Authors: Ludan Hou, Chenyang Huang, Xiangli Wu, Jinxia Zhang, Mengran Zhao

Journal: J Fungi (Basel)

PubMed ID: 36294620

Doi: 10.3390/jof8101055

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular architecture of the glycogen- committed PP1/PTG holoenzyme

Authors: Marta Stefania Semrau, Gabriele Giachin, Sonia Covaceuszach, Alberto Cassetta, Nicola Demitri, Paola Storici, Graziano Lolli

Journal: Nat Commun

PubMed ID: 36261419

Doi: 10.1038/s41467-022-33693-z

Products & Services: Mammalian Expression

Author Correction: [C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease

Authors: Tharick A Pascoal, Mira Chamoun, Elad Lax, Hsiao-Ying Wey, Monica Shin, Kok Pin Ng, Min Su Kang, Sulantha Mathotaarachchi, Andrea L Benedet, Joseph Therriault, Firoza Z Lussier, Frederick A Schroeder, Jonathan M DuBois, Baileigh G Hightower, Tonya M Gilbert, Nicole R Zürcher, Changning Wang, Robert Hopewell, Mallar Chakravarty, Melissa Savard, Emilie Thomas, Sara Mohaddes, Sarah Farzin, Alyssa Salaciak, Stephanie Tullo, A Claudio Cuello, Jean-Paul Soucy, Gassan Massarweh, Heungsun Hwang, Eliane Kobayashi, Bradley T Hyman, Bradford C Dickerson, Marie-Christine Guiot, Moshe Szyf, Serge Gauthier, Jacob M Hooker, Pedro Rosa-Neto

Journal: Nat Commun

PubMed ID: 36192402

Doi: 10.1038/s41467-022-33668-0

Products & Services: Proteins, Expression, Isolation and Analysis

SRC-3 deficiency prevents atherosclerosis development by decreasing endothelial ICAM-1 expression to attenuate macrophage recruitment

Authors: Wenbo Chen, Wuyang Zheng, Shixiao Liu, Qiang Su, Kangxi Ding, Ziguan Zhang, Ping Luo, Yong Zhang, Jianming Xu, Chundong Yu, Weihua Li, Zhengrong Huang

Journal: Int J Biol Sci

PubMed ID: 36263184

Doi: 10.7150/ijbs.74864

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Characterization of proteases from Irpex lacteus grown on minimally denatured soybean meals

Authors: Xiaoxu Zhu, Yufei Hua, Xiangzhen Kong, Xingfei Li, Yeming Chen, Caimeng Zhang

Journal: J Sci Food Agric

PubMed ID: 36317244

Doi: 10.1002/jsfa.12301

Products & Services: Proteins, Expression, Isolation and Analysis

Crystal Structures of Epstein-Barr Virus Bcl-2 Homolog BHRF1 Bound to Bid and Puma BH3 Motif Peptides

Authors: Chathura D Suraweera, Mark G Hinds, Marc Kvansakul

Journal: Viruses

PubMed ID: 36298777

Doi: 10.3390/v14102222

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Greater Phosphorylation of AMPK and Multiple AMPK Substrates in the Skeletal Muscle of 24 Month-old Calorie Restricted Compared to Ad Libitum Fed Male Rats

Authors: Amy Zheng, Seong Eun Kwak, Jesper B Birk, Edward B Arias, Dominic Thorley, Jørgen F P Wojtaszewski, Gregory D Cartee

Journal: J Gerontol A Biol Sci Med Sci

PubMed ID: 36269629

Doi: 10.1093/gerona/glac218

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Microsomal triglyceride transfer protein regulates intracellular lipolysis in adipocytes independent of its lipid transfer activity

Authors: Sujith Rajan, Peter Hofer, Amanda Christiano, Matthew Stevenson, Louis Ragolia, Eugenia Villa-Cuesta, Susan K Fried, Raymond Lau, Collin Braithwaite, Rudolf Zechner, Gary J Schwartz, M Mahmood Hussain

Journal: Metabolism

PubMed ID: 36228741

Doi: 10.1016/j.metabol.2022.155331

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COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

Authors: Giorgia Benegiamo, Maroun Bou Sleiman, Martin Wohlwend, Sandra Rodríguez-López, Ludger J E Goeminne, Pirkka-Pekka Laurila, Marie Klevjer, Minna K Salonen, Jari Lahti, Pooja Jha, Sara Cogliati, José Antonio Enriquez, Ben M Brumpton, Anja Bye, Johan G Eriksson, Johan Auwerx

Journal: Nat Metab

PubMed ID: 36253618

Doi: 10.1038/s42255-022-00655-0

Products & Services: Mammalian Expression

Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack

Authors: Shuang Yang, Giorgos Hiotis, Yi Wang, Junjian Chen, Jia-Huai Wang, Mikyung Kim, Ellis L Reinherz, Thomas Walz

Journal: Nat Commun

PubMed ID: 36302771

Doi: 10.1038/s41467-022-34008-y

Products & Services: Proteins, Expression, Isolation and Analysis

N-Acylethanolamine acid amidase (NAAA) exacerbates psoriasis inflammation by enhancing dendritic cell (DCs) maturation

Authors: Yuhang Li, Yitian Li, Sennan Xu, Yue Chen, Pan Zhou, Ting Hu, Hua Li, Ying Liu, Yaping Xu, Jie Ren, Yan Qiu, Canzhong Lu

Journal: Pharmacol Res

PubMed ID: 36244543

Doi: 10.1016/j.phrs.2022.106491

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Achieving regioselective materials binding using multidomain peptides

Authors: Ruitao Jin, Nermina Brljak, Robert Sangrigoli, Tiffany R Walsh, Marc R Knecht

Journal: Nanoscale

PubMed ID: 36073151

Doi: 10.1039/d2nr03169h

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Genetic variation in gene linked to predisposition of T2DM: A case control study

Authors: Archna Bhargave, Kiran Devi, Imteyaz Ahmad, Anita Yadav, Ranjan Gupta

Journal: J Diabetes Metab Disord

PubMed ID: 36249912

Doi: 10.1007/s40200-022-01131-y

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Supramolecular Assembly and Small-Molecule Binding by Protein-Engineered Coiled-Coil Fibers

Authors: Dustin Britton, Julia Monkovic, Sihan Jia, Chengliang Liu, Farbod Mahmoudinobar, Michael Meleties, P Douglas Renfrew, Richard Bonneau, Jin Kim Montclare

Journal: Biomacromolecules

PubMed ID: 36227640

Doi: 10.1021/acs.biomac.2c01031

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The PSI Domain of the MET Oncogene Encodes a Functional Disulfide Isomerase Essential for the Maturation of the Receptor Precursor

Authors: Dogus Murat Altintas, Simona Gallo, Cristina Basilico, Marina Cerqua, Alessio Bocedi, Annapia Vitacolonna, Orsola Botti, Elena Casanova, Ilaria Rancati, Chiara Milanese, Sara Notari, Giorgia Gambardella, Giorgio Ricci, Pier Giorgio Mastroberardino, Carla Boccaccio, Tiziana Crepaldi, Paolo Maria Comoglio

Journal: Int J Mol Sci

PubMed ID: 36293286

Doi: 10.3390/ijms232012427

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EP-Pred: A Machine Learning Tool for Bioprospecting Promiscuous Ester Hydrolases

Authors: Ruite Xiang, Laura Fernandez-Lopez, Ana Robles-Martín, Manuel Ferrer, Victor Guallar

Journal: Biomolecules

PubMed ID: 36291739

Doi: 10.3390/biom12101529

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Tannin Reduces the Incidence of Polyspermic Penetration in Porcine Oocytes

Authors: Jing-Tao Sun, Jia-Hui Liu, Xi-Qing Jiang, Xin Luo, Jin-Dong Yuan, Qi Zhang, Xin-Yue Qi, Sanghoon Lee, Zhong-Hua Liu, Jun-Xue Jin

Journal: Antioxidants (Basel)

PubMed ID: 36290750

Doi: 10.3390/antiox11102027

Products & Services: Proteins, Expression, Isolation and Analysis

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