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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection

Authors: Cory J Knudson, Pedro Alves-Peixoto, Hiromi Muramatsu, Colby Stotesbury, Lingjuan Tang, Paulo J C Lin, Ying K Tam, Drew Weissman, Norbert Pardi, Luis J Sigal

Journal: Mol Ther

PubMed ID: 33992803

Doi: 10.1016/j.ymthe.2021.05.011

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Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis

Authors: Xin Zhou, Seula Shin, Chenxi He, Qiang Zhang, Matthew N Rasband, Jiangong Ren, Congxin Dai, Rocío I Zorrilla-Veloz, Takashi Shingu, Liang Yuan, Yunfei Wang, Yiwen Chen, Fei Lan, Jian Hu

Journal: Elife

PubMed ID: 33942715

Doi: 10.7554/eLife.60467

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The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity

Authors: Claire Fergus, Mashael Al-Qasem, Michelle Cotter, Ciara M McDonnell, Emiliano Sorrentino, Franciane Chevot, Karsten Hokamp, Mathias O Senge, John M Southern, Stephen J Connon, Vincent P Kelly

Journal: Nucleic Acids Res

PubMed ID: 34009357

Doi: 10.1093/nar/gkab289

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PD-L2 suppresses T cell signaling via coinhibitory microcluster formation and SHP2 phosphatase recruitment

Authors: Tomohiro Takehara, Ei Wakamatsu, Hiroaki Machiyama, Wataru Nishi, Katsura Emoto, Miyuki Azuma, Kenzo Soejima, Koichi Fukunaga, Tadashi Yokosuka

Journal: Commun Biol

PubMed ID: 33990697

Doi: 10.1038/s42003-021-02111-3

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A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies

Authors: Chase D McCann, Christiaan H van Dorp, Ali Danesh, Adam R Ward, Thomas R Dilling, Talia M Mota, Elizabeth Zale, Eva M Stevenson, Shabnum Patel, Chanson J Brumme, Winnie Dong, Douglas S Jones, Thomas L Andresen, Bruce D Walker, Zabrina L Brumme, Catherine M Bollard, Alan S Perelson, Darrell J Irvine, R Brad Jones

Journal: J Exp Med

PubMed ID: 33988715

Doi: 10.1084/jem.20201908

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Calmodulin complexes with brain and muscle creatine kinase peptides

Authors: Janina Sprenger, Anda Trifan, Neal Patel, Ashley Vanderbeck, Jenny Bredfelt, Emad Tajkhorshid, Roger Rowlett, Leila Lo Leggio, Karin S Åkerfeldt, Sara Linse

Journal: Curr Res Struct Biol

PubMed ID: 34235492

Doi: 10.1016/j.crstbi.2021.05.001

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Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

Authors: Brian J Ward, Philipe Gobeil, Annie Séguin, Judith Atkins, Iohann Boulay, Pierre-Yves Charbonneau, Manon Couture, Marc-André D'Aoust, Jiwanjeet Dhaliwall, Carolyn Finkle, Karen Hager, Asif Mahmood, Alexander Makarkov, Matthew P Cheng, Stéphane Pillet, Patricia Schimke, Sylvie St-Martin, Sonia Trépanier, Nathalie Landry

Journal: Nat Med

PubMed ID: 34007070

Doi: 10.1038/s41591-021-01370-1

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Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response

Authors: Silvia Vaena, Paramita Chakraborty, Han Gyul Lee, Alhaji H Janneh, Mohamed Faisal Kassir, Gyda Beeson, Zachariah Hedley, Ahmet Yalcinkaya, M Hanief Sofi, Hong Li, Monica L Husby, Robert V Stahelin, Xue-Zhong Yu, Shikhar Mehrotra, Besim Ogretmen

Journal: Cell Rep

PubMed ID: 33951438

Doi: 10.1016/j.celrep.2021.109076

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Drp1-dependent peptide reverse mitochondrial fragmentation, a homeostatic response in Friedreich ataxia

Authors: Joseph Johnson, Elizabeth Mercado-Ayón, Elisia Clark, David Lynch, Hong Lin

Journal: Pharmacol Res Perspect

PubMed ID: 33951329

Doi: 10.1002/prp2.755

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BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G activation at early endosomes

Authors: Shane C Wright, Viktoriya Lukasheva, Christian Le Gouill, Hiroyuki Kobayashi, Billy Breton, Samuel Mailhot-Larouche, Élodie Blondel-Tepaz, Nichelle Antunes Vieira, Claudio Costa-Neto, Madeleine Héroux, Nevin A Lambert, Lucas Tabajara Parreiras-E-Silva, Michel Bouvier

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33990469

Doi: 10.1073/pnas.2025846118

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