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页码: 92/1026 每页显示数量
Developmental dynamics of RNA translation in the human brain
Authors: Erin E Duffy, Benjamin Finander, GiHun Choi, Ava C Carter, Iva Pritisanac, Aqsa Alam, Victor Luria, Amir Karger, William Phu, Maxwell A Sherman, Elena G Assad, Naomi Pajarillo, Alexandra Khitun, Elizabeth E Crouch, Sanika Ganesh, Jin Chen, Bonnie Berger, Nenad Sestan, Anne O'Donnell-Luria, Eric J Huang, Eric C Griffith, Julie D Forman-Kay, Alan M Moses, Brian T Kalish, Michael E Greenberg
Journal: Nat Neurosci
PubMed ID: 36171426
Doi: 10.1038/s41593-022-01164-9
Products & Services: DNA Sequencing   
Functional characterization of putative ecdysone transporters in lepidopteran pests
Authors: George-Rafael Samantsidis, Melina Fotiadou, Savvas Tzavellas, Sven Geibel, Ralf Nauen, Luc Swevers, Shane Denecke, John Vontas
Journal: Insect Biochem Mol Biol
PubMed ID: 36064128
Doi: 10.1016/j.ibmb.2022.103830
Products & Services: Plasmid DNA Preparation   
Atomic force microscopy measurements and model of DNA bending caused by binding of AraC protein
Authors: Mary Lowe, Benjamin Glezer, Brendan Toulan, Brian Hess
Journal: J Mol Recognit
PubMed ID: 36112092
Doi: 10.1002/jmr.2993
PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells
Authors: Yan Feng, Xu Zhang, Songfa Zhang, Shanshan Xu, Xiaojing Chen, Caiyun Zhou, Yongmei Xi, Xing Xie, Weiguo Lu
Journal: Front Biosci (Landmark Ed)
PubMed ID: 36224008
Doi: 10.31083/j.fbl2709262
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A bHLH transcription factor, SlbHLH96, promotes drought tolerance in tomato
Authors: Yunfei Liang , Fang Ma , Boyu Li , Cong Guo , Tixu Hu , Mingke Zhang , Yan Liang , Jianhua Zhu , Xiangqiang Zhan
Journal: Hortic Res
PubMed ID: 36467272
Doi: 10.1093/hr/uhac198
GPBAR1 preserves neurite and synapse of dopaminergic neurons via RAD21-OPCML signaling: Role in preventing Parkinson's disease in mouse model and human patients
Authors: Yajie Zhang, Xin Sun, Youjiao Zhang, Zhengwei Kang, Lei Cai, Jianhua Ding, Ming Lu, Gang Hu
Journal: Pharmacol Res
PubMed ID: 36152741
Doi: 10.1016/j.phrs.2022.106459
Products & Services: Custom DNA/RNA Oligos   
C3- and C3/C5-Epimerases Required for the Biosynthesis of the Capsular Polysaccharides from
Authors: Manas K Ghosh, Dao Feng Xiang, James B Thoden, Hazel M Holden, Frank M Raushel
Journal: Biochemistry
PubMed ID: 36093987
Doi: 10.1021/acs.biochem.2c00364
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terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic β-cells
Authors: Joshua A Nord, Sarah L Wynia-Smith, Alyssa L Gehant, Rachel A Jones Lipinski, Aaron Naatz, Inmaculada Rioja, Rab K Prinjha, John A Corbett, Brian C Smith
Journal: Front Endocrinol (Lausanne)
PubMed ID: 36176467
Doi: 10.3389/fendo.2022.923925
Products & Services: Plasmid DNA Preparation   
Utilization of Receptor-Binding Domain of SARS-CoV-2 Spike Protein Expressed in Escherichia coli for the Development of Neutralizing Antibody Assay
Authors: Termsak Tantiwiwat, Apisitt Thaiprayoon, Ake-Kavitch Siriatcharanon, Chakrit Tachaapaikoon, Nongluk Plongthongkum, Dujduan Waraho-Zhmayev
Journal: Mol Biotechnol
PubMed ID: 36103078
Doi: 10.1007/s12033-022-00563-4
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Complementary crosstalk between palmitoylation and phosphorylation events in MTIP regulates its role during invasion
Authors: Zille Anam, Geeta Kumari, Soumyadeep Mukherjee, Devasahayam Arokia Balaya Rex, Shreeja Biswas, Preeti Maurya, Susendaran Ravikumar, Nutan Gupta, Akhilesh Kumar Kushawaha, Raj Kumar Sah, Ayushi Chaurasiya, Jhalak Singhal, Niharika Singh, Shikha Kaushik, T S Keshava Prasad, Soumya Pati, Anand Ranganathan, Shailja Singh
Journal: Front Cell Infect Microbiol
PubMed ID: 36250062
Doi: 10.3389/fcimb.2022.924424
Products & Services: Recombinant Proteins   
Tag-Dependent Substrate Selection of ClpX Underlies Secondary Differentiation of Chlamydia trachomatis
Authors: Nicholas A Wood, Abigail R Swoboda, Amanda M Blocker, Derek J Fisher, Scot P Ouellette
Journal: MBio
PubMed ID: 36154190
Doi: 10.1128/mbio.01858-22
Ectopic expression of meiotic cohesin generates chromosome instability in cancer cell line
Authors: Abdelhalim Boukaba, Jian Liu, Carl Ward, Qiongfang Wu, Alexei Arnaoutov, Jierong Liang, Elena M Pugacheva, Mary Dasso, Victor Lobanenkov, Miguel Esteban, Alexander V Strunnikov
Journal: Proc Natl Acad Sci U S A
PubMed ID: 36179046
Doi: 10.1073/pnas.2204071119
Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
Authors: Kah Lok Chan, Juliana Gomez, Chelisa Cardinez, Nishi Kumari, Christina E Sparbier, Enid Y N Lam, Miriam M Yeung, Sylvain Garciaz, James A Kuzich, Doen Ming Ong, Fiona C Brown, Yih-Chih Chan, Dane Vassiliadis, Elanor N Wainwright, Ali Motazedian, Andrea Gillespie, Katie A Fennell, Junyun Lai, Imran G House, Laura Macpherson, Ching-Seng Ang, Sarah-Jane Dawson, Paul A Beavis, Andrew H Wei, Marian L Burr, Mark A Dawson
Journal: Cancer Cell
PubMed ID: 36179686
Doi: 10.1016/j.ccell.2022.09.007
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Involvement of transmembrane protein 184a during angiogenesis in zebrafish embryos
Authors: Cassandra J Field, Alexis M Perez, Taryn Samet, Victoria Ricles, M Kathryn Iovine, Linda J Lowe-Krentz
Journal: Front Physiol
PubMed ID: 36117693
Doi: 10.3389/fphys.2022.845407
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High-efficiency recombinant protein purification using mCherry and YFP nanobody affinity matrices
Authors: Anh T Q Cong, Taylor L Witter, Matthew J Schellenberg
Journal: Protein Sci
PubMed ID: 36040252
Doi: 10.1002/pro.4383
Products & Services: Plasmid DNA Preparation   
Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis
Authors: Yong Chen, Zhuyin Wu, Shijia Huang, Xiaoxia Wang, Sijia He, Lin Liu, Yurong Hu, Li Chen, Peng Chen, Songzi Liu, Shengqi He, Bo Shan, Ling Zheng, Sheng-Zhong Duan, Zhiyin Song, Lei Jiang, Qiong A Wang, Zhenji Gan, Bao-Liang Song, Jianmiao Liu, Liangyou Rui, Mengle Shao, Yong Liu
Journal: Nat Metab
PubMed ID: 36123394
Doi: 10.1038/s42255-022-00631-8
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Residues L55 and W69 of Tva Mediate Entry of Subgroup A Avian Leukosis Virus
Authors: Yuntong Chen, Suyan Wang, Xinyi Li, Mengmeng Yu, Peng Liu, Lingzhai Meng, Ru Guo, Xiaoyan Feng, Aijing Liu, Xiaole Qi, Kai Li, Li Gao, Qing Pan, Yanping Zhang, Changjun Liu, Hongyu Cui, Xiaomei Wang, Yulong Gao
Journal: J Virol
PubMed ID: 36069550
Doi: 10.1128/jvi.00678-22
Structure of the PAPP-A complex reveals mechanism of substrate recognition
Authors: Russell A Judge, Janani Sridar, Kathryn Tunyasuvunakool, Rinku Jain, John C K Wang, Christna Ouch, Jun Xu, Amirhossein Mafi, Aaron H Nile, Clint Remarcik, Corey L Smith, Crystal Ghosh, Chen Xu, Vincent Stoll, John Jumper, Amoolya H Singh, Dan Eaton, Qi Hao
Journal: Nat Commun
PubMed ID: 36127359
Doi: 10.1038/s41467-022-33175-2
Multiplex real-time PCR for the detection and differentiation of equid gammaherpesvirus 2 and 5
Authors: Flavia Fürer, Cornel Fraefel, Julia Lechmann
Journal: J Virol Methods
PubMed ID: 36087793
Doi: 10.1016/j.jviromet.2022.114615
Products & Services: Plasmid DNA Preparation   
The structure of a polyketide synthase bimodule core
Authors: Yves U Tittes, Dominik A Herbst, Solène F X Martin, Hugo Munoz-Hernandez, Roman P Jakob, Timm Maier
Journal: Sci Adv
PubMed ID: 36129979
Doi: 10.1126/sciadv.abo6918
A circular RNA derived from GLIS3 accelerates the proliferation of glioblastoma cells through competitively binding with miR-449c-5p to upregulate CAPG and GLIS3
Authors: Qingjiu Zhou, Mahati Shaya, Yalikun Kugeluke, Qiang Fu, Shaoshan Li, Yisireyili Dilimulati
Journal: BMC Neurosci
PubMed ID: 36114444
Doi: 10.1186/s12868-022-00736-6
Products & Services: Gene Synthesis   
Sulfanegen stimulates 3-mercaptopyruvate sulfurtransferase activity and ameliorates Alzheimer's disease pathology and oxidative stress in vivo
Authors: Swetha Pavani Rao, Wei Xie, Ye In Christopher Kwon, Nicholas Juckel, Jiashu Xie, Venkateshwara Rao Dronamraju, Robert Vince, Michael K Lee, Swati S More
Journal: Redox Biol
PubMed ID: 36183541
Doi: 10.1016/j.redox.2022.102484
Sec18 supports membrane fusion by promoting Sec17 membrane association
Authors: Amy Orr, William Wickner
Journal: Mol Biol Cell
PubMed ID: 36103252
Doi: 10.1091/mbc.E22-07-0274
Rapid Evaluation of Vaccine Booster Effectiveness against SARS-CoV-2 Variants
Authors: Hoi Lok Cheng, Sing Mei Lim, Huan Jia, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Jyoti Somani, Sharmila Sengupta, Dousabel M Y Tay, Patrina W L Chua, Abirami R, Sharon Y H Ling, Megan E McBee, Barnaby E Young, Hadley D Sikes, Peter R Preiser
Journal: Microbiol Spectr
PubMed ID: 36069616
Doi: 10.1128/spectrum.02257-22
Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models
Authors: Masoume Alipour, Majid Tebianian, Nahid Tofigh, Reyhaneh Sadat Taheri, Sayed Alireza Mousavi, Asal Naseri, Amin Ahmadi, Nayla Munawar, Koorosh Shahpasand
Journal: Neuropeptides
PubMed ID: 36087426
Doi: 10.1016/j.npep.2022.102285
Products & Services: Endotoxin Detection & Removal System   
The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues
Authors: Sinan Gai, Kajitha Suthagar, Karl J Shaffer, Wanting Jiao, Yacoba V T Minnow, Kayla Glockzin, Sean W Maatouk, Ardala Katzfuss, Thomas D Meek, Vern L Schramm, Peter C Tyler
Journal: Bioorg Med Chem
PubMed ID: 36209571
Doi: 10.1016/j.bmc.2022.117038
Products & Services: Custom Vector Construction   
The KdmB-EcoA-RpdA-SntB chromatin complex binds regulatory genes and coordinates fungal development with mycotoxin synthesis
Authors: Betim Karahoda, Lakhansing Pardeshi, Mevlut Ulas, Zhiqiang Dong, Niranjan Shirgaonkar, Shuhui Guo, Fang Wang, Kaeling Tan, Özlem Sarikaya-Bayram, Ingo Bauer, Paul Dowling, Alastair B Fleming, Brandon T Pfannenstiel, Dianiris Luciano-Rosario, Harald Berger, Stefan Graessle, Mohamed M Alhussain, Joseph Strauss, Nancy P Keller, Koon Ho Wong, Özgür Bayram
Journal: Nucleic Acids Res
PubMed ID: 36095118
Doi: 10.1093/nar/gkac744
Products & Services: Polyclonal Antibody Services   
A Comparison of Dinoflagellate Thiolation Domain Binding Proteins Using In Vitro and Molecular Methods
Authors: Ernest Williams, Tsvetan Bachvaroff, Allen Place
Journal: Mar Drugs
PubMed ID: 36135770
Doi: 10.3390/md20090581
White spot syndrome virus directly activates mTORC1 signaling to facilitate its replication via polymeric immunoglobulin receptor-mediated infection in shrimp
Authors: Pan-Pan Hong, Cang Li, Guo-Juan Niu, Xiao-Fan Zhao, Jin-Xing Wang
Journal: PLoS Pathog
PubMed ID: 36067252
Doi: 10.1371/journal.ppat.1010808
Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis
Authors: Marcela A Ferrada, Sinisa Savic, Daniela Ospina Cardona, Jason C Collins, Hugh Alessi, Fernanda Gutierrez-Rodrigues, Dinesh Babu Uthaya Kumar, Lorena Wilson, Wendy Goodspeed, James S Topilow, Julie J Paik, James A Poulter, Tanaz A Kermani, Matthew J Koster, Kenneth J Warrington, Catherine Cargo, Rachel S Tattersall, Christopher J A Duncan, Anna Cantor, Patrycja Hoffmann, Elspeth M Payne, Hanna Bonnekoh, Karoline Krause, Edward W Cowen, Katherine R Calvo, Bhavisha A Patel, Amanda K Ombrello, Daniel L Kastner, Neal S Young, Achim Werner, Peter C Grayson, David B Beck
Journal: Blood
PubMed ID: 35793467
Doi: 10.1182/blood.2022016985
Products & Services: Gene Synthesis   
Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function
Authors: Marthe S Christie, Mikko Laitaoja, Aasne K Aarsand, Juha P Kallio, Helene J Bustad
Journal: FEBS Open Bio
PubMed ID: 36115019
Doi: 10.1002/2211-5463.13490
Products & Services: Gene Synthesis   
Screening of glycosylase activity on oxidative derivatives of methylcytosine: Pedobacter heparinus SMUG2 as a formylcytosine- and carboxylcytosine-DNA glycosylase
Authors: Chenyan Chang, Ye Yang, Jing Li, Sung-Hyun Park, Guang-Chen Fang, Chuan Liang, Weiguo Cao
Journal: DNA Repair (Amst)
PubMed ID: 36179537
Doi: 10.1016/j.dnarep.2022.103408
Products & Services: Mammalian Expression   
Identification and functional analysis of histone 12-like in red sea bream (Pagrus major)
Authors: Lianfei Song, Maqsood Ahmed Soomro, Lingshu Wang, Yuting Song, Guobin Hu
Journal: Dev Comp Immunol
PubMed ID: 36087785
Doi: 10.1016/j.dci.2022.104529
A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts
Authors: Julie-Anne Gabelich, Josephine Grützke, Florian Kirscht, Oliver Popp, Joachim M Matz, Gunnar Dittmar, Melanie Rug, Alyssa Ingmundson
Journal: PLoS Pathog
PubMed ID: 36126089
Doi: 10.1371/journal.ppat.1010846
Products & Services: PCR Cloning and Subcloning   
Squid Suckerin-Spider Silk Fusion Protein Hydrogel for Delivery of Mesenchymal Stem Cell Secretome to Chronic Wounds
Authors: Kenrick Koh, Jun Kit Wang, James Xiao Yuan Chen, Shu Hui Hiew, Hong Sheng Cheng, Bartosz Gabryelczyk, Marcus Ivan Gerard Vos, Yun Sheng Yip, Liyan Chen, Radoslaw M Sobota, Damian Kang Keat Chua, Nguan Soon Tan, Chor Yong Tay, Ali Miserez
Journal: Adv Healthc Mater
PubMed ID: 36177679
Doi: 10.1002/adhm.202201900
Anti-SARS-CoV-2 immunoadhesin remains effective against Omicron and other emerging variants of concern
Authors: Hadas Cohen-Dvashi, Jonathan Weinstein, Michael Katz, Maayan Eilon-Ashkenazy, Yuval Mor, Amir Shimon, Hagit Achdout, Hadas Tamir, Tomer Israely, Romano Strobelt, Maya Shemesh, Liat Stoler-Barak, Ziv Shulman, Nir Paran, Sarel Jacob Fleishman, Ron Diskin
Journal: iScience
PubMed ID: 36188189
Doi: 10.1016/j.isci.2022.105193
Products & Services: Mammalian Expression   
DNA hypermethylation of promoter and reduction of hepatic Kiss1r in female rats with type 2 diabetes
Authors: Kamil Ziarniak, Tony Yang, Cayla Boycott, Megan Beetch, Maciej Sassek, Emilia Grzeda, Yuexi Ma, Joanna H Sliwowska, Barbara Stefanska
Journal: Epigenetics
PubMed ID: 36094166
Doi: 10.1080/15592294.2022.2119120
Products & Services: Gene Synthesis   
HSC70 is a novel binding partner involved in the capture of immunoglobulins on B cells in the NOD mouse
Authors: Emma Renman, Rifat Ekici, Mia Sundström, Kristina Lejon
Journal: Autoimmunity
PubMed ID: 36120986
Doi: 10.1080/08916934.2022.2117307
Products & Services: Recombinant Proteins   
Teaching an old 'doc' new tricks for algal biotechnology: Strategic filter use enables multi-scale fluorescent protein signal detection
Authors: Sergio Gutiérrez, Gordon B Wellman, Kyle J Lauersen
Journal: Front Bioeng Biotechnol
PubMed ID: 36213064
Doi: 10.3389/fbioe.2022.979607
Products & Services: Plasmid DNA Preparation   
Molecular study on recombinant cold-adapted, detergent- and alkali stable esterase (EstRag) from Lysinibacillus sp.: a member of family VI.
Authors: Amira A Matrawy, Ahmed I Khalil, Amira M Embaby
Journal: World J Microbiol Biotechnol .
PubMed ID: 36070019
Doi: 10.1007/s11274-022-03402-5
Products & Services: Gene Synthesis   
A plant virus hijacks phosphatidylinositol-3,5-bisphosphate to escape autophagic degradation in its insect vector
Authors: Haitao Wang, Jianhua Zhang, Haoqiu Liu, Man Wang, Yan Dong, Yijun Zhou, Sek-Man Wong, Kai Xu, Qiufang Xu
Journal: Autophagy
PubMed ID: 36093594
Doi: 10.1080/15548627.2022.2116676
HOXB13 facilitates hepatocellular carcinoma progression by activating AKT/mTOR signaling pathway
Authors: Miao Li, Tingting Tan, Yu Geng, Yue Tao, Jie Pan, Jun Zhang, Qin Xu, Han Shen, Lingyun Zuo, Yuxin Chen
Journal: Ann Hepatol
PubMed ID: 36179794
Doi: 10.1016/j.aohep.2022.100759
Products & Services: CRISPR Plasmids   
Structural basis for directional chitin biosynthesis
Authors: Wei Chen, Peng Cao, Yuansheng Liu, Ailing Yu, Dong Wang, Lei Chen, Rajamanikandan Sundarraj, Zhiguang Yuchi, Yong Gong, Hans Merzendorfer, Qing Yang
Journal: Nature
PubMed ID: 36131020
Doi: 10.1038/s41586-022-05244-5
Products & Services: Recombinant Antibody Expression   
Characterization and Expression Analysis of Regeneration-Associated Protein (Aj-Orpin) during Intestinal Regeneration in the Sea Cucumber
Authors: Fang Su, Lina Sun, Xiaoni Li, Wei Cui, Hongsheng Yang
Journal: Mar Drugs
PubMed ID: 36135757
Doi: 10.3390/md20090568
Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer
Authors: Demetra P Kelenis, Kathia E Rodarte, Rahul K Kollipara, Karine Pozo, Shreoshi Pal Choudhuri, Kyle B Spainhower, Sarah J Wait, Victor Stastny, Trudy G Oliver, Jane E Johnson
Journal: Cancer Res
PubMed ID: 35748745
Doi: 10.1158/0008-5472.CAN-21-3713
Products & Services: GenParts™ DNA Fragments   
Proton-driven alternating access in a spinster lipid transporter
Authors: Reza Dastvan, Ali Rasouli, Sepehr Dehghani-Ghahnaviyeh, Samantha Gies, Emad Tajkhorshid
Journal: Nat Commun
PubMed ID: 36055994
Doi: 10.1038/s41467-022-32759-2
Products & Services: Custom Vector Construction   
Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer
Authors: Duy T Nguyen, Wei Yang, Arun Renganathan, Cody Weimholt, Duminduni H Angappulige, Thanh Nguyen, Robert W Sprung, Gerald L Andriole, Eric H Kim, Nupam P Mahajan, Kiran Mahajan
Journal: Clin Cancer Res
PubMed ID: 35849143
Doi: 10.1158/1078-0432.CCR-21-3603
Products & Services: Peptide Synthesis   
A lentiviral vector expressing a dendritic cell-targeting multimer induces mucosal anti-mycobacterial CD4 T-cell immunity
Authors: François Anna, Jodie Lopez, Fanny Moncoq, Catherine Blanc, Pierre Authié, Amandine Noirat, Ingrid Fert, Philippe Souque, Fabien Nevo, Alexandre Pawlik, David Hardy, Sophie Goyard, Denis Hudrisier, Roland Brosch, Françoise Guinet, Olivier Neyrolles, Pierre Charneau, Laleh Majlessi
Journal: Mucosal Immunol
PubMed ID: 36104497
Doi: 10.1038/s41385-022-00566-z
Products & Services: Codon Optimization   
Kinetic Characterization and Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferases
Authors: Kayla Glockzin, Demetrios Kostomiris, Yacoba V T Minnow, Kajitha Suthagar, Keith Clinch, Sinan Gai, Joshua N Buckler, Vern L Schramm, Peter C Tyler, Thomas D Meek, Ardala Katzfuss
Journal: Biochemistry
PubMed ID: 36193631
Doi: 10.1021/acs.biochem.2c00312
Products & Services: Custom Vector Construction   
Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment
Authors: Ye Sun, Jie Zhao, Qiang Wu, Yuxin Zhang, Yongqing You, Wenbo Jiang, Kerong Dai
Journal: NPJ Regen Med
PubMed ID: 36114225
Doi: 10.1038/s41536-022-00250-7
Products & Services: Gene Synthesis   

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