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AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling

Authors: Renata Ferrarotto, Vasudha Mishra, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch, Adi Mondshine, Maria Motin, Tal Leibovich-Rivkin, Matti Davis, Joel Kaye, Christopher R Weber, Le Shen, Alexander T Pearson, Ari J Rosenberg, Xiangying Chen, Alka Singh, Jon C Aster, Nishant Agrawal, Evgeny Izumchenko

Journal: Cell Death Dis

PubMed ID: 35931701

Doi: 10.1038/s41419-022-05133-9

Products & Services: Mammalian Expression

Oral glucagon-like peptide 1 analogue ameliorates glucose intolerance in db/db mice

Authors: Hanlin Zhang, Meng Dong, Shouli Yuan, Wanzhu Jin

Journal: Biotechnol Lett

PubMed ID: 36006576

Doi: 10.1007/s10529-022-03288-1

Products & Services: Peptide Synthesis

A Localized Materials-Based Strategy to Non-Virally Deliver Chondroitinase ABC mRNA Improves Hindlimb Function in a Rat Spinal Cord Injury Model

Authors: Andrew S Khalil, Daniel Hellenbrand, Kaitlyn Reichl, Jennifer Umhoefer, Mallory Filipp, Joshua Choe, Amgad Hanna, William L Murphy

Journal: Adv Healthc Mater

PubMed ID: 35882512

Doi: 10.1002/adhm.202200206

Products & Services: Plasmid DNA Preparation

The NCF1 variant pR90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells

Authors: Yao Meng, Jianyang Ma, Chao Yao, Zhizhong Ye, Huihua Ding, Can Liu, Jun Li, Guanhua Li, Yuke He, Jia Li, Zhihua Yin, Li Wu, Haibo Zhou, Nan Shen

Journal: J Clin Invest

PubMed ID: 35788118

Doi: 10.1172/JCI153619

Products & Services: Proteins, Expression, Isolation and Analysis

Novel prime-boost immune-based therapy inhibiting both hepatitis B and D virus infections

Authors: Rani Burm, Panagiota Maravelia, Gustaf Ahlen, Sandra Ciesek, Noelia Caro Perez, Anna Pasetto, Stephan Urban, Freya Van Houtte, Lieven Verhoye, Heiner Wedemeyer, Magnus Johansson, Lars Frelin, Matti Sällberg, Philip Meuleman

Journal: Gut

PubMed ID: 35977815

Doi: 10.1136/gutjnl-2022-327216

Products & Services: Proteins, Expression, Isolation and Analysis

mmu-microRNA-92a-3p attenuates pulmonary fibrosis by modulating Cpeb4-mediated Smad2/3 signaling pathway

Authors: Mengkun Shi, Huixia Cui, Jialun Shi, Yunqing Mei

Journal: Funct Integr Genomics

PubMed ID: 35909199

Doi: 10.1007/s10142-022-00879-z

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Genome of Uncovers an Extensive Arsenal of Virulence-Related Genes among the Broad-Host-Range Necrotrophic Plant Pathogens

Authors: Paul Daly, Dongmei Zhou, Danyu Shen, Yifan Chen, Taiqiang Xue, Siqiao Chen, Qimeng Zhang, Jinfeng Zhang, Jamie McGowan, Feng Cai, Guan Pang, Nan Wang, Taha Majid Mahmood Sheikh, Sheng Deng, Jingjing Li, Hüseyin Okan Soykam, Irem Kara, David A Fitzpatrick, Irina S Druzhinina, Günseli Bayram Akcapinar, Lihui Wei

Journal: Microbiol Spectr

PubMed ID: 35946960

Doi: 10.1128/spectrum.02268-21

Products & Services: Proteins, Expression, Isolation and Analysis

Sall4 guides p53-mediated enhancer interference upon DNA damage in mouse embryonic stem cells

Authors: Lei Wang, Xiaojun Tan, Lu Chen, Sisi Xu, Weiping Huang, Nan Chen, Yizhou Wu, Chunyan Wang, Daqiang Zhou, Mangmang Li

Journal: Stem Cells

PubMed ID: 35977539

Doi: 10.1093/stmcls/sxac058

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Rotavirus Spike Protein VP4 Mediates Viroplasm Assembly by Association to Actin Filaments

Authors: Janine Vetter, Guido Papa, Michael Seyffert, Kapila Gunasekera, Giuditta De Lorenzo, Mahesa Wiesendanger, Jean-Louis Reymond, Cornel Fraefel, Oscar R Burrone, Catherine Eichwald

Journal: J Virol

PubMed ID: 35938869

Doi: 10.1128/jvi.01074-22

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A Pan-Pneumovirus vaccine based on immunodominant epitopes of the fusion protein

Authors: Jiachen Huang, Rose J Miller, Jarrod J Mousa

Journal: Front Immunol

PubMed ID: 36003370

Doi: 10.3389/fimmu.2022.941865

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Engineering cell morphology by CRISPR interference in Acinetobacter baylyi ADP1

Authors: Jin Luo, Elena Efimova, Daniel Christoph Volke, Ville Santala, Suvi Santala

Journal: Microb Biotechnol

PubMed ID: 36005297

Doi: 10.1111/1751-7915.14133

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An investigation across 45 languages and 12 language families reveals a universal language network

Authors: Saima Malik-Moraleda, Dima Ayyash, Jeanne Gallée, Josef Affourtit, Malte Hoffmann, Zachary Mineroff, Olessia Jouravlev, Evelina Fedorenko

Journal: Nat Neurosci

PubMed ID: 35856094

Doi: 10.1038/s41593-022-01114-5

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Structure of a nucleosome-bound MuvB transcription factor complex reveals DNA remodelling

Authors: Marios G Koliopoulos , Reyhan Muhammad , Theodoros I Roumeliotis , Fabienne Beuron , Jyoti S Choudhary , Claudio Alfieri

Journal: Nat Commun

PubMed ID: 36038598

Doi: 10.1038/s41467-022-32798-9

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A specific anti-IFITM2 antibody bars the way to SARS-CoV-2 entry into host cells.

Authors: Anna Basile , Carla Zannella , Margot De Marco , Gianluigi Franci , Massimiliano Galdiero , Giuseppina Sanna , Aldo Manzin , Massimiliano Chetta , Maria Caterina Turco , Alessandra Rosati , Liberato Marzullo

Journal: biorxiv

Doi: doi.org/10.1101/2022.08.04.502768

Products & Services: Monoclonal Antibody Services Recombinant Antibody Expression

Omicron BA4/BA5 escape neutralizing immunity elicited by BA1 infection

Authors: Khadija Khan, Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy, Sandile Cele, Gila Lustig, Daniel Amoako, Nicole Wolter, Natasha Samsunder, Aida Sivro, James Emmanuel San, Jennifer Giandhari, Houriiyah Tegally, Sureshnee Pillay, Yeshnee Naidoo, Matilda Mazibuko, Yoliswa Miya, Nokuthula Ngcobo, Nithendra Manickchund, Nombulelo Magula, Quarraisha Abdool Karim, Anne von Gottberg, Salim S Abdool Karim, Willem Hanekom, Bernadett I Gosnell, Richard J Lessells, Tulio de Oliveira, Mahomed-Yunus S Moosa, Alex Sigal

Journal: Nat Commun

PubMed ID: 35948557

Doi: 10.1038/s41467-022-32396-9

Products & Services: Monoclonal Antibody Services

Chemical shift assignments of calmodulin bound to a C-terminal site (residues 1120-1147) in the β-subunit of a retinal cyclic nucleotide-gated channel (CNGB1)

Authors: Aritra Bej, James B Ames

Journal: Biomol NMR Assign

PubMed ID: 35986879

Doi: 10.1007/s12104-022-10101-7

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Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies

Authors: Mauro Montalbano, Lajja Majmundar, Urmi Sengupta, Leiana Fung, Rakez Kayed

Journal: Brain Pathol

PubMed ID: 36054524

Doi: 10.1111/bpa.13112

Products & Services: Proteins, Expression, Isolation and Analysis

Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer's clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1

Authors: Olivia M S Carmo, Gerald J Shami, Dezerae Cox, Boyin Liu, Adam J Blanch, Snigdha Tiash, Leann Tilley, Matthew W A Dixon

Journal: PLoS Pathog

PubMed ID: 35930605

Doi: 10.1371/journal.ppat.1009882

Products & Services: Bacterial Expression

Design of Peptides for Membrane Insertion: The Critical Role of Charge Separation

Authors: Sydney C Povilaitis, Arman Fathizadeh, Molly Kogan, Ron Elber, Lauren J Webb

Journal: J Phys Chem B

PubMed ID: 35997537

Doi: 10.1021/acs.jpcb.2c04615

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Layer-by-Layer Delivery of Multiple Antigens Using Trimethyl Chitosan Nanoparticles as a Malaria Vaccine Candidate

Authors: Yang Xu, Ziyou Zhou, Brad Brooks, Tammy Ferguson, Judy Obliosca, Jing Huang, Izumi Kaneko, Shiroh Iwanaga, Masao Yuda, Yukiko Tsuji, Huitang Zhang, Christina C Luo, Xunqing Jiang, Xiang-Peng Kong, Moriya Tsuji, Christopher K Tison

Journal: Front Immunol

PubMed ID: 36059505

Doi: 10.3389/fimmu.2022.900080

Products & Services: Plasmid DNA Preparation

Evolution of transcriptional regulation of histidine metabolism in Gram-positive bacteria

Authors: German A Ashniev, Natalia V Sernova, Aleksei E Shevkoplias, Ivan D Rodionov, Irina A Rodionova, Alexey G Vitreschak, Mikhail S Gelfand, Dmitry A Rodionov

Journal: BMC Genomics

PubMed ID: 36008760

Doi: 10.1186/s12864-022-08796-y

Products & Services: Codon Optimization

Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer

Authors: Carmela Martini, Jessica M Logan, Alexandra Sorvina, Colin Gordon, Andrew R Beck, Ben S-Y Ung, Maria C Caruso, Courtney Moore, Ashleigh Hocking, Ian R D Johnson, Ka Lok Li, Litsa Karageorgos, Ashley M Hopkins, Adrian J Esterman, Chelsea Huzzell, Robert D Brooks, Joanna Lazniewska, Shane M Hickey, Christie Bader, Emma Parkinson-Lawrence, Roberto Weigert, Michael J Sorich, Prerna Tewari, Cara Martin, Sharon O'Toole, Mark Bates, Mark Ward, Bashir Mohammed, Helen Keegan, William Watson, Sophie Prendergast, Sheena Heffernan, Sarah NiMhaolcatha, Roisin O'Connor, Victoria Malone, Marguerite Carter, Katie Ryan, Nathan Brady, Andres Clarke, Filip Sokol, Sarita Prabhakaran, Jürgen Stahl, Sonja Klebe, Hemamali Samaratunga, Brett Delahunt, Stavros Selemidis, Kim L Moretti, Lisa M Butler, John J O'Leary, Douglas A Brooks

Journal: Pathology

PubMed ID: 36089417

Doi: 10.1016/j.pathol.2022.08.001

Products & Services: Monoclonal Antibody Services

Revisiting the multisite phosphorylation that produces the M-phase supershift of key mitotic regulators

Authors: Tan Tan, Chuanfen Wu, Boye Liu, Bih-Fang Pan, David H Hawke, Zehao Su, Shuaishuai Liu, Wei Zhang, Ruoning Wang, Sue-Hwa Lin, Jian Kuang

Journal: Mol Biol Cell

PubMed ID: 35976701

Doi: 10.1091/mbc.E22-04-0118

Products & Services: Proteins, Expression, Isolation and Analysis

A structure-based mechanism for displacement of the HEXIM adapter from 7SK small nuclear RNA

Authors: Vincent V Pham, Michael Gao, Jennifer L Meagher, Janet L Smith, Victoria M D'Souza

Journal: Commun Biol

PubMed ID: 35970937

Doi: 10.1038/s42003-022-03734-w

Products & Services: Plasmid DNA Preparation

Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth

Authors: Rossella Delle Donne, Rosa Iannucci, Laura Rinaldi, Luca Roberto, Maria A Oliva, Emanuela Senatore, Domenica Borzacchiello, Luca Lignitto, Giorgio Giurato, Francesca Rizzo, Assunta Sellitto, Francesco Chiuso, Salvatore Castaldo, Giovanni Scala, Virginia Campani, Valeria Nele, Giuseppe De Rosa, Chiara D'Ambrosio, Corrado Garbi, Andrea Scaloni, Alessandro Weisz, Concetta Ambrosino, Antonella Arcella, Antonio Feliciello

Journal: Commun Biol

PubMed ID: 35918402

Doi: 10.1038/s42003-022-03639-8

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Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy

Authors: Sobhika Agarwala, Keun-Young Kim, Sebastien Phan, Saeyeon Ju, Ye Eun Kong, Guillaume A Castillon, Eric A Bushong, Mark H Ellisman, Owen J Tamplin

Journal: Elife

PubMed ID: 35943143

Doi: 10.7554/eLife.64835

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Genetically Engineered Pigs as Efficient Salivary Gland Bioreactors for Production of Therapeutically Valuable Human Nerve Growth Factor

Authors: Fang Zeng, Sha Liao, Zhe Kuang, Qingchun Zhu, Hengxi Wei, Junsong Shi, Enqin Zheng, Zheng Xu, Sixiu Huang, Linjun Hong, Ting Gu, Jie Yang, Huaqiang Yang, Gengyuan Cai, Stefan Moisyadi, Johann Urschitz, Zicong Li, Zhenfang Wu

Journal: Cells

PubMed ID: 35954224

Doi: 10.3390/cells11152378

Products & Services: Plasmid DNA Preparation

Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer

Authors: Wuqiang Zhan, Xiaolong Tian, Xiang Zhang, Shenghui Xing, Wenping Song, Qianying Liu, Aihua Hao, Yuxia Hu, Meng Zhang, Tianlei Ying, Zhenguo Chen, Fei Lan, Lei Sun

Journal: J Virol

PubMed ID: 35924918

Doi: 10.1128/jvi.00480-22

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Screening of six cation exchange resins for high binding capacity, monomer purity and step yield: A case study

Authors: Wenwen Lu, Zhenzhen Zhang, Shengwei Zhang, Ting Zhang, Yan Wan, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 35970491

Doi: 10.1016/j.pep.2022.106155

Products & Services: Proteins, Expression, Isolation and Analysis

IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues

Authors: Anissa A Widjaja, Sonia Chothani, Sivakumar Viswanathan, Joyce Wei Ting Goh, Wei-Wen Lim, Stuart A Cook

Journal: Int J Mol Sci

PubMed ID: 36012165

Doi: 10.3390/ijms23168900

Products & Services: Mammalian Expression

In the footsteps of sea stars: deciphering the catalogue of proteins involved in underwater temporary adhesion

Authors: Morgane Algrain, Elise Hennebert, Philip Bertemes, Ruddy Wattiez, Patrick Flammang, Birgit Lengerer

Journal: Open Biol

PubMed ID: 35975651

Doi: 10.1098/rsob.220103

Products & Services: Proteins, Expression, Isolation and Analysis

Neuroimmune Responses in a New Experimental Animal Model of Cerebral Aspergillosis

Authors: Brianne N Sullivan, Mia A Baggett, Christa Guillory, MaryJane Jones, Chad Steele

Journal: MBio

PubMed ID: 36040029

Doi: 10.1128/mbio.02254-22

Products & Services: GenParts™ DNA Fragments

Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

Authors: Celia Martín-Otal, Aritz Lasarte-Cia, Diego Serrano, Noelia Casares, Enrique Conde, Flor Navarro, Inés Sánchez-Moreno, Marta Gorraiz, Patricia Sarrión, Alfonso Calvo, Carlos E De Andrea, José Echeveste, Amaia Vilas, Juan Roberto Rodriguez-Madoz, Jesús San Miguel, Felipe Prosper, Sandra Hervas-Stubbs, Juan Jose Lasarte, Teresa Lozano

Journal: J Immunother Cancer

PubMed ID: 35918123

Doi: 10.1136/jitc-2021-004479

Products & Services: Plasmid DNA Preparation

Identification and characterization of a novel peptide from rainbow trout (Oncorhynchus mykiss) with antimicrobial activity against Streptococcus iniae

Authors: Joseph F A Varga, Sascha R Brunner, Grant Cheng, Daniel Min, Marc G Aucoin, Andrew C Doxey, Brian Dixon

Journal: Dev Comp Immunol

PubMed ID: 36044968

Doi: 10.1016/j.dci.2022.104518

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Rapid Point-of-Care Test Kit for Bacterial Vaginosis: Detection of Vaginolysin and Clue Cells Using Paper Strips and a Smartphone

Authors: Devon C Pawley, Emre Dikici, Sapna K Deo, Patricia Raccamarich, Margaret A Fischl, Maria Alcaide, Sylvia Daunert

Journal: Anal Chem

PubMed ID: 35943181

Doi: 10.1021/acs.analchem.2c02094

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Immunogenicity and Safety of SARS-CoV-2 mRNA Vaccines in a Cohort of Patients With Type 1 Diabetes

Authors: Francesca D'Addio, Gianmarco Sabiu, Vera Usuelli, Emma Assi, Ahmed Abdelsalam, Anna Maestroni, Andy Joe Seelam, Moufida Ben Nasr, Cristian Loretelli, Davide Mileto, Giada Rossi, Ida Pastore, Laura Montefusco, Paola S Morpurgo, Laura Plebani, Antonio Rossi, Enrica Chebat, Andrea M Bolla, Maria Elena Lunati, Chiara Mameli, Maddalena Macedoni, Spinello Antinori, Stefano Rusconi, Maurizio Gallieni, Cesare Berra, Franco Folli, Massimo Galli, Maria Rita Gismondo, Gianvincenzo Zuccotti, Paolo Fiorina

Journal: Diabetes

PubMed ID: 35551366

Doi: 10.2337/db22-0053

Products & Services: Catalog Peptides

A partnership between the lipid scramblase XK and the lipid transfer protein VPS13A at the plasma membrane

Authors: Andrés Guillén-Samander, Yumei Wu, S Sebastian Pineda, Francisco J García, Julia N Eisen, Marianna Leonzino, Berrak Ugur, Manolis Kellis, Myriam Heiman, Pietro De Camilli

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35994651

Doi: 10.1073/pnas.2205425119

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Self-Assembly of Porcine Parvovirus Virus-like Particles and Their Application in Serological Assay

Authors: Yanfei Gao, Haiwei Wang, Shanghui Wang, Mingxia Sun, Zheng Fang, Xinran Liu, Xuehui Cai, Yabin Tu

Journal: Viruses

PubMed ID: 36016450

Doi: 10.3390/v14081828

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SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells

Authors: Shreyasi Mukherjee, David M Luedeke, Leslie McCoy, Makiko Iwafuchi, Aaron M Zorn

Journal: Cell Rep

PubMed ID: 36001974

Doi: 10.1016/j.celrep.2022.111247

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Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors

Authors: Sanghyun P Kim, Nolan R Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C Deniger, Frank J Lowery, Maria R Parkhurst, Lien T Ngo, Satyajit Ray, Yong F Li, Victoria Hill, Maria Florentin, Robert V Masi, Biman C Paria, Noam Levin, Alakesh Bera, Elizabeth A Hedges, Agnes Choi, Praveen D Chatani, Anup Y Parikh, Shoshana Levi, Samantha Seitter, Yong-Chen Lu, Zhili Zheng, Todd D Prickett, Li Jia, Jonathan M Hernandez, Chuong D Hoang, Paul F Robbins, Stephanie L Goff, Richard M Sherry, James C Yang, Steven A Rosenberg

Journal: Cancer Immunol Res

PubMed ID: 35749374

Doi: 10.1158/2326-6066.CIR-22-0040

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Optimized production and fluorescent labeling of SARS-CoV-2 virus-like particles

Authors: Manon Gourdelier, Jitendriya Swain, Coline Arone, Anita Mouttou, David Bracquemond, Peggy Merida, Saveez Saffarian, Sébastien Lyonnais, Cyril Favard, Delphine Muriaux

Journal: Sci Rep

PubMed ID: 36030323

Doi: 10.1038/s41598-022-18681-z

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Evolutionary adaptation of the protein folding pathway for secretability

Authors: Dries Smets, Alexandra Tsirigotaki, Jochem H Smit, Srinath Krishnamurthy, Athina G Portaliou, Anastassia Vorobieva, Wim Vranken, Spyridoula Karamanou, Anastassios Economou

Journal: EMBO J

PubMed ID: 36031863

Doi: 10.15252/embj.2022111344

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Disruption of nuclear envelope integrity as a possible initiating event in tauopathies

Authors: Marine Prissette, Wen Fury, Matthew Koss, Claudia Racioppi, Daria Fedorova, Ella Dragileva, Georgia Clarke, Taylor Pohl, John Dugan, Diana Ahrens, Joyce Chiu, Charleen Hunt, Chia-Jen Siao, Tara Young, Arijit Bhowmick, Vitaliy Rogulin, Mathieu Desclaux, Eric Y Hayden, Michael Podgorski, Min Gao, Lynn E Macdonald, David Frendewey, George D Yancopoulos, Brian Zambrowicz

Journal: Cell Rep

PubMed ID: 36001963

Doi: 10.1016/j.celrep.2022.111249

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Microporous affinity membranes and their incorporation into microfluidic devices for monitoring of therapeutic antibodies

Authors: Joshua D Berwanger, Melinda A Lake, Sanniv Ganguly, Junyan Yang, Christopher J Welch, Jacqueline C Linnes, Merlin Bruening

Journal: Talanta

PubMed ID: 36030739

Doi: 10.1016/j.talanta.2022.123842

Products & Services: Proteins, Expression, Isolation and Analysis

Dual Targeting Factors Are Required for LXG Toxin Export by the Bacterial Type VIIb Secretion System

Authors: Timothy A Klein, Dirk W Grebenc, Prakhar Y Shah, Owen D McArthur, Brandon H Dickson, Michael G Surette, Youngchang Kim, John C Whitney

Journal: MBio

PubMed ID: 36036513

Doi: 10.1128/mbio.02137-22

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USP29 Deubiquitinates SETD8 and Regulates DNA Damage-Induced H4K20 Monomethylation and 53BP1 Focus Formation

Authors: Yeray Hernández-Reyes, María Cristina Paz-Cabrera, Raimundo Freire, Veronique A J Smits

Journal: Cells

PubMed ID: 36010569

Doi: 10.3390/cells11162492

Products & Services: Proteins, Expression, Isolation and Analysis

Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency

Authors: Zhipeng Ai, Xinyu Xiang, Yangquan Xiang, Iwona Szczerbinska, Yuli Qian, Xiao Xu, Chenyang Ma, Yaqi Su, Bing Gao, Hao Shen, Muhammad Nadzim Bin Ramli, Di Chen, Yue Liu, Jia-Jie Hao, Huck Hui Ng, Dan Zhang, Yun-Shen Chan, Wanlu Liu, Hongqing Liang

Journal: Cell Rep

PubMed ID: 36001968

Doi: 10.1016/j.celrep.2022.111240

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Case report: A novel loss-of-function pathogenic variant in the KCNA1 cytoplasmic N-terminus causing carbamazepine-responsive type 1 episodic ataxia

Authors: Rían W Manville, Richard Sidlow, Geoffrey W Abbott

Journal: Front Neurol

PubMed ID: 36016548

Doi: 10.3389/fneur.2022.975849

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LIMP2 gene, evolutionarily conserved regulation by TFE3, relieves lysosomal stress induced by cholesterol

Authors: Hanze Guo, Yingying Zhu, Jiarui Li, Qipeng Zhang, Yan Chi

Journal: Life Sci

PubMed ID: 35987341

Doi: 10.1016/j.lfs.2022.120888

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Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase

Authors: Samantha N Muellers, Mattias M Nyitray, Nicholas Reynarowych, Edina Saljanin, Annie Laurie Benzie, Alan R Schoenfeld, Brian J Stockman, Karen N Allen

Journal: Biochemistry

PubMed ID: 35994320

Doi: 10.1021/acs.biochem.2c00361

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