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CRISPR-dCas9 based DNA detection scheme for diagnostics in resource-limited settings
Authors: Michel Bengtson, Mitasha Bharadwaj, Oskar Franch, Jaco van der Torre, Veronique Meerdink, Henk Schallig, Cees Dekker
Journal: Nanoscale
PubMed ID: 35044397
Doi: 10.1039/d1nr06557b
Products & Services: Plasmid DNA Preparation   
An engineered bispecific human monoclonal antibody against SARS-CoV-2
Authors: Zhaohui Li, Shihua Li, Gen Zhang, Weiyu Peng, Zhen Chang, Xue Zhang, Zheng Fan, Yan Chai, Feiran Wang, Xin Zhao, Dedong Li, Rong Zhang, Zhanlong He, Weiwei Zou, Ke Xu, Wenwen Lei, Peipei Liu, Junfeng Hao, Jingjing Zhang, Litao Sun, Guizhen Wu, Shuguang Tan, George Fu Gao, Feng Gao, Yan Wu
Journal: Nat Immunol
PubMed ID: 35228696
Doi: 10.1038/s41590-022-01138-w
Products & Services: Stable Cell Lines   
Placental methylome reveals a 22q1333 brain regulatory gene locus associated with autism
Authors: Yihui Zhu, J Antonio Gomez, Benjamin I Laufer, Charles E Mordaunt, Julia S Mouat, Daniela C Soto, Megan Y Dennis, Kelly S Benke, Kelly M Bakulski, John Dou, Ria Marathe, Julia M Jianu, Logan A Williams, Orangel J Gutierrez Fugón, Cheryl K Walker, Sally Ozonoff, Jason Daniels, Luke P Grosvenor, Heather E Volk, Jason I Feinberg, M Daniele Fallin, Irva Hertz-Picciotto, Rebecca J Schmidt, Dag H Yasui, Janine M LaSalle
Journal: Genome Biol
PubMed ID: 35168652
Doi: 10.1186/s13059-022-02613-1
Products & Services: Polyclonal Antibody Services   
Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy
Authors: Hung X Nguyen, Tianyu Wu, Daniel Needs, Hengtao Zhang, Robin M Perelli, Sophia DeLuca, Rachel Yang, Michael Tian, Andrew P Landstrom, Craig Henriquez, Nenad Bursac
Journal: Nat Commun
PubMed ID: 35110560
Doi: 10.1038/s41467-022-28251-6
Products & Services: Codon Optimization   
Engineered EryF hydroxylase improving heterologous polyketide erythronolide B production in Escherichia coli
Authors: Zhifeng Liu, Jianlin Xu, Haili Liu, Yong Wang
Journal: Microb Biotechnol
PubMed ID: 35174640
Doi: 10.1111/1751-7915.14000
Products & Services: Codon Optimization   
Antibody responses to 2 doses of mRNA Covid vaccine in pediatric renal patients
Authors: Alison Lap-Tak Ma, Daniel Leung, Eugene Yu-Hin Chan, Stella Chim, Samuel Cheng, Fanny Tsz-Wai Ho, Wai-Ming Lai, Pak-Chiu Tong, Matthew Hon-Lam Lee, Wilfred Hing-Sang Wong, Sau Man Chan, Jaime Rosa Duque, Joseph Sriyal Malik Peiris, Yu-Lung Lau
Journal: Kidney Int
PubMed ID: 35231464
Doi: 10.1016/j.kint.2022.01.035
Telencephalic outputs from the medial entorhinal cortex are copied directly to the hippocampus
Authors: Sau Yee Tsoi, Merve Öncül, Ella Svahn, Mark Robertson, Zuzanna Bogdanowicz, Christina McClure, Gülşen Sürmeli
Journal: Elife
PubMed ID: 35188100
Doi: 10.7554/eLife.73162
Products & Services: PCR Cloning and Subcloning   
Performance evaluation of novel fluorescent-based lateral flow immunoassay (LFIA) for rapid detection and quantification of total anti-SARS-CoV-2 S-RBD binding antibodies in infected individuals
Authors: Farah M Shurrab, Nadin Younes, Duaa W Al-Sadeq, Na Liu, Hamda Qotba, Laith J Abu-Raddad, Gheyath K Nasrallah
Journal: Int J Infect Dis
PubMed ID: 35231609
Doi: 10.1016/j.ijid.2022.02.052
Products & Services: Catalog Antibody   
Elucidating the acid-base mechanisms underlying otolith overgrowth in fish exposed to ocean acidification
Authors: Garfield T Kwan, Martin Tresguerres
Journal: Sci Total Environ
PubMed ID: 35143791
Doi: 10.1016/j.scitotenv.2022.153690
Products & Services: Polyclonal Antibody Services   
Functional antibody-dependent cell mediated cytotoxicity (ADCC) responses to vaccine and circulating influenza strains following vaccination
Authors: Xuemin Chen, He-Ying Sun, Chun Yi Lee, Christina A Rostad, Jessica Trost, Rodrigo B Abreu, Michael A Carlock, Jason R Wilson, Shane Gansebom, Ted M Ross, David A Steinhauer, Evan J Anderson, Larry J Anderson
Journal: Virology
PubMed ID: 35255298
Doi: 10.1016/j.virol.2022.02.004
Products & Services: Plasmid DNA Preparation   
High level SARS-CoV-2 nucleocapsid refolding using mild condition for inclusion bodies solubilization: Application of high pressure at pH 90
Authors: Rosa Maria Chura-Chambi, Alvaro Rossan de Brandão Prieto-da-Silva, Matheus Martins Di Lela, João Ezequiel Oliveira, Patricia Estima Antonia Abreu, Luciana Regina Meireles, Heitor Franco de Andrade Junior, Ligia Morganti
Journal: PLoS ONE
PubMed ID: 35113919
Doi: 10.1371/journal.pone.0262591
Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection
Authors: John P Evans, Cong Zeng, Claire Carlin, Gerard Lozanski, Linda J Saif, Eugene M Oltz, Richard J Gumina, Shan-Lu Liu
Journal: Sci Transl Med
PubMed ID: 35166573
Doi: 10.1126/scitranslmed.abn8057
Products & Services: Custom Vector Construction   
Dissolving Microneedle Delivery of a Prophylactic HPV Vaccine
Authors: Sayoni Ray, David M Wirth, Oscar A Ortega-Rivera, Nicole F Steinmetz, Jonathan K Pokorski
Journal: Biomacromolecules
PubMed ID: 35139303
Doi: 10.1021/acs.biomac.1c01345
Products & Services: Catalog Peptides   
Discrepant serological findings in SARS-CoV-2 PCR negative, hospitalised patients with fever and acute respiratory symptoms during the pandemic
Authors: Gail Brenda Cross, Claire M Naftalin, Jinghao Nicholas Ngiam, Natasha Bagdasarian, Chek Meng Poh, Yun Shan Goh, Wan Ni Chia, Siti Naqiah Amrun, Sai Meng Tham, Hazel Teng, Rawan Alagha, Shoban Krishna Kumar, Shaun Shi Yan Tan, Lin Fa Wang, Paul Anantharajah Tambyah, Laurent Renia, Dale Fisher, Lisa F P Ng
Journal: J Med Virol
PubMed ID: 35171507
Doi: 10.1002/jmv.27656
Bioinformatic characterization of a triacylglycerol lipase produced by isolated from the decaying seed of
Authors: Benjamin O Ezema, Kingsley O Omeje, Roslyn M Bill, Alan D Goddard, Sabinus Oscar O Eze, Alfred Fernandez-Castane
Journal: J Biomol Struct Dyn
PubMed ID: 35147487
Doi: 10.1080/07391102.2022.2035821
Products & Services: Codon Optimization   
Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease
Authors: Gapisha Karunakaran, Yidai Yang, Véronique Tremblay, Zhibin Ning, Jade Martin, Amine Belaouad, Daniel Figeys, Joseph S Brunzelle, Patrick M Giguere, Alain Stintzi, Jean-François Couture
Journal: FEBS Lett
PubMed ID: 35122247
Doi: 10.1002/1873-3468.14295
Products & Services: Custom Vector Construction   
Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease
Authors: Gapisha Karunakaran, Yidai Yang, Véronique Tremblay, Zhibin Ning, Jade Martin, Amine Belaouad, Daniel Figeys, Joseph S Brunzelle, Patrick M Giguere, Alain Stintzi, Jean-François Couture
Journal: FEBS Lett
PubMed ID: 35122247
Doi: 10.1002/1873-3468.14295
Products & Services: Custom Vector Construction   
APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells
Authors: Yingying Liu, Xiaochuan Ma, Hui Yang, Xun Li, Yingli Ma, Brandon Ason, Suling Liu, Liaoyuan A Hu
Journal: Biochem J
PubMed ID: 35084016
Doi: 10.1042/BCJ20210813
Products & Services: Gene Synthesis   
Tetrahymena thermophila granule lattice protein 3 improves solubility of sexual stage malaria antigens expressed in Escherichia coli
Authors: Cengiz Akkale, Donna Marie Cassidy-Hanley, Theodore G Clark
Journal: Protein Expr Purif
PubMed ID: 35134517
Doi: 10.1016/j.pep.2022.106060
Products & Services: GenParts™ DNA Fragments   
Crp/fnr family protein binds to promoters of atxA and sodmn genes that regulate the expression of exotoxins in Bacillus anthracis
Authors: Divya Goel, Sudhir Kumar, Gopal Krishna Joshi, Prashant Rai, Rakesh Bhatnagar
Journal: Protein Expr Purif
PubMed ID: 35114377
Doi: 10.1016/j.pep.2022.106059
Products & Services: Recombinant Antibody Expression   
Discrepant serological findings in SARS-CoV-2 PCR negative, hospitalised patients with fever and acute respiratory symptoms during the pandemic
Authors: Gail Brenda Cross, Claire M Naftalin, Jinghao Nicholas Ngiam, Natasha Bagdasarian, Chek Meng Poh, Yun Shan Goh, Wan Ni Chia, Siti Naqiah Amrun, Sai Meng Tham, Hazel Teng, Rawan Alagha, Shoban Krishna Kumar, Shaun Shi Yan Tan, Lin Fa Wang, Paul Anantharajah Tambyah, Laurent Renia, Dale Fisher, Lisa F P Ng
Journal: J Med Virol
PubMed ID: 35171507
Doi: 10.1002/jmv.27656
Immunoaffinity monoliths for multiplexed extraction of preterm birth biomarkers from human blood serum in 3D printed microfluidic devices
Authors: Haifa M Almughamsi, Makella K Howell, Samuel R Parry, Joule E Esene, Jacob B Nielsen, Gregory P Nordin, Adam T Woolley
Journal: Analyst
PubMed ID: 35103723
Doi: 10.1039/d1an01365c
Products & Services: Recombinant Proteins   
Transformation of by for the Expression of the Hemagglutinin of Avian Influenza Virus H5
Authors: Inkar Castellanos-Huerta, Gabriela Gómez-Verduzco, Guillermo Tellez-Isaias, Guadalupe Ayora-Talavera, Bernardo Bañuelos-Hernández, Víctor Manuel Petrone-García, Gilberto Velázquez-Juárez, Isidro Fernández-Siurob
Journal: Microorganisms
PubMed ID: 35208815
Doi: 10.3390/microorganisms10020361
Products & Services: Codon Optimization   
Comparison of Neutralizing Antibody Responses at 6 Months Post Vaccination with BNT162b2 and AZD1222
Authors: Evangelos Terpos, Vangelis Karalis, Ioannis Ntanasis-Stathopoulos, Zoi Evangelakou, Maria Gavriatopoulou, Maria S Manola, Panagiotis Malandrakis, Despoina D Gianniou, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos
Journal: Biomedicines
PubMed ID: 35203547
Doi: 10.3390/biomedicines10020338
The Anticancer Effect of a Conjugated Antimicrobial Peptide Against Colorectal Cancer (CRC) Cells
Authors: Raed Obaid Saleh, Ihsan Naji Atiyah Essia, Saade Abdalkareem Jasim
Journal: J Gastrointest Cancer
PubMed ID: 35217999
Doi: 10.1007/s12029-021-00799-4
Products & Services: Peptide Synthesis   
Calcium and integrin-binding protein 1-like interacting with an integrin α-cytoplasmic domain facilitates cellular immunity in Helicoverpa armigera
Authors: Ming-Ming Zhang, Ling-Ling Luo, Yu Liu, Gui-Jie Wang, Huan-Huan Zheng, Xu-Sheng Liu, Jia-Lin Wang
Journal: Dev Comp Immunol
PubMed ID: 35231466
Doi: 10.1016/j.dci.2022.104379
Products & Services: Recombinant Antibody Expression   
Fitness benefits play a vital role in the retention of the Pi-ta susceptible alleles
Authors: Jia Liu, Suobing Zhang, Pengfei Xie, Long Wang, Jia-Yu Xue, Yanmei Zhang, Ruisen Lu, Yueyu Hang, Yue Wang, Xiaoqin Sun
Journal: Genetics
PubMed ID: 35143673
Doi: 10.1093/genetics/iyac019
Products & Services: Custom DNA/RNA Oligos   
Circular dichroism spectroscopic assessment of structural changes upon protein thermal unfolding at contrasting pH: Comparison with molecular dynamics simulations
Authors: Ponciano García-Gutiérrez, Menandro Camarillo-Cadena, Liliana I Vera-Robles, Rafael A Zubillaga, Andrés Hernández-Arana
Journal: Spectrochim Acta A Mol Biomol Spectrosc
PubMed ID: 35245803
Doi: 10.1016/j.saa.2022.121039
Products & Services: Gene Synthesis   
Impact of Superparamagnetic Iron Oxide Nanoparticles on THP-1 Monocytes and Monocyte-Derived Macrophages
Authors: Christina Polasky, Tim Studt, Ann-Kathrin Steuer, Kristin Loyal, Kerstin Lüdtke-Buzug, Karl-Ludwig Bruchhage, Ralph Pries
Journal: Front Mol Biosci
PubMed ID: 35211509
Doi: 10.3389/fmolb.2022.811116
Overexpression of sonic hedgehog enhances the osteogenesis in rat ectomesenchymal stem cells
Authors: Weijiang Wu, Zhe Wang, Zhijian Zhang, Wenjing Yang, Xin Fan, Jili Xu, Zhiqiang Huang, Qixiang Shao
Journal: Cell Tissue Bank
PubMed ID: 35147838
Doi: 10.1007/s10561-022-09994-4
Products & Services: Plasmid DNA Preparation   
Overexpression of sonic hedgehog enhances the osteogenesis in rat ectomesenchymal stem cells
Authors: Weijiang Wu, Zhe Wang, Zhijian Zhang, Wenjing Yang, Xin Fan, Jili Xu, Zhiqiang Huang, Qixiang Shao
Journal: Cell Tissue Bank
PubMed ID: 35147838
Doi: 10.1007/s10561-022-09994-4
Products & Services: Plasmid DNA Preparation   
Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines
Authors: Noëmi Johanna Roos, Riccardo Vincenzo Mancuso, Gerda Mawududzi Sanvee, Jamal Bouitbir, Stephan Krähenbühl
Journal: Food Chem Toxicol
PubMed ID: 35182693
Doi: 10.1016/j.fct.2022.112869
RNA interference targeting UL25 gene as a gene therapy approach against BHV-1
Authors: Elaheh Amjadimanesh, Azam Mokhtari, Behnaz Saffar
Journal: Res Vet Sci
PubMed ID: 35182967
Doi: 10.1016/j.rvsc.2022.02.007
Products & Services: Custom DNA/RNA Oligos   
Structural characterization of the ANTAR antiterminator domain bound to RNA
Authors: James L Walshe, Rezwan Siddiquee, Karishma Patel, Sandro F Ataide
Journal: Nucleic Acids Res
PubMed ID: 35150565
Doi: 10.1093/nar/gkac074
Products & Services: Gene Synthesis   
Structural characterization of the ANTAR antiterminator domain bound to RNA
Authors: James L Walshe, Rezwan Siddiquee, Karishma Patel, Sandro F Ataide
Journal: Nucleic Acids Res
PubMed ID: 35150565
Doi: 10.1093/nar/gkac074
Products & Services: Gene Synthesis   
Neoantigens as potential vaccines in hepatocellular carcinoma
Authors: David Repáraz, Marta Ruiz, Diana Llopiz, Leyre Silva, Enric Vercher, Belén Aparicio, Josune Egea, Ibon Tamayo-Uria, Sandra Hervás-Stubbs, Jorge García-Balduz, Carla Castro, Mercedes Iñarrairaegui, Maria Tagliamonte, Angela Mauriello, Beatrice Cavalluzzo, Luigi Buonaguro, Charlotte Rohrer, Kathrin Heim, Catrin Tauber, Maike Hofmann, Robert Thimme, Bruno Sangro, Pablo Sarobe
Journal: J Immunother Cancer
PubMed ID: 35193931
Doi: 10.1136/jitc-2021-003978
Products & Services: Gene Synthesis   
Hydroxychloroquine for prophylaxis of COVID-19 in health workers: A randomized clinical trial
Authors: Jorge Rojas-Serrano, Angelica Margarita Portillo-Vásquez, Ireri Thirion-Romero, Joel Vázquez-Pérez, Fidencio Mejía-Nepomuceno, Alejandra Ramírez-Venegas, Karla Midori Pérez-Kawabe, Rogelio Pérez-Padilla
Journal: PLoS ONE
PubMed ID: 35139097
Doi: 10.1371/journal.pone.0261980
Products & Services: Catalog Antibody   
Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry
Authors: Bertrand Simon, Hua Jane Lou, Clotilde Huet-Calderwood, Guangda Shi, Titus J Boggon, Benjamin E Turk, David A Calderwood
Journal: Nat Commun
PubMed ID: 35136069
Doi: 10.1038/s41467-022-28427-0
Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase
Authors: Sabrina Patzelt, Manuela Pigors, Heiko Steenbock, Leonard Diel, Katharina Boch, Lenche Chakievska, Sven Künzel, Hauke Busch, Anke Fähnrich, Jürgen Brinckmann, Enno Schmidt
Journal: Front Immunol
PubMed ID: 35197965
Doi: 10.3389/fimmu.2021.812627
A novel peptide-based electrochemical biosensor for breast cancer characterization over a poly 3-(3-aminophenyl) propionic acid matrix
Authors: Rafael da Fonseca Alves, Isabella Castro Martins, Diego Leoni Franco, Adriane das Graças Silva, Paula de Souza Santos, Luiz Ricardo Goulart, Yara Cristina de Paiva Maia, Alinne Tatiane Faria Silva, Thaise Gonçalves Araújo, Maria Del Pilar Taboada Sotomayor
Journal: Biosens Bioelectron
PubMed ID: 35217253
Doi: 10.1016/j.bios.2022.114081
Products & Services: DNA Sequencing   
Finger stick blood test to assess postvaccination SARS-CoV-2 neutralizing antibody response against variants
Authors: Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M Y Tay, Megan E McBee, Barnaby E Young, Paul A MacAry, Hadley D Sikes, Peter R Preiser
Journal: Bioeng Transl Med
PubMed ID: 35600666
Doi: 10.1002/btm2.10293
Regulation of integrin α5β1 conformational states and intrinsic affinities by metal ions and the ADMIDAS
Authors: Jordan M Anderson, Jing Li, Timothy A Springer
Journal: Mol Biol Cell
PubMed ID: 35108026
Doi: 10.1091/mbc.E21-11-0536
Products & Services: Catalog Antibody   
The receptor CgIL-17R1 expressed in granulocytes mediates the CgIL-17 induced haemocytes proliferation in Crassostrea gigas
Authors: Wanqing Cao, Weilin Wang, Siqi Fan, Jialuo Li, Qing Li, Shasha Wu, Lingling Wang, Linsheng Song
Journal: Dev Comp Immunol
PubMed ID: 35183562
Doi: 10.1016/j.dci.2022.104376
Genome-wide identification and functional characterization of gene family reveal their involvement in response to drought stress in
Authors: Guangzhen Shi, Xinxia Zhu
Journal: PeerJ
PubMed ID: 35186477
Doi: 10.7717/peerj.12883
Products & Services: Protein Tools   
Challenges of expressing recombinant human tissue factor as a secreted protein in
Authors: Mohammad Jalili-Nik, Mohammad Soukhtanloo, Majid Mojarrad, Mohammad Hadi Sadeghian, Baratali Mashkani
Journal: Prep Biochem Biotechnol
PubMed ID: 35133942
Doi: 10.1080/10826068.2021.2023823
Products & Services: Catalog Peptides   
Trans-seeding of Alzheimer-related tau protein by a yeast prion
Authors: Martin Flach, Cedric Leu, Alfonso Martinisi, Zhiva Skachokova, Stephan Frank, Markus Tolnay, Henning Stahlberg, David T Winkler
Journal: Alzheimers Dement
PubMed ID: 35142027
Doi: 10.1002/alz.12581
Products & Services: Mutant Libraries   
Development of a Nanoparticle Multiepitope DNA Vaccine against Virulent Infectious Bronchitis Virus Challenge
Authors: Yifeng Qin, Qingyuan Teng, Delan Feng, Yu Pei, Ye Zhao, Guozhong Zhang
Journal: J Immunol
PubMed ID: 35217582
Doi: 10.4049/jimmunol.2100909
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The protective effects of Mirtazapine against lipopolysaccharide (LPS)-induced brain vascular hyperpermeability
Authors: Yuehong Pu, Lei Zhao, Yao Xi, Yichun Xia, Yiming Qian
Journal: Bioengineered
PubMed ID: 35081868
Doi: 10.1080/21655979.2021.2024962
Products & Services: ORF cDNA Clones/MolecularCloud   
Trans-seeding of Alzheimer-related tau protein by a yeast prion
Authors: Martin Flach, Cedric Leu, Alfonso Martinisi, Zhiva Skachokova, Stephan Frank, Markus Tolnay, Henning Stahlberg, David T Winkler
Journal: Alzheimers Dement
PubMed ID: 35142027
Doi: 10.1002/alz.12581
Products & Services: Mutant Libraries   
Higher SARS-CoV-2 Spike Binding Antibody Levels and Neutralization Capacity 6 Months after Heterologous Vaccination with AZD1222 and BNT162b2
Authors: Brigitte Müller-Hilke, Franz Mai, Michael Müller, Johann Volzke, Emil C Reisinger
Journal: Vaccines (Basel)
PubMed ID: 35214780
Doi: 10.3390/vaccines10020322
Products & Services: Catalog Peptides   

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