至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Extracellular ATP elicits DORN1-mediated RBOHD phosphorylation to regulate stomatal aperture.

Nat Commun. 2017; 
Chen D, Cao Y,, Li H, Kim D, Ahsan N,, Thelen J, Stacey G,.
Products/Services Used Details Operation
Bacterial Expression System coli and affinity purified using the Glutathione Resin (GenScript) and TALON® Metal Affinity Resin (Clontech), respectively. Get A Quote

摘要

In addition to acting as a cellular energy source, ATP can also act as a damage-associated molecular pattern in both animals and plants. Stomata are leaf pores that control gas exchange and, therefore, impact critical functions such as photosynthesis, drought tolerance, and also are the preferred entry point for pathogens. Here we show the addition of ATP leads to the rapid closure of leaf stomata and enhanced resistance to the bacterial pathogen Psuedomonas syringae. This response is mediated by ATP recognition by the receptor DORN1, followed by direct phosphorylation of the NADPH oxidase RBOHD, resulting in elevated production of reactive oxygen species and stomatal closure. Mutation of DORN1 phosphorylation ... More

关键词