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页码: 15/1026 每页显示数量

Nanobody-based immunosensor for the detection of H pylori in saliva

Authors: Mohammad Ia Ahmad, Célia G Amorim, Luay F Abu Qatouseh, Maria C B S M Montenegro

Journal: Biosens Bioelectron

PubMed ID: 38810413

Doi: 10.1016/j.bios.2024.116423

Products & Services: Gene Synthesis

Deletion of Asb15b gene can lead to a significant decrease in zebrafish intermuscular bone

Authors: Minghui Niu, Huamin Whang, Zhichao Wu, Shouwen Jiang, Liangbiao Chen

Journal: Gene

PubMed ID: 38754570

Doi: 10.1016/j.gene.2024.148561

CYP116B5-SOX: An artificial peroxygenase for drug metabolites production and bioremediation

Authors: Daniele Giuriato, Gianluca Catucci, Danilo Correddu, Giovanna Di Nardo, Gianfranco Gilardi

Journal: Biotechnol J

PubMed ID: 38719620

Doi: 10.1002/biot.202300664

Products & Services: Custom Vector Construction

Cellular metabolism of substance P produces neurokinin-1 receptor peptide agonists with diminished cyclic AMP signaling

Authors: Tamas Kriska, Jayashree Natarajan, Anja Herrnreiter, Sang-Kyu Park, Sandra L Pfister, Michael J Thomas, Alexander Widiapradja, Scott P Levick, William B Campbell

Journal: Am J Physiol Cell Physiol

PubMed ID: 38798270

Doi: 10.1152/ajpcell.00103.2024

Products & Services: Molecular Biology Reagents

Single-shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad, durable and protective systemic and mucosal immunity in mice

Authors: Nicholas You Zhi Cheang, Kai Sen Tan, Peck Szee Tan, Kiren Purushotorma, Wee Chee Yap, Kirsteen McInnes Tullett, Benson Yen Leong Chua, Aileen Ying-Yan Yeoh, Caris Qi Hui Tan, Xinlei Qian, Huixin Chen, Douglas Jie Wen Tay, Irina Caminschi, Yee Joo Tan, Paul Anthony Macary, Chee Wah Tan, Mireille Hanna Lahoud, Sylvie Alonso

Journal: Mol Ther

PubMed ID: 38715364

Doi: 10.1016/j.ymthe.2024.05.003

Products & Services: Serology SARS-Cov-2 detection kits

Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines

Authors: Mireya L Borrajo, Gustavo Lou, Shubaash Anthiya, Philipp Lapuhs, David Moreira Álvarez, Araceli Tobío, María Isabel Loza, Anxo Vidal, María José Alonso

Journal: Drug Deliv Transl Res

PubMed ID: 38811465

Doi: 10.1007/s13346-024-01635-5

Products & Services: Catalog Peptides

An integrated multi-omics approach reveals polymethoxylated flavonoid biosynthesis in Citrus reticulata cv Chachiensis

Authors: Jiawen Wen, Yayu Wang, Xu Lu, Huimin Pan, Dian Jin, Jialing Wen, Canzhi Jin, Sunil Kumar Sahu, Jianmu Su, Xinyue Luo, Xiaohuan Jin, Jiao Zhao, Hong Wu, E-Hu Liu, Huan Liu

Journal: Nat Commun

PubMed ID: 38734724

Doi: 10.1038/s41467-024-48235-y

Products & Services: Recombinant Proteins

Early Animal Origin of BACE1 APP/Aβ Proteolytic Function

Authors: James A Langeland, Lillian Baumann, Eva M DeYoung, Raphaela Angelina Varella, Nkatha Mwenda, Alejandro Aguirre, D Blaine Moore

Journal: Biology (Basel)

PubMed ID: 38785802

Doi: 10.3390/biology13050320

Products & Services: Gene Synthesis

Three in one: An effective and universal vaccine expressing heterologous tandem RBD trimer by rabies virus vector protects mice against SARS-CoV-2

Authors: Jingbo Huang, Weiqi Wang, Hailun Li, Yujie Bai, Yumeng Song, Cuicui Jiao, Hongli Jin, Pei Huang, Haili Zhang, Xianzhu Xia, Feihu Yan, Yuanyuan Li, Hualei Wang

Journal: Antiviral Res

PubMed ID: 38740191

Doi: 10.1016/j.antiviral.2024.105905

Products & Services: Gene Synthesis

Generation and evaluation of cancer binding capacity of HLA-A2-WT1 complex-targeting antibody

Authors: Xue Yao, Sandro Matosevic

Journal: Immunol Lett

PubMed ID: 38810886

Doi: 10.1016/j.imlet.2024.106881

Products & Services: Molecular Biology Reagents

Transcriptome dynamics of the BHK21 cell line in response to human coronavirus OC43 infection

Authors: Mianhuan Li, Yang Yang, Pusen Wang, Weitao Que, Lin Zhong, Zhao Cai, Yang Liu, Liang Yang, Yingxia Liu

Journal: Microbiol Res

PubMed ID: 38761489

Doi: 10.1016/j.micres.2024.127750

Products & Services: Proteins, Expression, Isolation and Analysis

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer

Authors: Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao

Journal: Front Pharmacol

PubMed ID: 38835669

Doi: 10.3389/fphar.2024.1392328

Products & Services: Gene Synthesis

Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity

Authors: Fanomezana M Ranaivoson, Rieke Bande, Isabell Cardaun, Antonio De Riso, Annette Gärtner, Pui Loke, Christina Reinisch, Prasuna Vogirala, Edward Beaumont

Journal: IUCrJ

PubMed ID: 38656308

Doi: 10.1107/S2052252524002549

Products & Services: Molecular Biology Reagents

CXCR3 participates in asymmetric division of mouse oocytes by modulating actin dynamics

Authors: Wei-Jian Li, Rong-Yang Li, Da-Yu Wang, Ming Shen, Hong-Lin Liu

Journal: Theriogenology

PubMed ID: 38788628

Doi: 10.1016/j.theriogenology.2024.05.028

Products & Services: Proteins, Expression, Isolation and Analysis

Intranasal Vaccination with a Respiratory-Syncytial-Virus-Based Virus-like Particle Displaying the G Protein Conserved Region Induces Severe Weight Loss and Pathology upon Challenge with Wildtype Respiratory Syncytial Virus

Authors: Megolhubino Terhüja, Manjunath Siddappa, Pramila Lamichhane, Chetan D Meshram, Timothy A Snider, Jerry W Ritchey, Antonius G P Oomens

Journal: Viruses

PubMed ID: 38932136

Doi: 10.3390/v16060843

Products & Services: Catalog Antibody

Modified Zhenwu Tang delays chronic renal failure progression by modulating oxidative stress and hypoxic responses in renal proximal tubular epithelial cells

Authors: Yuan-Yuan Zhang, Pei-Pei Jin, Deng-Zhou Guo, Dong Bian

Journal: Heliyon

PubMed ID: 38803876

Doi: 10.1016/j.heliyon.2024.e31265

Products & Services: Proteins, Expression, Isolation and Analysis

Systemic LPS Administration Stimulates the Activation of Non-Neuronal Cells in an Experimental Model of Spinal Muscular Atrophy

Authors: Eleni Karafoulidou, Evangelia Kesidou, Paschalis Theotokis, Chrystalla Konstantinou, Maria-Konstantina Nella, Iliana Michailidou, Olga Touloumi, Eleni Polyzoidou, Ilias Salamotas, Ofira Einstein, Athanasios Chatzisotiriou, Marina-Kleopatra Boziki, Nikolaos Grigoriadis

Journal: Cells

PubMed ID: 38727321

Doi: 10.3390/cells13090785

Products & Services: Proteins, Expression, Isolation and Analysis

Investigating the Antimicrobial Effects of a Novel Peptide Derived From Listeriolysin S on , and : An In Silico and In Vitro Study

Authors: Mojgan Sarabi Nobakht, Kaveh Bazyar, Mohammad Sadegh Ghalyanchi Langeroudi, Mandana Mirzaei, Mehdi Goudarzi, Ali Shivaee

Journal: Bioinform Biol Insights

PubMed ID: 38765021

Doi: 10.1177/11779322241252513

Products & Services: Catalog Peptides

SARS-CoV-2 Surveillance of Wild Mice and Rats in North American Cities

Authors: Lisa K F Lee, Chelsea G Himsworth, Natalie Prystajecky, Antonia Dibernardo, L Robbin Lindsay, Theresa M Albers, Rajeev Dhawan, Ken Henderson, Guy Mulder, Harveen K Atwal, Imara Beattie, Bruce K Wobeser, Michael H Parsons, Kaylee A Byers

Journal: Ecohealth

PubMed ID: 38748281

Doi: 10.1007/s10393-024-01679-6

Products & Services: Molecular Biology Reagents

Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes

Authors: Noam Levin, Sanghyun P Kim, Charles A Marquardt, Nolan R Vale, Zhiya Yu, Sivasish Sindiri, Jared J Gartner, Maria Parkhurst, Sri Krishna, Frank J Lowery, Nikolaos Zacharakis, Lior Levy, Todd D Prickett, Tiffany Benzine, Satyajit Ray, Robert V Masi, Billel Gasmi, Yong Li, Rafiqul Islam, Alakesh Bera, Stephanie L Goff, Paul F Robbins, Steven A Rosenberg

Journal: J Immunother Cancer

PubMed ID: 38816232

Doi: 10.1136/jitc-2023-008645

Products & Services: Gene Synthesis

Application of MALDI-MS for characterization of fucoidan hydrolysates and screening of endo-fucoidanase activity

Authors: Diego S Reyes-Weiss, Margot Bligh, Nanna Rhein-Knudsen, Jan-Hendrik Hehemann, Manuel Liebeke, Bjørge Westereng, Svein Jarle Horn

Journal: Carbohydr Polym

PubMed ID: 38858030

Doi: 10.1016/j.carbpol.2024.122317

Products & Services: Molecular Biology Reagents

Structural basis for raccoon dog receptor recognition by SARS-CoV-2

Authors: Fu-Chun Hsueh, Ke Shi, Alise Mendoza, Fan Bu, Wei Zhang, Hideki Aihara, Fang Li

Journal: PLoS Pathog

PubMed ID: 38709834

Doi: 10.1371/journal.ppat.1012204

Products & Services: Molecular Biology Reagents

Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease

Authors: Saykat Das, Jorunn Stamnaes, Lene S Høydahl, Christine Skagen, Knut E A Lundin, Jørgen Jahnsen, Ludvig M Sollid, Rasmus Iversen

Journal: J Autoimmun

PubMed ID: 38754235

Doi: 10.1016/j.jaut.2024.103241

Products & Services: Gene Synthesis

Development of multiplexed orthogonal base editor (MOBE) systems

Authors: Quinn T Cowan, Sifeng Gu, Wanjun Gu, Brodie L Ranzau, Tatum S Simonson, Alexis C Komor

Journal: Nat Biotechnol

PubMed ID: 38773305

Doi: 10.1038/s41587-024-02240-0

Products & Services: Codon Optimization

Retinal organoids with X-linked retinoschisis RS1 (E72K) mutation exhibit a photoreceptor developmental delay and are rescued by gene augmentation therapy

Authors: Chunwen Duan, Chengcheng Ding, Xihao Sun, Shengru Mao, Yuqin Liang, Xinyu Liu, Xiaoyan Ding, Jiansu Chen, Shibo Tang

Journal: Stem Cell Res Ther

PubMed ID: 38816767

Doi: 10.1186/s13287-024-03767-4

Products & Services: Molecular Biology Reagents

The Hansenula polymorpha mitochondrial carrier family protein Mir1 is dually localized at peroxisomes and mitochondria

Authors: Marc Pilegaard Pedersen, Justina C Wolters, Rinse de Boer, Arjen M Krikken, Ida J van der Klei

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38702017

Doi: 10.1016/j.bbamcr.2024.119742

Products & Services: Codon Optimization

Loss of a conserved C-terminal region of the AtrR transcriptional regulator leads to a gene-specific defect in target gene expression

Authors: Shivani Ror, Mark A Stamnes, W Scott Moye-Rowley

Journal: biorxiv

PubMed ID: 38826412

Doi: 10.1101/2024.05.22.595332

Products & Services: Molecular Biology Reagents

The mitochondrial protease ClpP is a druggable target that controls VSMC phenotype by a SIRT1-dependent mechanism

Authors: Felipe Paredes, Holly C Williams, Xuesong Liu, Claire Holden, Bethany Bogan, Yu Wang, Kathryn M Crotty, Samantha M Yeligar, Alvaro A Elorza, Zhiyong Lin, Amir Rezvan, Alejandra San Martin

Journal: Redox Biol

PubMed ID: 38823208

Doi: 10.1016/j.redox.2024.103203

Products & Services: Proteins, Expression, Isolation and Analysis

Assessing the Impact of Novel Exon 11 Variants on Pre-mRNA Splicing

Authors: Halla Elshwekh, Inas M Alhudiri, Adam Elzagheid, Nabil Enattah, Yasmine Abbassi, Lubna Abou Assali, Ilenia Marino, Cristiana Stuani, Emanuele Buratti, Maurizio Romano

Journal: Cells

PubMed ID: 38786046

Doi: 10.3390/cells13100824

Products & Services: Gene Synthesis

Prominin 1 is crucial for the early development of photoreceptor outer segments

Authors: Sila Yanardag, Scott Rhodes, Thamaraiselvi Saravanan, Tongju Guan, Visvanathan Ramamurthy

Journal: Sci Rep

PubMed ID: 38714794

Doi: 10.1038/s41598-024-60989-5

Products & Services: Proteins, Expression, Isolation and Analysis

Virus-like particles expressing microneme-associated antigen of Plasmodium berghei confer better protection than those expressing apical membrane antigen 1

Authors: Min-Ju Kim, Ki Back Chu, Keon-Woong Yoon, Hae-Ji Kang, Dong-Hun Lee, Eun-Kyung Moon, Fu-Shi Quan

Journal: Parasites Hosts Dis

PubMed ID: 38835260

Doi: 10.3347/PHD.24017

Products & Services: Codon Optimization

Characterization of an agmatine N-acetyltransferase from Bactrocera dorsalis that modulates ovary development

Authors: Fei-Yue Teng, Ji-Mei Feng, Fu-Cai Ma, Zhuo-Xin Wang, Yong-Yue Lu, Yi-Xiang Qi

Journal: Insect Biochem Mol Biol

PubMed ID: 38734116

Doi: 10.1016/j.ibmb.2024.104130

Products & Services: Molecular Biology Reagents

Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease

Authors: Alexandra M D'Ordine, Gerwald Jogl, John M Sedivy

Journal: Nat Commun

PubMed ID: 38719805

Doi: 10.1038/s41467-024-48066-x

Products & Services: Molecular Biology Reagents

A Naturally Active Spy Transposon Discovered from the Insect Genome of Colletes gigas as a Promising Novel Gene Transfer Tool

Authors: Mohamed Diaby, Han Wu, Bo Gao, Shasha Shi, Bingqing Wang, Saisai Wang, Yali Wang, Zherui Wu, Cai Chen, Xiaoyan Wang, Chengyi Song

Journal: Adv Sci (Weinh)

PubMed ID: 38774947

Doi: 10.1002/advs.202400969

Products & Services: ORF cDNA Clones/MolecularCloud

Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4 regulatory T cells by regulating IL2RA

Authors: Syed Bilal Ahmad Andrabi, Ubaid Ullah Kalim, Senthil Palani, Mohd Moin Khan, Meraj Hasan Khan, Jimmy Fagersund, Julius Orpana, Niklas Paulin, Kedar Batkulwar, Sini Junttila, Tanja Buchacher, Toni Grönroos, Lea Toikka, Tea Ammunet, Partho Sen, Matej Orešič, Venla Kumpulainen, Johanna E E Tuomisto, Rahul Sinha, Alexander Marson, Omid Rasool, Laura L Elo, Riitta Lahesmaa

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38805281

Doi: 10.1073/pnas.2315363121

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SLC15A3 is transcriptionally regulated by HIF1α and p65 to worsen neuroinflammation in experimental ischemic stroke

Authors: Shan Yu, Jinghui Yang, Rui Zhang, Qian Guo, Lu Wang

Journal: Mol Neurobiol

PubMed ID: 38717559

Doi: 10.1007/s12035-024-04191-8

Products & Services: Proteins, Expression, Isolation and Analysis

The G932C mutation of chitin synthase 1 gene (CHS1) mediates buprofezin resistance as confirmed by CRISPR/Cas9-mediated knock-in approach in the brown planthopper, Nilaparvata lugens

Authors: Fan Zhang, Yan-Chao Zhang, Zhi-Tao Yu, Bing Zeng, Hao Sun, Yu-Qiu Xie, Kun Yan Zhu, Cong-Fen Gao

Journal: Pestic Biochem Physiol

PubMed ID: 38879307

Doi: 10.1016/j.pestbp.2024.105953

Products & Services: Codon Optimization

Recombinant Bile Salt Hydrolase Enhances the Inhibition Efficiency of Taurodeoxycholic Acid against Virulence

Authors: Tahrir Alenezi, Bilal Alrubaye, Ying Fu, Janashrit Shrestha, Samar Algehani, Hong Wang, Rohana Liyanage, Xiaolun Sun

Journal: Pathogens

PubMed ID: 38921762

Doi: 10.3390/pathogens13060464

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Antigen-level resolution of commensal-specific B cell responses can be enabled by phage display screening coupled with B cell tetramers

Authors: Sheenam Verma, Matthew J Dufort, Tayla M Olsen, Samantha Kimmel, Jasmine C Labuda, Sam Scharffenberger, Andrew T McGuire, Oliver J Harrison

Journal: Immunity

PubMed ID: 38723638

Doi: 10.1016/j.immuni.2024.04.014

Products & Services: Molecular Biology Reagents

A cell cycle regulator, E2F2, and glucocorticoid receptor cooperatively transactivate the bovine alphaherpesvirus 1 immediate early transcription unit 1 promoter

Authors: Fouad S El-Mayet, Clinton Jones

Journal: J Virol

PubMed ID: 38771044

Doi: 10.1128/jvi.00423-24

Products & Services: Molecular Biology Reagents

Identification of key genes affecting ventilator-induced diaphragmatic dysfunction in diabetic mice

Authors: Rongchun Xing, Haibo Yu, Jiangtao Yu, Rong Zeng, Zhijun Xiang, Haoli Ma, Gang Li, Yan Zhao

Journal: Front Genet

PubMed ID: 38784031

Doi: 10.3389/fgene.2024.1387688

Products & Services: Gene Synthesis

The three-dimensional structure of DapE from Enterococcus faecium reveals new insights into DapE/ArgE subfamily ligand specificity

Authors: Manuel Terrazas-López, Lilian González-Segura, Adelaida Díaz-Vilchis, Kelly Annecy Aguirre-Mendez, Naún Lobo-Galo, Alejandro Martínez-Martínez, Ángel G Díaz-Sánchez

Journal: Int J Biol Macromol

PubMed ID: 38740150

Doi: 10.1016/j.ijbiomac.2024.132281

Products & Services: Mutagenesis Services

Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells

Authors: Renate L M Jansen, Rinse de Boer, Eline M F de Lange, Janet Koster, Rifka Vlijm, Hans R Waterham, Ida J van der Klei

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38762172

Doi: 10.1016/j.bbamcr.2024.119754

Products & Services: Molecular Biology Reagents

Biosynthetic production of anticoagulant heparin polysaccharides through metabolic and sulfotransferases engineering strategies

Authors: Jian-Qun Deng, Yi Li, Yu-Jia Wang, Ya-Lin Cao, Si-Yu Xin, Xin-Yu Li, Rui-Min Xi, Feng-Shan Wang & Ju-Zheng Sheng

Journal: Nat Commun

PubMed ID: 38704385

Doi: 10.1038/s41467-024-48193-5

Products & Services: Gene Synthesis

Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants

Authors: Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson, Thea K. Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L. Powell, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen & Rasmus Hartmann-Petersen

Journal: Nat Commun

PubMed ID: 38740822

Doi: 10.1038/s41467-024-48481-0

Products & Services: Mutagenesis Services

A glutathione S-transferase from confers resistance to Fusarium head blight in wheat

Authors: Lanfei Zhao, Amy Bernardo, Fanmei Kong, Wei Zhao, Yanhong Dong, Hyeonju Lee, Harold N Trick, Jessica Rupp Noller, Guihua Bai

Journal: Phytopathology

PubMed ID: 38709206

Doi: 10.1094/PHYTO-03-24-0106-SC

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Development of advanced control material for reverse transcription-mediated bacterial nucleic acid amplification tests

Authors: Janessa D Lewis , Stephen J Salipante

Journal: J Clin Microbiol

PubMed ID: 38629844

Doi: 10.1128/jcm.00243-24

Products & Services: Gene Synthesis

CRISPR/Cas13a-based supersensitive circulating tumor DNA assay for detecting EGFR mutations in plasma

Authors: Li Wang , Xiaosha Wen , Yang Yang , Zheng Hu , Jing Jiang , Lili Duan , Xiaofen Liao , Yan He , Yaru Liu , Jing Wang , Zhikun Liang , Xiaoya Zhu , Quan Liu , Tiancai Liu , Dixian Luo

Journal: Commun Biol

PubMed ID: 38806596

Doi: 10.1038/s42003-024-06368-2

Products & Services: Plasmid DNA Preparation

Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity

Authors: Min Wu, Guangping Song, Jianing Li, Zengqing Song, Bing Zhao, Liyun Liang, Wenlong Li, Huaibin Hu, Haiqing Tu, Sen Li, Peiyao Li, Biyu Zhang , Wen Wang, Yu Zhang , Wanpeng Zhang, Weifan Zheng, Jiarong Wang, Yuqi Wen, Kai Wang, Ailing Li, Tao Zhou, Yucheng Zhang, Huiyan Li

Journal: Cell

Doi: 10.1016/j.cell.2024.04.027

Products & Services: Catalog Peptides

The TIMELESS and PARP1 interaction suppresses replication-associated DNA gap accumulation

Authors: Joanne Saldanha , Julie Rageul , Jinal A Patel , Amy L Phi , Natalie Lo , Jennifer J Park , Hyungjin Kim

Journal: Nucleic Acids Res

PubMed ID: 38801073

Doi: 10.1093/nar/gkae445.

Products & Services: PCR Cloning and Subcloning

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