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MiR-379-5p aggravates experimental autoimmune uveitis in mice via the regulation of SEMA3A
Authors: Mohan Li, Xiang Gao, Kou Liu, Ning Bao, Zhengxuan Jiang
Journal: Autoimmunity
PubMed ID: 34060391
Doi: 10.1080/08916934.2021.1931841
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Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs
Authors: Shira Weingarten-Gabbay, Susan Klaeger, Siranush Sarkizova, Leah R Pearlman, Da-Yuan Chen, Kathleen M E Gallagher, Matthew R Bauer, Hannah B Taylor, W Augustine Dunn, Christina Tarr, John Sidney, Suzanna Rachimi, Hasahn L Conway, Katelin Katsis, Yuntong Wang, Del Leistritz-Edwards, Melissa R Durkin, Christopher H Tomkins-Tinch, Yaara Finkel, Aharon Nachshon, Matteo Gentili, Keith D Rivera, Isabel P Carulli, Vipheaviny A Chea, Abishek Chandrashekar, Cansu Cimen Bozkus, Mary Carrington, Nina Bhardwaj, Dan H Barouch, Alessandro Sette, Marcela V Maus, Charles M Rice, Karl R Clauser, Derin B Keskin, Daniel C Pregibon, Nir Hacohen, Steven A Carr, Jennifer G Abelin, Mohsan Saeed, Pardis C Sabeti
Journal: Cell
PubMed ID: 34171305
Doi: 10.1016/j.cell.2021.05.046
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Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1 and BCR-ABL1
Authors: Afsar Ali Mian, Isabella Haberbosch, Hazem Khamaisie, Abed Agbarya, Larissa Pietsch, Elizabeh Eshel, Dally Najib, Claudia Chiriches, Oliver Gerhard Ottmann, Oliver Hantschel, Ricardo M Biondi, Martin Ruthardt, Jamal Mahajna
Journal: Ann Hematol
PubMed ID: 34110462
Doi: 10.1007/s00277-020-04357-z
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Therapeutic Potential of HLA-I Polyreactive mAbs Mimicking the HLA-I Polyreactivity and Immunoregulatory Functions of IVIg
Authors: Mepur H Ravindranath, Fatiha El Hilali, Edward J Filippone
Journal: Vaccines (Basel)
PubMed ID: 34205517
Doi: 10.3390/vaccines9060680
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Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation
Authors: Sushila A Toulmin, Chaitali Bhadiadra, Andrew J Paris, Jeffrey H Lin, Jeremy Katzen, Maria C Basil, Edward E Morrisey, G Scott Worthen, Laurence C Eisenlohr
Journal: Nat Commun
PubMed ID: 34183650
Doi: 10.1038/s41467-021-23619-6
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A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage
Authors: Frank Gambino, Wanbo Tai, Denis Voronin, Yi Zhang, Xiujuan Zhang, Juan Shi, Xinyi Wang, Ning Wang, Lanying Du, Liang Qiao
Journal: Cell Rep
PubMed ID: 33979612
Doi: 10.1016/j.celrep.2021.109107
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IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4 T cell responses
Authors: Binh L Phong, Shaina J D'Souza, Robin L Baudier, Eric Wu, Victoria E Immethun, David L Bauer, James B McLachlan
Journal: Sci Rep
PubMed ID: 33958642
Doi: 10.1038/s41598-021-88956-4
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Minimally invasive brain injections for viral-mediated transgenesis: New tools for behavioral genetics in sticklebacks
Authors: Noelle James, Alison Bell
Journal: PLoS ONE
PubMed ID: 33999965
Doi: 10.1371/journal.pone.0251653
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Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency
Authors: Seula Shin, Hao Zhou, Chenxi He, Yanjun Wei, Yunfei Wang, Takashi Shingu, Ailiang Zeng, Shaobo Wang, Xin Zhou, Hongtao Li, Qiang Zhang, Qinling Mo, Jiafu Long, Fei Lan, Yiwen Chen, Jian Hu
Journal: Nat Commun
PubMed ID: 34021134
Doi: 10.1038/s41467-021-22782-0
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S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
Authors: Dongqin Chen, Fengsheng Hao, Huiqi Mu, Nagib Ahsan, Jay J Thelen, Gary Stacey
Journal: Nat Commun
PubMed ID: 33980819
Doi: 10.1038/s41467-021-22854-1
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